LOCUS       NM_001107809            5692 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger protein 512B (Zfp512b), mRNA.
ACCESSION   NM_001107809 XM_001057229 XM_230967
VERSION     NM_001107809.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5692)
  AUTHORS   Balestri,F., Barsotti,C., Lutzemberger,L., Camici,M. and Ipata,P.L.
  TITLE     Key role of uridine kinase and uridine phosphorylase in the
            homeostatic regulation of purine and pyrimidine salvage in brain
  JOURNAL   Neurochem Int 51 (8), 517-523 (2007)
   PUBMED   17643556
  REMARK    GeneRIF: At relatively high UTP and CTP levels the inhibition of
            uridine kinase channels uridine towards phosphorolysis. The
            ribose-1-phosphate is then transformed into PRPP, which is used for
            purine salvage synthesis.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474066.1.
            
            [WARNING] On Oct 22, 2024 this sequence was replaced by
            NM_001107809.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_230967.4, XM_001057229.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..5692
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q43"
     gene            1..5692
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /note="zinc finger protein 512B"
                     /db_xref="GeneID:311721"
                     /db_xref="RGD:1305284"
     exon            1..320
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            321..446
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     CDS             323..2950
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /note="uridine kinase-like 1"
                     /codon_start=1
                     /product="zinc finger protein 512B"
                     /protein_id="NP_001101279.1"
                     /db_xref="GeneID:311721"
                     /db_xref="RGD:1305284"
                     /translation="MTESFCVGGGRRLQGSSKSGPGKGGSRKEVQLPLLQDPPKLGMP
                     VVHSGHTVPSQAPLCFDPGNSASDKTEGKKKGRPKAENQALRDIPLSLMNQWKDEFKA
                     HSRVKCPNSGCWLEFPSIYGLKYHYQRCQGGAISDRLAFPCPFCEAAFTSKTQLEKHR
                     IWNHMDHPLPAPKPGPVSRPVTINRPVGVSKPIGVSKPVTVGKPVGVSKPIGISKPVT
                     VSRPIPVTKPVTVSRPMQVSRPVPVTKPIPITKPVPLTKHMPVTKLVTVSKPVPLTKP
                     VPVSRPIVVSKPVPVSRPIAISRHTPPCKMVLLSKSENKTLRATGKNSNKKRAADSLD
                     TCPILPKQARQENGEYGPSTVDQSVTFQLSTDPSNSSLLPGSRPLMGKEALRPIGPVS
                     QPEEDPERTKHRRKQKTPKKFTGEQPSISGTFGLKGLAKAEDKARVHRSKKQEGSGSE
                     EVRKKVLATPVTVSKEAPTPVAHPAPGGPEEQWQRAIHERGEAVCPTCNVVTRKTLVG
                     LKKHMEVCHKLQEALKCQHCRKQFKSKAGLNYHTMAEHSAKPTDAEASEGGEQEERER
                     LRKVLKQMGRLRCPQEGCGAAFSSLMGYQYHQRRCGKPPCEVDSPSFPCTHCGKTYRS
                     KAGHDYHVRSEHTAPPPEEPTDKIPEAEDLLGVERTPSGRIRRTSAQVAVFHLQEIAE
                     DELARDWTKRRMKDDLVPETARLNYTRPGLPTLNPQLLEAWKNEVKEKGHVNCPNDCC
                     EAIYSSVSGLKAHFASCSKGDHLVGKYRCLLCPKEFSSESGVKYHILKTHGENWFRTS
                     ADPPSKHKSQDSLMPRKEKKKSLSGGKKRGRKPKERSSEEPASKLPPNRDDWPPGGRD
                     RGARSSTGKKAGAGKAPEK"
     exon            447..589
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            590..718
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            719..1305
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1306..1532
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1533..1604
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1605..1751
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1752..1876
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1877..1969
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            1970..2068
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2069..2239
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2240..2434
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2435..2536
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2537..2599
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2600..2698
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
     exon            2699..5692
                     /gene="Zfp512b"
                     /gene_synonym="Urkl1; Znf512b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaccccgcgc cccgcgcccc gcgccccggc ccggctctgg ctccggcctt gcccggccgc
       61 accccttggg cgcgctgcag gtaagcgccg gcactgcctg ctctaccgcg gtcccggcgc
      121 cacccgcgcc ccgcaccagc cctgtgcccc gcccgcctcc ccgccgcgcc cggacccgcg
      181 ccgcgcccca ctccccgcgt cggcgccgtc ctcccgcctc ctcctccaga aaaagtcgcc
      241 attttggttc actgccttcg cccccccgcg gtcggcgctt ccgggccagg ctgcagcccg
      301 tgtccggcct caggtgacag agatgacgga atctttctgt gttggaggag gccgtcggct
      361 tcaaggatcc agcaaaagtg gacctggaaa gggaggcagc cggaaggagg tccagcttcc
      421 cttgttgcag gacccaccaa agctggggat gccagtggtc cacagtggac atacagtgcc
      481 tagccaggcc ccactctgct ttgaccccgg aaactcagcc agtgacaaga cagaagggaa
      541 gaaaaaaggg aggccgaaag ccgagaacca agctctccga gatattcctc tctctctgat
      601 gaaccagtgg aaagatgaat tcaaggcaca ctcaagggtg aagtgtccaa actcagggtg
      661 ctggctagag ttccccagca tctatgggct caagtaccac tatcagcggt gccaaggggg
      721 cgctatctca gataggctgg ccttcccttg ccccttctgc gaggccgcat tcacctccaa
      781 gacccagctg gagaagcacc ggatttggaa tcacatggac catcccctac ctgcccccaa
      841 gcctggccca gtcagccggc cagtcaccat caatcggcct gttggggtca gcaagcccat
      901 cggagtgagc aaacctgtta ctgttggcaa accagtggga gtcagcaagc ccattggcat
      961 cagtaagcca gtcacagtta gtaggcctat accagtcacc aagcctgtca cagtcagtag
     1021 gcccatgcaa gtctctaggc ctgtgccagt caccaaaccc atcccaatca ccaaacctgt
     1081 gccactcacc aaacatatgc cagttaccaa gcttgtgaca gtttcaaaac ctgtgccact
     1141 caccaagcca gtaccagtca gcaggcccat tgtggtcagc aagcctgtgc cggtcagcag
     1201 gcccatcgcc atcagcagac acacaccacc ctgcaaaatg gtgttgctgt ccaaatctga
     1261 gaacaaaaca cttcgtgcta caggcaagaa cagcaataag aaaagggctg cagacagttt
     1321 ggacacctgc cccatcctgc ccaagcaggc caggcaggag aatggagagt atggcccatc
     1381 cactgtggac cagagtgtga ccttccaact gagtacagat cctagcaaca gctccctgct
     1441 gccaggcagc aggcccctga tgggcaaaga ggcattgcgg cctataggtc cagtgtccca
     1501 gccagaggag gaccctgagc gcacaaagca cagaaggaag cagaaaacac cgaagaaatt
     1561 cacaggggag cagccatcta tctcagggac ctttgggctc aaaggcctgg ccaaagctga
     1621 agacaaggct cgagttcatc gctccaagaa gcaagaggga tcaggctctg aggaagtgcg
     1681 gaagaaggtg ctggccaccc ctgttactgt cagcaaggag gcaccaactc ctgtggccca
     1741 cccagcccca ggtggccctg aggagcagtg gcaacgagcc atccatgaac ggggggaggc
     1801 tgtctgcccc acctgcaacg tggttacccg gaagaccctc gtggggctca aaaagcacat
     1861 ggaagtatgt cacaagttgc aggaagcact caaatgccag cactgccgaa aacagttcaa
     1921 gtccaaggct ggcctcaact accacaccat ggctgaacac agtgccaagc ccacggatgc
     1981 tgaggcctct gaagggggag aacaggagga gcgggagagg ctacgaaagg tgctgaagca
     2041 gatgggacgg ctgcgctgcc cccaagaggg ttgcggggct gccttctcca gcctcatggg
     2101 ttatcagtac caccagcggc gctgtgggaa gccaccctgt gaggtagaca gtccctcctt
     2161 cccctgtacc cactgtggca agacttatcg atccaaggct ggccacgact atcatgtgcg
     2221 ttcagagcac acagccccgc cccctgagga gcccacagac aagatccccg aggctgagga
     2281 cctgcttggg gtagagcgga ccccaagtgg tcgcatccgt cgtacatcgg cccaggttgc
     2341 cgtgttccat ctacaggaga ttgcagagga tgagctggcc cgggactgga ccaaacgtcg
     2401 catgaaggat gaccttgtgc ctgagactgc acggctcaac tacactcggc caggcctccc
     2461 cacacttaac cctcagctgc tggaggcatg gaagaatgaa gtcaaggaga agggccatgt
     2521 gaactgtccc aatgattgct gtgaagccat ctactccagt gtgtccggcc tcaaggccca
     2581 ttttgccagc tgcagcaagg gggaccacct ggtggggaag taccgctgcc tgctgtgtcc
     2641 caaagagttc agctctgaga gtggtgtcaa gtaccacatc cttaagaccc acggagagaa
     2701 ttggttccgg acttcagctg acccgccttc caaacacaag agccaggact ccttgatgcc
     2761 taggaaagag aagaagaaaa gtctgtcagg aggaaagaag cggggccgca aacccaagga
     2821 acggtcctcc gaggagccag catctaagct cccccctaac agggatgact ggcccccagg
     2881 aggcagagac aggggggctc ggagctccac tgggaagaag gctggagctg ggaaggcacc
     2941 tgaaaagtga gcctagtggg cagggcctac ccatcatgcc ctgcattgtc cagattaggg
     3001 gagccagttc tagaccggtc ctccacctcc acacacaccc ccatctgttc agagggttgg
     3061 caaaccactc tgctctccct gaaagtggtc cttcccctgt ttaggctgcc ccaacatggc
     3121 tagatggggc tccccaggag tgccagggca gcagcaaaag tgcaataggc tggaggaccc
     3181 agccgttcta caaggacatt catggacctg gcaggatcta gagccttggc atcatggggc
     3241 atgaagtgtg cttgaaccgt caaatggccc cagtttccac ctccctctgg cccattaggg
     3301 tccccaatct gactgtttca aggctcagac attcctggtg acccatagtt gtgggctgat
     3361 gaggcacctg agcagtctgg ctgccataac ttggccttgc ctccacccaa cactggaact
     3421 ccagtactcc cagctacctc ccaggacaga ccctgtctac tgccatgctg ccctgacagc
     3481 cacccactca tctgtccttt tgcatccacc tctgaccccc ttgcttctgt tttctacctc
     3541 tctgagcctt ctacccttct ctgtcatccc tgctgtgctt caggcctcac cccacttgac
     3601 tggtgtggtc atggtggagt agctagcctt ccaggcaagg aaagaactct gtgttctacc
     3661 ttcagggagg tccagaccca tagctactga cctgagagaa aagaactagg atgcttcacc
     3721 tccagccttt agtttctaat cttgtggtta gcacccttaa aggtgcctcc ctggagccac
     3781 agctgtgtga aacagaggct ggccagaagg agcctagctt aggagtagca actgtgagag
     3841 attgtatatg tctgttatgc taggtgggcc cataagccaa gttctgtgga aggcctcttt
     3901 tcccctttat tttgtctgct cttgggatct agtggcagtc atttgataaa gaaactgaag
     3961 gatagtagga ggttgggtct cagccagtgt agcaactcta ggctgggcct cacccctttc
     4021 cttaggggcc ctgaggataa cagggtccgc aggttggaca aggccaggaa gagagatctg
     4081 accttcctga ttctgccttc taaccctacc cgctccatct cccaaccctg ctctgagcca
     4141 caccaggagg agaaggctgg aaggggttgg aatgggcttt ttatagtgtg gataggggtg
     4201 gactgaggcc tctgcttctg atcctggatg atgtgaattt tgatatttgc ctctgtgtgt
     4261 ctcctggatg ttgatgccag tcttgttgct gtgacaagta gcaacccttt tttaaaagat
     4321 tctttttttt tttttataca aaactcaaca atcttaatgt catggtgcta agggtttcct
     4381 ggtgccgaag gtattgctgt ggtactaact ggtacctgcc ccctagcctc agcagggatg
     4441 gtttccaaga aggccagctc cagggagatt tgggctgaag tccttgtaca ctcatattta
     4501 gaaaggctct gactctgggc aaggcagcca tggcctggtg tgctgtaggt attgaaacgg
     4561 actctccaat tcctacacac tttgatgtgg tcagagggtg gctacagagt gcgtatggat
     4621 gatccagtgt caaagggtag gctggggctt tggggtgtgg tgtgcaactg tggaagggaa
     4681 gggggccaaa gtgcactttc acaacacctc tgtggggtgt gaccatccac cccagcctct
     4741 caggtacttg gcacttgtag ggagaagtag gacctgggtt tgctggggat tgagtttcca
     4801 ggacatacca ttatgcccat atacaggcct tggtatggga cttggtggtt ctggtaactt
     4861 gatgttagca ctttaaatca gtctttgagg tcagttttgg ggcagctgtc aaaagctgca
     4921 gttggatagg taccagccaa taatgaatga ctggttagtg gcaagctaga ctgcaaagct
     4981 cttccaaggt ggcagggctc atcagtctgc ccacctccct accctggccc aaaggtaacc
     5041 atcagcctac acagatcctc agtaagaggg accatcatgg cagagctcca gaaggtggtg
     5101 ggcatagact tagagggcca aaccaaccct ggctccttgg caaaatgcaa aagtcagggt
     5161 ctctacagat ctacctctgg ctcagcgctt gccctgccct aaaaaacaga agtgccaagg
     5221 gcagacattt catgcagaac cagggtgcac tttatgttcc tgcacaggca gataatggtg
     5281 cctcctggag gctttgggac cttcctgtcc ctatggtgtt tctgaaggga gagctgttcc
     5341 cctgttgggt gaaacccagg tcccttgccc tggaggcctg gtttcccagg tcactcctca
     5401 tacctgactg cagcgcctcc taaactttgg gttccttggt ttggttttaa tgcagttctc
     5461 attacacaag tgcatttctg gctatcactt gtaaccatag atatacatgc atatatattc
     5521 tatctacaaa gtgttttatt tgcaagatgt tttgaggtga gctttggtcc tgcccgcctt
     5581 gtgatcatct gtccccatcc tcatcccctg gcccggagtg gtgcggtggt gggccatcaa
     5641 ctatgtatta aagtcactgt atcaaataaa tgtttattga tttctttttt cc
//
