LOCUS       NM_031616               2888 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zinc finger RANBP2-type containing 2 (Zranb2),
            mRNA.
ACCESSION   NM_031616 XM_017591057
VERSION     NM_031616.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2888)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2888)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 2888)
  AUTHORS   Li,R., Xi,Y., Liu,X., Chen,G., Wang,B., Jiang,L. and Li,W.
  TITLE     Expression of IL-1alpha, IL-6, TGF-beta, FasL and ZNF265 during
            sertoli cell infection by ureaplasma urealyticum
  JOURNAL   Cell Mol Immunol 6 (3), 215-221 (2009)
   PUBMED   19567205
  REMARK    GeneRIF: Data show that with the help of negative regulators
            TGF-beta and FasL, the high levels of IL-1alpha and IL-6
            expressions were observed in the early stages of the infection, and
            decreased gradually in the later weeks both in vitro and in vivo.
REFERENCE   4  (bases 1 to 2888)
  AUTHORS   Shakib,K., Norman,J.T., Fine,L.G., Brown,L.R. and
            Godovac-Zimmermann,J.
  TITLE     Proteomics profiling of nuclear proteins for kidney fibroblasts
            suggests hypoxia, meiosis, and cancer may meet in the nucleus
  JOURNAL   Proteomics 5 (11), 2819-2838 (2005)
   PUBMED   15942958
REFERENCE   5  (bases 1 to 2888)
  AUTHORS   Karginova,E.A., Pentz,E.S., Kazakova,I.G., Norwood,V.F., Carey,R.M.
            and Gomez,R.A.
  TITLE     Zis: a developmentally regulated gene expressed in juxtaglomerular
            cells
  JOURNAL   Am J Physiol 273 (5), F731-F738 (1997)
   PUBMED   9374836
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1, FN805251.1 and FM078527.1.
            
            On or before Nov 25, 2020 this sequence version replaced
            XM_017591057.1, NM_031616.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC087012.1, FQ211774.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-178               JAXUCZ010000002.1  249232010-249232187
            179-810             FN805251.1         1-632
            811-822             JAXUCZ010000002.1  249239242-249239253
            823-1355            FM078527.1         8-540
            1356-2888           JAXUCZ010000002.1  249244254-249245786
FEATURES             Location/Qualifiers
     source          1..2888
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q45"
     gene            1..2888
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /note="zinc finger RANBP2-type containing 2"
                     /db_xref="GeneID:58821"
                     /db_xref="RGD:61854"
     exon            1..286
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     CDS             231..1223
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /note="zinc finger, splicing; zinc finger protein 265;
                     zinc finger, RAN-binding domain containing 2"
                     /codon_start=1
                     /product="zinc finger Ran-binding domain-containing
                     protein 2"
                     /protein_id="NP_113804.2"
                     /db_xref="GeneID:58821"
                     /db_xref="RGD:61854"
                     /translation="MSTKNFRVSDGDWICPDKKCGNVNFARRTSCNRCGREKTTEAKM
                     MKAGGTEIGKTLAEKSRGLFSANDWQCKTCSNVNWARRSECNMCNTPKYAKLEERTGY
                     GGGFNERENVEYIEREESDGEYDEFGRKKKKYRGKAVGPASILKEVEDKESEGEEEDE
                     DEDLSKYKLDEDEDEDDADLSKYNLDASEEEDSNKKKSNRRSRSKSRSSHSRSSSRSS
                     SPSSSRSRSRSRSRSSSSSQSRSHSGSREHSRSRGSKSRSSSRSHRGSSSPRKRSYSS
                     SSSSPERDRKRSRSRPSSPAVRKKRRTRSRSPERHHRSSSGSTHSGSRSSSKKK"
     exon            287..339
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            340..448
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            449..531
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            532..608
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            609..743
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            744..913
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            914..1000
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            1001..1159
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..2888
                     /gene="Zranb2"
                     /gene_synonym="Zfp265; Zis; Znf265"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aacgcctgct caggaactcc gtgaggccgc atcgaggccg agcttctgga ccagctgctg
       61 actctagggc gtcgtctccg cactgctgct ccaggctcgc tgtcaggcgg tctgcgttct
      121 cccccacccc caggggaggg cgggtccggc ggcgcgcgga cagcccggcg cgaggccccg
      181 cggctccggt ggggacgtcg ctgcgggcgg cactgctgct ggcgtccaag atgtcgacca
      241 agaatttccg agttagtgac ggggactgga tctgccctga caagaagtgt ggaaatgtaa
      301 acttcgccag aagaaccagc tgtaacagat gtggtcgaga gaagacaact gaggccaaga
      361 tgatgaaagc tgggggaaca gaaataggaa agacactggc agagaagagc cggggcttat
      421 ttagtgccaa tgattggcag tgcaaaactt gcagtaatgt gaattgggct agaagatcag
      481 agtgtaacat gtgtaatact ccaaagtatg ctaaattaga agaaagaaca ggatatggag
      541 gtggttttaa tgaaagagag aatgttgaat acatagaaag agaagaatct gatggggaat
      601 atgatgagtt tggacgtaaa aagaaaaaat acagggggaa ggcagttggt cctgcatcta
      661 tattaaagga agtcgaagat aaagaatcag agggagaaga agaggatgag gatgaagatc
      721 tctctaaata taagctagat gaggacgagg atgaagatga tgctgatctc tcaaaatata
      781 atcttgatgc cagtgaagag gaagatagta acaaaaagaa aagcaatagg cggagccgct
      841 caaagtctcg atcgtctcac tcaaggtctt catcacgctc atcctccccc tcaagttcaa
      901 ggtccaggtc caggtcccgt tcaagaagct cttccagctc gcagtccagg tctcactccg
      961 gttccagaga acattccaga tcccgtggtt cgaaatcaag atccagctcc aggtcccaca
     1021 ggggctcttc ttccccaaga aaaagatctt actcgagttc ttcatcatct cctgaaagag
     1081 acaggaagag gagtcgctct agaccttctt caccagctgt tcgcaaaaaa agacgaacga
     1141 gatcacggtc acccgaaagg caccacaggt cgtcctccgg atcaacccat tctggttccc
     1201 gttcaagttc aaaaaagaaa taatgtatta aaatttacat ctttaaaaaa cattgagtac
     1261 agtgcatgaa gcatattttt taggaagttg atgtctcatt tggtcagaag tactacatct
     1321 gctagtagag gtgcatgcct ttattgcttt tcaaaacaat aaaactgttc atttgtgaaa
     1381 ctgaaagtaa attgcatttt aagccatact gttccccaga taaatgctct gtccattatt
     1441 tacaaccatt tacttcgttt aaaaccatcc tagcgataac ggagtacttt tgtttcctac
     1501 tttaaatcct gtccttttca tttctaaatg ttctattggc agagacggtt gcctgggctt
     1561 gcctggactt cagacacata ggcaaagcta gtaagctagt tggagtaacc agttcctgtt
     1621 catgtgggaa tagtagtcaa cctggttatg ttctttacct atgccagtaa tttcttacca
     1681 gaggtaaagt acattgcaaa gctgacaact gggaacaagc tgagggtgcc ttagaatcat
     1741 tgtctcttac cagctttaca cctcttaatg caagaggatt atagaaatta cagaaggaaa
     1801 gggaaggtta accacatatt acttcaaaat gtctttctca aagtttaaga aatgtggata
     1861 tcctttaaat aaatctagtt accaaatgtt gtacttgatt gataaaagat ttttaaaaag
     1921 gctaaatcat agttaatgag ccaattgatg agagcttttg aaacttgttt ctcagtgaca
     1981 ggctaacaaa gacatgaatt taagtgaaca tttgccttgt gatgtctgat ttttaacatt
     2041 gtagatatct aagtaacaga agaattctta cttccccaca atttaagcaa aatcattttt
     2101 ctcacctgga aaaaaaaaca tatggcttaa aatgctttca gagttttatt tctcaaatta
     2161 aaatctggtc acttgagatc cattttgttc tctggtttaa aagttataag gtttctctta
     2221 acagtctttt cagcagcaaa agcaaggtaa gtatataagg gacaacagtt atgctggggc
     2281 tccttgtgag ggaattactt cctgtttctc ctttagtatt tgtctgctgc agtttaaata
     2341 taagtaaagc cttctgagat gtttagtaga cagatcaaac gaaatgtttt tattttaaag
     2401 tgagtgtttt tcttctcaac tgatctaaag atgaaaacaa aatatcgtac gtagaaatat
     2461 tttggtaata tttttacaag ctttcctgtg ttttttgtct tattttcctt gctgcattta
     2521 ctgtaggttg cacacgaact cttactctct tgtaattgtg cctcagactt ctcgaaagtc
     2581 gactttctga gttgcccaga tcttctagat ccgacgtgtt agccttggtt tgtttttgtg
     2641 ctttctgtat ttaaaacttg agctgtacta ggcaaatgca agattataaa tttagctaat
     2701 aggagtttac aaacagttca gatgattatg atttgatttg gtttaattga gctgtactag
     2761 ttcatttcat aaggaaatga tactgtagac aaatgtaaat aaaatctgtg agtcaaccat
     2821 caagtgttgt ttattagaaa taaactagga tgttctaagc tttgactgaa tgtcctaagc
     2881 tcataata
//
