LOCUS       NP_001012110             541 aa            linear   ROD 28-MAR-2024
DEFINITION  zinc finger protein 513 [Rattus norvegicus].
ACCESSION   NP_001012110 XP_233931
VERSION     NP_001012110.1
DBSOURCE    REFSEQ: accession NM_001012110.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 541)
  AUTHORS   Li,L., Nakaya,N., Chavali,V.R., Ma,Z., Jiao,X., Sieving,P.A.,
            Riazuddin,S., Tomarev,S.I., Ayyagari,R., Riazuddin,S.A. and
            Hejtmancik,J.F.
  TITLE     A mutation in ZNF513, a putative regulator of photoreceptor
            development, causes autosomal-recessive retinitis pigmentosa
  JOURNAL   Am J Hum Genet 87 (3), 400-409 (2010)
   PUBMED   20797688
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Feb 11, 2005 this sequence version replaced XP_233931.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC089202.1, SRR23984936.448551.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..541
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q14"
     Protein         1..541
                     /product="zinc finger protein 513"
                     /calculated_mol_wt=57960
     Region          1..120
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FWU5.1)"
     Site            85
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (Q5FWU5.1)"
     Site            96
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q6PD29; propagated from
                     UniProtKB/Swiss-Prot (Q5FWU5.1)"
     Region          152..172
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(157,159,161,163..164,167..168,171,185,187,191..192,
                     195..196,199,213,215,217,219..220,223..224,227)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          176..>228
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          180..200
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          192..217
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          208..228
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          362..382
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(367,369,371,373..374,377..378,381,395,397,401..402,
                     405..406,409,423,425,427,429..430,433..434,437)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          374..399
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          390..410
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          402..425
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          414..>487
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          418..438
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          446..466
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          474..493
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          492..541
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q5FWU5.1)"
     CDS             1..541
                     /gene="Zfp513"
                     /gene_synonym="Znf513"
                     /coded_by="NM_001012110.2:208..1833"
                     /db_xref="GeneID:313913"
                     /db_xref="RGD:1310456"
ORIGIN      
        1 mprrkqshpq pvkcegvkvd tedsfdegpg alvlesdlll gqdlefeeee eeeegdghnd
       61 qlmgferdse gdsqgarpgl pyglsddesg ggralsaese veepargpge argerpgpac
      121 qlcggptgeg pccgaggpgg gpplpprlly scrlcafvsh ysshlkrhmq thsgekpfrc
      181 grcpyasaql vnltrhtrth tgekpyrcph cpfacsslgn lrrhqrthtg pptppcptcg
      241 frccaprptr ppspteqegt mprrsedali lpdlslhvpp ggtsflpdcg qlrgegeglc
      301 gtgseplpel lfpwtcrgcg qeleegegsr lgtamcgrcm rgesggggsg gpqgpsdkgf
      361 acslcpfath ypnhlarhmk thsgekpfrc arcpyasahl dnlkrhqrvh tgekpykcpl
      421 cpyacgnlan lkrhgrihsg dkpfrcslcn yscnqsmnlk rhmlrhtgek pfrcatcayt
      481 tghwdnykrh qkvhghggag gpglsapegw apphsppsvl strgsaalga tgsralhtds
      541 p
//
