LOCUS       NM_017172               2742 bp    mRNA    linear   ROD 17-FEB-2024
DEFINITION  Rattus norvegicus zinc finger protein 36, C3H type-like 1
            (Zfp36l1), mRNA.
ACCESSION   NM_017172
VERSION     NM_017172.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2742)
  AUTHORS   Prenzler,F., Fragasso,A., Schmitt,A. and Munz,B.
  TITLE     Functional analysis of ZFP36 proteins in keratinocytes
  JOURNAL   Eur J Cell Biol 95 (8), 277-284 (2016)
   PUBMED   27182009
REFERENCE   2  (bases 1 to 2742)
  AUTHORS   Galloway,A., Saveliev,A., Lukasiak,S., Hodson,D.J., Bolland,D.,
            Balmanno,K., Ahlfors,H., Monzon-Casanova,E., Mannurita,S.C.,
            Bell,L.S., Andrews,S., Diaz-Munoz,M.D., Cook,S.J., Corcoran,A. and
            Turner,M.
  TITLE     RNA-binding proteins ZFP36L1 and ZFP36L2 promote cell quiescence
  JOURNAL   Science 352 (6284), 453-459 (2016)
   PUBMED   27102483
REFERENCE   3  (bases 1 to 2742)
  AUTHORS   Chen,M.T., Dong,L., Zhang,X.H., Yin,X.L., Ning,H.M., Shen,C.,
            Su,R., Li,F., Song,L., Ma,Y.N., Wang,F., Zhao,H.L., Yu,J. and
            Zhang,J.W.
  TITLE     ZFP36L1 promotes monocyte/macrophage differentiation by repressing
            CDK6
  JOURNAL   Sci Rep 5, 16229 (2015)
   PUBMED   26542173
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2742)
  AUTHORS   Adachi,S., Homoto,M., Tanaka,R., Hioki,Y., Murakami,H., Suga,H.,
            Matsumoto,M., Nakayama,K.I., Hatta,T., Iemura,S. and Natsume,T.
  TITLE     ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK
            pathway
  JOURNAL   Nucleic Acids Res 42 (15), 10037-10049 (2014)
   PUBMED   25106868
REFERENCE   5  (bases 1 to 2742)
  AUTHORS   Zekavati,A., Nasir,A., Alcaraz,A., Aldrovandi,M., Marsh,P.,
            Norton,J.D. and Murphy,J.J.
  TITLE     Post-transcriptional regulation of BCL2 mRNA by the RNA-binding
            protein ZFP36L1 in malignant B cells
  JOURNAL   PLoS One 9 (7), e102625 (2014)
   PUBMED   25014217
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 2742)
  AUTHORS   Phillips,R.S., Ramos,S.B. and Blackshear,P.J.
  TITLE     Members of the tristetraprolin family of tandem CCCH zinc finger
            proteins exhibit CRM1-dependent nucleocytoplasmic shuttling
  JOURNAL   J Biol Chem 277 (13), 11606-11613 (2002)
   PUBMED   11796723
REFERENCE   7  (bases 1 to 2742)
  AUTHORS   Lai,W.S. and Blackshear,P.J.
  TITLE     Interactions of CCCH zinc finger proteins with mRNA:
            tristetraprolin-mediated AU-rich element-dependent mRNA degradation
            can occur in the absence of a poly(A) tail
  JOURNAL   J Biol Chem 276 (25), 23144-23154 (2001)
   PUBMED   11279239
REFERENCE   8  (bases 1 to 2742)
  AUTHORS   Lai,W.S., Carballo,E., Thorn,J.M., Kennington,E.A. and
            Blackshear,P.J.
  TITLE     Interactions of CCCH zinc finger proteins with mRNA. Binding of
            tristetraprolin-related zinc finger proteins to Au-rich elements
            and destabilization of mRNA
  JOURNAL   J Biol Chem 275 (23), 17827-17837 (2000)
   PUBMED   10751406
REFERENCE   9  (bases 1 to 2742)
  AUTHORS   Corps,A.N., Pascall,J.C., Hadfield,K.M. and Brown,K.D.
  TITLE     Identification of a functional promoter element in the 5'-flanking
            region of the rat cMG1/TIS11b gene
  JOURNAL   Biochem J 311 (Pt 1) (Pt 1), 251-258 (1995)
   PUBMED   7575462
REFERENCE   10 (bases 1 to 2742)
  AUTHORS   Gomperts,M., Pascall,J.C. and Brown,K.D.
  TITLE     The nucleotide sequence of a cDNA encoding an EGF-inducible gene
            indicates the existence of a new family of mitogen-induced genes
  JOURNAL   Oncogene 5 (7), 1081-1083 (1990)
   PUBMED   1695727
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JACYVU010000164.1.
            
            [WARNING] On Mar 27, 2024 this sequence was replaced by
            NM_017172.3.
            
            On Nov 26, 2020 this sequence version replaced NM_017172.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: X52590.1, CB792652.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132294, SAMD00132298
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-170               JACYVU010000164.1  75223742-75223911   c
            171-2742            JACYVU010000164.1  75218868-75221439   c
FEATURES             Location/Qualifiers
     source          1..2742
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..2742
                     /gene="Zfp36l1"
                     /gene_synonym="Berg36; Brf1; cMG1; ERF1; TIS11b"
                     /note="zinc finger protein 36, C3H type-like 1"
                     /db_xref="GeneID:29344"
                     /db_xref="RGD:62009"
     exon            1..170
                     /gene="Zfp36l1"
                     /gene_synonym="Berg36; Brf1; cMG1; ERF1; TIS11b"
                     /inference="alignment:Splign:2.1.0"
     CDS             114..1130
                     /gene="Zfp36l1"
                     /gene_synonym="Berg36; Brf1; cMG1; ERF1; TIS11b"
                     /note="zinc finger protein 36, C3H1 type-like 1;
                     EGF-inducible protein CMG1; butyrate response factor 1;
                     ZFP36-like 1; TPA-induced sequence 11b"
                     /codon_start=1
                     /product="mRNA decay activator protein ZFP36L1"
                     /protein_id="NP_058868.1"
                     /db_xref="GeneID:29344"
                     /db_xref="RGD:62009"
                     /translation="MTTTLVSATIFDLSEVLCKGNKMLNYSTPSAGGCLLDRKAVGTP
                     AGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPTLSSRDSRFRDRSFSEGGERLLPTQ
                     KQPGSGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRT
                     FHTIGFCPYGPRCHFIHNAEERRALAGGRDLSADRPRLQHSFSFAGFPSAAATAAATG
                     LLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTT
                     FLFRPMSESPHMFDSPPSPQDSLSDHEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLS
                     ISDD"
     exon            171..2742
                     /gene="Zfp36l1"
                     /gene_synonym="Berg36; Brf1; cMG1; ERF1; TIS11b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccgggagcag gcgtgtggga ctcctgaccg gagagccgga ggctgcgcct tccccgcacc
       61 gggaccttca cgacacaaca gatcctagtc cttgccccgt gcgaacgccc acgatgacca
      121 ccaccctcgt gtccgccacc attttcgact tgagcgaagt tttatgcaag ggtaacaaga
      181 tgctcaacta cagcactccc agtgctgggg gctgcctgct ggacaggaag gcagtgggca
      241 cccctgctgg cgggggcttc cctcggaggc actcggtcac tctgcccagc tccaagttcc
      301 atcagaacca gcttctcagc agtcttaagg gtgagccggc cccgaccctg agctcacgcg
      361 acagccgctt tcgagaccgc tctttctccg aagggggcga gcggctgctg cccactcaga
      421 agcagcctgg gagcggccag gtcaactcca gccgctacaa aacggagctg tgccgcccct
      481 tcgaagaaaa cggtgcctgt aagtacgggg acaagtgcca gttcgcgcac ggcatccacg
      541 agctccgcag cctgacccgc caccccaagt acaagacgga gctgtgccgc accttccaca
      601 ccatcggctt ttgcccttat gggccccgct gccacttcat tcacaacgcc gaggagcgac
      661 gcgccctggc ggggggccgg gacctctccg ctgaccgtcc ccgcctccag catagcttta
      721 gctttgctgg gtttcccagt gccgctgcca ccgccgctgc cacggggctg ctggacagcc
      781 ccacgtccat caccccaccc cccatcctga gcgccgatga cctcttgggc tcacctaccc
      841 tgcccgatgg caccaataac cccttcgcct tttccagcca ggagctggcg agcctctttg
      901 ctcctagcat ggggctgccc gggggaggct cccccaccac cttcctcttc cggcctatgt
      961 ccgaatcccc tcacatgttt gactctcccc ccagccctca ggattctctc tcggaccatg
     1021 agggctacct gagcagctcc agcagcagcc acagtggctc agactcccct accttggaca
     1081 actcaagacg cctgcccatt ttcagcagac tctccatctc agatgactaa gccagggtag
     1141 ggagggaccc cctgcctcct tcacctctcc accctgcacc ccatcccata ccttcacctc
     1201 cccaccccct aactttcctt caaaccctac attcatacat ttaagctcaa cccctttccc
     1261 agaaccttgg tatgttaccc ttcccccaac ataaggacaa gtcaatttgt tggtagcttc
     1321 tggcttgaaa accccctccc tccatttcat agcccactta accacgcata acagagtccc
     1381 atctttgtca gtagatgcct tttttttcgg cttaagcctt aagtgccaaa tcacaaaaga
     1441 aaaaaagcag taaccgttta cagaagcaac ttagtgcctt gtaatctaac tttgtcactg
     1501 tgactacatt acctcttcaa cgccaggggg cacccgtggg cctcccagag cctctgcccg
     1561 tggggtttgg gggcggggga gcggtgaccc gcaaccagca gctccctcag ctggccacac
     1621 aagtgcacct tcctttcagt ctcccgcaca ttcttcctct tccttgtaga tacttgcctc
     1681 cctcagagaa ttgttgctgg acttgggggg gggcgggggt ttgggtgggt ggggacctat
     1741 tttgacattc aaaacctttt tttttcccag ctcgaacccc tgttgactaa tcttgcctgg
     1801 gtttgtgtag gtctccaggg acaaaggttg aacaagttgg acgaaggttt tgacataagt
     1861 gggactttgt gatttaattt cttttttttc tttttctttc tttttttttt taagtgggga
     1921 ggaaggggaa actagatgga ctatgagaga cttgattttg gtgctaaagt tccccaattc
     1981 atatgtgaca tcttaaaaat gacaacaaat gagagaaaag ctaaaaaaaa aaaaaaaaaa
     2041 aaaaaagaag aaaaccatgt aaggggtgag cagtaatggt attcattcca catacaatat
     2101 ctgtgtaaaa caatttcctg tagacgtagc tttaatggat tttgctctag aataccttag
     2161 gtctacctta gagccctcac gccatgcttt tgtccctggg tttaaacttc atctaacttt
     2221 cagaaattgg agagcaaaaa tgttgcttta tcactgcaca tcaatataaa aaagcttatt
     2281 taacttatca agacgtattt attgccaaac tatgcttttt ttttgttaat tttgttcata
     2341 tttatcggga tgacaaatcc atagaatata ttcttttatg ttaaattatg atcttcatat
     2401 taatcttaaa attttgtgac gtgtctttcc tttttttttt ccacagtttt aatatattat
     2461 tcttcaacaa catttttgta actttacact tttttttggt tattttattt taaaaaaatg
     2521 aaaaattaat ttaaaaaaaa tgcaaaaaac tgttggatta tttattttag aaattctccc
     2581 ctttgtgttg gactgcaaat tgagtttctt tctccttagg cctttcacag gtaggactga
     2641 gaatgtataa gttctgtgac agtacagaag gaaaaccacc atttatgtat agcttctaaa
     2701 agggaaaaca aaaaaaaaaa gagagagaga gaaaaaccct tt
//
