LOCUS       NM_001191620            2715 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger protein 418 (Zfp418), mRNA.
ACCESSION   NM_001191620 XM_218208
VERSION     NM_001191620.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2715)
  AUTHORS   Singh,S.R., Meyer-Jens,M., Alizoti,E., Bacon,W.C., Davis,G.,
            Osinska,H., Gulick,J., Reischmann-Dusener,S., Orthey,E.,
            McLendon,P.M., Molkentin,J.D., Schlossarek,S., Robbins,J. and
            Carrier,L.
  TITLE     A high-throughput screening identifies ZNF418 as a novel regulator
            of the ubiquitin-proteasome system and autophagy-lysosomal pathway
  JOURNAL   Autophagy 17 (10), 3124-3139 (2021)
   PUBMED   33249983
REFERENCE   2  (bases 1 to 2715)
  AUTHORS   Pan,L., Sheng,M., Huang,Z., Zhu,Z., Xu,C., Teng,L., He,L., Gu,C.,
            Yi,C. and Li,J.
  TITLE     Zinc-finger protein 418 overexpression protects against cardiac
            hypertrophy and fibrosis
  JOURNAL   PLoS One 12 (10), e0186635 (2017)
   PUBMED   29065170
  REMARK    Publication Status: Online-Only
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jul 17, 2010 this sequence version replaced XM_218208.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.1218.1,
                                           SRR26360172.335288.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-27                JAXUCZ010000001.1  75614717-75614743
            28-66               JAXUCZ010000001.1  75615306-75615344
            67-193              JAXUCZ010000001.1  75617889-75618015
            194-2715            JAXUCZ010000001.1  75623415-75625936
FEATURES             Location/Qualifiers
     source          1..2715
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q12"
     gene            1..2715
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /note="zinc finger protein 418"
                     /db_xref="GeneID:292548"
                     /db_xref="RGD:1311663"
     CDS             1..1983
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /codon_start=1
                     /product="zinc finger protein 418"
                     /protein_id="NP_001178549.1"
                     /db_xref="GeneID:292548"
                     /db_xref="RGD:1311663"
                     /translation="MAAVKHLAQIPRCTETGMICTQGCVTIEDVTVYFSQEEWKLLDE
                     AQRLLYLDVMLENFTLISSLVYRYEAEAEEKTCAQSLSQTEAPQVRTPKQGQLRQKPH
                     PSDICITVLKDILHLNDLPGQKPYLTEVCTKPQDHKHHRAKNWLKRDVDSLVKSCIFH
                     VAGNPFICSKIGEKFPAIWNLLQPKDIPNGEKQNKIKRGKAFHRDKNNSESDEYKKSS
                     SPQHRLHEYPGVCSAKGGFESNSCEQDLNKYSPAPFRMDQTENRPYECHVCGKWFGQK
                     ATLRIHQRRHTGEKPYKCGECGKSFCQSSNLSEHCRVHSGERPFECLECGKAFGCHSS
                     LLRHQRTHTGEWPYECSDCGRLFRQIVSLITHQRTHTTEKPYECGQCEKSFSHKATLT
                     VHQRVHTGEKPYHCEACGKSFSQSANLIKHSKIHTGEKPYECGECGLCFRQRATLMKH
                     QRTHTSERPYECRECGKFFKQYFYLIEHRRIHTTTEFYECEQCGKSYTQKATLIRHQR
                     VHTGESPYKCEECGKAFEYKSRLKRHQRTHTGERPYECAKCGKFFRESYNLAEHQKIH
                     TKAKPYHCDQCGKCFSRRADLVKHQRVHTGERPYTCGECGKTFSRTTNLVQHRRIHTG
                     ERPYECDQCGKSFSQVSTLTRHQLLHTGEKPYKCSK"
     exon            1..27
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     exon            28..66
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     exon            67..193
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /inference="alignment:Splign:2.1.0"
     exon            194..2715
                     /gene="Zfp418"
                     /gene_synonym="RGD1311663; ZNF418"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggcggctg tgaagcacct ggctcagatt cccagatgta cagaaacggg tatgatctgt
       61 acacagggct gtgtaaccat tgaggacgtg actgtttact tctcccagga agagtggaag
      121 ctcctggatg aagctcagag gctactgtat cttgatgtga tgctggagaa ttttaccctt
      181 atatcctcac tggtttatcg gtatgaagca gaggctgaag aaaaaacctg tgcacagagt
      241 ctttcacaaa ctgaagcacc acaagtcagg actccgaagc aaggtcaact caggcagaag
      301 cctcatccct ctgacatctg tatcaccgtc ctgaaagata tcttgcatct gaacgaccta
      361 cctgggcaaa agccgtattt gaccgaagtg tgtacaaagc cccaggacca taagcatcac
      421 agagccaaga attggttaaa gagagacgtg gactcccttg tgaagagctg tatattccat
      481 gtggcaggga accctttcat ctgtagtaag attggagaga aattcccagc tatatggaat
      541 cttctccaac ccaaggacat ccccaacggt gagaaacaaa ataaaattaa gcgtggaaag
      601 gcttttcaca gggataaaaa taattctgaa tcagatgaat ataagaaatc ttccagcccc
      661 caacacaggc ttcatgaata cccaggagtt tgcagtgcaa aggggggttt tgaatctaac
      721 agttgtgagc aagacttaaa caagtactca cctgcaccat tccggatgga ccagactgaa
      781 aaccgaccat atgagtgtca tgtctgtgga aaatggtttg gccagaaagc cacacttaga
      841 atacaccaga gacgtcatac cggagaaaaa ccatataagt gtggtgaatg tggaaagtct
      901 ttttgtcaaa gctctaacct aagtgaacac tgcagagttc atagtggaga aagacctttt
      961 gagtgtctgg aatgtgggaa agcctttggg tgccattcta gtcttctgcg gcaccagaga
     1021 acacacactg gagaatggcc atatgaatgc agtgactgtg ggagactgtt tagacagatt
     1081 gtcagcctga ttacacacca gaggactcac actaccgaga agccttatga atgtggacag
     1141 tgtgagaagt cttttagtca caaagccact cttactgtac atcagagagt tcacactggg
     1201 gaaaagccct atcactgtga agcctgtggg aaatccttca gccaaagtgc caaccttatt
     1261 aaacactcca aaattcacac tggagaaaag ccttatgagt gtggagaatg cggtctatgc
     1321 tttcgccaga gagctaccct catgaaacac cagagaaccc acacgtcaga aaggccttat
     1381 gaatgtagag aatgtggtaa gttctttaaa caatacttct acctcattga acaccgtagg
     1441 attcacacca caacagaatt ttatgagtgt gaacagtgcg ggaagtctta tacccaaaaa
     1501 gccaccctta tcagacacca acgagtccac acaggagaga gtccttataa atgtgaggag
     1561 tgtggaaaag cctttgaata caaatccaga cttaagcgac atcaaagaac gcacactggt
     1621 gaaaggcctt atgagtgtgc caaatgtggg aaattcttca gagaaagcta caatcttgct
     1681 gaacaccaga aaattcacac taaagcaaag ccttaccatt gtgatcagtg tgggaagtgt
     1741 tttagccgga gagctgactt ggttaaacac cagagagttc acactggtga aagaccttat
     1801 acttgtggtg aatgtgggaa gaccttcagc cgaactacca accttgttca acacagaaga
     1861 attcacactg gggaacggcc atacgagtgt gaccagtgtg ggaaatcttt tagccaggtg
     1921 tctaccctca ctcgacatca gctacttcac actggagaaa aaccgtataa gtgtagcaaa
     1981 tgaaggaaag tctagacagc cctctagcat cttctaacac caaaagatag accatcacag
     2041 ctcccggaag ccaacccttg aaagcaccct caggcctcca aggatattac attgttcact
     2101 gtaacaaact agagagcctc atagagttct aggtcatgta atttgtacca gagctagcct
     2161 gcatgttctg gacagtctgt accccttgcc agagttaaag agctgtcata atgtctcata
     2221 gacactgtct cttctctagc accttgcact gagtgcatat gcaccaccac caccccaccc
     2281 cacccttgca acatgccgta ctctcccctt ccctaataga agcctcaact tcctgtgcct
     2341 tgcaaatgac cttgatccct ttttctcact ggatatttct gggtctgtat tttgcctaaa
     2401 ggaacatggt ctgggatgag tgggaggctc cagcaaggat tatcttctca agtctgtctc
     2461 acatgattcg tgtgactgtt tacatactcc aaatcactag ccaggaactt cctgtcagga
     2521 tgtgcaataa taaaagacct tatttttttt tcccccatgt acttttaatc aagagtttct
     2581 attcacagac ttaggcagcc aaaatactat gataggtcct gtttttgttt tgtttaatta
     2641 tttttattta cattcaagcc gttgccttcc atcacctctc cctcaagtct tcatccccct
     2701 cctttttctc cttgc
//
