LOCUS       NM_001024801            2454 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zw10 kinetochore protein (Zw10), mRNA.
ACCESSION   NM_001024801 XM_343386
VERSION     NM_001024801.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2454)
  AUTHORS   Li,D., Zhao,Y.G., Li,D., Zhao,H., Huang,J., Miao,G., Feng,D.,
            Liu,P., Li,D. and Zhang,H.
  TITLE     The ER-Localized Protein DFCP1 Modulates ER-Lipid Droplet Contact
            Formation
  JOURNAL   Cell Rep 27 (2), 343-358 (2019)
   PUBMED   30970241
REFERENCE   2  (bases 1 to 2454)
  AUTHORS   Civril,F., Wehenkel,A., Giorgi,F.M., Santaguida,S., Di Fonzo,A.,
            Grigorean,G., Ciccarelli,F.D. and Musacchio,A.
  TITLE     Structural analysis of the RZZ complex reveals common ancestry with
            multisubunit vesicle tethering machinery
  JOURNAL   Structure 18 (5), 616-626 (2010)
   PUBMED   20462495
REFERENCE   3  (bases 1 to 2454)
  AUTHORS   Starr,T., Sun,Y., Wilkins,N. and Storrie,B.
  TITLE     Rab33b and Rab6 are functionally overlapping regulators of Golgi
            homeostasis and trafficking
  JOURNAL   Traffic 11 (5), 626-636 (2010)
   PUBMED   20163571
REFERENCE   4  (bases 1 to 2454)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   5  (bases 1 to 2454)
  AUTHORS   Chan,Y.W., Fava,L.L., Uldschmid,A., Schmitz,M.H., Gerlich,D.W.,
            Nigg,E.A. and Santamaria,A.
  TITLE     Mitotic control of kinetochore-associated dynein and spindle
            orientation by human Spindly
  JOURNAL   J Cell Biol 185 (5), 859-874 (2009)
   PUBMED   19468067
REFERENCE   6  (bases 1 to 2454)
  AUTHORS   Arasaki,K., Uemura,T., Tani,K. and Tagaya,M.
  TITLE     Correlation of Golgi localization of ZW10 and centrosomal
            accumulation of dynactin
  JOURNAL   Biochem Biophys Res Commun 359 (3), 811-816 (2007)
   PUBMED   17560939
  REMARK    GeneRIF: targeting of ZW10 to the perinuclear Golgi region was
            found to depend on the perinuclear accumulation of dynactin
REFERENCE   7  (bases 1 to 2454)
  AUTHORS   Wang,H., Hu,X., Ding,X., Dou,Z., Yang,Z., Shaw,A.W., Teng,M.,
            Cleveland,D.W., Goldberg,M.L., Niu,L. and Yao,X.
  TITLE     Human Zwint-1 specifies localization of Zeste White 10 to
            kinetochores and is essential for mitotic checkpoint signaling
  JOURNAL   J Biol Chem 279 (52), 54590-54598 (2004)
   PUBMED   15485811
REFERENCE   8  (bases 1 to 2454)
  AUTHORS   Hirose,H., Arasaki,K., Dohmae,N., Takio,K., Hatsuzawa,K.,
            Nagahama,M., Tani,K., Yamamoto,A., Tohyama,M. and Tagaya,M.
  TITLE     Implication of ZW10 in membrane trafficking between the endoplasmic
            reticulum and Golgi
  JOURNAL   EMBO J 23 (6), 1267-1278 (2004)
   PUBMED   15029241
REFERENCE   9  (bases 1 to 2454)
  AUTHORS   Van Hooser,A.A., Ouspenski,I.I., Gregson,H.C., Starr,D.A.,
            Yen,T.J., Goldberg,M.L., Yokomori,K., Earnshaw,W.C., Sullivan,K.F.
            and Brinkley,B.R.
  TITLE     Specification of kinetochore-forming chromatin by the histone H3
            variant CENP-A
  JOURNAL   J Cell Sci 114 (Pt 19), 3529-3542 (2001)
   PUBMED   11682612
REFERENCE   10 (bases 1 to 2454)
  AUTHORS   Chan,G.K., Jablonski,S.A., Starr,D.A., Goldberg,M.L. and Yen,T.J.
  TITLE     Human Zw10 and ROD are mitotic checkpoint proteins that bind to
            kinetochores
  JOURNAL   Nat Cell Biol 2 (12), 944-947 (2000)
   PUBMED   11146660
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC097452.1.
            
            [WARNING] On Apr 23, 2024 this sequence was replaced by
            NM_001024801.2.
            
            On Jun 10, 2005 this sequence version replaced XM_343386.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097452.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2454
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q23"
     gene            1..2454
                     /gene="Zw10"
                     /note="zw10 kinetochore protein"
                     /db_xref="GeneID:363059"
                     /db_xref="RGD:1309197"
     exon            1..188
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     CDS             84..2417
                     /gene="Zw10"
                     /note="ZW10 homolog, centromere/kinetochore protein; ZW10,
                     kinetochore associated, homolog"
                     /codon_start=1
                     /product="centromere/kinetochore protein zw10 homolog"
                     /protein_id="NP_001019972.1"
                     /db_xref="GeneID:363059"
                     /db_xref="RGD:1309197"
                     /translation="MASFVTEVLAHSGSLEKEDLGTRISRLTRRVEEIKGEVCNMISK
                     KYSEFLPTMQSAQALVTQVDTLSNDIDQLKSRIETEVCRDLHISTVEFTNLKQRLERD
                     SVVLNLLKQLQEFSSAIEEYNSALAEKKYIPAARLLEEAQECLKLLKSKKCFDLKMLK
                     SLSMELTVQKQNILYHLGEDWQKLVVWKFPPSKDTSSLESCLQTELHLCTEQPEKEMT
                     PLPSISSVLLAFSILGELPTKLKSFGQMLLKYILKPLVTCPSLHAVIERQPNSVSICF
                     QSLATDSEHPPPPEAFAKIQLVLEVLQKQLLDLPLDADLEIGKVPEIVLAEMLGEVIW
                     EDLSDCLIRNCLVYSIPTNSSKLQQYEEIIQSTEEFEKSLKEMRFLKGDTTDLLKYAR
                     NINSHFANKKCQDVIVAARHLMTSEIHNTVKIGPDCEETLPDLPSPDADHRLQVQVCK
                     VQFTDAGNLEPETSLDPRSFSLPTCRISEAVKKLMELAYQTLLEATTSSDQCAVQLFY
                     SVRNIFHLFHDVVPTYHKENLQKLPQLAAIHHNNCMYIAHHLLTLGHQFRSRLTPILC
                     DGTTTFVDLVPGFRRLGTECFLAQMRTQKGELLERLSSARSFANMDDEENYSAASKAV
                     RQVLHQLKRLGIVWQDVLPVNIYCKAMGTLLNTVIAEMIGRITALEDISTEDGDRLYS
                     LCKTVMDEGPQVFAPLSDENKNKKYQEEVPVYVSKWMPFKELMIMLQASLQEIGDRWA
                     DGKGPLATAFPSSEVKALIRALFQNTERRAAALAKIK"
     exon            189..323
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            324..425
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            426..503
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            504..663
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            664..813
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            814..1005
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1169
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1170..1352
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1353..1588
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1589..1660
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1661..1830
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1831..1961
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            1962..2093
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            2094..2296
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
     exon            2297..2427
                     /gene="Zw10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggcgaggcc gctggcggga cccgagctgc ggtgctggct gctggagtga cctatcctgt
       61 tggtgtgggt acgcttcgtg gcaatggctt ctttcgtgac ggaagtcttg gcccactcgg
      121 ggagcctgga gaaggaggat ctgggcacca ggatcagccg tctgacccgg cgggtggagg
      181 agatcaaggg cgaggtgtgc aatatgatca gcaagaagta cagtgaattc ctgcctacca
      241 tgcagagcgc acaggccctc gtcacccagg tggacactct atccaatgac atcgaccagc
      301 tgaaatccag gatagagact gaggtctgtc gggatcttca catatcaact gttgagttta
      361 cgaacttgaa gcagcggctg gaaagagact ctgtcgtcct aaatttgctc aaacagctgc
      421 aagagttttc ttctgctatt gaagagtata acagtgcact ggcagagaag aaatacatcc
      481 ctgctgctcg gctcctggag gaggcacagg aatgcttgaa gttattaaaa tcaaaaaaat
      541 gctttgactt aaaaatgttg aagtctctca gcatggagct cacggtacag aagcagaaca
      601 tcctttacca cctgggagaa gactggcaga agctggttgt atggaagttc ccgccatcaa
      661 aagataccag cagcttagaa tcttgtctac aaacagaact tcatttatgc actgagcagc
      721 ccgagaagga gatgactcct ctgccatcca tcagctctgt cctcttggcg ttttctattc
      781 ttggagaatt acccaccaag ctgaagtcat ttggtcagat gctgctgaag tatatactta
      841 agcctctggt gacttgcccg tcgctccatg ctgtgattga aaggcagccg aattcagtta
      901 gcatttgttt ccagtctctg gcgacggact cagaacatcc accaccaccc gaagcttttg
      961 caaagatcca gttggtattg gaagtgctcc agaaacagct tctagatttg cctcttgatg
     1021 ctgacctaga aattggaaaa gtccctgaga tcgtgttggc tgagatgctt ggtgaggtga
     1081 tctgggagga cctgtccgat tgcctcatca gaaactgctt ggtttactct attcccacca
     1141 atagcagcaa gctacagcaa tatgaggaga tcatacagtc cacagaggaa tttgaaaagt
     1201 ccctaaaaga gatgagattt ttaaaaggag atactactga cttgctgaaa tatgctcgca
     1261 atatcaattc tcattttgct aataagaagt gccaggatgt gattgtggcg gctagacatc
     1321 taatgacctc cgaaattcac aacaccgtga agattggtcc tgattgtgag gaaaccctac
     1381 cagacttgcc cagtcctgat gccgaccaca ggctacaagt gcaggtgtgc aaagtgcagt
     1441 tcaccgatgc cggaaactta gagcccgaga cttcgctgga ccctcggtcc ttctctttac
     1501 ccacgtgccg catcagtgag gctgtgaaga agttaatgga gctcgcttat cagactttac
     1561 ttgaggcaac aacaagtagc gaccaatgtg ctgtccagct tttttactca gtgagaaata
     1621 tcttccattt gttccatgat gtggtgccca cataccacaa ggagaacctt cagaagcttc
     1681 cccagttggc tgccattcac cataacaact gcatgtatat tgctcaccac ttgctgaccc
     1741 tcggccatca gttcagatcg cggctcaccc ccattctttg tgatggcacg accacttttg
     1801 tggaccttgt acctggcttc agaagacttg ggacggagtg ttttttggcc cagatgcgga
     1861 cccagaaagg agaacttctg gagagattat caagtgctag aagctttgca aacatggatg
     1921 atgaagagaa ttattctgca gcgagcaagg cagtgaggca ggtgctgcac cagctgaaga
     1981 gacttgggat cgtgtggcag gatgtcctgc cggtgaacat atactgcaag gctatgggga
     2041 ccttgctgaa caccgtgatt gctgagatga ttggcaggat cactgctcta gaggacatct
     2101 cgactgaaga tggcgataga ttgtattccc tgtgcaaaac agtgatggat gaagggccac
     2161 aagtatttgc acctctgtct gatgaaaaca aaaacaagaa ataccaagaa gaggttccgg
     2221 tctatgtgtc caagtggatg cctttcaaag aactcatgat aatgctacaa gctagcttgc
     2281 aggaaatcgg agatcggtgg gcagatggaa aagggcccct ggcaactgca ttcccttcca
     2341 gcgaagtaaa agctttaatt cgtgccttgt tccagaacac agaaagaaga gcggctgccc
     2401 ttgctaagat taaatagctc ccccttcaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
