LOCUS       NP_001382483             538 aa            linear   ROD 03-APR-2024
DEFINITION  zinc finger protein 205 [Rattus norvegicus].
ACCESSION   NP_001382483
VERSION     NP_001382483.1
DBSOURCE    REFSEQ: accession NM_001395554.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 538)
  AUTHORS   Iida,R., Ueki,M. and Yasuda,T.
  TITLE     Identification of Rhit as a novel transcriptional repressor of
            human Mpv17-like protein with a mitigating effect on mitochondrial
            dysfunction, and its transcriptional regulation by FOXD3 and GABP
  JOURNAL   Free Radic Biol Med 52 (8), 1413-1422 (2012)
   PUBMED   22306510
REFERENCE   2  (residues 1 to 538)
  AUTHORS   Iida,R., Ueki,M. and Yasuda,T.
  TITLE     A novel transcriptional repressor, Rhit, is involved in
            heat-inducible and age-dependent expression of Mpv17-like protein,
            a participant in reactive oxygen species metabolism
  JOURNAL   Mol Cell Biol 30 (10), 2306-2315 (2010)
   PUBMED   20231359
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360172.2308265.1,
                                           SRR26360190.1170116.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN12840132 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     Protein         1..538
                     /product="zinc finger protein 205"
                     /calculated_mol_wt=59045
     Region          114..165
                     /region_name="KRAB"
                     /note="krueppel associated box; smart00349"
                     /db_xref="CDD:214630"
     Region          294..314
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(299,301,303,305..306,309..310,313,327,329,333..334,
                     337..338,341,355,357,359,361..362,365..366,369)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          306..329
                     /region_name="zf-H2C2_2"
                     /note="Zinc-finger double domain; pfam13465"
                     /db_xref="CDD:463886"
     Region          320..342
                     /region_name="zf-C2H2"
                     /note="Zinc finger, C2H2 type; pfam00096"
                     /db_xref="CDD:395048"
     Region          322..342
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          350..370
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          <352..512
                     /region_name="COG5048"
                     /note="FOG: Zn-finger [General function prediction only]"
                     /db_xref="CDD:227381"
     Region          378..398
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          406..426
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Site            order(411,413,415,417..418,421..422,425,439,441,445..446,
                     449..450,453,467,469,471,473..474,477..478,481)
                     /site_type="other"
                     /note="putative nucleic acid binding site [nucleotide
                     binding]"
                     /db_xref="CDD:275368"
     Region          434..454
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          462..482
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     Region          490..510
                     /region_name="C2H2 Zn finger"
                     /note="C2H2 Zn finger [structural motif]"
                     /db_xref="CDD:275368"
     CDS             1..538
                     /gene="Zfp13"
                     /coded_by="NM_001395554.1:483..2099"
                     /db_xref="GeneID:287095"
                     /db_xref="RGD:1304577"
ORIGIN      
        1 msvdsqsiaa tenkekthev sgngqpcgdl lsgqeetvpl easqesthvk aepccerasp
       61 edrtpgtrgs kdkapflpgg vlpspwipil srggrtrerq vaaalltaws qmpvtfedva
      121 lylsreewgr ldhtqqnfyr dilqgkngla lgfpfsrpfw vpqvegkgqa ssssritgae
      181 errdlgsgam emgkmvptla vatledtkpi rtrarwapge dpkygqqvas gpatelardt
      241 geasqlkpap seahplktpe yrgpekpser eealtsgees lvpdsdtgkk tykceqcgkg
      301 fswhshlvth rrthtgekpy tctdcgkrfg rsshliqhqi ihtgekpytc pscwksfshh
      361 stliqhqrih tgekpyvcdr cakrftrrsd lvthqgthtg akphkcpicg kcftqssalv
      421 thqrthtgvk pypcpecgkc fsqrsnliah nrthtgekpy hcldcgksfs hsshltahqr
      481 thrgvrpysc plcgksfsrr snlhrhekih ttgpkalaml mlgaaaagal tapppapt
//
