LOCUS       NM_001108823            1866 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus zymogen granule protein 16B (Zg16b), mRNA.
ACCESSION   NM_001108823 XM_001054051 XM_008767589 XM_343866
VERSION     NM_001108823.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1866)
  AUTHORS   Pieragostino,D., Agnifili,L., Fasanella,V., D'Aguanno,S.,
            Mastropasqua,R., Di Ilio,C., Sacchetta,P., Urbani,A. and Del
            Boccio,P.
  TITLE     Shotgun proteomics reveals specific modulated protein patterns in
            tears of patients with primary open angle glaucoma naive to therapy
  JOURNAL   Mol Biosyst 9 (6), 1108-1116 (2013)
   PUBMED   23580065
REFERENCE   2  (bases 1 to 1866)
  AUTHORS   Bohm,D., Keller,K., Pieter,J., Boehm,N., Wolters,D., Siggelkow,W.,
            Lebrecht,A., Schmidt,M., Kolbl,H., Pfeiffer,N. and Grus,F.H.
  TITLE     Comparison of tear protein levels in breast cancer patients and
            healthy controls using a de novo proteomic approach
  JOURNAL   Oncol Rep 28 (2), 429-438 (2012)
   PUBMED   22664934
REFERENCE   3  (bases 1 to 1866)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   4  (bases 1 to 1866)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   5  (bases 1 to 1866)
  AUTHORS   Palmer,D.J., Kelly,V.C., Smit,A.M., Kuy,S., Knight,C.G. and
            Cooper,G.J.
  TITLE     Human colostrum: identification of minor proteins in the aqueous
            phase by proteomics
  JOURNAL   Proteomics 6 (7), 2208-2216 (2006)
   PUBMED   16502470
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On or before Dec 7, 2020 this sequence version replaced
            XM_008767589.2, NM_001108823.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR23984936.93775.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16093042, SAMN16093043
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-940               JAXUCZ010000010.1  13487806-13488745   c
            941-1046            JAXUCZ010000010.1  13487353-13487458   c
            1047-1152           JAXUCZ010000010.1  13487138-13487243   c
            1153-1866           JAXUCZ010000010.1  13484327-13485040   c
FEATURES             Location/Qualifiers
     source          1..1866
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1866
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /note="zymogen granule protein 16B"
                     /db_xref="GeneID:363551"
                     /db_xref="RGD:1562673"
     exon            1..940
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /inference="alignment:Splign:2.1.0"
     exon            941..1046
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /inference="alignment:Splign:2.1.0"
     CDS             992..1705
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /note="zymogen granule protein 16 homolog B; spermine
                     binding protein-like; pancreatic adenocarcinoma
                     up-regulated factor"
                     /codon_start=1
                     /product="pancreatic adenocarcinoma up-regulated factor
                     precursor"
                     /protein_id="NP_001102293.2"
                     /db_xref="GeneID:363551"
                     /db_xref="RGD:1562673"
                     /translation="MLLLLTLALLAGLTCSAQNVQGKNDAKYFYVKGEDVGDLKGIRI
                     FLSLLNFIKGIQLRFGNDWSDVYGSRSLKYKEFLLEDGEHVTQVSGTRKLCLTSLSFT
                     TNKERALTFGVRTGRSFDDSGGSDKHLVTVNGTHTPGLCITGMGFKWEVNTKDLKATE
                     PPREPVGSSEASDKKEDEGRDNDDVDDEDNNKDGDDGDDGDDGDDGDDGEDGEDGEDG
                     EDGEDDDGGDDNDGDEEEE"
     exon            1047..1152
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /inference="alignment:Splign:2.1.0"
     exon            1153..1866
                     /gene="Zg16b"
                     /gene_synonym="RGD1562673; Sbpl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcagggtt gttttgattt gtgcagaaga ttcttagtgt ggttatggac tcattgtccc
       61 agacaagggg tgagagccca gagctcggga actgtgaacc ggagagacca tgtaaaagac
      121 tcaagttgag gaccagtgcc ctggcagagc tggtcaccct ggaacaactg cccaacctgg
      181 ggccagattt tctggggacc ctagggaaga gaaatgtgtc ctagagagat gggagcagga
      241 agagtctgtg tgtcccaagg ccaggctgac atatcagggc taaagcactt ggttctcact
      301 gtctgattat aaaatggaca gcagagaggt ggcctcagag ctgcctggaa gaccaaggct
      361 gtgctgagaa ctctggctgc tcactggtgg gagctgctat gagcagcgtt tggaaacaga
      421 tgctgtaagt gaagactctg gaaaggtctc agatagcaat caatccataa aagggagggc
      481 ggtgggaggg aggtgggacc tatgcctgag cccgtccttc ccagtgaagt catgcgcaag
      541 acatatctgc tctccacaca cacgagctcg tgactctgca cacttccttt gcttaagaca
      601 aacttgtctc ttggctctgg atacccgctt tgccaggatt tatggaggcc gccaagtgtg
      661 accacaagcc tccctgtttc cgcagtaaaa ccatcctgtg acccggtggg attcaacagg
      721 gtactccctg catttgcaga ggacggcaca ggctgtgggt ttttgttcaa aggcagtgga
      781 gaagaacaca aatagtgtcc agcatgtcct ggaagtaagc cccacattct tgcaggaaag
      841 tttgtcaaga gcggaagtag ggaggcccca cggtggcatt ggcccagtga catcagggta
      901 taaagggaca agaaaaaggg gctaggagca cacagcccag agcttcctgg agtcttggca
      961 cctcccccag cgtccagaac cctcaggagc catgctgctg ttgctgacct tggctctcct
     1021 tgctggtctc acctgcagtg cccagaatgt ccagggcaaa aatgatgcca aatatttcta
     1081 cgttaaaggt gaagatgtgg gggatctcaa ggggatccgg atcttcctaa gtcttctaaa
     1141 cttcattaag ggcatccagc tgcggtttgg taatgactgg agtgacgtgt acggatcccg
     1201 gtcactaaaa tataaagagt tccttctgga ggatggagag cacgtgacac aggtgagcgg
     1261 caccagaaag ctctgcctga cttccctgag cttcactact aacaaggagc gagcgctcac
     1321 ctttggtgtt agaacaggcc gctcctttga tgacagtggt ggttctgaca agcatctagt
     1381 gactgtcaat ggtacacaca caccaggcct ctgcatcaca gggatgggct tcaaatggga
     1441 agttaataca aaggacttga aggccaccga gcctccgaga gagccagtgg gtagctctga
     1501 ggcttccgac aagaaggaag atgaaggcag agacaatgat gatgttgatg acgaagacaa
     1561 taacaaagat ggtgatgatg gtgatgatgg tgatgatggt gatgatggtg atgatggtga
     1621 ggatggtgag gatggtgagg atggtgagga tggtgaggat gatgatggtg gtgatgacaa
     1681 cgacggtgat gaggaagaag agtagcatgt tcagagctca gccctgcatc cccgcattcc
     1741 accacctcct ctcagccaag cttacccact cacagggacc aatagaccag gtgaccctgg
     1801 gctgaagtag gcaaagtcca aatgcccttt atctctctgt tcaataaagt atgtgcatct
     1861 atgtga
//
