LOCUS       NP_001258325             579 aa            linear   ROD 27-MAR-2024
DEFINITION  zinc finger protein 496 [Rattus norvegicus].
ACCESSION   NP_001258325 XP_220512
VERSION     NP_001258325.1
DBSOURCE    REFSEQ: accession NM_001271396.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 579)
  AUTHORS   Kahns,S., Losson,R. and Nielsen,A.L.
  TITLE     Nizp1 zinc finger protein localization is determined by SCAN-domain
            inclusion regulated through alternative splicing
  JOURNAL   Biochim Biophys Acta 1799 (8), 539-545 (2010)
   PUBMED   20538088
REFERENCE   2  (residues 1 to 579)
  AUTHORS   Mysliwiec,M.R., Kim,T.G. and Lee,Y.
  TITLE     Characterization of zinc finger protein 496 that interacts with
            Jumonji/Jarid2
  JOURNAL   FEBS Lett 581 (14), 2633-2640 (2007)
   PUBMED   17521633
REFERENCE   3  (residues 1 to 579)
  AUTHORS   Nielsen,A.L., Jorgensen,P., Lerouge,T., Cervino,M., Chambon,P. and
            Losson,R.
  TITLE     Nizp1, a novel multitype zinc finger protein that interacts with
            the NSD1 histone lysine methyltransferase through a unique C2HR
            motif
  JOURNAL   Mol Cell Biol 24 (12), 5184-5196 (2004)
   PUBMED   15169884
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FQ223523.1 and JAXUCZ010000010.1.
            
            On Sep 21, 2012 this sequence version replaced XP_220512.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ223523.1, SRR26643293.62992.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..579
                     /organism="Rattus norvegicus"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     Protein         1..579
                     /product="zinc finger protein 496"
                     /note="zinc finger with KRAB and SCAN domains 17"
                     /calculated_mol_wt=65998
     Region          50..126
                     /region_name="SCAN"
                     /note="SCAN domain; pfam02023"
                     /db_xref="CDD:460417"
     Region          220..>248
                     /region_name="KRAB_A-box"
                     /note="KRAB (Kruppel-associated box) domain -A box;
                     cl02581"
                     /db_xref="CDD:470626"
     Region          <314..567
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          401..421
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(406,408,410,412..413,416..417,420,434,436,440..441,
                     444..445,448,462,464,466,468..469,472..473,476)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          429..449
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          457..477
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          516..537
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          547..567
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..579
                     /gene="Zfp496"
                     /gene_synonym="Zkscan17; Znf496"
                     /coded_by="NM_001271396.1:394..2133"
                     /db_xref="GeneID:287361"
                     /db_xref="RGD:1304611"
ORIGIN      
        1 mptalcprvl apkeseeprk mrsppgenps pqgeppspes srrlfrrfry qeaagpreal
       61 qrlwelcrgw lrlerhtkeq ilellvleqf lailpweiqs wvraqepesg eqavaaveal
      121 erepgrpwqw lkhcedpvvi ddgdgpapqd leqermsaes qsnpdalpga laqdpgllsr
      181 spgqpsedpv pqdavlsqeq svrdaqpvtt cqlppnrvsp fkdmilcfse edwslldpaq
      241 tgfygefiig edyavsmppn espvqlghsh eeenglrvte wtdlqdkeap qascidlqpf
      301 qgeerkkwee lqvpepqscq qvvlppspcp ggdppplknn ldqevtieiv lsssgdedsq
      361 hspycteelr sppenlhslp apqsntrpgg evqssqksyv cpscgkafrw rvnfirhlrs
      421 rreqkphkcs vcgelfsdse dldghlethe aqkpyrctvc gksfrlnshl ishqrihlqp
      481 dkqqplkkne edsletestg tndllekska klgfqcadce ksfqrhdylv rhrrhchlkd
      541 etrpfqcryc vktfrqnydl lrherlhmkr rskqalnsy
//
