LOCUS       NP_001178731             977 aa            linear   ROD 03-APR-2024
DEFINITION  zinc finger protein 445 [Rattus norvegicus].
ACCESSION   NP_001178731 XP_236726
VERSION     NP_001178731.1
DBSOURCE    REFSEQ: accession NM_001191802.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 977)
  AUTHORS   Takahashi,N., Coluccio,A., Thorball,C.W., Planet,E., Shi,H.,
            Offner,S., Turelli,P., Imbeault,M., Ferguson-Smith,A.C. and
            Trono,D.
  TITLE     ZNF445 is a primary regulator of genomic imprinting
  JOURNAL   Genes Dev 33 (1-2), 49-54 (2019)
   PUBMED   30602440
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Jul 17, 2010 this sequence version replaced XP_236726.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.748598.1,
                                           SRR22582424.1481872.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..977
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     Protein         1..977
                     /product="zinc finger protein 445"
                     /calculated_mol_wt=113571
     Region          49..161
                     /region_name="SCAN"
                     /note="leucine rich region; smart00431"
                     /db_xref="CDD:128708"
     Region          213..271
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          462..482
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          <465..596
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          490..510
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          536..962
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          545..565
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          573..593
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          626..646
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(631,633,635,637..638,641..642,645,659,661,665..666,
                     725..726,729,743,745,747,749..750,753..754,757)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          654..730
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          738..758
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          788..808
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          816..836
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          844..864
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275370"
     Region          926..946
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          954..974
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..977
                     /gene="Zfp445"
                     /gene_synonym="RGD1559144"
                     /coded_by="NM_001191802.1:208..3141"
                     /db_xref="GeneID:301076"
                     /db_xref="RGD:1559144"
ORIGIN      
        1 mppgrcyaar svqmsrehgr lhmvkkeeee dgcisvetar pqtlnrpgqe lfrqlfrqlr
       61 yhessgplet lsrlqelcrw wmrpdvlska qmlellvleq flsilpgelr twvqlhcpes
      121 gaevvallee lqrdldgtsl kdscltqnpd vhwigtgplq aaqiwspash vgkssaledy
      181 letphgigrg dspavsmpdy fqieesiehq etltfqdvev tfsqeewgcl nsaqrnlyrd
      241 vilenygnvv svvgsspkpa liswlearkp wgmnictvql krepdaapeg gklqiepskf
      301 ilkqepskyt etcvkpsgcp askgtglkes feqksrlqks cgdsvqmkem kkgtdisqka
      361 grkseilrns dilelkhvkc vsvsrkklsf khgydrnfrk sshhynnkyg eglrdtvegf
      421 gvyqntglke nekdrcgetl rksshshley qryysqgslf kcrvcekafk wrsncirhek
      481 ihtgvkpykc sscekafqrl styrlhqkth tkqkhesrky nnalpcsldv shclinqdee
      541 knfycsqcgk hfscrsyale hqrihtqekp yncircrktf rwksnftrhm klhgkevrnq
      601 ercqedfkqn ysqsqvisti ektflcqscg ktftqkksli ehqrihtgek lyqcsgcgkt
      661 fasrssyiih mkqkrhaiki kpesgslpfs qdtafaipqs ghnteepnqc kycgrafhnr
      721 sflliherih trekpykcre cekafrwrsn lyrherkhfl hkrrkyhesk etsnlqskif
      781 idekpfwcqe cgktftrkrs lldhkgihsg errfkcnlce ksfdrnyrlv nhqrihtteq
      841 pfqsqwhdkd fagthahsvd qrkhrtlqse yslqsdkpgl sycqdvrvni qelelsgkkp
      901 ldnpshessm stafqnvptk kachkcstcg ktfrkhshli shkrchtker pfkcivcgkt
      961 fgwssnltrh vkshfrd
//
