LOCUS       NM_001395664            4764 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus Zic family member 5 (Zic5), mRNA.
ACCESSION   NM_001395664 XM_039093542
VERSION     NM_001395664.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4764)
  AUTHORS   Sakai-Kato,K., Ishiguro,A., Mikoshiba,K., Aruga,J. and
            Utsunomiya-Tate,N.
  TITLE     CD spectra show the relational style between Zic-, Gli-, Glis-zinc
            finger protein and DNA
  JOURNAL   Biochim Biophys Acta 1784 (7-8), 1011-1019 (2008)
   PUBMED   18298960
REFERENCE   2  (bases 1 to 4764)
  AUTHORS   Furushima,K., Murata,T., Kiyonari,H. and Aizawa,S.
  TITLE     Characterization of Opr deficiency in mouse brain: subtle defects
            in dorsomedial telencephalon and medioventral forebrain
  JOURNAL   Dev Dyn 232 (4), 1056-1061 (2005)
   PUBMED   15736266
REFERENCE   3  (bases 1 to 4764)
  AUTHORS   Ishiguro,A., Inoue,T., Mikoshiba,K. and Aruga,J.
  TITLE     Molecular properties of Zic4 and Zic5 proteins: functional
            diversity within Zic family
  JOURNAL   Biochem Biophys Res Commun 324 (1), 302-307 (2004)
   PUBMED   15465018
REFERENCE   4  (bases 1 to 4764)
  AUTHORS   Inoue,T., Hatayama,M., Tohmonda,T., Itohara,S., Aruga,J. and
            Mikoshiba,K.
  TITLE     Mouse Zic5 deficiency results in neural tube defects and hypoplasia
            of cephalic neural crest derivatives
  JOURNAL   Dev Biol 270 (1), 146-162 (2004)
   PUBMED   15136147
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000015.1.
            
            On Jul 30, 2021 this sequence version replaced XM_039093542.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360194.1542861.1,
                                           SRR26360176.403838.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840111 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1770              JAXUCZ010000015.1  105971900-105973669 c
            1771-4764           JAXUCZ010000015.1  105964932-105967925 c
FEATURES             Location/Qualifiers
     source          1..4764
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q25"
     gene            1..4764
                     /gene="Zic5"
                     /note="Zic family member 5"
                     /db_xref="GeneID:361095"
                     /db_xref="RGD:1310160"
     exon            1..1770
                     /gene="Zic5"
                     /inference="alignment:Splign:2.1.0"
     CDS             342..2213
                     /gene="Zic5"
                     /note="zinc finger protein of the cerebellum 5; Zic family
                     member 5 (odd-paired homolog, Drosophila)"
                     /codon_start=1
                     /product="zinc finger protein ZIC 5"
                     /protein_id="NP_001382593.1"
                     /db_xref="GeneID:361095"
                     /db_xref="RGD:1310160"
                     /translation="MMEPPLSKRNPPALRLADLATAQAQQLQNMTGFPVLAGPPAHSQ
                     RRAVAMHLHPRDLGTDPGVASTALGPEHMAQTSGHGPSPPTQALPELPQATAPAARSP
                     ASGTHPGARTHHDGGGSSGAQASAPPPPAPPLPPSQSSSPPPPPPPPPPALSGYTATN
                     SGGGGSSGKGHSRDFVLRRDLSATAPAAAMHGAPLGGEQRSGSSSPQHPTPPPHPAGM
                     FISASGTYAGRDGGGSALFPALHDSPGAPGGHPLNGQMRLGLAAAAAAAAELYGRAEP
                     PFAPRSGDAHYGAVAAAAAAALHGYGAVNLNLNLAAAAAAAAAAGPGPHLQHHAPPPA
                     PPPAPAPHPHHPHLPGAAGAFLRYMRQPIKRELICKWLDPEELAGPPAPADSGAKPCS
                     KTFGTMHELVNHVTVEHVGGPEQSSHVCFWEDCPREGKPFKAKYKLINHIRVHTGEKP
                     FPCPFPGCGKVFARSENLKIHKRTHTGEKPFKCEFDGCDRKFANSSDRKKHSHVHTSD
                     KPYYCKIRGCDKSYTHPSSLRKHMKIHCKSPPPSPGALGYSSVGTPVGDTLSPVLDPT
                     RSRSSTLSPQVTNLNEWYVCQAGGAPSHLHTPSSNGTTSESEDEEMYGNPEVMRTIH"
     exon            1771..4764
                     /gene="Zic5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggggcacg aagtgaaagc acaggcggtg tggtatgcgg gggcggtttc ccgctgggct
       61 cagagcctga accagagcca atcgcgcagc cgaggcagct gccaatcaca cggctccctc
      121 caatcccacc cgtgccattt ccaaaaactc ggtcccactg tgcagctcaa atgtagtgtt
      181 cactctgcca atcgctggag gatagagtgg ggacaagaat aagcagttag gaggcccgga
      241 cacaagaagt taaagagccc ctaatatata catgtttttg aaggcgggca gaggggggaa
      301 aagtaccccc aggaagggtc tatgggcctg attgtatagt tatgatggag ccccctttga
      361 gcaagaggaa cccgccagcg ttgagattag cggatttggc aacggctcag gcccaacagc
      421 ttcagaatat gacaggcttc ccggtgctgg ccggcccgcc cgcccactcc caacgccgcg
      481 cggtcgccat gcacctccac ccgcgggacc taggcactga ccccggcgtg gccagcactg
      541 ccctcggacc cgagcacatg gcacagacca gcgggcacgg ccccagtcct cccacccagg
      601 cgctcccaga gctgccccag gctaccgcac ccgccgcccg ctcccccgcc tcagggacgc
      661 acccgggagc ccgcacccac cacgatggcg ggggcagcag tggcgcgcag gcctcggcgc
      721 ccccgcctcc agcccctcct cttcctccct cccagtcctc ctctccccct cccccgcctc
      781 ctcctcctcc tcctgccctc tcgggctaca ctgccaccaa cagtggcggc ggcggcagca
      841 gcggcaaagg ccacagcagg gacttcgtcc tccggaggga cctttccgcc acggcccccg
      901 cggcggccat gcacggggcc ccgctcggag gggagcagcg gtccggcagc agctcccccc
      961 agcacccgac cccgcctccc cacccggccg ggatgttcat ctcggccagc ggcacctacg
     1021 cgggccggga cggcggcggc tccgcgctct ttcccgcgct gcacgactct cccggggctc
     1081 ctggcggcca cccactcaac ggccagatgc gcctggggct ggcggccgcc gcggcagctg
     1141 cagccgagct gtacggccgt gcagaaccac cctttgctcc gcgctcaggg gatgcgcact
     1201 acggggcggt ggcggccgcc gcggccgccg ccctgcacgg ctacggagcc gtgaacttaa
     1261 acctgaacct ggctgcggca gctgcagcgg cggcggccgc ggggcccggg ccccacctgc
     1321 aacaccacgc gccgcccccg gcgccaccgc cggcgcccgc gccgcacccg caccaccccc
     1381 acctcccggg ggcggccggg gccttcctgc gctacatgcg gcagccaatc aagcgggagc
     1441 tcatctgcaa gtggctggac cccgaggagc tggccgggcc gccggcgccc gcggacagcg
     1501 gcgccaaacc ctgttccaaa actttcggca ccatgcacga gctggtgaac cacgtcacag
     1561 tggagcacgt gggcggcccg gagcagagca gccacgtctg cttttgggag gactgtccgc
     1621 gcgagggcaa gcctttcaag gccaagtaca agctcatcaa ccacatccgc gtgcacaccg
     1681 gcgagaagcc cttcccctgc ccgttcccgg gctgcggcaa agtcttcgcg cgctccgaga
     1741 acctcaagat ccacaagcgc actcatacag gggaaaagcc tttcaaatgt gaatttgatg
     1801 gttgcgacag gaagtttgcc aatagcagtg atcggaagaa acactcccat gtccacacca
     1861 gcgacaagcc ctactactgt aagattcgag gctgtgacaa atcatacacc cacccaagct
     1921 ctctgaggaa gcatatgaag attcattgca agtccccccc accttctcct ggagctcttg
     1981 gttactcatc ggtggggact cccgtgggtg acactttgtc ccctgtgctg gacccaacca
     2041 ggagtcgatc cagcactctg tcccctcagg tgaccaacct caatgagtgg tatgtttgcc
     2101 aggccggtgg ggcccccagt catctccaca caccttccag caatggaacc acctctgagt
     2161 ctgaagacga ggaaatgtat gggaaccctg aagtcatgcg gacgatacat tagaattgtt
     2221 attaagtgag atagtaagtg ggagtccttg gaccatgtcc taacctgaaa caatgctgag
     2281 cctgagacaa actggtgatt cagacttgcc accgggtcta attagcccta tttattcagt
     2341 atgaaaccct atggtgtttg tacatttaat taatttaatt aagatatttg gttgtgggtt
     2401 ttttgttttt tgggggtttt tgttttgttt tgttttgttt tctttcctct ttctcctaaa
     2461 agaaacaaac acaaccacaa aataaaacag gactagagat gtagctcagt ggtagagtac
     2521 ttgcctagca tgcacgaggc cctgggtttt cagtctctag cactggggag gaaaagtaat
     2581 agcaaattaa aaagcaacta agttggactt gtacattgca gggagacagg cctggtgtca
     2641 gattctatca agggaaatga gtgggggaat tgagatataa cactgccaat acaatgtgtg
     2701 tgtgagcttg agtgtgcttg tgtgtgcgta cgtgtgtgtg tgtgtgtgtg tgtgtgtgtg
     2761 tgtgtgtgtg tgtgagagag aaatagggaa aaaagaatat taagtcagaa cttaacacat
     2821 caaccaggcc ctctccatgt cccagagttc ctctcagacg cctttgacac cataatgagg
     2881 gctgcttttg agccttctgg tagagactta attctgcaaa ggtctcttga ttgtaaaaca
     2941 cacacttgct gcactaacaa cagatcctgg accgtgcctg tatccaaaag tctttgtata
     3001 acaaacaaac aaacaaaact gtggtttcta atgtttatca ctttaattcc tctgctttta
     3061 ttatcaatct caatgtaaca taatattttt ttaatacagg attgttcctt cagtatcttg
     3121 tgtgatttaa aaaaaaagca aaaacaaaaa caaacaaaca aacaaacaaa aaaaaaaaac
     3181 aaatcaagcc aagtgcagcc accttaatat agctccatat atcgtgctac tgtgatagtt
     3241 caagcagaaa tggagaagag ttgctgagac agacagctgg ggaaactgtg atcttttgta
     3301 aaccagaagt aattcaagtg ctttctcttt cctctgctgg gttgtgctgt tttgattttt
     3361 aagtcgggag tttcagatgt tgcctcctgg ctgtacccaa attttgggag taataagcag
     3421 ttatgttttt gaccataagt tctttgggat gccaacatgc acagtgatgt ctaaggaagt
     3481 actaggattg catcctatcc atttttaaaa gaactttttt ttaaaaacaa gccaactcct
     3541 cttttatact actgtatcga cctttttctt ttttttctaa aaagaaaaaa aaaggtctct
     3601 atttttaatg tattttcttt cacctgtgcc acaaggactg aatcttcttc cctttgcaat
     3661 gacagtgtga agtgtatgat ttatattaca agaggaggag ttgctgtact tgttaaaaat
     3721 tttaagaggt ttatagttaa ccaccaaatg ctgatgaatg tgtgaccttt gccagagctg
     3781 tcaagccagg atacaaaggg tcaaggaccc aggacaataa cccttagtca gtttatgttc
     3841 ggttggtaca acacatctcc tgtgcaaact gtagcccatc agaaacacca tatacatatg
     3901 ctaaaggtac taatttatcc tcagagaccc tgaagacgcc ccctccccca tgatttgtag
     3961 aaatttgttt tgtgtgctgt gagtggttca tgtagtcttg tcattgttaa taacttgtct
     4021 gtgaatactt ttatttgtac agtttttaat taatttattt ttagagatcc ttttcttctg
     4081 gaagagttca aagcacacca aagaaatata ttatacattt tggcaaaaga ttgtcattta
     4141 tgacccatgg tttatttaag aaaaaaaaga aaaggaaaag aagtgggaaa atataaaata
     4201 tatttttaag cttacttgaa tggacaaggt aatgtgaaaa ctcgagactc ttcctgcacg
     4261 tctttttgcc tcgtgttgat gagattatgt atagtttata gatatattag tacagtgcat
     4321 ggtgctgtta cgtggacacc ttttaatgtt gtcttcagat tgttacagta aatatgaaac
     4381 atgcagaccc tcctttacaa agagagagac ctacaacttg aatataaaat aatcctacat
     4441 tttaaaggtt tatttgattt ttttttcctg ttattcactt tcaaatagaa aagataaggt
     4501 atgaatttgg gtgggataac ttatgtactg taagcttgtt aggacgaagt attcctgatg
     4561 tataacaagt tgttttattt atacaacttt ttcaatggta gtttgcacta ttctttatca
     4621 tgctacaggt ttatttatta tgaaacaaag gaatatgtat tttatgtatt ttgccataaa
     4681 taggttaact gccacaaatt tattggttcc tgatacactg aaaataaaac cttacaatgt
     4741 gtacctccct tagagagaaa gcaa
//
