LOCUS       NM_001130501            4985 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger protein, multitype 2 (Zfpm2), mRNA.
ACCESSION   NM_001130501 XM_001062676 XM_235253
VERSION     NM_001130501.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4985)
  AUTHORS   Klarin,D., Emdin,C.A., Natarajan,P., Conrad,M.F. and Kathiresan,S.
  CONSRTM   INVENT Consortium
  TITLE     Genetic Analysis of Venous Thromboembolism in UK Biobank Identifies
            the ZFPM2 Locus and Implicates Obesity as a Causal Risk Factor
  JOURNAL   Circ Cardiovasc Genet 10 (2) (2017)
   PUBMED   28373160
REFERENCE   2  (bases 1 to 4985)
  AUTHORS   Sheng,W., Chen,L., Wang,H., Ma,X., Ma,D. and Huang,G.
  TITLE     CpG island shore methylation of ZFPM2 is identified in tetralogy of
            fallot samples
  JOURNAL   Pediatr Res 80 (1), 151-158 (2016)
   PUBMED   26959486
REFERENCE   3  (bases 1 to 4985)
  AUTHORS   Kumarasamy,S., Waghulde,H., Gopalakrishnan,K., Mell,B., Morgan,E.
            and Joe,B.
  TITLE     Mutation within the hinge region of the transcription factor Nr2f2
            attenuates salt-sensitive hypertension
  JOURNAL   Nat Commun 6, 6252 (2015)
   PUBMED   25687237
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4985)
  AUTHORS   Garnatz,A.S., Gao,Z., Broman,M., Martens,S., Earley,J.U. and
            Svensson,E.C.
  TITLE     FOG-2 mediated recruitment of the NuRD complex regulates
            cardiomyocyte proliferation during heart development
  JOURNAL   Dev Biol 395 (1), 50-61 (2014)
   PUBMED   25196150
REFERENCE   5  (bases 1 to 4985)
  AUTHORS   Xiang,R., Lei,H., Chen,M., Li,Q., Sun,H., Ai,J., Chen,T., Wang,H.,
            Fang,Y. and Zhou,Q.
  TITLE     The miR-17-92 cluster regulates FOG-2 expression and inhibits
            proliferation of mouse embryonic cardiomyocytes
  JOURNAL   Braz J Med Biol Res 45 (2), 131-138 (2012)
   PUBMED   22267003
REFERENCE   6  (bases 1 to 4985)
  AUTHORS   Svensson,E.C., Huggins,G.S., Lin,H., Clendenin,C., Jiang,F.,
            Tufts,R., Dardik,F.B. and Leiden,J.M.
  TITLE     A syndrome of tricuspid atresia in mice with a targeted mutation of
            the gene encoding Fog-2
  JOURNAL   Nat Genet 25 (3), 353-356 (2000)
   PUBMED   10888889
REFERENCE   7  (bases 1 to 4985)
  AUTHORS   Tevosian,S.G., Deconinck,A.E., Tanaka,M., Schinke,M.,
            Litovsky,S.H., Izumo,S., Fujiwara,Y. and Orkin,S.H.
  TITLE     FOG-2, a cofactor for GATA transcription factors, is essential for
            heart morphogenesis and development of coronary vessels from
            epicardium
  JOURNAL   Cell 101 (7), 729-739 (2000)
   PUBMED   10892744
REFERENCE   8  (bases 1 to 4985)
  AUTHORS   Holmes,M., Turner,J., Fox,A., Chisholm,O., Crossley,M. and Chong,B.
  TITLE     hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2
            and modulates GATA-mediated activation
  JOURNAL   J Biol Chem 274 (33), 23491-23498 (1999)
   PUBMED   10438528
REFERENCE   9  (bases 1 to 4985)
  AUTHORS   Morsli,H., Tuorto,F., Choo,D., Postiglione,M.P., Simeone,A. and
            Wu,D.K.
  TITLE     Otx1 and Otx2 activities are required for the normal development of
            the mouse inner ear
  JOURNAL   Development 126 (11), 2335-2343 (1999)
   PUBMED   10225993
REFERENCE   10 (bases 1 to 4985)
  AUTHORS   Svensson,E.C., Tufts,R.L., Polk,C.E. and Leiden,J.M.
  TITLE     Molecular cloning of FOG-2: a modulator of transcription factor
            GATA-4 in cardiomyocytes
  JOURNAL   Proc Natl Acad Sci U S A 96 (3), 956-961 (1999)
   PUBMED   9927675
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473950.2.
            
            [WARNING] On Nov 14, 2024 this sequence was replaced by
            NM_001130501.2.
            
            On or before Jul 27, 2008 this sequence version replaced
            XM_235253.4, XM_001062676.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132269,
                              SAMD00132290 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..4985
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q31"
     gene            1..4985
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /note="zinc finger protein, multitype 2"
                     /db_xref="GeneID:314930"
                     /db_xref="RGD:1306021"
     exon            1..552
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     CDS             513..3968
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /codon_start=1
                     /product="zinc finger protein ZFPM2"
                     /protein_id="NP_001123973.1"
                     /db_xref="GeneID:314930"
                     /db_xref="RGD:1306021"
                     /translation="MSRRKQSKPRQIKRPLEDAIEDEEEECPVEEADVIAKGDFPLEE
                     SFPTGFESENLSCEEVEFFCNKGDDEGIQEPAESDGDSHSDKPGQPGVETDDWDGPGE
                     LEVFQRDGERKIQSRQQLPVGTTWGPFAGKMDLNNNSLKTKAQVSMVLTAGPKWLLDV
                     TWQGVEDSKNNCIVYSKGGQLWCTTTKAISEGEELIAFVVDFDSRLQTASQMTLTEGM
                     YPARLLDSIQLLPQQAAMASILPTAIVNKDIFPCKSCGIWYRSERNLQAHLMYYCSGR
                     QREAAPVSEENEDSTHQISSLCPFPQCTKSFSNARALEMHLTSHSGVKMEEFLPPGAS
                     LKCTVCSYTADSVINFHQHLFSHLTQAAFRCNHCHFGFQTQRELLQHQELHVPGGKLP
                     RESDMEHSPSGTEDSLQPATDLLARSDLSQSQKAMPTKDASSDTELDKCEKKTQLFLT
                     NQRPEMQPAANKQNFSYTKIKSEPSSPRLASSPVQPNLGPSFPVGPFLSQFAFPQDIT
                     MVPQASEILAKMSELVHRRLRHGSSSYPPVIYSPLMPKGATCFECNITFNNLDNYLVH
                     KKHYCSSRWQQMAKSPEFPSVSEKIPEALSPNTGQTSINLLNPAAHPPDPENPLLQTS
                     CINSSTVLDLIGPNGKGHEKDFSTQAKKLPTSNNNDDKINGKPVDVKNPSGPLVDGES
                     DPNKTTCEACNITFSRHETYMVHKQYYCATRHDPPLKRSASNKVPAMQRTMRTRKRRK
                     MYEMCLPEQEQRPPLVQQRFLDVANLSNPCSSTQEPTEGLGECYHPRCDIFPGIVSKH
                     LETSLAINKCVPVPKCDTTHSSVSCLEMDVPIDLSKKCLSQSERTTASPKRLLDYHEC
                     TVCKISFNKVENYLAHKQNFCPVTAHQRNDLGQLDGKVFPNPESERNSPEVSFERNMI
                     KCEKNGNPKQPSPNGNLFSSHLATLQGLKVFSEAAQLIATKEENKHLFLPQCLYPGAI
                     KKTKGADQLSPYYGIKPSDYIAGSLVIHNTDVEQNTNTENESPKGQASSNGCAVPKKD
                     SLPLLPKNRGMVIVNGGLKQDERPTANPQQENISQNAQHEDGHKSPSWISENPLAANE
                     NVSPGIPCAEEQLSSIAKGVNGSTQAPSSGKYCRLCDIQFNNLSNFITHKKFYCSSHA
                     AEHVK"
     exon            553..711
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            712..813
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            814..932
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1044
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1045..1251
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1252..1476
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
     exon            1477..4985
                     /gene="Zfpm2"
                     /gene_synonym="FOG-2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcagtgcgag cgcggcgcgg cccggagcgg cagcggcggc gcctgagtct ctgcccggca
       61 gccggggaca cggggagcga gtgcgcgcct cctcctgcac cctccgcccc tcgcagcccc
      121 ggtccccctg cgcgctctcc ttccctccct ccttctcttc cttctcttac cccaccaccc
      181 ccttcttccc cttttctctc tgcctggccg atcgctccta gattcccatc ctccccccaa
      241 aagccccatc gctctccccg tcgccccctc ccctcttctc tgtcacactc tctctggccc
      301 ttcgctcggc ctctcatttg cttgctcatc tccaaacgtg gatccgcggc tcccggagga
      361 gcctagctcc gggatcccgc gcgcacggag cacctggagt ccggccggcg gcggcccgag
      421 cctggccaga ggcagaggca gcgacaaccc agggaacggt agcagggacc gcggacaccg
      481 caggaacccc agcggcagcg gccgcggccg agatgtcccg gcgaaagcag agtaaacccc
      541 ggcagatcaa acggccgctg gaagatgcca tcgaagatga ggaagaagag tgtcccgtag
      601 aggaggctga cgtcatcgcg aaaggagact ttccattgga ggaaagcttc cccacaggct
      661 tcgagtcaga aaatctgagc tgtgaagaag tggagttctt ttgtaacaaa ggtgatgacg
      721 aaggaatcca ggagccagca gaatcagatg gggacagcca ttcagacaaa ccggggcagc
      781 ctggagtaga gacagatgac tgggatggac caggagagct agaagtattt cagagagatg
      841 gggaaaggaa gattcagagt cggcagcagc ttccggtggg aacaacctgg ggccctttcg
      901 ctgggaagat ggacttgaac aataattcct tgaagacgaa ggctcaggtc tccatggtgc
      961 tgactgctgg tcccaagtgg cttctggatg tgacttggca aggagtggag gacagcaaaa
     1021 acaactgcat tgtgtacagc aaagggggtc agctttggtg caccacgacg aaggccatct
     1081 cggagggtga agaactaatt gcctttgtgg tggactttga ctcaaggcta caaactgcta
     1141 gccagatgac tctcacagaa gggatgtacc cggcccgcct gctggactca attcagctgc
     1201 ttcctcagca agctgccatg gcttctattt tgcctacagc tattgtcaat aaggatatat
     1261 tcccttgcaa gtcctgtggc atttggtacc ggagcgagcg gaacctgcaa gcccatttga
     1321 tgtactactg tagtgggagg caaagagaag ctgctccagt gtctgaagaa aatgaagaca
     1381 gtacgcatca gatttccagc ctgtgcccct tcccacaatg caccaagagc ttttccaatg
     1441 cccgagctct agaaatgcac ctgacttcac acagtggagt gaaaatggaa gagttcctgc
     1501 ctcccggggc gagtttgaaa tgcacggtgt gtagctacac tgctgattcc gtgatcaact
     1561 tccaccaaca cctgttctcg catctcactc aagctgcctt ccgttgcaac cactgccatt
     1621 ttggcttcca gacccaaagg gagttactgc agcaccagga gctccatgtc cccggtggca
     1681 aacttcccag agaaagcgac atggagcact ctccaagtgg aacagaagac agcttacagc
     1741 cagccacaga cttgttggcc agaagtgacc tctcccagag ccaaaaggcc atgccgacta
     1801 aagatgcaag ctcagacaca gagctggaca agtgtgagaa aaagactcaa ctctttctca
     1861 ccaatcagag accagagatg cagcctgcgg caaacaagca gaacttctct tacacaaaaa
     1921 taaagtctga gccttccagc cccagacttg cctcatctcc agtgcaaccc aacctagggc
     1981 cctctttccc tgtgggacct ttcctgtctc agtttgcttt cccccaagat atcaccatgg
     2041 tccctcaagc ttcagagatc ttagccaaga tgtccgagct ggtgcaccga cgcctgaggc
     2101 acgggagtag tagctaccct cctgtaattt acagcccttt gatgcccaaa ggggctacat
     2161 gctttgagtg taacataacg ttcaataatc tggataacta tctagttcat aaaaaacact
     2221 actgcagcag ccgatggcag cagatggcca aatcccctga gtttccaagt gtttctgaaa
     2281 agataccgga agctctgagt cctaacactg gccagacttc cataaacctt ctcaacccgg
     2341 cggctcatcc accggacccg gagaatccac ttcttcaaac atcctgcatc aactcttcca
     2401 cggttttaga tttgattggg ccaaacggaa agggccatga gaaggacttt tccactcaag
     2461 ccaaaaagtt gcccacctcc aacaacaatg acgacaaaat aaatggaaag cccgttgatg
     2521 tgaaaaatcc cagcggcccc ttagtggatg gggaaagtga cccaaataag actacctgtg
     2581 aagcttgtaa catcaccttc agcaggcatg aaacctatat ggtccacaaa cagtattact
     2641 gtgcaacgcg ccatgaccct ccgctaaaga ggtctgcttc caacaaagtg ccggccatgc
     2701 agagaaccat gcgcacacgc aagcgaagaa agatgtacga aatgtgccta cccgagcaag
     2761 agcaacggcc acccctagtt cagcagagat ttcttgatgt agccaacctc agcaatcctt
     2821 gtagctccac tcaagagccc actgaagggc taggagaatg ctaccacccg agatgcgaca
     2881 tcttcccagg aattgtctca aagcacttgg aaacatcgtt ggccataaac aaatgtgttc
     2941 cggttcccaa atgtgataca actcattcca gtgtttcctg cctggagatg gacgtcccca
     3001 tagatctcag caaaaagtgt ttatcgcagt ctgagcggac gacagcatct cctaaaaggc
     3061 tactagacta ccacgagtgc accgtgtgca agatcagctt caataaggtc gagaactacc
     3121 tggcccacaa gcagaatttc tgccctgtca ctgcacatca acgcaacgac ctaggtcagc
     3181 ttgatggcaa agtgtttccg aatccagaaa gtgaacggaa cagcccggaa gtcagctttg
     3241 aaagaaacat gatcaaatgt gagaagaatg ggaatccgaa gcagccttct cccaacggaa
     3301 acttgttttc atcccatttg gcaaccttgc aaggcctgaa agtcttcagt gaggcggctc
     3361 agctcattgc tacaaaagaa gaaaacaaac atttgtttct tccccaatgc ctttaccctg
     3421 gagcaataaa gaagacgaaa ggagccgacc agctttctcc atactatggc ataaagccaa
     3481 gcgattatat cgccggttct cttgtcatcc acaacaccga cgtcgaacag aacacaaaca
     3541 cagaaaacga gtctcctaaa ggccaggcct cctcaaatgg gtgtgcggta cccaagaaag
     3601 attctctgcc attgttgccc aaaaacagag gcatggtcat agtgaatggt ggactgaagc
     3661 aagatgaaag gcctaccgca aacccacagc aagagaacat ttcccagaat gcccagcacg
     3721 aagacggcca caaatcccct tcgtggatct ctgagaaccc gttagctgca aatgagaatg
     3781 tctccccagg aattccctgc gcagaagaac agttgtctag catagcaaaa ggtgtgaatg
     3841 gctctaccca ggcccccagc agtgggaaat actgccggct atgcgatatc cagttcaata
     3901 acctttcaaa ctttataact cacaagaagt tttattgctc atcacatgca gcagaacatg
     3961 tcaaatgaac taactgagta actaaagaaa gcagtcacct ttggtaccgt gtttagtatg
     4021 ttcttctaaa cagtccagaa aacaaagaag ctgtttgaat tacatctgcc gatcaggaga
     4081 taattcataa tggctgagtt gaagacttgg tgtaatttca ttacagacca ttagtaaagt
     4141 gtattattgg tgccattttc agaaaaaaaa ttaatttatt ttaccagcag tattcatagc
     4201 tgtggttatg ttatttttat ttaaaaactt tatattaaag tcatttgtaa tgttattgta
     4261 tagttattgt gtagcacata tggtttgcac tgtatagtag cttttaaaga aaatagtcac
     4321 aaacaataca gaagagcatt ttagaaatag cttcaaaagc acttgtgtat cctgattttt
     4381 tttcttatat gctgttgcag atatacgtat atgctaaaat ataacctgca aacatgttct
     4441 aaatacacat gctgtaagtt cgccttaagg tttcgattct cggctaatca ggccccagtt
     4501 gcactttata ttttagcaaa tacagtccct tagtctctag gctttgcatt tgtatgtagc
     4561 cgtatatttc cgtccatttc ctcagactga aacatgtatg ttaaacgaag atggcaattt
     4621 tttcttgtat agtacttgta ttttctttcg ccgatgcagc cctgtcccaa tttttaaacc
     4681 ttggctgtta aatgcaatac tttataaaga atgaacaaaa ttactggaag cagtattgta
     4741 aggatcggag tagtggtaat cagttttatc tttcgaaagg cacagtctaa atcgaacccc
     4801 taaactcaat gctgcaagta tgaatttaat tcatatataa gatctattta aatataagag
     4861 tagcaatact gcacctggtg atcacaaaga taatgttcta cttctgatag aaaataattt
     4921 ctcaacaaat gttgttacta tgcatgtaca tggatggaat aaaattccaa attgttggag
     4981 atgtt
//
