LOCUS       NP_478116                626 aa            linear   ROD 03-APR-2024
DEFINITION  zinc finger protein 37 [Rattus norvegicus].
ACCESSION   NP_478116 XP_232947
VERSION     NP_478116.2
DBSOURCE    REFSEQ: accession NM_058209.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 626)
  AUTHORS   Vanden Heuvel,J.P., Holden,P., Tugwood,J., Ingle,C., Yen,W.,
            Galjart,N. and Greenlee,W.F.
  TITLE     Identification of a novel peroxisome proliferator responsive cDNA
            isolated from rat hepatocytes as the zinc-finger protein ZFP-37
  JOURNAL   Toxicol Appl Pharmacol 152 (1), 107-118 (1998)
   PUBMED   9772206
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB727538.1 and BC166844.1.
            
            On May 29, 2008 this sequence version replaced NP_478116.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760389
                              [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     Protein         1..626
                     /product="zinc finger protein 37"
                     /note="zfp-37"
                     /calculated_mol_wt=70743
     Region          41..89
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          243..262
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          273..>598
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          289..309
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          317..337
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          345..365
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          373..393
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          401..421
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          429..449
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(434,436,438,440..441,444..445,448,462,464,468..469,
                     472..473,476,490,492,494,496..497,500..501,504)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          457..477
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          485..505
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          513..533
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          541..561
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(546,548,550,552..553,556..557,560,574,576,580..581,
                     584..585,588,602,604,606,608..609,612..613,616)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          569..589
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          595..617
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          597..617
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..626
                     /gene="Zfp37"
                     /coded_by="NM_058209.2:1..1881"
                     /db_xref="GeneID:115768"
                     /db_xref="RGD:620723"
ORIGIN      
        1 msasdsnkdl tkpeavgrrs tdkarrpkem atpepaesda keweqlepgq rnvykdtkle
       61 tcsnpasmgn qdpkqglvsk ldgeeerwss vranknssss lhrlkktgts akvqqdgaqt
      121 egkqkfqrkl tsevtfrkks snskkssect llekknvhsk hdpsekrlhk snlygknlnq
      181 nldlpsqiki sakkkpdtan eyrkslshsa sdvnrdeist rkkcdkspnn klfgkgdknq
      241 tgkkcekvcr hsashtkedk ihtgekrksp crspsksdka pgsgkpyecn qcgkvlshkq
      301 glldhqrtht gekpyecnec giafsqkshl vvhqrthtge kpyecvqcgk ahghkhaltd
      361 hlrihtgekp ykcnecgktf rhssnlmqhi rshtgekpye ckecgksfry nssltehvrt
      421 htgeipyecn ecgkafkygs sltkhmriht gekpfectec gktfskkshl vihqrthtke
      481 kpykckecgk afghssslty hlrthtgdcp fecnqcgkaf kqiegltqhq rvhtgekpye
      541 cvecgkafsq kshlivhqrt htgekpfecy ecgkafnaks qlvihqrsht gekpyecvec
      601 gkafkqnasl trhmkihsee qsqeed
//
