LOCUS       NM_001105770            3275 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger protein 598 (Zfp598), mRNA.
ACCESSION   NM_001105770 XM_001056388 XM_213230
VERSION     NM_001105770.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3275)
  AUTHORS   Sundaramoorthy,E., Leonard,M., Mak,R., Liao,J., Fulzele,A. and
            Bennett,E.J.
  TITLE     ZNF598 and RACK1 Regulate Mammalian Ribosome-Associated Quality
            Control Function by Mediating Regulatory 40S Ribosomal
            Ubiquitylation
  JOURNAL   Mol Cell 65 (4), 751-760 (2017)
   PUBMED   28132843
REFERENCE   2  (bases 1 to 3275)
  AUTHORS   Juszkiewicz,S. and Hegde,R.S.
  TITLE     Initiation of Quality Control during Poly(A) Translation Requires
            Site-Specific Ribosome Ubiquitination
  JOURNAL   Mol Cell 65 (4), 743-750 (2017)
   PUBMED   28065601
REFERENCE   3  (bases 1 to 3275)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   4  (bases 1 to 3275)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   5  (bases 1 to 3275)
  AUTHORS   Fu,X., Zang,K., Zhou,Z., Reichardt,L.F. and Xu,B.
  TITLE     Retrograde neurotrophic signaling requires a protein interacting
            with receptor tyrosine kinases via C2H2 zinc fingers
  JOURNAL   Mol Biol Cell 21 (1), 36-49 (2010)
   PUBMED   19864463
  REMARK    GeneRIF: NTRAP regulates retrograde neurotrophic signaling by
            controlling the formation of signaling endosomes.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 3, 2007 this sequence version replaced
            XM_001056388.1, XM_213230.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3275
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..3275
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /note="zinc finger protein 598"
                     /db_xref="GeneID:287119"
                     /db_xref="RGD:1304900"
     exon            1..225
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     CDS             13..2721
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /codon_start=1
                     /product="zinc finger protein 598"
                     /protein_id="NP_001099240.1"
                     /db_xref="GeneID:287119"
                     /db_xref="RGD:1304900"
                     /translation="MAAAGAEGRRAALEAVAAPERGGGSCVLCCGDLEATALGRCDHP
                     VCYRCSTKMRVLCEQRYCAVCREELRQVVFGKKLPAFAMIPIHQLQHEKKYDIYFADG
                     KVFALYRQLLQHECPRCPHLPPFSLFGDLEQHMRKQHELFCCKLCLKHLKIFTHERKW
                     YSRKDLARHRMQGDPDDTSHRGHPLCKFCDERYLDNDELLKHLRRDHYFCHFCDADGA
                     QDYYSDYAYLREHFREKHFLCEEGRCSTEQFTHAFRTEIDLKAHKTACHSRSRAEARQ
                     NRQIDLQFSFAPRHSRRSEGVVSGEDYEEVDRYNRQGRAGRASGRGAQQNRRGSWREE
                     EDREVAAAIRASVAAQQQEETQRVEDREEGSRPKKEEAAVRVPEESRGHRRLPRAQGE
                     GTGSKETSTNGPVSQEAFSATGPGPVVAPSNTLPPPNPKLKDEDFPSLCVSTSCCTAV
                     TPSSVGLALAYPAPPRGKNTFQEEDFPALVSSAPKPSSAPSSLISAWNSSCSKKGNPP
                     TPGAQAVVGSSQPSRKAGKGSRGGRKGGPAPVDEDSGGLTVQELRSVPTTVAVSSLLA
                     PVANQNSAKVGKKKKMGSEKPGATSSPLLPPDHTPKPSGAEQVPEAPLSKAEVPVTIV
                     VNGHSEGSALAWSIPKEPPGLPRPLGPLPCPIPQEDFPALGGPCPPRMPPPPGFSTVV
                     LLKGTPPPPPPPPGLVPPISKPPPGFSSFLPSSHSTCVPSTTTITTTTTNMKAPRLAP
                     TAGAYLVPENFRERNLQLIQSIKDFLQSDEACFSKFKSHSGEFRQGMISAAQYYKSCR
                     DLLGENFQKIFSELLALLPDTAKQQELLSAHTDFCSRERPPSSKSKKNKKNVWQTSTQ
                     QLGLDCCVCPTCQQVLAHGDVSSHQALHAARDDDFPSLQAIARIIT"
     exon            226..338
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            339..468
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            469..680
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            681..898
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            899..1007
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            1008..1195
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            1196..1280
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            1281..2041
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            2042..2216
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            2217..2367
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
     exon            2368..3275
                     /gene="Zfp598"
                     /gene_synonym="Ntrap; Znf598"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cggagcccgg ccatggcggc ggcgggcgcc gaggggcggc gcgcggctct ggaggcggtg
       61 gcagcgccgg agcgaggcgg cgggagctgc gtgctgtgct gcggtgacct ggaggctacg
      121 gcgctgggtc gctgcgatca cccggtgtgc taccggtgct ctaccaagat gcgggtgctg
      181 tgcgagcagc gctactgcgc cgtatgccgc gaggagctac gccaggtggt ctttgggaag
      241 aaactccctg cctttgctat gatccccatt catcagctcc aacatgagaa gaaatatgac
      301 atctattttg cagatggaaa ggtgtttgcg ttgtacaggc agctgctaca gcacgagtgc
      361 ccacggtgcc ctcacctgcc acccttcagc ctctttgggg acttggagca gcacatgcgg
      421 aagcagcacg agctcttctg ctgcaagttg tgcctcaagc acctcaagat cttcacccat
      481 gagcgcaagt ggtactcacg caaggacctg gctcgacacc gtatgcaggg tgaccctgat
      541 gacacatccc atcggggaca cccactctgt aagttctgtg acgagcgcta cctggacaat
      601 gatgagctgc tcaagcacct gcgtcgcgac cactacttct gccacttctg tgatgccgat
      661 ggggcccagg actactatag cgattatgcg tacctgcgtg agcacttccg ggagaagcac
      721 ttcctatgtg aggagggccg ttgcagcact gagcagttca cccatgcctt ccgcactgag
      781 attgacctca aggctcacaa aacagcttgc cacagccgca gccgggccga ggcacgccag
      841 aaccgtcaga ttgaccttca atttagcttt gcaccacggc actcacgccg gagtgaggga
      901 gtcgtcagtg gtgaggacta cgaggaggtg gacaggtaca accgccaggg ccgagctggc
      961 cgggccagcg ggcgtggagc ccagcagaac cgccggggaa gctggaggga agaagaagac
     1021 cgagaagtag cagccgctat cagggcctct gtggctgccc agcaacaaga ggagactcag
     1081 agggtcgagg accgggagga gggtagcagg cccaagaaag aggaagcagc agtcagggtg
     1141 cccgaggaat cccgtggcca ccggcgtctg cctcgggctc agggtgaagg cacaggctcc
     1201 aaggaaacct caacaaacgg tcctgtaagc caagaagcct tctcagccac aggcccaggc
     1261 ccagtggttg ccccctcaaa taccctccca ccacccaacc ccaagctcaa ggatgaagac
     1321 ttccccagcc tctgtgtctc cacctcctgc tgcacagcgg ttaccccaag ctctgtaggc
     1381 ttggcactgg cttatcctgc tcctcccagg ggcaagaaca ccttccagga agaggatttc
     1441 cctgctctgg tttcctccgc acccaagccc agcagtgccc catccagcct catctcagct
     1501 tggaatagca gctgcagcaa gaaagggaac ccacccaccc caggggccca ggctgtagtt
     1561 ggtagcagcc agccttcccg gaaggcaggg aaagggagca ggggtggcag gaagggtggt
     1621 ccagccccag tggatgagga tagtggtggc ctcactgtgc aggagctgcg gagtgtgccc
     1681 accacagtgg ctgtctcttc tttgctggca ccagttgcca accagaattc agccaaggtt
     1741 ggcaagaaga agaagatggg ctctgagaag cctggggcca catcatcccc actgttgccc
     1801 cctgatcata ccccaaaacc ttctggggct gagcaggtcc ccgaagcccc tttgagcaaa
     1861 gctgaagtgc cagtaaccat cgttgtcaat ggacattcag agggctcagc cctggcttgg
     1921 agtatcccaa aggaacctcc aggccttcca aggcccctag gtcccctccc ctgccccata
     1981 ccacaggaag actttccagc tctcggaggc ccttgtccac ccaggatgcc tcctccccca
     2041 ggcttcagca ccgtggtgct cttgaagggc acaccacctc cacccccacc cccaccaggc
     2101 ctggtgcctc ccatcagcaa gccaccccct ggattctcta gtttcttgcc cagctcccac
     2161 tcaacctgtg ttcctagtac taccaccatc accactacca ccaccaacat gaaagcaccc
     2221 cggctagcac ccacagcagg agcctactta gttcctgaga atttccggga gagaaaccta
     2281 cagcttatcc agtctatcaa ggactttcta caaagcgatg aggcctgctt cagcaagttt
     2341 aaaagccatt caggagagtt cagacagggg atgatctctg cagctcagta ctacaagagc
     2401 tgcagggacc tgcttggaga gaacttccag aagatcttca gtgagctgct ggcactcctg
     2461 ccagacacag ccaaacagca ggaactgctg tctgcacaca ctgacttctg cagccgtgag
     2521 aggcctccca gctccaaatc taagaaaaac aagaagaatg tgtggcagac cagcacccag
     2581 cagttgggcc tggactgctg tgtgtgcccc acctgccagc aggtactggc acacggcgac
     2641 gtcagcagcc accaggcact gcacgctgcc cgggacgatg acttcccctc ccttcaagcc
     2701 attgccagga tcatcacgta gctcctgctg gtgagagcaa gagctgtcac accctagcgc
     2761 ctcctttctc cttccttcct cttcccagct gcttggcagc taggtagggc cctgggaagg
     2821 ttgaggctcg ggcctcctgg ttagccaggc ctgccaggtg gacgtcagga aaggtctgcc
     2881 ctgtgcacca tcatgcataa gttctgtccc atgcttggct gagggtcagt cttggtttgt
     2941 gatcttatgg ttttggagtg tgccagggga gggaaaggct aggatgctag gacctgagct
     3001 agaagcctca gtggcctgaa gagcgttctc ctgtgtcgag cctatagccc cagagctgac
     3061 agcttcgggt ccactggtgc tggagtcaga tgtcaagtgt gtcgtgtaaa caattggctg
     3121 tttcatagag aatgttccag attaaaaaca gacacaaaat tgtgctactt gaagttcaat
     3181 ctttttacaa gacaagttaa atctaagatc tcaagttgcc tctgacattt tataaaagac
     3241 agtttatctt caaataaatt tattttgcag tactg
//
