LOCUS       NP_001028877            1052 aa            linear   ROD 25-MAR-2024
DEFINITION  E3 SUMO-protein ligase ZNF451 [Rattus norvegicus].
ACCESSION   NP_001028877 XP_237039
VERSION     NP_001028877.2
DBSOURCE    REFSEQ: accession NM_001033705.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 1052)
  AUTHORS   Cappadocia,L., Pichler,A. and Lima,C.D.
  TITLE     Structural basis for catalytic activation by the human ZNF451 SUMO
            E3 ligase
  JOURNAL   Nat Struct Mol Biol 22 (12), 968-975 (2015)
   PUBMED   26524494
REFERENCE   2  (residues 1 to 1052)
  AUTHORS   Feng,Y., Wu,H., Xu,Y., Zhang,Z., Liu,T., Lin,X. and Feng,X.H.
  TITLE     Zinc finger protein 451 is a novel Smad corepressor in transforming
            growth factor-beta signaling
  JOURNAL   J Biol Chem 289 (4), 2072-2083 (2014)
   PUBMED   24324267
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Nov 27, 2020 this sequence version replaced NP_001028877.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101930.1, SRR26643299.38679.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1052
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q21"
     Protein         1..1052
                     /product="E3 SUMO-protein ligase ZNF451"
                     /calculated_mol_wt=119046
     Region          879..995
                     /region_name="PIN_ZNF451-like"
                     /note="LabA-like PIN domain of human zinc finger protein
                     451 and related proteins; cd18721"
                     /db_xref="CDD:350288"
     CDS             1..1052
                     /gene="Zfp451"
                     /coded_by="NM_001033705.2:173..3331"
                     /db_xref="GeneID:316312"
                     /db_xref="RGD:1305865"
ORIGIN      
        1 mgdpgpeiie svppagpeps estadenedd iqfvsegplr pvleyidlvs sddeepstsh
       61 sdenfkhkdy idhqkdkval tlarlarhve vekqqkeekn rafrekidfq hahglqelef
      121 iqghseteaa rqcvdqwlkm sglrtsains gskksfqsgg rmrrsdksil cpimhcnkef
      181 dnghlllghl krfdhspcdp titlhgplan vfacavcyeh fvtqqqykdh llskaaaadg
      241 hsndlppqii qcfacphcfl lfstkdeclk hmsaknhfhq slklgddkgt arpvsfpsfa
      301 kkllvslckd vpflvkcvac hqtlrshmel sahfrvrcrn agpvaiaeks itqvakeflv
      361 rgycsdcnqv fmdeastqsh knpghkmsfa nsveesvlly chisegsrpp cdlhlfnqpk
      421 isslkrilss kessaedcvi ptkkvnlgvd sqggtarvqr qrstvtawfc ecsrrfpsed
      481 avekhvfsan tmcykcvvcg kvcedsgvmr lhmsrfhgga hlnnflfwcr mckkelirkd
      541 aimahvtefh sghryfyemd eveaavpsss tenhlnadkp pspiavvdhs passpprgrw
      601 qcricedmfd shecvqqhca sltshrfhry scahcrktfh kvetlcrhcq dehsgevrmm
      661 yccglcdlif nkeeaflshy teqhsgdyvf vpektktsik teddfkiiet snllscgche
      721 syickvnrrd dydrclqiml ekgklwfrcg scsataqnla dinthvcqah rkvrgdeeqq
      781 yvikcgvctk afhntesaqq hfhrkhaafq kpvtahvrad hgstgqlaas vshaeknprh
      841 tsyqkcsdve rsaehdvccq nieeevelpd vdylrtmthi vfvdfdnwsn ffghlpghln
      901 qgtfiwgfqg gntnwkpplg ckvynylnri gcfflhprcs krkdaadfai cmhagrldeq
      961 lpkqipftil sgdqgflele nqfkktqrpa hilnphhleg dmmcallnsi sdttkecdsd
     1021 dsmgvkgspv eelratedve leeairrsle em
//
