LOCUS       NM_001034830            3100 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus zinc finger protein 384 (Zfp384), transcript
            variant 2, mRNA.
ACCESSION   NM_001034830
VERSION     NM_001034830.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3100)
  AUTHORS   Hayata,T., Nakamoto,T., Ezura,Y. and Noda,M.
  TITLE     Ciz, a transcription factor with a nucleocytoplasmic shuttling
            activity, interacts with C-propeptides of type I collagen
  JOURNAL   Biochem Biophys Res Commun 368 (2), 205-210 (2008)
   PUBMED   18211825
  REMARK    GeneRIF: These results revealed that Ciz interacts with
            C-propeptides of type I collagen and this association takes place
            in nuclei.
REFERENCE   2  (bases 1 to 3100)
  AUTHORS   Shah,R., Alvarez,M., Jones,D.R., Torrungruang,K., Watt,A.J.,
            Selvamurugan,N., Partridge,N.C., Quinn,C.O., Pavalko,F.M.,
            Rhodes,S.J. and Bidwell,J.P.
  TITLE     Nmp4/CIZ regulation of matrix metalloproteinase 13 (MMP-13)
            response to parathyroid hormone in osteoblasts
  JOURNAL   Am J Physiol Endocrinol Metab 287 (2), E289-E296 (2004)
   PUBMED   15026307
  REMARK    GeneRIF: Nmp4/CIZ is a component of a multiprotein assemblage or
            enhanceosome within the MMP-13 parathyroid hormone response region
            and that, within this context, Nmp4/CIZ promotes both basal
            expression and hormonal synergy.
REFERENCE   3  (bases 1 to 3100)
  AUTHORS   Torrungruang,K., Shah,R., Alvarez,M., Bowen,D.K., Gerard,R.,
            Pavalko,F.M., Elmendorf,J.S., Charoonpatrapong,K., Hock,J.,
            Rhodes,S.J. and Bidwell,J.P.
  TITLE     Osteoblast intracellular localization of Nmp4 proteins
  JOURNAL   Bone 30 (6), 931-936 (2002)
   PUBMED   12052465
  REMARK    GeneRIF: localization in the cytoplasm of osteoblasts[Nmp4 -
            nuclear matrix protein 4]
REFERENCE   4  (bases 1 to 3100)
  AUTHORS   Thunyakitpisal,P., Alvarez,M., Tokunaga,K., Onyia,J.E., Hock,J.,
            Ohashi,N., Feister,H., Rhodes,S.J. and Bidwell,J.P.
  TITLE     Cloning and functional analysis of a family of nuclear matrix
            transcription factors (NP/NMP4) that regulate type I collagen
            expression in osteoblasts
  JOURNAL   J Bone Miner Res 16 (1), 10-23 (2001)
   PUBMED   11149472
REFERENCE   5  (bases 1 to 3100)
  AUTHORS   Nakamoto,T., Yamagata,T., Sakai,R., Ogawa,S., Honda,H., Ueno,H.,
            Hirano,N., Yazaki,Y. and Hirai,H.
  TITLE     CIZ, a zinc finger protein that interacts with p130(cas) and
            activates the expression of matrix metalloproteinases
  JOURNAL   Mol Cell Biol 20 (5), 1649-1658 (2000)
   PUBMED   10669742
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001034830.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB019281.1, SRR26643290.17990.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-139               JAXUCZ010000004.1  159497179-159497317
            140-199             JAXUCZ010000004.1  159497821-159497880
            200-270             JAXUCZ010000004.1  159511707-159511777
            271-508             JAXUCZ010000004.1  159512038-159512275
            509-556             JAXUCZ010000004.1  159512511-159512558
            557-893             JAXUCZ010000004.1  159512755-159513091
            894-1118            JAXUCZ010000004.1  159518805-159519029
            1119-1301           JAXUCZ010000004.1  159519694-159519876
            1302-1380           JAXUCZ010000004.1  159521240-159521318
            1381-1539           JAXUCZ010000004.1  159523729-159523887
            1540-3100           JAXUCZ010000004.1  159524450-159526010
FEATURES             Location/Qualifiers
     source          1..3100
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q42"
     gene            1..3100
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /note="zinc finger protein 384"
                     /db_xref="GeneID:171018"
                     /db_xref="RGD:708346"
     exon            1..139
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            140..199
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            200..270
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..1950
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /note="isoform 1 is encoded by transcript variant 2;
                     nuclear matrix transcription factor 4; nuclear matrix
                     protein 4; Cas-associated zinc finger protein"
                     /codon_start=1
                     /product="zinc finger protein 384 isoform 1"
                     /protein_id="NP_001030002.1"
                     /db_xref="GeneID:171018"
                     /db_xref="RGD:708346"
                     /translation="MEESHFNSNPYFWPSIPTVSGQIENTMFINKMKDQLLPEKGCGL
                     APPHYPTLLTVPASVSLSSGISMDTESKSEQLTPHSQASVTQNITVVPVPSTGLMTAG
                     VSCSQRWRREGSQSRGPGLVITSPSGSLVTTASSAQTFPISTPMIVSALPPGSQALQV
                     VPDLSKKVASTLTEEGGGGGGGGGTVAPPKPPRGRKKKRMLESGLPEMNDPYVLAPGD
                     DDDHQKDGKTYRCRMCSLTFYSKSEMQIHSKSHTETKPHKCPHCSKTFANSSYLAQHI
                     RIHSGAKPYSCNFCEKSFRQLSHLQQHTRIHSKMHTETIKPHKCPHCSKTFANTSYLA
                     QHLRIHSGAKPYNCSYCQKAFRQLSHLQQHTRIHTGDRPYKCAHPGCEKAFTQLSNLQ
                     SHRRQHNKDKPFKCHNCHRAYTDAASLEAHLSTHTVKHAKVYTCTICSRAYTSETYLM
                     KHMRKHNPPDLQQQVQAAAAAAAVAQAQAQAQAQAQAQAQAQAQAQAQAQAQAQASQA
                     SQQQQQQQPPPPQPPHFQSPGAAPQGGGGGDSNQNPPPQCSFDLTPYKPAEHHKDICL
                     TVTTSTIQVEHLASS"
     exon            271..508
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            509..556
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            557..893
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            894..1118
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            1119..1301
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            1302..1380
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            1381..1539
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
     exon            1540..3100
                     /gene="Zfp384"
                     /gene_synonym="Ciz; Nmp4; Znf384"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gggacgtccc aaagaccggt ctttgaggaa ggagtgggac ttgacatcgg aaggacccag
       61 ttcggtgtct caggggagcg aaggttttag ggggccagct gggagtctcc agtatataga
      121 ccactgaagg ttgaaggaga aagttcagga gccctggaaa ggagaaggaa taagacgaca
      181 ggaggaagag agagagaggg gagaatggaa gagtctcact tcaattctaa cccgtacttc
      241 tggccttcta tccccacggt ctcagggcag attgaaaaca ctatgttcat caacaagatg
      301 aaggatcagc tgttgccaga gaagggctgt ggactggcac cacctcacta tcccactttg
      361 ctgacagtgc ctgcctcagt gtccctgtcc tctggcatca gcatggacac agagtccaag
      421 tcagaacagc tgaccccaca cagtcaggca tctgttaccc agaacatcac agtggtccct
      481 gtaccatcta caggactcat gactgcggga gtctcctgtt ctcagaggtg gagaagagaa
      541 gggagtcaat caaggggtcc tggtttggta atcacatccc cttcaggctc tcttgtgacc
      601 acagcctcat cagctcagac tttccctatc tcgactccca tgattgtctc agctcttccc
      661 cctggctcac aagccctaca ggtggtccct gacctctcca agaaggtagc atcaacccta
      721 actgaggaag gaggcggagg tggtggtgga ggtggcactg tggctcctcc taaacctcct
      781 cggggccgca agaagaagcg gatgctggaa tcagggcttc ctgagatgaa tgacccttac
      841 gtccttgccc ctggggatga cgatgaccat cagaaagatg gcaagaccta caggtgccgg
      901 atgtgctcac tgaccttcta ctcaaagtcg gagatgcaga tccactccaa gtcacacacc
      961 gagaccaagc cccacaagtg cccacactgc tccaagacct tcgccaacag ctcctacctg
     1021 gcccagcaca tccgtatcca ttcaggggcc aagccctata gttgtaactt ttgtgagaaa
     1081 tccttccgtc agctctcaca cctgcagcag cacacccgga ttcactccaa gatgcacacg
     1141 gagaccatca agccccacaa gtgcccgcac tgctccaaga ccttcgccaa cacctcctac
     1201 ctggcccagc acctccgtat ccactcgggg gccaagccct acaactgttc ctactgccag
     1261 aaggccttcc gccagctctc ccacctccag cagcacacac gaatccacac tggcgataga
     1321 ccatacaaat gtgcacaccc gggctgcgag aaggctttca cacaactctc caacctgcag
     1381 tctcacagac ggcagcacaa caaagataaa cccttcaagt gccacaactg tcaccgagca
     1441 tacacagacg cagcctcact agaggctcat ttatctacac acacagtgaa gcacgccaag
     1501 gtttatacct gcacaatctg tagtcgggca tatacatcag aaacatatct tatgaaacat
     1561 atgcgcaaac acaaccctcc tgatctccaa caacaagtgc aagcggcggc agcggcagcg
     1621 gcagtggccc aggctcaggc ccaggctcag gctcaggccc aggcccaggc tcaggcccag
     1681 gcccaggccc aggctcaggc tcaggcccag gcccaagctt cacaggcatc acagcagcag
     1741 caacagcagc agccaccacc tccacaacca ccacacttcc agtctcctgg ggcagctccc
     1801 cagggagggg gtggtgggga cagcaaccag aaccctccac cccagtgttc ctttgacctg
     1861 accccctata agccggcaga gcatcataaa gacatctgcc tcactgtcac caccagcacc
     1921 atccaggtgg aacacctggc cagctcttag agatccgtac tgccatccat tggaaagggg
     1981 agaagtcctg gtccctcctt tgtcaactct tcttggtggg aaagttctct tcttccttga
     2041 caagtcctgt ctccagctcc ttgggtctca ggcatggctt ttcttcgcaa gataaccatc
     2101 cttaatctca gctgctcctg attggccaag gaatcctgag ctgatagtgt tatccaacag
     2161 cccccatcca agcagagctt ttaaaactgg ggcttggtgc ttgagagaag gatccgctgt
     2221 aacctcacat cttgtccagt gtgtgggcga ttacctttct ctccatcctc aaagttgggg
     2281 ctgatagaag actagtggct ggccctccca gataacagag aaggaagctc taaatgtcgc
     2341 cagccttccg ttctatgctt acctgtaaaa gaacagattt tgcacgtggc ctgatccctg
     2401 tgagccattt tcttcccctt acatggtctc acttcatatt gggtggtgac tatacctttt
     2461 ttatttgtaa ggggggcaat agctgataca tggtcaccaa ggtgccagag attccccagg
     2521 tgaccaacgg tggcttaaga gtgtgagtta ccatttttcc ttacaacctc cttccttctc
     2581 tgccaaccaa gggcctatat actcagtctc actaccccag tccaaggagc tctgggagct
     2641 gtgtaagctg tgttctctgc gatgccatct gggctttgca gagaagggag aattcagggc
     2701 acacacagga ctggacttag cctccctagg tgccacggtc agatgccgga catggattta
     2761 tatataaata tatatatata aatatatata tatacctgct catcacggcc atctttgttg
     2821 taaccatttc tgtgtttata aatgcattat ctctgagaat tttcatattg atgttttatt
     2881 tttgtcttat tttttttttc tccaccttgt cctctggcca tggcatttta attttctttt
     2941 ccctttcaat ttttttaatc atgggaaatt tcagataaaa gaaaattaaa ataatcagga
     3001 attatacagt tgttataaag caatttaaaa atgaaaaact tatgtacaaa ctaaggggtg
     3061 tttttagaac attgtacaga aataaatttg tgtttaagga
//
