LOCUS       XM_039092844            5642 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus zinc and ring finger 3 (Znrf3),
            transcript variant X1, mRNA.
ACCESSION   XM_039092844
VERSION     XM_039092844.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051349.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039092844.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5642
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..5642
                     /gene="Znrf3"
                     /note="zinc and ring finger 3; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 8
                     ESTs, 3 Proteins, and 100% coverage of the annotated
                     genomic feature by RNAseq alignments, including 14 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:685487"
                     /db_xref="RGD:1593771"
     CDS             232..2973
                     /gene="Znrf3"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase ZNRF3 isoform X1"
                     /protein_id="XP_038948772.1"
                     /db_xref="GeneID:685487"
                     /db_xref="RGD:1593771"
                     /translation="MRPRSGGRPGAPGRRRRRLRRGPRGRRLPPPPPLPLLLGLLLAA
                     AGPGAARAKETAFVEVVLFESSPSGDYTTHTTGLTGRFSRAGAMLSAEGEIVQMHPLG
                     LCNNNDEEDLYEYGWVGVVKLEQPELDPKPCLTVLGKAKRAVQRGATAVIFDVSENPE
                     AIDQLNQGSEDPLKRPVVYVKGADAVKLMNIVNKQKVARARIQHLPPRQPTEYFDMGI
                     FLAFFVVVSLVCLILLVKIKLKQRRSQNSMNRLAVQALEKMETRKFNSKSKGRREGSC
                     GALDTLSSGSTSDCAICLEKYIDGEELRVIPCTHRFHRKCVDPWLLQHHTCPHCRHNI
                     IEQKGNPGAVCVETSNLTRGRHPRVTLPVHYPGRVHRTNAIPAYPTRTSMDSHGNPVT
                     LLTMDRHGEQNLYSPQTPTYVRGYPPLHLDHTLAPHRCSLEHRAYSPAHPFRRPKFSS
                     RSFSKAACFSQYETMYQHYYFQGLSYPEQESQPVPSVTPRGQSRAFPPSGGSSLLFPT
                     MVHMAPPAHVESGSTSSFSCYHGHRSVCSGYLADCPGSDSSSNSSGQCRCSSSDSVVD
                     CTEVSNQGVYGSCSTFRSSLSSDYDPFIYRSRGPAVHLEGSPPPEELPAAHNQGAGRG
                     EPWLGPASPSGDQLSTCSLEMNYSSNSSLEPRGPNSSTSEVGLEVSPGAALDLRRTWK
                     GGPEGPSCACCFEPQPVTLGSGIGTTAGGSSLFLGPRLLEDCNPASGEPQLGSSQGLY
                     GLHSDHYPRTDGVKYEGLPCCFYEEKQVAHSAGRGNGCYTEDYSVSVQYTLTEEPPPS
                     CYAGARDLSQRIPIIPEDVDCDLGLPQDCQGRHSHSPWGGALGLDGPRLQWSLGTTRK
                     EEQAPCYQAEVQPGCSPEEADASRASLSSAPQDTQESLALAAEASGQEESRDVKVET"
ORIGIN      
        1 ggccgagcgc ggggagggag gggagagcgg gtcacgacgc tgcgggggcg gggataaccc
       61 ctcacgtgga gcagatgaaa gggccgcggc gcgacggccg ggggagcgga gcagagcctg
      121 cgacccacaa agccgccgcc gccgcgatgg tgctgtgagg cgctcggtcc tccgccggcc
      181 cgcgactatg cccggccgcg cccgccctcc gcgccctccc gccgcaggac catgaggcca
      241 cgctcgggcg ggcgcccagg ggccccgggc cgccgccgcc gtcgcctccg ccgcggcccc
      301 cgcggtcgtc gcctgccgcc gccgccgccg ctgccgctgc ttctcgggct gctgctggcg
      361 gccgcggggc ccggcgcggc gcgggccaag gagacggcgt tcgtggaggt ggtgctgttc
      421 gagtcgagcc cgagcggcga ctacaccacc cacaccaccg gcctcacggg ccgcttctcg
      481 cgggccgggg ccatgctcag cgccgagggc gagatcgtgc agatgcaccc actaggccta
      541 tgtaataaca atgacgaaga ggacttgtac gaatatggct gggtaggagt ggtgaagctc
      601 gaacagccag aattggaccc caaaccatgt ctcactgtcc tgggcaaggc caagagagca
      661 gttcagcggg gagctactgc cgttatcttt gacgtatctg aaaacccaga agccatcgac
      721 cagctaaacc aaggctctga agaccccctt aagaggccag tggtgtatgt gaagggtgca
      781 gatgctgtca agctgatgaa cattgtcaac aagcagaaag tagctcgagc aaggatccag
      841 cacctccctc ctcgacaacc caccgagtac tttgacatgg ggattttcct ggcattcttc
      901 gtcgtggtct ccttggtctg cctcattctc cttgtcaaaa tcaagctgaa gcagcgtcgt
      961 agtcagaatt ccatgaacag gctggccgtg caggctctgg agaagatgga aaccagaaag
     1021 ttcaactcca agagcaaggg gcgccgggaa ggaagctgtg gggccctgga tacacttagc
     1081 agcggctcca catccgactg tgccatctgt ctggagaagt acattgatgg agaggagctt
     1141 cgggtcatcc cgtgtaccca tcgattccac aggaagtgtg tggatccatg gctactgcag
     1201 catcatacct gtccccactg tcggcacaac atcatagaac aaaagggaaa tccaggtgct
     1261 gtttgtgtgg agacaagcaa ccttacccgt ggtcggcacc caagagtgac cctaccagta
     1321 cattacccag gccgtgtgca taggaccaat gccatcccag cctaccctac taggacaagt
     1381 atggactccc atggcaaccc tgtcacattg ctaaccatgg accggcatgg ggagcagaac
     1441 ctctattctc cacaaacacc cacctacgtc cgtggttacc cacccctgca cctggaccac
     1501 actctggccc ctcatcgctg cagcctggaa caccgggcct actcaccagc ccatcccttc
     1561 cgcaggccca agttcagcag ccgcagcttc tccaaggcag cttgcttctc ccagtatgag
     1621 accatgtacc aacactacta cttccagggt ctcagctacc cagagcagga gagccagccg
     1681 gtacctagcg tcacacccag gggccagtcc cgtgccttcc caccaagtgg tggcagcagc
     1741 ctgctcttcc ccaccatggt gcatatggcc cctccagccc atgtggagag tggcagcacg
     1801 tctagcttca gttgctacca cgggcaccgt tctgtgtgta gtggctacct ggctgactgt
     1861 cctggcagcg atagcagcag caacagctct ggccagtgcc gctgctcttc cagtgactct
     1921 gtggtggact gcacagaagt cagcaaccaa ggtgtgtatg ggagctgctc caccttccga
     1981 agctccctca gcagcgacta tgaccccttc atctaccgca gccgggggcc tgctgtgcac
     2041 cttgagggct ccccgccacc agaggagctt ccagcagccc acaatcaagg tgctgggcgg
     2101 ggtgagccat ggctaggccc tgcctctccc tcaggggacc agctgtccac ctgcagcctg
     2161 gagatgaact acagcagcaa ctcctcgctg gaacccagag ggcccaacag ctctacctca
     2221 gaagtggggc tcgaggtttc tcctggggcc gccctggacc tcaggaggac ctggaaaggg
     2281 ggcccagagg gaccatcatg tgcttgctgc tttgagcccc agcccgtcac gctgggctct
     2341 gggataggaa caactgcagg tggtagcagc ttattcctgg gtccccgact ccttgaggac
     2401 tgcaaccctg caagtgggga gccacaacta gggagctccc agggcctgta tggccttcac
     2461 tcagaccatt atcctaggac agatggggtg aaatatgagg gcctgccctg ctgcttctat
     2521 gaagagaagc aggtggccca cagtgctggc aggggcaatg gctgctacac tgaggactat
     2581 tcagtgagtg tgcagtacac actcaccgag gaacccccac ccagctgtta tgcaggggcc
     2641 cgggacttga gccagcgcat ccccattatt ccagaggatg tagactgtga cttgggcttg
     2701 ccccaagact gccaagggag gcacagccac agcccctggg gtggagcact gggcttggac
     2761 ggtccccgac tccaatggag tctggggaca acccggaaag aggaacaggc tccatgttac
     2821 caagctgagg tgcagcctgg ctgctctcca gaggaggcag atgcttccag ggctagcctc
     2881 tccagtgccc cccaggacac tcaggagtcc cttgccctgg ctgctgaggc ttcaggccaa
     2941 gaagaaagca gagatgtcaa agttgaaact tgaggaggga actcagaata attagcgggg
     3001 atctgtgtct gagtcttcac tacagcaacc aacattcgcc tggcacagtc tcgttaccga
     3061 atacctttgt atatgtcact gaggagtccc tagaaccctg tagagtctgc agaggtggat
     3121 ttaaaggtgg ggaagttgga attggcttgc ctgaggccac aaagtttagg aacttcatac
     3181 ccacagctga catctattgc ttactaagta agctccctat tctctgccaa gccatccaaa
     3241 aggcctttgc atgtgttgat ccatttattc ttcaaggaac cctgtgagag aagggccagt
     3301 gtcatcttat aagataaaat caagacacac actttagact tggaccctga cagccactcc
     3361 ctaagacata ctctgagttg tgctggccac cataaggtga ctgaactgga ctcagtttta
     3421 tgagtgcaag ttcacaggct acaggtacct cagctgggca tacataagca tacactgccc
     3481 acctccttcc tctttatttt ccatcatggt caactccctt ttgtctgtgt atatgaaagc
     3541 gtcctacaga actaaacgtc ggatggaccc taaatctcat cactagatct ggtgtaccat
     3601 ccctctatca cagagactta cctaccctaa tcctgtcttc aatttaagga ttttcgtcac
     3661 ctagtagtga aatccctgcc tttggcttgt ccttcttccc atccatctca ccactgcggg
     3721 ccattggtta cctctctgat gccacctgca aacctgtgct ctggagtgcc cagcagctgg
     3781 ccaagtgacc acttgctctt gatctttctt ttggctcttg gtgcctttca acattgtgct
     3841 gtcactggat ttccttcaag gattttgctt ctctgagctt ggaaagcaca ccaatagcac
     3901 ttacctctga gcacggcctt gaacagagag aatgacaatt agctggctct ttaccacttc
     3961 gcagtggtaa ggtcgtacct ggtgctgggt gctggtctgc tctgcacccg ttctgactgc
     4021 acagatgttg gtgggaccac atagcagtcc tgtagcctgg tgttgattga gatagattat
     4081 tggagcccat aggtagggat gctaggatct tgtcttacat tgattggtta ttagaaataa
     4141 aaggggaaat gattttttgt ccttgttaaa aagtagttcc catggaaaaa ctagagttat
     4201 gttaagagac taagctttga catcatttta tgtgttattc ctttgtccca gactttagaa
     4261 atcttgctgg gatttgtgtc tcctgctcat ctagacattt tttaatacca agtaagagaa
     4321 agatgtgaat ttttaaaggt catgatgttt tggttctgaa cagcatactg gggcaggaag
     4381 ctggagtcag aaaaagctca gtaggaacat aaggcagttt gcctgctgga aagatgagtc
     4441 cacagcaggc aggaaagaaa tgggaccatc ttgcaagact tctgtataag ccacagtcac
     4501 aactcctaca cacaatgcca ttcaaacaca aatgccagca ggtaagttct gctggactgt
     4561 gaatatacct tctaacctga tagcaagggc caggaaaagc cgctcagtgg ggaaatatac
     4621 tctgaagtcc ataaggaaca atattcttcc tgggactggg aaccatttgg atagattcaa
     4681 tcacagtaga agacctggct ttttaagaaa tatcacctat ataaaaatga aatcgggaat
     4741 agagaactca gcagtcgaga gctggctact attccagagg atccaacacc tctttctgac
     4801 ctccttgggc tcctgcacat aggtggtgca catattgttg acctttctgc ttgcatggga
     4861 aggagtcctg ggactcagaa gtccagcaac cacaaagctc tgagatgtcc caatgcaagg
     4921 gcctcctgag acaggagccc agaaaccaca cagctccgag aggaagcttc ctcagcacag
     4981 gcagtgtagc tcccacatga gggaggggat ccccagctga gctgaggcgc tctggagtct
     5041 caaccccact ccacttcttc ccttctcttg ataacttctt gtcttctggt gagagtcata
     5101 ccagccagca aatctcatga aagagatttt ttttggaagg tccagggtgt ggaggaacga
     5161 atccaggaga ggctgcctct actccagaga gggagcagac aattggacaa acgacaaaag
     5221 acagtgcttc tacaggggtt cttgggaggg tagagatttc cagggtgacg attggtggga
     5281 tttcaagtcc tgagcttaag ggagctcagg gcttggtgtg ttttttcaca cttaagggct
     5341 tggtgggttt tgtgggaagt tcagagatcg gtggcttttg ttcagacttc tcacctaaaa
     5401 ttagcataat ctgggaatgg tcctgctgag gggctaggga tgacctttgt gacagttaca
     5461 gaagctggaa acagttatga gagttcttcg ggctggtgcc tggtcacttt cctgccttga
     5521 gagtttacag aggttacaaa gggagtccgt gtggcattga aagcttttct tgcctcttaa
     5581 atggccttaa taatcaacac atatcaggct cacatacaca tatacctaat aaatatttta
     5641 aa
//
