LOCUS       NM_001012030            3114 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus zinc finger protein 281 (Zfp281), mRNA.
ACCESSION   NM_001012030 XM_223091
VERSION     NM_001012030.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3114)
  AUTHORS   Fidalgo M, Faiola F, Pereira CF, Ding J, Saunders A, Gingold J,
            Schaniel C, Lemischka IR, Silva JC and Wang J.
  TITLE     Zfp281 mediates Nanog autorepression through recruitment of the
            NuRD complex and inhibits somatic cell reprogramming
  JOURNAL   Proc Natl Acad Sci U S A 109 (40), 16202-16207 (2012)
   PUBMED   22988117
REFERENCE   2  (bases 1 to 3114)
  AUTHORS   Fidalgo M, Shekar PC, Ang YS, Fujiwara Y, Orkin SH and Wang J.
  TITLE     Zfp281 functions as a transcriptional repressor for pluripotency of
            mouse embryonic stem cells
  JOURNAL   Stem Cells 29 (11), 1705-1716 (2011)
   PUBMED   21915945
REFERENCE   3  (bases 1 to 3114)
  AUTHORS   Zhang X, Diab IH and Zehner ZE.
  TITLE     ZBP-89 represses vimentin gene transcription by interacting with
            the transcriptional activator, Sp1
  JOURNAL   Nucleic Acids Res 31 (11), 2900-2914 (2003)
   PUBMED   12771217
REFERENCE   4  (bases 1 to 3114)
  AUTHORS   Law DJ, Du M, Law GL and Merchant JL.
  TITLE     ZBP-99 defines a conserved family of transcription factors and
            regulates ornithine decarboxylase gene expression
  JOURNAL   Biochem Biophys Res Commun 262 (1), 113-120 (1999)
   PUBMED   10448078
REFERENCE   5  (bases 1 to 3114)
  AUTHORS   Lisowsky T, Polosa PL, Sagliano A, Roberti M, Gadaleta MN and
            Cantatore P.
  TITLE     Identification of human GC-box-binding zinc finger protein, a new
            Kruppel-like zinc finger protein, by the yeast one-hybrid screening
            with a GC-rich target sequence
  JOURNAL   FEBS Lett 453 (3), 369-374 (1999)
   PUBMED   10405178
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC083844.1.
            
            On Feb 11, 2005 this sequence version replaced XM_223091.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC083844.1, CK476002.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..3114
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q13"
     gene            1..3114
                     /gene="Zfp281"
                     /note="zinc finger protein 281"
                     /db_xref="GeneID:305083"
                     /db_xref="RGD:1305139"
     exon            1..80
                     /gene="Zfp281"
                     /inference="alignment:Splign:2.1.0"
     exon            81..3095
                     /gene="Zfp281"
                     /inference="alignment:Splign:2.1.0"
     CDS             95..2764
                     /gene="Zfp281"
                     /codon_start=1
                     /product="zinc finger protein 281"
                     /protein_id="NP_001012030.1"
                     /db_xref="GeneID:305083"
                     /db_xref="RGD:1305139"
                     /translation="MKIGSGFLSGGGGPGSSGGSGSSGSSGSGGSRRAEMEPTFPQSM
                     VMFNHRLPPVTSFTRPAGTAAPPPQCVLSSSTSAAPAAEPPPPPAPDMTFKKEPAASA
                     AAFPSQRTSWGFLQSLVSIKQEKPADPEEQQSHHHHHHHHYGGLFAGAEERSPGLGGG
                     EGGSHGVIQDLSILHQHVQQQPAQHHRDVLLSSSGSRTDDHGNEEPKQDTNVKKAKRP
                     KPESQGIKAKRKPSASSKPLVGEGEGAVLSPSQKPHICDHCSAAFRSSYHLRRHVLIH
                     TGERPFQCSQCSMGFIQKYLLQRHEKIHSREKPFGCDQCSMKFIQKYHMERHKRTHSG
                     EKPYKCDTCQQYFSRTDRLLKHRRTCGEAIAKGAASAEPGSSNHNNMGNLAVLSQGNT
                     SSSRRKSKSKSIAVENKEHKTGKTNESQMSNNINMQSYSVEMPTVSTSGGIIGTGLDE
                     LQKRVPKLIFKKGSRKNTDKSYLNFVSPLPDVAGQKSLSGKPSGSLGIVSNNSVETIS
                     LLQSASGKPGPISSNYDDAMQFSKKRRYLPTASSNSAFSINVGHMVSQQSVIQSAGVS
                     VLDNEAPLSLIDSSALNAEIKSCHDKSGIPDEVLQSILDQYSSKSEPQKEDPFNLTEP
                     RVDLHTSGEHSELVQEEHLSPGTQTPSNDKASVLQEYSKYLQQAFEKSTNAGFTLGHG
                     FQFVSLSSPLHNHTLFPEKQIYTTSPLECGFGQSVTSVLPSSLPKPPFGMLFGSQPGL
                     YLSALDATHQQLTPSQELDDLIDSQKNLETSSAFQSSSQKLTSQKEQQKNLESSTSFQ
                     IPSQELASQIDPQKDIEPRTTYQIENFAQAFGSQFKSGSRVPMTFITNSNGEVDHRVR
                     TSVSDFSGYTNMMSDVSEPCSTRVKTPTSQSYR"
ORIGIN      
        1 ggcttttaat tccattgtgg agaggacggc gttattttta ttaactggag gcgacggcgg
       61 ctgcggcggc ggcggaaccc gcctcctccg gggtatgaaa atcggcagcg ggttcctcag
      121 cggcggcggc ggtcccggca gtagcggtgg tagcggctcc agcggcagct ccggcagcgg
      181 cggcagcagg agagctgaga tggagcccac cttcccccag agtatggtta tgttcaacca
      241 ccggctcccc ccggtcacca gcttcacccg gcctgcgggg acggccgccc ctcccccgca
      301 gtgcgtgtta tcctcctcta cctccgcagc cccggccgct gagccccccc ctccaccagc
      361 cccggacatg actttcaaga aggagccggc ggcgtcagcc gcggccttcc cttcgcagag
      421 gacctcctgg ggattcttgc agtccttggt gagcatcaag caggagaaac ctgcggatcc
      481 tgaggagcag cagtcccacc accatcatca ccaccaccac tatggggggc tgttcgctgg
      541 ggctgaagag agatcaccag gcctaggagg aggggaaggg gggagccacg gcgtcatcca
      601 agacctcagt attctccacc agcatgtcca gcagcaacca gcccagcatc accgcgatgt
      661 attactgagc agcagcggta gcaggactga tgaccatggc aacgaggagc caaagcagga
      721 cactaacgtc aaaaaggcaa agaggccaaa gccagaatct cagggaatca aagccaagag
      781 gaagccaagt gcatcttcca aacctttggt tggagaggga gaaggtgccg tcctgtcccc
      841 aagtcagaaa cctcatatct gtgatcactg tagtgctgct ttcaggagct cctaccacct
      901 gcggagacat gtcctcattc acacaggaga aaggccgttc cagtgcagcc agtgtagtat
      961 gggtttcatt cagaaatacc tactgcagag acacgagaaa attcacagca gagagaagcc
     1021 ctttgggtgc gatcagtgca gcatgaagtt tattcagaag taccatatgg agagacacaa
     1081 gaggacacat agtggagaaa agccatataa gtgtgacact tgccaacagt atttttcaag
     1141 gactgacaga ttgttgaagc acaggcgcac gtgtggtgaa gccatagcaa aaggggccgc
     1201 tagtgcagaa cctgggtcat caaaccataa taatatgggt aatctggctg tgttgtctca
     1261 gggaaataca agttcttcac ggagaaaatc gaagtcaaaa agcatagctg ttgaaaataa
     1321 ggaacacaag actggcaaaa caaacgaatc acagatgtca aacaatataa acatgcagag
     1381 ttactcagta gaaatgccta ctgtgtccac cagtggcggc atcatcggca cggggctcga
     1441 tgagctacag aaaagggtgc caaaactgat ctttaagaaa ggaagcagaa agaatacaga
     1501 taaaagctac cttaattttg tgtcaccgtt accagatgta gctgggcaga aatccttgtc
     1561 tggtaaacca agtggctcgc ttggcatcgt atcgaacaat agcgtggaga ccattagtct
     1621 tctccaaagt gcaagcggca aaccaggccc gataagtagt aattatgatg atgccatgca
     1681 gttctcaaag aagagaagat acttaccaac tgccagcagc aacagtgcct tttctatcaa
     1741 tgtaggacac atggtctccc agcagtcagt cattcagtct gcaggggtca gtgttttgga
     1801 caatgaggcg ccattgtcac ttattgactc ctcagctcta aatgctgaaa ttaagtcttg
     1861 tcacgacaag tctggaattc ctgatgaggt tctacaaagt attttggatc agtactctag
     1921 caagtcagaa ccacagaagg aggatccctt caacttaaca gaaccacgag tggatttaca
     1981 cacctcagga gaacactctg aattggttca agaagagcat ttgagcccag gcacccagac
     2041 accttcaaat gacaaagcaa gcgtgttgca ggagtactcc aaatacctcc agcaggcttt
     2101 tgagaagtcc acgaatgcag gttttaccct cggacatggt ttccagtttg tcagcttatc
     2161 ttcacctctc cacaaccaca ctttgtttcc agaaaaacag atatacacta catctccttt
     2221 ggagtgtggt tttggccaat ctgttacctc agtgttgcca tcttcattgc caaagcctcc
     2281 ttttgggatg ttgtttggat ctcaaccagg tctttattta tctgctttgg atgctacaca
     2341 tcagcagttg acaccttccc aggagctgga tgatctgata gattctcaga agaacttaga
     2401 gacatcatca gccttccagt cctcatctca gaaattgact agccagaagg aacaacagaa
     2461 aaatttagag tcctcaacaa gctttcagat tccatctcag gagttagcta gccagattga
     2521 tcctcagaaa gacatagagc ctagaacaac gtaccagatt gagaactttg cacaagcatt
     2581 cggttctcag tttaagtcgg gcagcagggt gccaatgacc tttatcacta actctaatgg
     2641 agaagtggac catagagtaa ggacttcagt gtcagatttc tcagggtata caaatatgat
     2701 gtctgatgta agtgagccat gtagtacaag agtaaagaca cccaccagcc agagttacag
     2761 gtaaggtctc gagagtgacc aggctgggag tctaatgtaa ttttgtttta ttttgagaac
     2821 actgccattg gaatgtttct acacgatcct attaagaata atgtaatgcc ctttcaatgc
     2881 aacttttcat atttagttta ttttgttagt gtgattttag ctctgtttgt attatgattt
     2941 ttaatcaaaa tcaatagatt aaaaatagtt tgacattcaa agtgacaatg tttagcaatc
     3001 aaatttacat gtacagattg tcagggaata gcccaaaagt tttaaatgca aaaacaaaaa
     3061 aattttaaaa aagcaaaaaa agtacagaaa aaaaaaaaaa aaaaaaaaaa aaaa
//
