LOCUS       NM_147138               1770 bp    mRNA    linear   ROD 15-DEC-2024
DEFINITION  Rattus norvegicus ZW10 interacting kinetochore protein (Zwint),
            mRNA.
ACCESSION   NM_147138
VERSION     NM_147138.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1770)
  AUTHORS   Han,M., Xiao,X., Yang,Y., Huang,R.Y., Cao,H., Zhao,Z.Q. and
            Zhang,Y.Q.
  TITLE     SIP30 is required for neuropathic pain-evoked aversion in rats
  JOURNAL   J Neurosci 34 (2), 346-355 (2014)
   PUBMED   24403136
  REMARK    GeneRIF: our results highlight SIP30 as a target to mediate
            neuropathic pain-evoked negative emotion
REFERENCE   2  (bases 1 to 1770)
  AUTHORS   Dai,C., Liang,D., Li,H., Sasaki,M., Dawson,T.M. and Dawson,V.L.
  TITLE     Functional identification of neuroprotective molecules
  JOURNAL   PLoS One 5 (11), e15008 (2010)
   PUBMED   21124846
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1770)
  AUTHORS   Peng,G., Han,M., Du,Y., Lin,A., Yu,L., Zhang,Y. and Jing,N.
  TITLE     SIP30 is regulated by ERK in peripheral nerve injury-induced
            neuropathic pain
  JOURNAL   J Biol Chem 284 (44), 30138-30147 (2009)
   PUBMED   19723624
  REMARK    GeneRIF: there is an ERK-responsive region in the rat sip30
            promoter. Activation of ERK promotes the recruitment of the
            transcription factor cyclic AMP-response element-binding protein to
            the sip30 gene promoter
REFERENCE   4  (bases 1 to 1770)
  AUTHORS   Wang,H., Hu,X., Ding,X., Dou,Z., Yang,Z., Shaw,A.W., Teng,M.,
            Cleveland,D.W., Goldberg,M.L., Niu,L. and Yao,X.
  TITLE     Human Zwint-1 specifies localization of Zeste White 10 to
            kinetochores and is essential for mitotic checkpoint signaling
  JOURNAL   J Biol Chem 279 (52), 54590-54598 (2004)
   PUBMED   15485811
REFERENCE   5  (bases 1 to 1770)
  AUTHORS   Lee,H.K., Safieddine,S., Petralia,R.S. and Wenthold,R.J.
  TITLE     Identification of a novel SNAP25 interacting protein (SIP30)
  JOURNAL   J Neurochem 81 (6), 1338-1347 (2002)
   PUBMED   12068081
REFERENCE   6  (bases 1 to 1770)
  AUTHORS   Van Hooser,A.A., Ouspenski,I.I., Gregson,H.C., Starr,D.A.,
            Yen,T.J., Goldberg,M.L., Yokomori,K., Earnshaw,W.C., Sullivan,K.F.
            and Brinkley,B.R.
  TITLE     Specification of kinetochore-forming chromatin by the histone H3
            variant CENP-A
  JOURNAL   J Cell Sci 114 (Pt 19), 3529-3542 (2001)
   PUBMED   11682612
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Nov 27, 2020 this sequence version replaced NM_147138.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF532776.1, BC063144.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840105, SAMN12840110
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-125               JAXUCZ010000020.1  15953079-15953203   c
            126-216             JAXUCZ010000020.1  15951973-15952063   c
            217-343             JAXUCZ010000020.1  15951706-15951832   c
            344-510             JAXUCZ010000020.1  15951344-15951510   c
            511-567             JAXUCZ010000020.1  15951168-15951224   c
            568-707             JAXUCZ010000020.1  15950867-15951006   c
            708-824             JAXUCZ010000020.1  15950670-15950786   c
            825-1770            JAXUCZ010000020.1  15937396-15938341   c
FEATURES             Location/Qualifiers
     source          1..1770
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p11"
     gene            1..1770
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /note="ZW10 interacting kinetochore protein"
                     /db_xref="GeneID:257644"
                     /db_xref="RGD:628671"
     exon            1..125
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..822
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /note="ZW10 interacting protein-1; scoilin;
                     neuroprotective protein 8; SNAP25-interacting protein 30;
                     ZW10 interactor, kinetochore protein"
                     /codon_start=1
                     /product="outer kinetochore KNL1 complex subunit ZWINT"
                     /protein_id="NP_671479.1"
                     /db_xref="GeneID:257644"
                     /db_xref="RGD:628671"
                     /translation="MADAEKNAVAEKNAVAEENAVAEENAVADKNATKEVLAEAASVL
                     EPVGLPEEAELPAKIMEEFMRNSRKKDKLLCSQLQVVNFLQTFLAQEDNTDQNPDALA
                     SEDTSRQKATETKEQWKELKATYMDHVDVIKCALSEALPQVKEAHRKYTELQKAFEQL
                     EAKKRVLEEKLQLAQKQWVLQQKRLQNLTKISAEVKRRRKRALEKLDGSHQELETLKQ
                     QAGQEQEKLQRNQSYLQLLCSLQNKLVISESKADDKDVKGPALPPKSP"
     exon            126..216
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            217..343
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            344..510
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            511..567
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            568..707
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            708..824
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
     exon            825..1770
                     /gene="Zwint"
                     /gene_synonym="Sip30; Zwint-1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgtggtgg gcgtcagaac catggcggac gcggagaaaa acgctgttgc ggagaaaaac
       61 gctgttgcgg aggaaaacgc cgttgcggag gaaaacgccg ttgcggataa aaacgcaacg
      121 aaagaggttc tggctgaggc agcaagcgtt ctggaacctg taggattgcc ggaagaagca
      181 gagctgcctg ccaagatcat ggaggaattt atgaggaact ctcggaagaa agacaagctg
      241 ctctgtagcc agcttcaagt agtgaacttc ttacagactt ttctggccca ggaggataat
      301 actgaccaga acccagatgc tctggcttct gaagatacaa gtcgacaaaa ggcaactgaa
      361 actaaggagc agtggaagga gctgaaggca acatacatgg atcatgtgga cgtcatcaaa
      421 tgtgccctgt ctgaggcctt gccccaggtt aaagaggcac acaggaagta caccgagctt
      481 cagaaggctt ttgagcaact tgaggctaag aagcgagtcc ttgaggagaa actgcagtta
      541 gctcagaagc agtgggtgct gcagcagaag cgtttgcaga atctgacaaa gatttctgct
      601 gaggtcaaga gacgccggaa gagagctctg gagaagcttg atggttctca ccaggaactt
      661 gaaaccttga agcagcaagc aggacaggag caggagaagc tgcagaggaa ccagagctac
      721 ctccagctgc tgtgctccct gcagaataag ctggtcatct ctgagtccaa ggccgacgac
      781 aaagatgtca aagggcccgc ccttccaccc aagtctccgt aaagatgaaa gcgagaagag
      841 agctgcgctc cagctgtgct gcttgggctg agaccagagt ggttccttcg ctgttgtatc
      901 cctaggccta ggcctgtagc cttgtacaat cttccaagcg gactcagttt ggcatctctt
      961 ggcttctcag tgaattgttc tgtttcattt cttaccatat attctggctt gttctgtctt
     1021 cacctgggtc caacttgctg tttctgtaaa attgtgccag tgaaattgtc acgtgcatgc
     1081 acgcaggcac acaggcacgc atgccacaac cacccttttc tctcgctgat cttcagtagt
     1141 ctctcctctg gccctctctc tctctgtctt ctctcccgac cagatgtgaa agtaacttta
     1201 tgcacccgat gtaattgttg cctcggaggc tcattgatga ataagctcac cctgtgtagt
     1261 tcttgctaaa ctctggctgg ctggttcaac tcagctcttc tggttcaaac ccgtctccaa
     1321 actgactgat tgaaacaggc ctctcttggc ttggaaagtc tgctctgaac tccagaactg
     1381 aacggtactg actgcactga ctcgactgaa cgcaactgca ccgagttgat tgactccttc
     1441 tccctttact gctcttaagt accctctctt ccctgtgctg tcctcctgag tcatgctgcc
     1501 aaatctttct ctgattcatc acttcgcccc tcaattagac tggcaatttc aaacgtggca
     1561 cttagcattt cagttgtagt cacttaatac tgcattcaga acttgagtct attgaatcca
     1621 taatgtgaaa ccatgtcttc gtgactgtga cctcactact cagtattgtg taaaagtttt
     1681 aggaactctc caagtaagca cttggtattt gctcattgat agaacagaaa aatgctgtgt
     1741 agataataaa taaacacggc tataagatta
//
