LOCUS       NM_031615               3440 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus zinc finger protein 148 (Zfp148), mRNA.
ACCESSION   NM_031615
VERSION     NM_031615.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3440)
  AUTHORS   Chen,S., Lu,F.F., Seeman,P. and Liu,F.
  TITLE     Quantitative proteomic analysis of human substantia nigra in
            Alzheimer's disease, Huntington's disease and Multiple sclerosis
  JOURNAL   Neurochem Res 37 (12), 2805-2813 (2012)
   PUBMED   22926577
REFERENCE   2  (bases 1 to 3440)
  AUTHORS   Bai,L. and Merchant,J.L.
  TITLE     ATM phosphorylates ZBP-89 at Ser202 to potentiate p21waf1 induction
            by butyrate
  JOURNAL   Biochem Biophys Res Commun 359 (3), 817-821 (2007)
   PUBMED   17560543
  REMARK    GeneRIF: ataxia telangiectasia mutated protein phosphorylation of
            ZBP-89 contributes to Histone deacetylase inhibitors induction of
            p21(waf1) gene expression
REFERENCE   3  (bases 1 to 3440)
  AUTHORS   Bai,L. and Merchant,J.L.
  TITLE     Transcription factor ZBP-89 is required for STAT1 constitutive
            expression
  JOURNAL   Nucleic Acids Res 31 (24), 7264-7270 (2003)
   PUBMED   14654702
  REMARK    GeneRIF: ZBP-89 binds directly to the STAT1 promoter G-rich element
            Erratum:[Nucleic Acids Res. 2004 Feb 24;32(4):1615]
REFERENCE   4  (bases 1 to 3440)
  AUTHORS   Zhang,X., Diab,I.H. and Zehner,Z.E.
  TITLE     ZBP-89 represses vimentin gene transcription by interacting with
            the transcriptional activator, Sp1
  JOURNAL   Nucleic Acids Res 31 (11), 2900-2914 (2003)
   PUBMED   12771217
REFERENCE   5  (bases 1 to 3440)
  AUTHORS   Takeuchi,A., Mishina,Y., Miyaishi,O., Kojima,E., Hasegawa,T. and
            Isobe,K.
  TITLE     Heterozygosity with respect to Zfp148 causes complete loss of fetal
            germ cells during mouse embryogenesis
  JOURNAL   Nat Genet 33 (2), 172-176 (2003)
   PUBMED   12524542
REFERENCE   6  (bases 1 to 3440)
  AUTHORS   Hasegawa,T., Takeuchi,A., Miyaishi,O., Isobe,Ki. and de
            Crombrugghe,B.
  TITLE     Cloning and characterization of a transcription factor that binds
            to the proximal promoters of the two mouse type I collagen genes
  JOURNAL   J Biol Chem 272 (8), 4915-4923 (1997)
   PUBMED   9030551
REFERENCE   7  (bases 1 to 3440)
  AUTHORS   Merchant,J.L., Iyer,G.R., Taylor,B.R., Kitchen,J.R.,
            Mortensen,E.R., Wang,Z., Flintoft,R.J., Michel,J.B. and
            Bassel-Duby,R.
  TITLE     ZBP-89, a Kruppel-like zinc finger protein, inhibits epidermal
            growth factor induction of the gastrin promoter
  JOURNAL   Mol Cell Biol 16 (12), 6644-6653 (1996)
   PUBMED   8943318
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Jun 11, 2015 this sequence version replaced NM_031615.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: U30381.1, SRR26360176.2171274.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760434,
                                           SAMN12840105 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-211               JAXUCZ010000011.1  80890667-80890877   c
            212-293             JAXUCZ010000011.1  80857448-80857529   c
            294-430             JAXUCZ010000011.1  80850624-80850760   c
            431-779             JAXUCZ010000011.1  80842940-80843288   c
            780-905             JAXUCZ010000011.1  80823330-80823455   c
            906-1029            JAXUCZ010000011.1  80813434-80813557   c
            1030-1113           JAXUCZ010000011.1  80812157-80812240   c
            1114-1232           JAXUCZ010000011.1  80789291-80789409   c
            1233-3440           JAXUCZ010000011.1  80786818-80789025   c
FEATURES             Location/Qualifiers
     source          1..3440
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q22"
     gene            1..3440
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /note="zinc finger protein 148"
                     /db_xref="GeneID:58820"
                     /db_xref="RGD:62063"
     exon            1..211
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            212..293
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            294..430
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            431..779
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     CDS             447..2831
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /note="transcription factor ZBP-89; zinc finger
                     DNA-binding protein 89"
                     /codon_start=1
                     /product="zinc finger protein 148"
                     /protein_id="NP_113803.1"
                     /db_xref="GeneID:58820"
                     /db_xref="RGD:62063"
                     /translation="MNIDDKLEGLFLKCGGIDEMQSSRAMVVMGGVSGQSAVSGELQE
                     SVLQDRSLPHQEILAADEVLQESEMRQQDMISHDELMVHEETVKNDEEQTDTHERLPQ
                     GLQYALNVPISVKQEITFTDVSEQLMRDKKQVREPVDLQKKKKRKQRSPAKILTINED
                     GSLGLKTPKSHVCEHCNAAFRTNYHLQRHVFIHTGEKPFQCSQCDMRFIQKYLLQRHE
                     KIHTGEKPFRCDECGMRFIQKYHMERHKRTHSGEKPYQCEYCLQYFSRTDRVLKHKRM
                     CHENHDKKLNRCAIKGGLLTSEEDSGFSTSPKDNSLPKKKRQKPEKKSSGMDKESVLD
                     KSDTKKDRNDYLPLYSSSTKVKDEYMVAEYAVEMPHSSVGGSHLEDASGEIHPPKLVL
                     KKINSKRSLKQPLEQSQTISPLSTYEDSKVSKYAFELVDKQALLDSEGSADIDQVDNL
                     QEGPSKPVHSSTNYDDAMQFLKKKRYLQAASNNSREYALNVGTIASQPSVTQAAVASV
                     IDENTTASILDSQALNVEIKSNHDKNVIPDEVLQTLLDHYSHKANGQHEISFSVADTE
                     VTSSISINSSDVPEVTQSENVGSSSQASSSDKANMLQEYSKFLQQALDRTSQNDAYLN
                     SPSLNFVTDNQTLPNPPAFSSIDKQVYAAMPINSFRSGMNSPLRTTPDKSHFGLIVGD
                     SQHPFPFSGDETNHASATSTADFLDQVTSQKKAEAQPVHQAYQMSSFEQPFRAPYHGS
                     RAGIATQFSTANGQVNLRGPGTSAEFSEFPLVNVNDNRAGMTSSPDATTGQTFG"
     exon            780..905
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            906..1029
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            1030..1113
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1232
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
     exon            1233..3440
                     /gene="Zfp148"
                     /gene_synonym="Zbp-89; Znf148"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tctcgactgc tctgggagga ggaagagaag gaggaagagg aggaggagga gggggaggaa
       61 gaggagaaag gcgcaggggt gggagctgtc gccggagctg ccacagcaaa agttctctcc
      121 cctccccctc gccctcctcg ccgggcccgt gggaaggtcg gagctgcggc cgtctgcagt
      181 cagtgaccgc gcgcctcggc gccagcccgc ggatagaaga gaagaatcag tggcttggaa
      241 atttagccaa gtgatctggc gggatgggct catgcctgac acactttata gaggcatcgg
      301 atggcacaag tgactgagag gatcctgtga gtttctggag cctgtgaaag gtagaaactc
      361 aaccatgatt tctttctcaa ctcaacagca ttcccttcct tgaagtcttc agtttttact
      421 tcagcctcag gcagttatac ttaagcatga acattgacga caaactggaa ggattgtttc
      481 ttaaatgtgg cggcatagac gaaatgcagt cttccagggc aatggttgta atgggtggag
      541 tgtctggcca gtccgccgtg tccggagaac ttcaggagtc agtacttcaa gatcgaagtt
      601 tgcctcacca ggagatcctt gctgctgacg aagtgttaca agagagtgaa atgagacaac
      661 aggatatgat atcccatgat gaactcatgg tccacgagga gacagtgaaa aatgacgaag
      721 agcagacgga cacccacgag cggcttcctc aaggactgca gtatgcgctt aatgtcccca
      781 taagtgtaaa gcaggagatt acttttactg atgtatctga gcaactgatg agagacaaaa
      841 aacaagtgag agagccagta gacttacaga aaaagaagaa gcggaaacaa cgctctcctg
      901 caaaaatcct tacaataaat gaggatggat cacttggttt gaaaacccct aaatctcacg
      961 tctgtgagca ctgcaacgct gcctttagaa cgaactatca cttacagaga catgtcttca
     1021 tccatacagg cgaaaaaccg tttcaatgta gtcagtgtga catgcgtttc atacagaagt
     1081 acctgctcca gagacacgag aagatccata ctggtgaaaa accatttcgc tgcgatgagt
     1141 gtggaatgag attcatacag aaatatcaca tggaaaggca caaaagaact cacagtgggg
     1201 agaagcctta ccagtgtgaa tactgcttac agtatttttc cagaacagat cgtgtattga
     1261 aacataaacg tatgtgccat gaaaatcacg acaaaaaact aaacagatgt gccatcaaag
     1321 gtggccttct gacatcagag gaagattctg gcttttctac gtcaccaaaa gataattcac
     1381 tgccaaaaaa gaaaaggcaa aaacctgaga agaaatcgtc cgggatggac aaggagagtg
     1441 tcctggacaa atctgacacg aagaaagaca gaaacgatta cctgcccctc tactcgtcca
     1501 gcactaaagt gaaggacgag tacatggtgg cggagtacgc tgttgaaatg ccccattcct
     1561 cagtgggagg gtcccattta gaagacgctt ctggagagat acacccaccc aagttggttc
     1621 tcaaaaaaat caatagtaag agaagtctga aacagcccct ggagcaaagt caaaccattt
     1681 cacccctatc cacttacgaa gacagcaaag tttccaagta tgcatttgag cttgtggata
     1741 agcaggcatt actagactcg gaaggcagtg ctgacatcga tcaagtggat aacttgcagg
     1801 aggggcccag caaacccgtg cacagcagta ctaattacga cgacgccatg cagttcctga
     1861 agaagaagcg gtatctccag gctgcaagta acaacagcag ggagtacgca ctgaatgtgg
     1921 gcaccatagc ttctcagcct tctgtgacac aagcagccgt ggccagcgtc attgatgaaa
     1981 acaccacagc atccatacta gattcccagg cactgaatgt ggagattaag agcaatcatg
     2041 acaaaaatgt tattccagat gaggtcctgc agactctgct ggatcattat tcccacaaag
     2101 ctaatggaca gcatgagatt tccttcagcg ttgcagatac cgaagtgact tctagcatat
     2161 caatcaattc ttccgatgta cccgaggtca cccagtcaga gaatgttgga tcaagctccc
     2221 aagcatcctc ctcagataaa gctaacatgt tgcaggagta ctccaagttt ctgcagcagg
     2281 ctttggacag aactagccaa aacgatgcct atttgaacag cccgagcctt aactttgtga
     2341 ctgacaacca gacccttcca aatccgccag cattctcttc catagacaag caagtctatg
     2401 cggccatgcc catcaatagc tttcgatcag gaatgaattc tccactaaga acaactccag
     2461 ataagtccca ctttggacta atagtcggtg actcacagca cccatttccc ttttcaggtg
     2521 acgagacaaa ccacgcctct gccacgtcaa cagcagactt tttggatcaa gtaacttctc
     2581 agaagaaagc tgaggcacag cctgtccacc aggcttacca aatgagctcc tttgaacagc
     2641 ccttccgtgc tccataccat ggatccagag ctggaatagc aactcaattt agcactgcca
     2701 atggacaggt gaaccttcgg ggaccaggga caagtgctga attttcagaa ttccccttgg
     2761 tgaatgtaaa tgataataga gctgggatga catcttcacc agatgccaca actggccaga
     2821 cttttggcta aaaaaaaaaa aaaaaaaaaa aaaaaaatgt gtaaataata ctggcacttt
     2881 agaacagatt aatcgagagt ggggttactc tgtaaaatgg agtgctgtac agatctaaga
     2941 gcagtgcgtt cataacaagc tgataagaat agcaagataa tccagtaact gcatttcgtt
     3001 tggttagtcc gcattccttg aactgcctta cgtgtcgtca ccgttagaga agcgatgcat
     3061 tacctgtttt agatcaggat cttgctattc acccacacca agataaaaga aaaaaagact
     3121 ttcgcacaat tgtttcctaa ctgataacat tgtacatttt taggagcgta gtaattgtgt
     3181 gaaagctcct catactgttt ctgagttttt cagcagagta ttgcacttca gcagggaatc
     3241 cgaggagacg tcacagacag tgaacttaaa gtttcaatgt caagagatta tggcttaaat
     3301 aagtagtttg tcctagaggg ggtaataaaa agaaaccacc tttaaaaatg atatgccata
     3361 tacccttggt tttcattttg cattatattg acatgttttt tttttttttt gaagaaaaaa
     3421 gtaataaatc tgatagtcta
//
