LOCUS       NP_062566                589 aa            linear   ROD 31-MAR-2024
DEFINITION  zinc finger protein 386 (Kruppel-like) [Rattus norvegicus].
ACCESSION   NP_062566
VERSION     NP_062566.3
DBSOURCE    REFSEQ: accession NM_019620.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 589)
  AUTHORS   Wang,L., Zheng,A., Yi,L., Xu,C., Ding,M. and Deng,H.
  TITLE     Identification of potential nuclear reprogramming and
            differentiation factors by a novel selection method for cloning
            chromatin-binding proteins
  JOURNAL   Biochem Biophys Res Commun 325 (1), 302-307 (2004)
   PUBMED   15522233
REFERENCE   2  (residues 1 to 589)
  AUTHORS   Bellefroid,E.J., Sahin,M., Poncelet,D.A., Riviere,M.,
            Bourguignon,C., Martial,J.A., Morris,P.L., Pieler,T., Szpirer,C.
            and Ward,D.C.
  TITLE     Kzf1 - a novel KRAB zinc finger protein encoding gene expressed
            during rat spermatogenesis
  JOURNAL   Biochim Biophys Acta 1398 (3), 321-329 (1998)
   PUBMED   9655926
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Feb 11, 2021 this sequence version replaced NP_062566.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC078841.1, U67082.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..589
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q33"
     Protein         1..589
                     /product="zinc finger protein 386 (Kruppel-like)"
                     /note="Kruppel associated box (KRAB) zinc finger 1"
                     /calculated_mol_wt=68225
     Region          6..>45
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          <236..489
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          319..337
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          344..364
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          372..392
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          384..409
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          400..420
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          <424..584
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          428..448
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          456..476
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(461,463,465,467..468,471..472,475,489,491,495..496,
                     499..500,503,517,519,521,523..524,527..528,531)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          484..504
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          512..532
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          540..560
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          568..588
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..589
                     /gene="Zfp386"
                     /gene_synonym="Kzf1; Znf386"
                     /coded_by="NM_019620.3:85..1854"
                     /db_xref="GeneID:25165"
                     /db_xref="RGD:2985"
ORIGIN      
        1 memeqltfrd vavdfspdew ecldppqqrl yrdvmvenyr nlvsvalshh ctqnfspeqi
       61 lkysftkgtn gscglkslyl redciyides kahhgrdmqc litsntkdvi dsrdqehkta
      121 ltitpvrpdt ldepsiynck ypqesfqhdl tlkesledli dglmfhpnss idkelrsrgl
      181 istsdqietf ytersllfsq qiaisydpkh nsidyglpai dplshspngd tdvwespfmy
      241 ketskdfsse sllnncndii lekssqynki cndfdhcssp nkyqytlpkk pfncdnfftq
      301 csklsihqyv qdncyksidc dtmfnktlnv ithkiqhsqk sykcnecgka fkycssyrkh
      361 riihtgekpf kckvcgksft qcaslkkhqr ihtgekpykc eecgrsfnhy silgqhqrih
      421 tgekpykckq cgksftqcss lqkhqvihtg ekpfrcaecg ksftqnstls qhqrihtgek
      481 pykceqcgka ftqcsslrkh qrihtgekpy kceecgrafn crssftkhkr ihtgekpykc
      541 kdcdkafihc tnltqhrrih tgekpykcne cgksfsqcsn lrkheriht
//
