LOCUS       NM_001107227            3980 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zinc finger FYVE-type containing 28 (Zfyve28),
            mRNA.
ACCESSION   NM_001107227 XM_001064974 XM_223537
VERSION     NM_001107227.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3980)
  AUTHORS   Mosesson,Y., Chetrit,D., Schley,L., Berghoff,J., Ziv,T.,
            Carvalho,S., Milanezi,F., Admon,A., Schmitt,F., Ehrlich,M. and
            Yarden,Y.
  TITLE     Monoubiquitinylation regulates endosomal localization of Lst2, a
            negative regulator of EGF receptor signaling
  JOURNAL   Dev Cell 16 (5), 687-698 (2009)
   PUBMED   19460345
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473963.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_223537.4, XM_001064974.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760393,
                              SAMEA5760396 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3980
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14q21"
     gene            1..3980
                     /gene="Zfyve28"
                     /note="zinc finger FYVE-type containing 28"
                     /db_xref="GeneID:305454"
                     /db_xref="RGD:1310151"
     exon            1..214
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     CDS             176..2893
                     /gene="Zfyve28"
                     /note="zinc finger, FYVE domain containing 28"
                     /codon_start=1
                     /product="lateral signaling target protein 2 homolog"
                     /protein_id="NP_001100697.1"
                     /db_xref="GeneID:305454"
                     /db_xref="RGD:1310151"
                     /translation="MMNRFRKWLYKPKRSDPQLLAQFYYADEELNQVAAELDSLDGRK
                     EPQRCTLLVSQFRSCQDNVLNIINQIMEECIPQDRAPRDFCVKFPEEIRHDNLAGQLW
                     FGAECLAAGSIIMNRELESMAMRPLAKELTRSLEDVRGTLRDQALRDLNTYTEKMREA
                     LRRFDVLFAEFELSYVSAMVPVKSPREYYVQQEVIVLFCETVERALEFGYLTQDMIDD
                     YEPALMFTIPRLAIVCGLVVYADGPLNLDRKVEDMSELFRPFHTLLRKIRDLLQALTE
                     EELHTLERSLCVSQDVELPIRADAQAPSALAPSFSASLAPEETLSASANNPEEELACS
                     MQYDDQELEELSRMVHRAGDEMSSLLSPPSACQSPAHRAGSEASPRGEASPARAQLKS
                     GSDEEERVFFMDDVEVTESPARPESPRSTFELTQGNVQQRGQDGQSGEVGVRAPALVK
                     EEDWSNNNIEGDKIKLASLAGSTSCSCLDSQLYLDGWEVSAEDAETAEMIAHRTGGMK
                     LSATVIFNPKSPTSLDSAAASQEVPGHSISPLEPRAEGTGDNTHKLSTTATNCLLHSC
                     VCCGSCGDSREDAVECLREKCGPGSVLSASNPSVSLAKGGEKEPERLEEAQPSDVTLP
                     AEDASSRQEPKAPASNKCLAHTSGPQVDTASRLQGESEVKGQPEPEARKQDSEKSPVV
                     SGDSPRGDTAQTEPQHLSGSSSTTGSCSLDSTRLEVTTAVMPVTPMATREKIRSRFHG
                     SHDLIHRLFVCISGVADQLQTNYASDLRSILKTLFEVMATKPETDDKEKLKKVTQSLR
                     SAALEDCALCQETVSSSELAAKTRDGDFEDPPEWVPDEACGVCTSCKAPFTVIRRKHH
                     CRSCGKIFCSRCSSHSAPLPRYGQVKPVRVCTHCYMFHVTPFYSDKTGM"
     exon            215..355
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            356..493
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            494..696
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            697..786
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            787..876
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            877..978
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            979..2283
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            2284..2435
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            2436..2552
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            2553..2657
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            2658..2761
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
     exon            2762..3980
                     /gene="Zfyve28"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacctgcccc gcgcacctgc agccagctgc tcggcgctct gtgcagcgct caggatccgc
       61 ttgctcaggc aggtcccggc cctgcctgcg tgtccgctcc gcgccgcagc cggaccgggg
      121 cgcagcgctg cagagggcga gggccgcccg gagcgtggcc cgagccggcg cggcgatgat
      181 gaacagattc cgaaagtggc tgtataaacc caagaggtca gacccacagc tgctggccca
      241 gttctactat gccgatgagg agctgaacca ggtggctgca gagctagaca gcctggatgg
      301 gcggaaggag ccccagaggt gcacactgct tgtcagccag ttccgctcct gtcaggacaa
      361 tgtgttaaac atcattaatc agatcatgga ggagtgtatc ccccaggacc gagcccctcg
      421 ggatttctgc gtcaagtttc cagaggagat ccggcacgac aacttggctg gccagctgtg
      481 gttcggggct gagtgcctgg cagctggctc catcatcatg aatcgtgagc tggagagcat
      541 ggccatgcgg ccgctggcca aggagctgac gcgcagcctg gaggatgtgc ggggcactct
      601 ccgtgaccag gcactacgag acctcaacac ctacacggag aagatgcggg aggcgctgag
      661 acgctttgat gttctgtttg ccgagtttga actgagctat gtctcagcca tggtgccagt
      721 gaagtccccc agggagtact atgtgcagca ggaggtcatc gtgctgttct gtgagacggt
      781 ggagagagcc ttggagtttg ggtatctgac ccaggacatg attgacgact atgagcctgc
      841 tctcatgttc accattcctc ggctggccat tgtgtgtggc cttgtggtct atgcagatgg
      901 acccctgaac ttggaccgaa aggtggagga catgtctgag ctgttccggc ccttccacac
      961 gttgctgcgg aaaataaggg atctgctgca ggcactgact gaggaggagc tgcacaccct
     1021 ggagcggagc ctctgcgtgt ctcaggatgt ggagcttccc atccgggcag acgcccaggc
     1081 acccagtgcc ctggcaccct ccttttctgc atcccttgcc cccgaggaga cactttccgc
     1141 cagtgccaat aacccagagg aagagctggc ctgctcgatg cagtatgatg accaggagct
     1201 ggaggagctc agccgcatgg tccacagggc cggggatgag atgtcttctc tgctttcacc
     1261 gcccagtgcc tgtcagtccc cagcccatag ggcaggctca gaggctagcc ctcgaggaga
     1321 ggcctctcca gccagagccc agctgaagtc gggcagcgat gaggaggaaa gggtgttctt
     1381 catggatgat gtggaggtga cagagtctcc tgccaggccc gaatccccaa ggagcacatt
     1441 tgagttgacg cagggtaatg tccaacagag aggacaggat ggccagagtg gagaggtggg
     1501 ggttagggca cctgccctgg taaaggagga agactggagc aacaacaaca ttgaaggtga
     1561 caagataaag ctggccagcc tcgcgggctc cacttcctgc agttgcctag actcacagct
     1621 atacctggat ggctgggagg tgagcgcaga ggatgccgag actgcagaaa tgattgcaca
     1681 ccggaccggg ggaatgaagc tgtcggccac agtcatcttc aaccccaagt ctccaacctc
     1741 cttggactca gctgcggcaa gccaagaagt cccgggccat agtatttccc cattggagcc
     1801 cagggccgag gggacagggg acaatacaca caaactcagc actacagcca ccaactgcct
     1861 cctccactcc tgtgtgtgct gtggcagctg tggggacagc agggaggatg ctgtagagtg
     1921 cctacgggag aagtgtggcc caggaagtgt cctcagtgcc tctaaccctt ctgtaagctt
     1981 agccaagggt ggtgaaaaag agcctgagag actagaggag gcccagcctt ctgatgtcac
     2041 cctgcctgca gaagatgcct ccagtaggca ggagcccaaa gcccctgctt ccaacaagtg
     2101 cctggcacac acctcagggc ctcaggtgga cacagcaagc aggttgcaag gagagagtga
     2161 ggtcaaaggc cagccagaac cagaggccag aaagcaggac tctgagaagt ctcctgtggt
     2221 cagtggggac agtccaagag gggacacggc ccagacagaa ccccagcacc tgtcgggctc
     2281 cagctccacg actggttcct gctccttaga cagcaccagg ttggaggtga ccactgcagt
     2341 catgcctgtc acccccatgg ccaccagaga gaagatccgg tccaggttcc atggcagcca
     2401 tgacctgatc caccgcctat ttgtctgcat ttcaggtgta gctgaccagc tgcagacgaa
     2461 ctatgctagc gacctaagaa gtattctcaa aacactgttt gaggtcatgg ccacaaagcc
     2521 agaaacagat gacaaagaga agctaaagaa ggtaacccag agcctgcgga gcgcggcctt
     2581 ggaagactgt gcattgtgcc aggaaactgt gtcatcctca gaactggcag ccaagacccg
     2641 agatggggac tttgaagacc ctcccgagtg ggtgccagat gaggcctgcg gcgtctgcac
     2701 ctcctgtaaa gctcccttca ccgtcatccg caggaagcac cactgtcgca gctgtgggaa
     2761 gatcttctgt tcccgctgct catcacactc agcaccactt ccgcgctatg gccaggtgaa
     2821 gcctgtccgt gtgtgcacgc attgctacat gttccacgtc acgcccttct acagtgacaa
     2881 gacgggcatg tgacgctgtg cctggcatgc cccagctgaa caggctgccc agggtcctgt
     2941 ccagggtctc caggaaggag gtgctgtgcc tgctgtgcgc cctggccagg ccgtgctgcc
     3001 ggagggaggg cctcattgca tctcatcaag cctgggctgc tgcaggcctg cccggcttcc
     3061 aggatgtcca gcctgtctgc tctccctggc ccctccactg tggagacacc agtcctggca
     3121 tgggccaatg agaggtcagc tttattcaga ggagggaccc ggggatggcc agttgctgct
     3181 tccaggtcaa gttacctggc gggcagggtc gaactttctt ctcttgccta tccaatggcc
     3241 ctttgctcca gctgtgcgta ccaaggcagg agagggccaa ttctgtgtgt tctcttctgg
     3301 agccaagaat ctggaagcag aagccagggg gcactaggtc tcaatgccac agcaggactc
     3361 cctgctgttt accacacacc tcactccctg gggctcacac ctgcctcaca ccctcctcag
     3421 ctatacacat ctcatttctt tttgaagggg gaaaaatagg aagcagacac agcggtctcc
     3481 agggagaggg acaggctctt ggcatctata ccattgccac ttgctggctg agcaggggct
     3541 ggccacccac tgatactata ggccaagcga gctctcaggt gtttgggact ggacccatca
     3601 ggcagcttgg ctaacattcc cttcttcctc tgcacccacc gggactctaa cccacttcct
     3661 cagacctcag tgcagcctgg acaggctgag acgcacagac acctcctcag gcttcaatct
     3721 caggcttcac gttgcaatga tgattacagt tttattttta gagagatgac acacctactg
     3781 cttcttttat aggatgaaat ccaatcgctg ttcagcagtg gaatacacac gcacaaaaat
     3841 ggcttctgtg caggggtggg gggaggtaca taacagaggg aatattatgt attgagatta
     3901 tttttatttt ctaaatgctg ttaattcgaa accatttcca taaatctatt taaggattgc
     3961 acatgctctg gcgtcttcta
//
