LOCUS       NM_001109470            2293 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus zinc finger protein 385A (Zfp385a), transcript
            variant 2, mRNA.
ACCESSION   NM_001109470 XM_001064465 XM_001064516 XM_001064570 XM_001064633
VERSION     NM_001109470.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2293)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 2293)
  AUTHORS   Beckerman,R. and Prives,C.
  TITLE     Transcriptional regulation by p53
  JOURNAL   Cold Spring Harb Perspect Biol 2 (8), a000935 (2010)
   PUBMED   20679336
  REMARK    Review article
REFERENCE   3  (bases 1 to 2293)
  AUTHORS   Kawagishi,H., Wakoh,T., Uno,H., Maruyama,M., Moriya,A.,
            Morikawa,S., Okano,H., Sherr,C.J., Takagi,M. and Sugimoto,M.
  TITLE     Hzf regulates adipogenesis through translational control of
            C/EBPalpha
  JOURNAL   EMBO J 27 (10), 1481-1490 (2008)
   PUBMED   18418387
REFERENCE   4  (bases 1 to 2293)
  AUTHORS   Das,S., Raj,L., Zhao,B., Kimura,Y., Bernstein,A., Aaronson,S.A. and
            Lee,S.W.
  TITLE     Hzf Determines cell survival upon genotoxic stress by modulating
            p53 transactivation
  JOURNAL   Cell 130 (4), 624-637 (2007)
   PUBMED   17719541
REFERENCE   5  (bases 1 to 2293)
  AUTHORS   Iijima,T., Ogura,H., Takatsuki,K., Kawahara,S., Wakabayashi,K.,
            Nakayama,D., Fujioka,M., Kimura,Y., Bernstein,A., Okano,H.J.,
            Kirino,Y. and Okano,H.
  TITLE     Impaired motor functions in mice lacking the RNA-binding protein
            Hzf
  JOURNAL   Neurosci Res 58 (2), 183-189 (2007)
   PUBMED   17383763
REFERENCE   6  (bases 1 to 2293)
  AUTHORS   Iijima,T., Imai,T., Kimura,Y., Bernstein,A., Okano,H.J., Yuzaki,M.
            and Okano,H.
  TITLE     Hzf protein regulates dendritic localization and BDNF-induced
            translation of type 1 inositol 1,4,5-trisphosphate receptor mRNA
  JOURNAL   Proc Natl Acad Sci U S A 102 (47), 17190-17195 (2005)
   PUBMED   16286649
REFERENCE   7  (bases 1 to 2293)
  AUTHORS   Kimura,Y., Hart,A., Hirashima,M., Wang,C., Holmyard,D., Pittman,J.,
            Pang,X.L., Jackson,C.W. and Bernstein,A.
  TITLE     Zinc finger protein, Hzf, is required for megakaryocyte development
            and hemostasis
  JOURNAL   J Exp Med 195 (7), 941-952 (2002)
   PUBMED   11927637
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Sep 20, 2008 this sequence version replaced NM_001109470.1.
            
            Transcript Variant: This variant (2) differs in the 5' UTR, lacks a
            portion of the 5' coding region, and initiates translation at a
            downstream start codon, compared to variant 1. The encoded isoform
            (2) is shorter than isoform 1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.42656.1,
                                           SRR26643295.30606.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-47                JAXUCZ010000007.1  136353971-136354017 c
            48-184              JAXUCZ010000007.1  136347088-136347224 c
            185-295             JAXUCZ010000007.1  136333883-136333993 c
            296-458             JAXUCZ010000007.1  136331656-136331818 c
            459-701             JAXUCZ010000007.1  136329602-136329844 c
            702-871             JAXUCZ010000007.1  136329101-136329270 c
            872-967             JAXUCZ010000007.1  136328835-136328930 c
            968-2293            JAXUCZ010000007.1  136327393-136328718 c
FEATURES             Location/Qualifiers
     source          1..2293
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q36"
     gene            1..2293
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /note="zinc finger protein 385A"
                     /db_xref="GeneID:685474"
                     /db_xref="RGD:1593784"
     exon            1..47
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..1198
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /note="isoform 2 is encoded by transcript variant 2; zinc
                     finger protein 385"
                     /codon_start=1
                     /product="zinc finger protein 385A isoform 2"
                     /protein_id="NP_001102940.1"
                     /db_xref="GeneID:685474"
                     /db_xref="RGD:1593784"
                     /translation="MILGSLSRAGPLPLLRQPPIMQPPMDLKQILPFPLEPAPTLGLF
                     SNYSTMDPVQKAVLSHTFGGPLLKTKRPVISCNVCQIRFNSQSQAEAHYKGNRHARRV
                     KGIEAAKTRGREPSVRESGDPAPAGSTPPSGDGVAPRPVSMENGLGPAPGSPEKQPGS
                     PSPPSVPESGQGVTKGEGGTSVPASLPGGSKEEEEKAKRLLYCALCKVAVNSLSQLEA
                     HNKGTKHKTILEARSGLGPIKAYPRLGPPTPGEPEAPAQDRTFHCEICNVKVNSEVQL
                     KQHISSRRHRDGVAGKPNPLLSRHKKPRGAAELAGTLTFSKELPKSLAGGLLPSPLAV
                     AAVMAAAAGSPLSLRPAPAAPLLQGPPITHPLLHPAPGPIRTAHGPILFSPY"
     exon            48..184
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            185..295
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            296..458
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            459..701
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            702..871
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            872..967
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
     exon            968..2293
                     /gene="Zfp385a"
                     /gene_synonym="Zfp385"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agaacgacgc ggaaccccgg gagccagggt ccccagcatg atcctcggca gcctgagccg
       61 agcagggccc ctccctctgc tccggcagcc ccccatcatg cagcccccga tggacctgaa
      121 gcagatcctg cccttcccac tggagccagc cccaaccctg ggcctcttca gcaactacag
      181 cacaatggac cctgtacaga aggctgtgct ctcccacaca tttggaggac ccttgctcaa
      241 gaccaagcgg ccagtcattt cctgtaatgt ctgtcaaatc cgcttcaatt ctcagagcca
      301 ggctgaggcg cactacaagg gtaatcgcca tgcccgaaga gtcaaaggca tcgaagctgc
      361 caaaacccga ggcagggagc ctagtgtccg ggaatcagga gatccggctc cagcaggcag
      421 cacccctcca agtggggatg gcgtagcccc tcgtccagtt tccatggaga atggcctggg
      481 tccagcccca ggatccccag agaaacagcc gggctcccca tctcctccca gtgttccaga
      541 gtctggacag ggtgtaacca agggtgaagg ggggacttca gtcccagctt ccctgcctgg
      601 gggtagcaag gaagaagagg agaaagctaa gcgtctgctc tactgtgcac tgtgcaaggt
      661 ggctgtgaac tccctgtccc agcttgaggc acataacaaa ggtactaagc acaagacaat
      721 tttggaggcc cgaagtgggc tgggacccat caaagcttac cctcggttgg ggcctcccac
      781 tcctggggaa ccagaggctc ctgcccagga ccgaaccttc cactgtgaga tctgcaatgt
      841 caaggtcaat tcggaggtcc agctgaaaca gcacatctcc agcaggaggc accgagatgg
      901 cgtggctggg aagcccaacc ctctactgag ccggcacaag aaacctaggg gcgctgcaga
      961 gctggcgggc acgctgactt tctccaagga gctgcccaag tccctggccg gtggcctgct
     1021 ccccagcccc ctagcggtgg ctgcggtgat ggccgctgca gcaggctctc cgctgtccct
     1081 gcgcccagct ccagctgcac ctcttctgca gggaccaccg atcacacacc ctctactcca
     1141 ccctgcccca ggacccatcc gaactgcgca cggacccatc ctcttctccc cctactgacc
     1201 tcaaccctga acccctccca ttgaatcccc cacctccagc cgggacccag gtctccgggc
     1261 tcccagcccg ccccttctcc cggcgctccc tgaatggtct ctccttcccc ccaccccgag
     1321 gtacggggtt ccaggaaagg ggaggggtag cgggggaggg gggcttcaga agggggggaa
     1381 caccccagat ctcagggaac cccgccccct gcccttccct ctcccctaga aaagaggggg
     1441 gccgtctcac ccccgagccc cctcggagac accccctccc aaaagccatg tccatccaac
     1501 ccttcccctc caaacctagc acaaaacggg gttcacaagc catggtcggg gcccgggggg
     1561 agaacatgga ttttcttggc aataagcgga ctctgggact ccggctcccc taccccaaac
     1621 taaagcgctt ccgtgaacaa ccccgtcctc cgcaggggga ggggaacagg cgggatcctg
     1681 ggtccctcgt aagcactttg gttttaccgc ctgcaacctc actgtgcccg ccccgcacca
     1741 tgccccagcc ccaggtccag ctgggcccat cgcagggggc agcacttggg ggcatctcag
     1801 gcacttgggt gggaccaagg agatgccctc atagaccctt ccctcgcctt cttcctcccc
     1861 ggtccgggtt ccattctttt caccagcacc catcgcccaa ggggtaccaa ggggggcaag
     1921 gggtgtccag tccaagccca cccccgcctc gccttccgca aaactgtgag caaaaagcaa
     1981 tagaagcctc gcccccgccc cggcccgtcc ctttccgcag gatttgccgt ctgtagcctc
     2041 cccattccag ttcctagacc tcatggctgc cccctcccgt gacacctcca ctgcacaact
     2101 cgggcggggg cgtgaccccc aacccatccc ttctgtggtt tctatgtggt cagcccttcc
     2161 agccgccgac ccaggatggg gaccggcccc cactggccct cccctcccca tggactcttt
     2221 ctgcttgaca atgtagcaaa cccccttcct ctttctcctt gacaataaag tctagatttg
     2281 ttctgccctc ctg
//
