LOCUS       NP_001101400             608 aa            linear   ROD 23-MAR-2023
DEFINITION  zinc finger protein 189 [Rattus norvegicus].
ACCESSION   NP_001101400 XP_001054832 XP_232972
VERSION     NP_001101400.1
DBSOURCE    REFSEQ: accession NM_001107930.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 608)
  AUTHORS   Gaudet P, Livstone MS, Lewis SE and Thomas PD.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH474056.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_232972.2, XP_001054832.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FM032651.1, BQ208851.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132276
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..608
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q22"
     Protein         1..608
                     /product="zinc finger protein 189"
                     /calculated_mol_wt=70502
     Region          <10..39
                     /region_name="KRAB_A-box"
                     /note="KRAB (Kruppel-associated box) domain -A box;
                     cd07765"
                     /db_xref="CDD:143639"
     Region          116..506
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          132..152
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          160..180
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          188..208
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(193,195,197,199..200,203..204,207,221,223,227..228,
                     231..232,235,249,251,253,255..256,259..260,263)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          216..236
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          244..264
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          272..292
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          300..320
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          328..348
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(333,335,337,339..340,343..344,347,361,363,367..368,
                     371..372,375,389,391,393,395..396,399..400,403)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          356..376
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          384..404
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          440..460
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          468..488
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(473,475,477,479..480,483..484,487,501,503,507..508,
                     511..512,515,529,531,533,535..536,539..540,543)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          496..516
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          508..533
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          524..544
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          537..561
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          552..572
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          583..603
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..608
                     /gene="Zfp189"
                     /coded_by="NM_001107930.1:351..2177"
                     /db_xref="GeneID:313219"
                     /db_xref="RGD:1306510"
ORIGIN      
        1 maspspples keewgyldaa prslykdvvm dsygklvsld vlnrnedeep tvkeeiekdi
       61 epqgiivtri kseldqdpmg setfelvgrl dkqrgiflwe iprdslteeq kmfrghtnvr
      121 krpnseekch kceecgkrfv rkahfiqhqr vhtgekpfqc necgksfsrs sfviehqrih
      181 tgerpyecny cgktfsvsst lirhqrihtg erpyqcnqck qsfsqrrslv khqrihtgek
      241 phkcsdcgka fswkshlieh qrthtgekpy hctkckksfs rnsllvehqr ihtgerphkc
      301 gecgkafrls tyliqhqkih tgekpflcie cgksfsrssf liehqrihtg erpyqcqecg
      361 ksfsqlcnlt rhqrihtgdk phkceecgka fsrssgliqh qrihirekts pfketkgsfd
      421 pncglviqqe vypkeksykc ddcgktfsvs ahlvqhqrih tgekpylctv cgksfsrssf
      481 liehqrihtg erpylcrqcg ksfsqlcnli rhqgvhtgnk phkceecgka fsrnsgliqh
      541 qrihtgekpy rcekcdksfs qqrslvnhqk ihaevktqei yecdacgeaf tcqisliqhq
      601 klhimwmq
//
