LOCUS       NM_001402569            2029 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus zinc finger protein 42 (Zfp42), mRNA.
ACCESSION   NM_001402569 XM_002728408
VERSION     NM_001402569.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2029)
  AUTHORS   Rezende,N.C., Lee,M.Y., Monette,S., Mark,W., Lu,A. and Gudas,L.J.
  TITLE     Rex1 (Zfp42) null mice show impaired testicular function, abnormal
            testis morphology, and aberrant gene expression
  JOURNAL   Dev Biol 356 (2), 370-382 (2011)
   PUBMED   21641340
REFERENCE   2  (bases 1 to 2029)
  AUTHORS   Garcia-Tunon,I., Guallar,D., Alonso-Martin,S., Benito,A.A.,
            Benitez-Lazaro,A., Perez-Palacios,R., Muniesa,P., Climent,M.,
            Sanchez,M., Vidal,M. and Schoorlemmer,J.
  TITLE     Association of Rex-1 to target genes supports its interaction with
            Polycomb function
  JOURNAL   Stem Cell Res 7 (1), 1-16 (2011)
   PUBMED   21530438
REFERENCE   3  (bases 1 to 2029)
  AUTHORS   Kim,J.D., Kim,H., Ekram,M.B., Yu,S., Faulk,C. and Kim,J.
  TITLE     Rex1/Zfp42 as an epigenetic regulator for genomic imprinting
  JOURNAL   Hum Mol Genet 20 (7), 1353-1362 (2011)
   PUBMED   21233130
REFERENCE   4  (bases 1 to 2029)
  AUTHORS   Tarantino,C., Paolella,G., Cozzuto,L., Minopoli,G., Pastore,L.,
            Parisi,S. and Russo,T.
  TITLE     miRNA 34a, 100, and 137 modulate differentiation of mouse embryonic
            stem cells
  JOURNAL   FASEB J 24 (9), 3255-3263 (2010)
   PUBMED   20439489
REFERENCE   5  (bases 1 to 2029)
  AUTHORS   Kristensen,D.M., Nielsen,J.E., Skakkebaek,N.E., Graem,N.,
            Jacobsen,G.K., Rajpert-De Meyts,E. and Leffers,H.
  TITLE     Presumed pluripotency markers UTF-1 and REX-1 are expressed in
            human adult testes and germ cell neoplasms
  JOURNAL   Hum Reprod 23 (4), 775-782 (2008)
   PUBMED   18281244
REFERENCE   6  (bases 1 to 2029)
  AUTHORS   Xu,J., Sylvester,R., Tighe,A.P., Chen,S. and Gudas,L.J.
  TITLE     Transcriptional activation of the suppressor of cytokine
            signaling-3 (SOCS-3) gene via STAT3 is increased in F9 REX1
            (ZFP-42) knockout teratocarcinoma stem cells relative to wild-type
            cells
  JOURNAL   J Mol Biol 377 (1), 28-46 (2008)
   PUBMED   18237746
REFERENCE   7  (bases 1 to 2029)
  AUTHORS   Kim,J.D., Faulk,C. and Kim,J.
  TITLE     Retroposition and evolution of the DNA-binding motifs of YY1, YY2
            and REX1
  JOURNAL   Nucleic Acids Res 35 (10), 3442-3452 (2007)
   PUBMED   17478514
REFERENCE   8  (bases 1 to 2029)
  AUTHORS   Raman,J.D., Mongan,N.P., Liu,L., Tickoo,S.K., Nanus,D.M.,
            Scherr,D.S. and Gudas,L.J.
  TITLE     Decreased expression of the human stem cell marker, Rex-1 (zfp-42),
            in renal cell carcinoma
  JOURNAL   Carcinogenesis 27 (3), 499-507 (2006)
   PUBMED   16344273
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Mar 18, 2022 this sequence version replaced XM_002728408.6.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.75004.1, CK601943.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-422               JAXUCZ010000016.1  55568903-55569324
            423-499             JAXUCZ010000016.1  55572732-55572808
            500-2029            JAXUCZ010000016.1  55576354-55577883
FEATURES             Location/Qualifiers
     source          1..2029
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.1"
     gene            1..2029
                     /gene="Zfp42"
                     /gene_synonym="Zfp971"
                     /note="zinc finger protein 42"
                     /db_xref="GeneID:100361947"
                     /db_xref="RGD:2319133"
     exon            1..422
                     /gene="Zfp42"
                     /gene_synonym="Zfp971"
                     /inference="alignment:Splign:2.1.0"
     exon            423..499
                     /gene="Zfp42"
                     /gene_synonym="Zfp971"
                     /inference="alignment:Splign:2.1.0"
     exon            500..2029
                     /gene="Zfp42"
                     /gene_synonym="Zfp971"
                     /inference="alignment:Splign:2.1.0"
     CDS             570..1487
                     /gene="Zfp42"
                     /gene_synonym="Zfp971"
                     /note="zinc finger protein 971"
                     /codon_start=1
                     /product="zinc finger protein 42 homolog"
                     /protein_id="NP_001389498.1"
                     /db_xref="GeneID:100361947"
                     /db_xref="RGD:2319133"
                     /translation="MNEQMKKMAKTSGQKGPGRRALDRMTLNHDEARPVQNTRVEPPH
                     VTYTIHEEGEISPENEEDVFPNGYLECIIRGEFSEPILEEDLLFKSFESLEEAEQDLS
                     CQVLEASSLLEYMTKGTKQEKRATQEEPQQTVGANSVPECSEYLTSRKLPVGEPSEVD
                     LSYHEQLSGFTGEKLKGGPYCGNISMLECPQAGCKKKLRDKTALRKHMLVHGPRQHVC
                     AECGKAFTESSKLKRHFLVHTGERPFQCTFEGCGKRFSLDFNLRTHVRIHTGEKRFVC
                     PFDGCEKSFIQSNNLKIHILTHAKAGKKC"
ORIGIN      
        1 ctccagatct cttggttatc aaattgcccg agttctcttt tcacttctgt ttctcaggag
       61 tagatccaga aaagtcgtta actttaacca gcgcctactg ctcctttaca accctctagt
      121 ggttttcctt tggtgttgaa ctacagcgca aatgactgtc cgtagaattc ccagcctcct
      181 ttgcggttgg cctcaggccg aggtactact gaccggcttt tctaagaatt acggcttcaa
      241 gcctgactgt gtcggtgtcc ttttgcctgt aatctcagca ccagggaggc agaggcaggc
      301 aatctgtgtt gagttggagg acagcctagt ccagaaagca aattccagga cagccgggct
      361 gccttgagaa agaagccctg tctcaaaaaa ccagagggga aaaaagaacg aaggcttcta
      421 tgctcctgtg cacagaagaa agcaggacct tctcaccgtg ctgcctcgtg ttttgtcacc
      481 agctactgct gaccaaatag caggtgtttg cctgaggtga ctgttgttgg accagtgtca
      541 cctggaagtg atttcctagc taagacaaca tgaatgaaca gatgaagaaa atggcaaaga
      601 caagtggcca gaaagggccg ggcagaaggg ccctcgacag aatgactcta aatcatgacg
      661 aggcaaggcc agttcagaat accagagtgg aacctcccca tgtaacatac accatccacg
      721 aagaaggtga gattagccct gagaatgagg aagatgtctt tcctaatgga tacctagaat
      781 gcatcataag aggggagttt tctgagccca ttttggaaga ggatttactt tttaaatcct
      841 tcgaaagcct agaggaagcg gaacaagacc tttcttgcca ggttctggaa gctagttctc
      901 ttctcgagta catgacaaag gggacaaaac aagagaaaag ggccacacaa gaggagcctc
      961 agcagactgt tggagcgaac tcagttcctg agtgttctga gtacttgaca agcaggaagc
     1021 tccctgttgg agaaccctcg gaagttgatt tatcctatca tgagcagctg tcaggcttta
     1081 ctggagagaa gctaaagggt ggtccatact gtggtaatat ctcgatgctg gagtgtcctc
     1141 aagctgggtg caagaagaag ctgagggata aaactgccct gaggaaacac atgctggtcc
     1201 acggtccccg tcagcacgtg tgtgcagagt gtgggaaagc ttttacagag agctcgaaac
     1261 taaagcggca cttcctggtc catacaggag agaggccttt tcagtgcacc ttcgaaggct
     1321 gtgggaagcg cttctcactg gatttcaact tgcgcaccca tgtccgcatc cacacgggtg
     1381 agaagcgctt tgtgtgtcct tttgatggct gcgagaagag ttttattcag tcaaacaacc
     1441 tgaagattca catcctaact catgcaaagg cagggaagaa atgctgaaag tcgagacaga
     1501 ttgtcccagg ctgagtggtc ttactggcag aggcaccgag gatccatgca ttatgtatga
     1561 gaatattatt tgtggggatg gattctatgg ctaaaataac tttgcaaatc tagaaggcct
     1621 gcttgtattt tttatttact tcattacaca attttaagaa cattgttttt tgtattccat
     1681 ggtgtagttc caacagaaaa gtcaatggtg aaagcataat gtttaatata tgtgctacac
     1741 tgttgaaggt gacagtgttt ttgcatacct aataaaaaat agcttatttt taattatgca
     1801 gttcctaatg ccctagcttt taccctttaa aatgcttcat gggaaatgat cctaaagaat
     1861 gggtaccttt ggcagtagtc aacaaatgaa tacatatttc tacatttttg atttttgttt
     1921 tccttattgt atcaaactat taatcatagt taaatgtgaa tagttatata ataaagttga
     1981 tccatctgaa gattttaggt gtttcaaaat aaaaggaaat aaaacacta
//
