LOCUS       NM_001100852            3691 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus zinc finger protein 746 (Zfp746), mRNA.
ACCESSION   NM_001100852 XM_001053818 XM_231752
VERSION     NM_001100852.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3691)
  AUTHORS   Shin,J.H., Ko,H.S., Kang,H., Lee,Y., Lee,Y.I., Pletinkova,O.,
            Troconso,J.C., Dawson,V.L. and Dawson,T.M.
  TITLE     PARIS (ZNF746) repression of PGC-1alpha contributes to
            neurodegeneration in Parkinson's disease
  JOURNAL   Cell 144 (5), 689-702 (2011)
   PUBMED   21376232
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On or before Jul 23, 2009 this sequence version replaced
            XM_231752.4, XM_001053818.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.22761.1,
                                           SRR26643292.17704.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-279               JAXUCZ010000004.1  78409554-78409832   c
            280-579             JAXUCZ010000004.1  78406638-78406937   c
            580-661             JAXUCZ010000004.1  78406427-78406508   c
            662-775             JAXUCZ010000004.1  78405512-78405625   c
            776-967             JAXUCZ010000004.1  78390724-78390915   c
            968-1093            JAXUCZ010000004.1  78389995-78390120   c
            1094-3691           JAXUCZ010000004.1  78385945-78388542   c
FEATURES             Location/Qualifiers
     source          1..3691
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..3691
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /note="zinc finger protein 746"
                     /db_xref="GeneID:312303"
                     /db_xref="RGD:1306209"
     exon            1..279
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     CDS             256..2208
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /codon_start=1
                     /product="zinc finger protein 746"
                     /protein_id="NP_001094322.1"
                     /db_xref="GeneID:312303"
                     /db_xref="RGD:1306209"
                     /translation="MAEAAAAPISPWTMAATIQAMERKIESQAARLLSLEGRTGMAEK
                     KLADCEKTAVEFSNQLEGKWAVLGTLLQEYGLLQRRLENVENLLRNRNFWILRLPPGS
                     KGEVPKEWGKLEDWQKELYKHVMRGNYETLVSLDYAISKPEVLSQIEQGKEPCTWRRT
                     GPKVPEVPVDPSPGSGAPVPAPDLLMQIKQEGELQLQEQQALGVEAWAAGQPDIGEEP
                     WGLSQLDSGAGDISTDATSGVHSNFSTTIPPTSWQADLPPHHPSSACSDGTLKLNTAA
                     STEADVKIVIKTEVQEEEVVATPVHPTDLEAHGTLFAPGQATRFFPSPVQEGAWESQG
                     SSFPSQDPVLGLREPTRPERDIGELSPAIAQEEAPAGDWLFGGVRWGWNFRCKPPVSL
                     NPRTVPEGLPFSSPDNGEAILDPSQAPRPFNDPCKYPGRTKGFGHKPGLKKHPAAPPG
                     GRPFTCATCGKSFQLQVSLSAHQRSCGLSDGAGTGAASTATGGGGGGGGGGSSAGGSS
                     ARDSSALRCGECGRCFTRPAHLIRHRMLHTGERPFPCTECEKRFTERSKLIDHYRTHT
                     GVRPFTCTVCGKSFIRKDHLRKHQRNHPAVAKAPAHGQPLPPLPAPPDPFKSPAAKGP
                     MASTDLVTDWTCGLSVLGPNDGGGDL"
     exon            280..579
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     exon            580..661
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     exon            662..775
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     exon            776..967
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     exon            968..1093
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
     exon            1094..3691
                     /gene="Zfp746"
                     /gene_synonym="RGD1306209; Znf746"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggaagcctc acgggccttc gtcggcctgg ccgcggcgcc ggctcccagg atgcagtgtg
       61 gagcggccgg gcgctgacgg cggcggtgcg gctgcgggcg gagcggcagc aggccggcct
      121 gcgaggagcg cggcggggaa ggtagcggca ggcccgggcg gcgctgccgg cggagaggac
      181 ccggcggcca ggcctgcgtg gggccgcgcg ccgcggcgtc gacttcctcc gctcccggca
      241 ggacagcgca gggccatggc cgaggcggcc gcggctccga tttctccatg gacaatggca
      301 gctacaattc aggctatgga aaggaaaatt gaatcacagg ctgctcgact actttctcta
      361 gaaggtcgaa ctgggatggc ggagaagaag ctggctgact gtgagaagac agctgtggag
      421 ttcagcaacc agctggaggg caagtgggcc gtgctgggaa ccctgctgca ggagtacggc
      481 ctgctgcagc ggcggctgga gaatgtggag aatctgctac gcaaccgaaa cttctggatc
      541 ctgcggctgc cccctggcag caagggcgag gtccccaagg agtggggcaa gctggaagac
      601 tggcagaagg agctctacaa gcatgtgatg aggggcaact acgagacact ggtttccctg
      661 gactatgcca tctccaaacc cgaggtcctc tcccagattg aacaaggcaa ggagccatgc
      721 acctggcgtc gcactggccc caaggtcccg gaggttcctg tggacccaag tccaggttct
      781 ggagcaccag ttcctgcccc tgacctcctg atgcaaatca agcaagaggg ggagctccaa
      841 ctacaggagc agcaggctct gggtgtggaa gcctgggcag ctggacaacc agatattggg
      901 gaagagccgt ggggcctcag ccagttggac tctggagcag gagacatctc cacagatgct
      961 acctctggtg tccattccaa cttttcaacc accatcccac ccacttcctg gcaagcagac
     1021 ctccctcccc accacccctc ttcagcatgc tcagatggga cattgaagct caacacagca
     1081 gcatccacag aagcagatgt aaaaattgtt atcaaaacag aagtccaaga agaggaggtg
     1141 gtggctacac ctgtgcatcc caccgacctg gaggctcatg ggactttgtt tgcaccaggc
     1201 caagccacaa gattcttccc cagccctgtc caggaaggag cctgggagag tcaaggcagt
     1261 tccttcccca gccaggaccc agtgctgggc ctgcgggagc ccactcggcc agagagggac
     1321 attggtgagc tcagtcctgc catagcacag gaggaggctc ctgccgggga ttggctcttt
     1381 ggaggagtca ggtggggctg gaatttccgg tgtaaacctc cagtgagcct gaacccaagg
     1441 acggtgcccg aggggctccc tttctcatct ccagacaatg gagaggccat cttggacccc
     1501 agtcaggccc caagaccctt caatgatccc tgcaaatacc ccggccggac aaaaggcttt
     1561 ggccacaaac cggggctgaa gaagcaccca gcagcaccac ccggaggccg gcccttcacc
     1621 tgtgccacct gcggaaagag cttccagctg caggtgagcc tcagtgctca ccagcgcagc
     1681 tgcggactgt cggacggggc gggtaccggg gcagcttcca ccgctacagg aggcggaggt
     1741 gggggcgggg gcggaggcag cagcgcaggt ggaagcagtg cacgggacag cagcgctctg
     1801 aggtgtgggg agtgtggccg ctgcttcaca cgccctgcac acctcatccg ccaccgcatg
     1861 ctacacactg gtgagaggcc cttcccctgc accgagtgcg agaagcgctt cacagagcgt
     1921 tccaagctca tcgaccacta ccgaacgcac acaggcgtgc ggcccttcac ctgcacagtg
     1981 tgtggaaaga gcttcatccg caaggaccac ctccgcaagc accagcgcaa ccacccggca
     2041 gtggctaagg cacctgcaca cggtcagccg ctcccaccac tgccggctcc tcctgatccc
     2101 ttcaagagcc ccgcagccaa aggacccatg gcatccacag accttgtgac tgactggact
     2161 tgtggcctaa gtgtcctggg acccaatgat ggtggtggag acctgtgagg gccccaaccc
     2221 tcctgtggcc cctgcaagcc acgaatgtac agccctgaat gcagatagca ggatggcctg
     2281 aaagctcaga agcagaatgg gggacatggc agaaaaccaa atcccatgtt gctgaactga
     2341 tcactggaaa gaaggactat caacgcagcc tccgcctgaa cgtagagttc cgactgtgaa
     2401 actgaacacc ttaatggatc ttaagtaatt taattaccct tttttttttt tttttgtttt
     2461 gttttttctc taattcttga gggaaaagct ggaaaaatgg tagcaacgac cagtttttga
     2521 ggtgtggctt tgagaggtgt gtgctcacct tgtcttagca gtgttggaaa gatggtcagt
     2581 gggagaagca ggcaagggca ctcccagccg tggaccacac agtcctgggc aggttgagtt
     2641 ccagtcctgt ccaggcatgc tggggcctag actgacaggt tccactcagc agtagggacc
     2701 ctactagaag cagcccttct cttctgaaaa gaccctttaa gccaaggcct gacttttcct
     2761 gttttgagcc atctgtgata cctgtccaag gtggtaacat ccactgtagt agtgacttct
     2821 gggccaggct aagaagaatc atatggagct gtagtagtgt ttgatctcaa gggtgttttg
     2881 ccttcgaaca tgaagtcaca gaaagccagg gccacccatc ttgggctacc tccattaccc
     2941 atagatgctt cagttggctg cccattgtgt agtatgttca ttttcaaaat ggactcaccg
     3001 gttccacctc acatgtcatt ccaccattaa ccatgacttt gcaaagcagg tagacaggca
     3061 gttctttcta cagaagagga ataaagggct cagaggggac agagcctctc catgagtact
     3121 gtgtgttcta ggagctaagg tgagcagcag tgatactggg tcctagaata gtggaaaggt
     3181 tttgagatct tgccctctta aaagatttgt cccacacgca tggatcagat agatcaagac
     3241 agaactcctg cctcagcagc tcgagctgga cagtccccgg tgtgtgtgct tgcacatcat
     3301 agacatgcag gaggcagttg gattgccagc taactgggta aatggctctc aggcctgcct
     3361 gcctggagta tcttcacagt ggaattagag ctaggtccaa gtttctgtct taacagtgct
     3421 gtccccatca cacatagcca ttcccatttt gttaaagcag ccactggtcc tcttgcccaa
     3481 atgggtaatg attccctgaa gagggcagag accatggtgc ccattcagct ccttcctgca
     3541 tacttttatt agaaatagac tagttaagaa aattgtttct atgtactgta tattttgtac
     3601 ctgtttacac ttctaatatt gatataactg atattttgaa aaacagatga acagaaaaca
     3661 tcctgttaaa ataaaatcta accagcacca a
//
