LOCUS       NM_001191702           13927 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger homeobox 4 (Zfhx4), mRNA.
ACCESSION   NM_001191702 XM_226964
VERSION     NM_001191702.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 13927)
  AUTHORS   Chudnovsky,Y., Kim,D., Zheng,S., Whyte,W.A., Bansal,M., Bray,M.A.,
            Gopal,S., Theisen,M.A., Bilodeau,S., Thiru,P., Muffat,J.,
            Yilmaz,O.H., Mitalipova,M., Woolard,K., Lee,J., Nishimura,R.,
            Sakata,N., Fine,H.A., Carpenter,A.E., Silver,S.J., Verhaak,R.G.,
            Califano,A., Young,R.A., Ligon,K.L., Mellinghoff,I.K., Root,D.E.,
            Sabatini,D.M., Hahn,W.C. and Chheda,M.G.
  TITLE     ZFHX4 interacts with the NuRD core member CHD4 and regulates the
            glioblastoma tumor-initiating cell state
  JOURNAL   Cell Rep 6 (2), 313-324 (2014)
   PUBMED   24440720
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000002.1.
            
            On Jul 17, 2010 this sequence version replaced XM_226964.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMEA5760383, SAMEA5760386
                              [ECO:0006172]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-375               JAXUCZ010000002.1  98315095-98315469   c
            376-3026            JAXUCZ010000002.1  98290462-98293112   c
            3027-3451           JAXUCZ010000002.1  98289107-98289531   c
            3452-3683           JAXUCZ010000002.1  98217635-98217866   c
            3684-3752           JAXUCZ010000002.1  98164667-98164735   c
            3753-3869           JAXUCZ010000002.1  98157008-98157124   c
            3870-4003           JAXUCZ010000002.1  98150934-98151067   c
            4004-4204           JAXUCZ010000002.1  98150541-98150741   c
            4205-4322           JAXUCZ010000002.1  98149908-98150025   c
            4323-9725           JAXUCZ010000002.1  98143680-98149082   c
            9726-13927          JAXUCZ010000002.1  98131996-98136197   c
FEATURES             Location/Qualifiers
     source          1..13927
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q23"
     gene            1..13927
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /note="zinc finger homeobox 4"
                     /db_xref="GeneID:310250"
                     /db_xref="RGD:1563022"
     exon            1..375
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            376..3026
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     CDS             422..11203
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /note="zinc finger homeodomain 4"
                     /codon_start=1
                     /product="zinc finger homeobox protein 4"
                     /protein_id="NP_001178631.1"
                     /db_xref="GeneID:310250"
                     /db_xref="RGD:1563022"
                     /translation="METCDSPPISRQENGQSTSKLCGTTQLDNEVPEKVAGMEPDREN
                     SSSHDNLKTEEHERKSEVLLGFSIENAAATQVTSAKEIPCNECATSFPSLQKYMEHHC
                     PNARLPVLKDDESETSELEDSDVENLTGEIVYQPDGSAYIIEDSKESGQNAQTGANSK
                     LFSTAMFLDSLASVGEKSDQSASGPVSFYPQIINTFHIASSLGKPFTADPAFPNTSAL
                     AGVGPVLHSFRVYDLRHKREKDYLTSDGSAKNSCVSKDVPNNVDLSKFDGCVTDGKRK
                     PVLMCFLCKLSFGYIRSFVTHAVHDHRMTLNDEEQRLLSNKCVSAIIQGIGKDKEPLI
                     SFLEPKKSTSVYPHFSTTNLIGPDPTFRGLWSAFHVENGDSLPAGFAFLKGSASPSSS
                     AEQPLGITQMPKAEVNLGGLSSLVVNTPITSVSLSHSSSESSKMSESKDQENNCERPK
                     ENTVLHPNGECPIKSEPNEPGDEDEEDAYSNELDDEEVGELTDSIGNKDFPLLNQSIS
                     PLSSSVLKFIEKGTSSSSSGTSADDAEKKTQAAAAAAAGRNSGNVTNSYGIGGKDFAD
                     GSVSRDGATAAHPSETTRGDEDSSMTSHQHGFTPSTPGTPGPGGDGSPGNGIECPKCD
                     TVLGSSRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYC
                     KTGQPHPRLARGESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNVQNLQNGNG
                     EQVFGHSAPAPNTSLSGCGTPSPSKPKQKPTWRCEVCDYETNVARNLRIHMTSEKHMH
                     NMMLLQQNMKQIQHNLHLGLAPAEAELYQYYLAQNIGLTGTKLENPADPQLLINPFQL
                     DSATAAALAPGLGELSPYISDPALKLFQCAVCNKFTSDSLEALSVHVNSDRSLPEEDW
                     RAVIGDIYQCKLCNYNTQLKANFQLHCKTDKHMQKYQLVAHIKEGGKTNEWRLKCIAI
                     GNPVHLKCNACDYYTNSVDKLRLHTTNHRHEAALKLYKHLQKQESAVNSESCYYYCAV
                     CDYSSKIKLNLVQHLRSVKHQQTEGLRKLQLHQQGLPPEEDNLSEIFFVKDCPANELE
                     TASLGARTGVDELTEQQLRTASEELSEDAGGALKPTTVTEDDEKETQERDNSEGKVSN
                     NDPGVITPEKELKVAVAGATQPLLLAKEDDTGTKRSKPTEDNKFCPEQFYQCPYCNYN
                     SRDQSRIQMHVLSQHSVQPVICCPLCQDVLSNKMHLQLHLTHLHSVSPDCVEKLLMTV
                     PVPDVMMPNSMLLPATTPEKSERDPPTAMAAAGSGKYSGDSPVDDKSMSGLEDSKVGV
                     EIKNEEQKPAKEPIETSEWSKNSSRDANISDALQDQLSEQQKRQPLSVSDRHVYKYRC
                     NHCSLAFKTMQKLQIHSQYHAIRAATMCNLCQRSFRTFQALKKHLEAGHPELSEAELQ
                     HLYASLPMNGELWAEGETMPQEDHGLEQEMEREYEVDHEGKASPVGSDSSSIPDDLGS
                     EPKRTLPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNSVSHLHKLKKVL
                     QEASSPVPQEANSSTDNKPYKCSICSVAYSQSSTLEIHMRSVLHQTKARAAKLEPSRH
                     LSSGHSITAAVNSPGQGMLESMSLAPVNSKDTHLDAKELNKKQTPEIITAQPTHHPPP
                     RSPAQIQMQLQHELQQQAAFFQPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGA
                     EFSLGPDLALPSSTTFGMPGMTTGMAGSLLEDLKQQIQTQHHVGQTQLQLLQQQAQQY
                     QAAQPQLQPPNQQPPPPPQQQPQQPPSKLLKQEQGSLANTDCQLMKDAPSYKEAEEMT
                     EKEEKPKQESTNDTDGLKDSKDVKKQKSLEPCIPPPRIASGARGNAAKALLENFGFEL
                     VIQYNENRQKVQKKGKSGEGENSEKLECGTCGKLFSNVLILKSHQEHVHGQFFPYGAL
                     EKFARQYREAYDKLYPISPSSPETPPPPPPPPPLPPAPPQPSALGPVKIPNTVSAPLQ
                     APPPTPPPPPPPPPPPPPPPPPPPSAPPQVQLPVSLDLPLFPSIMMQPVQHPALPPQL
                     ALQLPQMDTLSADLTQLCQQQLGLDPNFLRHSQFKRPRTRITDDQLKILRAYFDINNS
                     PSEEQIQEMAEKSGLSQKVIKHWFRNTLFKERQRNKDSPYNFSNPPITVLEDIRIDPQ
                     PTSLEHYKSDASFSKRSSRTRFTDYQLRVLQDFFDTNAYPKDDEIEQLSTVLNLPTRV
                     IVVWFQNARQKARKSYENQAEAKDNEKRELTNERYIRTSNMQYQCKKCNVVFPRIFDL
                     ITHQKKQCYKDEDDDAQDESQTEDSMDATDQVLYKPCTVSGQTDTAKSTAAPVASSGS
                     GTSTPLIPSPKPEPEKNSPKPEYPAEKTKQNDPSLPQGIKSAPSSVSTSSEPQQASIS
                     QPPPQLPKQPQLIGRPPSASQTPIPSSPLQISMTSIQNSLPPQLLQYPCDQCTIAFPT
                     LELWKEHQHMHFLAAQNQFLHSPFLERPMDMPYMIFDPNNPLMTGQLLGSSLTQMPPQ
                     ASTAHTTAPASVAASLKRKLDDKEDNNCSEKEGGNSGEDQHRDKRLRTTITPEQLEIL
                     YEKYLLDSNPTRKMLDHIAREVGLKKRVVQVWFQNTRARERKGQFRAVGPAQSHKRCP
                     FCRALFKAKSALESHIRSRHWNEGKQAGYSLPPSPLISTEDGGESPQKYIYFDYPSLP
                     LTKIDLSSENELASTVSTPVSKTAELSPKNLLSPSSFKAECPEDVENLNAPSADAGYD
                     QNKTDFDETSSINTAISDATTGDEGAADMENTGGSEEVKPALSPKETKSLDSLPKAGT
                     TPTTEVCDDKFLFSLTSPSIHFNDKDGDHDQSFYITDDPDDNADRSETSSIADPSSPN
                     PFGSSNPFKSKSSDRPGHKRFRTQMSNLQLKVLKACFSDYRTPTMQECEMLGNEIGLP
                     KRVVQVWFQNARAKEKKFKINIGKPFMINQSGTDGTKPECTLCGVKYSARLSIRDHIF
                     SKQHISKVRETVGSQLDREKDYLAPTTVRQLMAQQELDRIKKASDVLGLTVQQPGITD
                     NCSLHGISLPAAYPGLPGLPPVILPGMNGPSSLPGFPQNSNTLTPPGAGMLGFPSSAT
                     SSPALSLSSAPTKSLLQTPPPPPPPPPPPPPPPSSLSGQQTEPQNKEPEKKQTKPNKV
                     KKIKEEESEAIKPEKHPKKEEKISSALSVLGKVVGETHMDPTQLQALQNAIAGDPTSF
                     IGGQFLPYFIPGFASYFTPQLPGTVQGGYLPPVCGMESLFPYGPAVPQTLAGLSPGAL
                     LQQYQQYQQSLQDSLQKQQKQQQEQQQKPVPAKTAKGEGDQPQSSNEASETKEEKSTA
                     PESTKEEAQLDSKTTEFSDTCVVPFVKYEFICRKCQMMFTDEDATVNHQKSFCYFGQP
                     LIDPQETVLRVPVSKYQCLACDLALSGNEALSQHLQSSLHKEKTIKQAMRNAKEHVRL
                     LPHSVCSPPPNTSSTSPSAASSNNTYPHLSCFSMKSWPNILFQASARKAASSPSSPPS
                     LSLPSTVTSSLCSTSGVQTSLPTESCSDESDSELSQKLQDLDNSLEVKAKPASGLDGN
                     FSSVRMDMFSV"
     exon            3027..3451
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            3452..3683
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            3684..3752
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            3753..3869
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            3870..4003
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            4004..4204
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            4205..4322
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            4323..9725
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
     exon            9726..13927
                     /gene="Zfhx4"
                     /gene_synonym="RGD1563022"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acacaaagac atgcgcactc aacttaatca gccatttttt taaacagggc taaaacgata
       61 ataattagca gaataaagac atatcggatt ttcatttcct ttcctccttt tcccaacccc
      121 ttcacaacca aacagagaga ccgcggtcgg cacatgcttt aactcctccc ggacccccga
      181 ggaccgctcc gtgcccccca ctttctgctc cagcgttttt attttcaccc aataaagttc
      241 gaggattatt tttttatttt tttatttttt ttaatgaacc ctctcgtttt acttggatgt
      301 gatcagctgt acgtaaaata aaagcaaaac aaaaaagagg cgaagatcga gtaggaactg
      361 caggggaaat ggaaagtccc tgacaggctg gatgaaatga gatccccatg tagcaattgc
      421 catggaaacc tgtgactctc ctcctatctc aaggcaggaa aatgggcaga gcacatcaaa
      481 gctatgtgga actacacaac ttgataatga ggtgccagag aaagttgcag ggatggagcc
      541 tgacagggaa aacagctcct cacatgacaa cctgaaaaca gaggagcatg aacgcaaaag
      601 cgaagtcttg ctgggtttca gcattgagaa tgcagctgcc actcaggtca cctctgcaaa
      661 ggagataccc tgcaacgaat gtgccacttc ttttcccagt ttacagaaat acatggaaca
      721 ccactgccct aatgcccgcc ttcctgtcct gaaggacgat gagagtgaga ccagcgagtt
      781 agaggacagt gacgtggaaa acttaacagg ggagatagtt taccagcctg atgggtcagc
      841 ttatataatt gaggactcca aagaaagtgg gcagaacgca cagactgggg caaacagcaa
      901 actcttttca acagcaatgt ttctggactc cctggcatct gttggagaga agagtgatca
      961 gtctgcttcg ggccctgtgt cgttctaccc acagatcatc aacacttttc atatcgcttc
     1021 atccctcggg aaaccattta cagccgatcc ggctttccca aatacctcag cattagcagg
     1081 agttggtcct gtgttgcaca gtttccgtgt ctatgatctc cgacacaaga gagagaaaga
     1141 ctatctaacc agtgatggct cagccaaaaa ctcctgtgtg tccaaagatg tccctaacaa
     1201 tgtggacttg tccaaattcg atggttgtgt tactgatggg aagaggaaac ctgttttaat
     1261 gtgtttcttg tgcaaattgt cttttggtta tatcaggtcg tttgtaaccc atgctgtgca
     1321 tgatcatcgg atgactctca atgatgagga gcagaggctc ctcagtaata aatgcgtctc
     1381 cgccataata caggggattg gcaaagacaa agaacctctt ataagctttc tggaaccaaa
     1441 aaaatccact tctgtttatc cccatttttc tactacaaac ctcataggac ctgatccaac
     1501 cttccgcggt ttatggagcg cttttcatgt tgaaaacggt gactctttgc cggctggctt
     1561 tgccttcttg aaaggaagcg caagcccttc cagctcagca gaacagccgc tggggatcac
     1621 ccaaatgcca aaggctgaag tgaacctggg ggggctgtct agtttagtag tgaacacccc
     1681 aattacctct gtctccctca gccactcatc atctgagtct agcaagatgt cagagagcaa
     1741 agaccaagag aacaactgtg aaaggccaaa agaaaataca gtcttacacc cgaatgggga
     1801 gtgccctatc aaaagtgaac ccaatgaacc gggagatgag gatgaagagg atgcatattc
     1861 caatgaactc gatgacgagg aagtaggcga actcaccgat agtattggta ataaagactt
     1921 ccctctctta aaccaaagca tttctccttt atcatccagt gtgctaaaat ttattgaaaa
     1981 aggtacctcg tcgtcctcct cggggactag tgctgatgat gcagagaaga aaacacaggc
     2041 cgccgccgct gccgccgccg gaaggaacag tggcaatgtt actaatagct acggcattgg
     2101 tggcaaggac tttgcagacg gaagcgtcag tagagatggt gccacagcag ctcatcccag
     2161 tgaaacgacc cggggagacg aggacagttc aatgacttca caccagcatg gcttcacccc
     2221 gagcacacct ggtacaccag gtcctggagg agatggctcc ccaggcaatg gcattgagtg
     2281 tccaaagtgt gacacggttt tggggtcttc aaggtctctt ggtggtcaca tgactatgat
     2341 gcactcgagg aactcatgta aaaccctgaa atgtcccaaa tgtaactggc actacaaata
     2401 tcagcagact ctggaggccc atatgaagga gaagcacccc gagccaggtg gctcttgtgt
     2461 ttattgtaag actggacagc ctcatcccag gcttgcccgg ggagagagtt acacgtgtgg
     2521 ttataaaccc ttccgttgtg aggtttgtaa ctactctacc actaccaaag gcaacctcag
     2581 tattcatatg cagtctgaca agcacctgaa caatgttcag aatcttcaga atggcaacgg
     2641 cgagcaggtg tttggccact ctgccccagc ccccaacact agcctcagtg gctgcggaac
     2701 accctcccct tccaaaccca agcagaaacc cacctggcgg tgtgaggttt gcgactatga
     2761 aaccaacgtg gctaggaacc ttcggattca catgaccagc gagaaacaca tgcacaatat
     2821 gatgcttctg cagcagaaca tgaaacagat ccagcacaat cttcatctgg gcctcgcccc
     2881 ggcagaggct gagctctacc aatactacct ggctcagaac ataggcctga caggaacgaa
     2941 gctggaaaat cctgcagatc ctcagctcct gattaatccc ttccagctcg actctgctac
     3001 agcagcggct ctggcaccgg gacttggaga gctgtcacct tatatcagtg acccagcgct
     3061 gaagctattc cagtgtgctg tttgcaacaa attcacctct gacagcctgg aggctctaag
     3121 tgtgcatgtg aacagcgacc gctctctccc tgaagaggac tggagagctg taattggaga
     3181 tatctaccag tgcaagctct gcaactacaa cacacagctc aaagccaact tccagctcca
     3241 ctgcaagact gataagcata tgcagaagta ccagctggtg gcccacatca aggaaggggg
     3301 caaaaccaat gagtggaggc tgaagtgcat tgccattggc aaccccgttc acctaaagtg
     3361 taatgcctgt gactactaca ccaacagtgt ggataaatta cgactgcata ctaccaatca
     3421 caggcacgag gcggccctga aactctacaa gcacttgcag aagcaagaga gtgcggtgaa
     3481 ttctgagtcc tgctattact actgtgccgt gtgtgattac tcctccaaga ttaagttaaa
     3541 cctggtccaa caccttcgat cggtgaagca tcagcagact gaggggctcc gaaagctcca
     3601 gctacaccag caaggcctgc caccagagga ggacaacctc agtgagatct tttttgtgaa
     3661 ggactgtcca gcgaatgagc ttgagactgc ctctttggga gccaggactg gtgtggacga
     3721 acttacagag cagcagttga ggacagcctc agaagaactc agtgaagatg caggaggcgc
     3781 tctgaagcct accacagtga ctgaggatga tgagaaagag acacaggaga gagacaacag
     3841 tgaaggcaaa gtctctaata atgaccctgg agtaatcacc ccagagaaag agctgaaagt
     3901 tgctgtggca ggggctacac agccacttct gttggccaaa gaagacgaca caggaaccaa
     3961 aaggtcaaaa cctacagagg acaataaatt ttgtcccgaa cagttctatc agtgtcctta
     4021 ttgtaactac aatagtaggg accaaagtcg gatccagatg catgtcctgt cccagcactc
     4081 tgttcagccc gtcatctgct gtccactttg ccaggatgtc ctcagcaaca aaatgcacct
     4141 gcagctgcat ctgacccatt tgcacagtgt gtctccagac tgtgtggaga agctgcttat
     4201 gacagtgcct gtccctgatg tcatgatgcc aaacagtatg ctactgccag caactacccc
     4261 tgagaaatca gagcgggacc cacctacagc catggcagca gctggttctg gaaaatattc
     4321 aggtgacagc ccagtggatg acaaaagcat gtcagggctt gaggattcga aggtgggtgt
     4381 ggaaataaaa aatgaggagc agaagccagc aaaggagccc atagagacat cagaatggag
     4441 taaaaatagc agtagggatg cgaacatctc agatgctctg caagatcaac tgagtgaaca
     4501 acaaaagagg cagcccttgt cagtttcaga ccgccatgtt tataagtacc gttgtaatca
     4561 ctgtagcttg gcttttaaaa ctatgcagaa gcttcagata cattcccagt atcatgcaat
     4621 tcgggccgct acaatgtgta acctctgcca gcggagtttc cgtacattcc aggctttaaa
     4681 aaaacacttg gaagcaggcc atccggaact gagcgaagct gaactccagc atctatatgc
     4741 ctccttgcca atgaatggtg agctctgggc agagggtgag acaatgcccc aggaagacca
     4801 tggcctagaa caggaaatgg agagagaata tgaggtggac catgaaggga aggcaagtcc
     4861 tgtagggagc gacagcagct ccatcccaga tgacctgggc tcggaaccaa agcggacctt
     4921 accttttaga aaaggaccca actttacaat ggaaaaattc ctcgatccat ctcgtcctta
     4981 caaatgcaca gtgtgtaaag agtccttcac ccaaaaaaac attctcttgg tccattataa
     5041 ttcagtgtct cacttgcata agttgaaaaa ggttttgcaa gaagcctcca gtcctgtccc
     5101 ccaggaagca aatagcagca cagataacaa gccgtacaag tgcagcatct gcagtgttgc
     5161 gtacagccaa agttctacct tggagatcca catgaggtca gtgctccacc agacaaaggc
     5221 cagggctgca aagctggaac caagtaggca cctatccagt gggcacagca ttacagctgc
     5281 tgtcaatagt cctggccaag ggatgttaga gtccatgagc ttagctccgg tcaacagcaa
     5341 agatacccac ttagatgcca aagaattaaa taaaaagcaa actcccgaaa taatcactgc
     5401 gcaacccacc caccatccac cacctcggtc accagcacaa atccagatgc agcttcagca
     5461 tgagttgcag cagcaggctg cgttctttca gccccagttt ctaaacccag cttttctgcc
     5521 tcattttcca atgaccccag aggcgctgct ccagtttcag caaccccaat ttctctttcc
     5581 attctacata cctggggctg agtttagctt ggggccagat ctggccttgc ctagctccac
     5641 cacgtttggg atgccaggta tgacgacagg catggctggt tccttgcttg aagatctgaa
     5701 gcaacagatt caaacgcaac atcacgttgg ccaaactcag ctccaacttc tacaacaaca
     5761 agcacagcag taccaagctg cccagcctca gctgcagcct ccaaatcaac agcctccccc
     5821 accgccacag cagcaacctc aacagccacc aagcaaactg ttgaaacaag agcaaggtag
     5881 cctggcgaat accgactgcc agctcatgaa ggatgcgcca tcttacaagg aggcagaaga
     5941 gatgactgag aaggaagaaa aaccaaagca agaatctaca aatgatactg acggactcaa
     6001 agacagcaaa gacgtaaaga agcaaaaatc tttagaacct tgtattcctc cacccaggat
     6061 agcctctggg gctaggggaa atgcagccaa agctttactg gagaactttg gttttgaact
     6121 ggttattcag tataatgaga acaggcagaa ggtccagaaa aaaggtaaaa gtggagaagg
     6181 tgaaaactct gagaagctgg agtgcggaac ctgtggtaaa ttattctcaa atgttcttat
     6241 tttaaaaagt caccaagaac atgtgcatgg gcaatttttc ccatacggag cactagaaaa
     6301 atttgctcgt caatacaggg aggcctatga caagctttat ccaatttctc cttcttctcc
     6361 agaaacacca ccacctccac ctccgcctcc tcccctgccg cctgcacccc cacaaccttc
     6421 tgcattgggg cctgtgaaaa tcccaaacac agtctctgct cctttgcaag ctccacctcc
     6481 tactcctcca ccaccacctc ctcctcctcc tcctccaccg ccaccaccac ctcctccccc
     6541 atctgcaccc ccacaggtcc aactgcctgt ttcccttgac cttccccttt ttccctccat
     6601 tatgatgcag ccagtgcagc accctgcact tcccccacag cttgccctgc aactgcccca
     6661 gatggacacc ctctcagcag atctcacaca gctttgtcag cagcagctgg ggctagaccc
     6721 taacttcttg agacattctc aattcaaacg gccacggacc cggattacag atgaccagct
     6781 aaaaatcctg agagcttatt ttgacatcaa taattctcca agtgaagaac agatccaaga
     6841 aatggccgag aaatctggcc tctctcaaaa agtcatcaaa cactggtttc gaaatacact
     6901 ctttaaggaa cgacagagaa ataaagattc tccatacaac ttcagtaacc ctcctataac
     6961 tgttttagaa gatattcgaa ttgatccaca acctacatct ttagaacatt acaaatcaga
     7021 tgcctcgttc agcaaaaggt catccagaac aaggtttact gactaccagc ttagggttct
     7081 gcaagacttt tttgacacaa atgcttaccc aaaagatgat gaaatagaac agctctctac
     7141 tgttctcaac ctacccacgc gggttattgt cgtatggttc cagaatgctc gtcagaaagc
     7201 aaggaagagc tacgagaacc aagcagaagc taaagataat gaaaaaagag aactcaccaa
     7261 tgaacgctat attagaacaa gcaacatgca ataccaatgc aaaaagtgca atgtggtttt
     7321 ccccaggatc tttgacttga tcacgcatca gaaaaagcaa tgctataaag atgaagatga
     7381 tgatgcccaa gatgaaagcc aaacagaaga ctccatggat gccactgatc aagtgctgta
     7441 caagccttgc acggtgtctg gacaaacaga tacagccaaa agcactgcag ccccagtagc
     7501 cagttcaggc tctgggacta gcactcccct gattccttct cctaaaccag aacctgagaa
     7561 gaattctcca aaacctgaat atcctgcaga aaagacaaag caaaatgacc cctctcttcc
     7621 tcaaggcatc aagtcagctc cttcatcagt atcgacttct tcagagccac agcaggcgtc
     7681 catatcccag cctccaccac aactacccaa gcaaccccaa ctgattggaa gacctccgtc
     7741 agcctctcaa actccaatcc cctccagtcc actgcaaatt tccatgactt ccatccagaa
     7801 cagtctacct ccacagttac tccaataccc gtgtgatcag tgtactatag cattcccgac
     7861 cctggaactt tggaaggaac accaacacat gcacttcctg gctgctcaaa accaattcct
     7921 ccactctcca ttcttggaaa ggcccatgga catgccctac atgatatttg accccaacaa
     7981 tccactgatg actggacagc tcctggggag ctcgctcact caaatgccac cacaggccag
     8041 tactgctcac actacggccc ctgcgagtgt tgctgcttcc cttaaaagga aattggatga
     8101 taaagaagat aataattgca gtgagaagga gggcggaaat agcggtgaag atcaacaccg
     8161 agataaacgc ttgagaacca ccatcacgcc tgagcaactc gaaatactct atgaaaagta
     8221 cttgctggat tctaatccta cccggaaaat gctcgatcac attgcgcggg aagtggggct
     8281 gaagaagaga gtggtccaag tctggttcca gaacacgcgg gctcgagaaa ggaaagggca
     8341 gttccgtgct gtgggtcctg cccagtctca taaacggtgt ccattctgca gagctctgtt
     8401 taaagcaaag tcagccttag aaagccacat tcgctctcgc cactggaatg aggggaagca
     8461 ggcaggttat agcttgccac caagcccttt aatatccaca gaggatgggg gagagagccc
     8521 acagaaatac atttactttg attacccatc tttgccatta actaaaattg atctatcgag
     8581 tgagaatgaa ttggcctcca cagtctcaac acctgttagt aaaacagcag aactgtctcc
     8641 gaagaatctt ttaagtcctt cttctttcaa agcagaatgt cccgaggatg tagagaatct
     8701 aaatgcccct tcagctgacg ctgggtatga tcagaataaa actgactttg atgagacatc
     8761 atccattaat acagccatca gtgacgcaac cacaggggat gagggggcag cagacatgga
     8821 aaacacggga ggttctgaag aggtgaaacc agctttgtcc cctaaagaaa ccaaaagtct
     8881 tgactctttg ccaaaagcag gaaccacacc caccacagag gtctgtgatg acaaatttct
     8941 cttttctctc acaagtccat caatccactt caatgacaaa gatggtgacc acgaccaaag
     9001 cttctacatc accgatgacc ctgacgacaa tgctgaccgc agcgaaacat ctagcatagc
     9061 tgaccccagc tcaccaaatc cattcgggtc tagcaacccc tttaaatcca aaagcagtga
     9121 tcggcctggt cacaagcgct tcagaaccca gatgagcaat cttcaactga aggtcctcaa
     9181 ggcttgcttc agtgactatc ggactccaac catgcaagaa tgtgaaatgc tgggcaatga
     9241 gatcggtctg cccaaacgag tggtgcaggt gtggtttcag aatgccaggg caaaggaaaa
     9301 gaaatttaaa atcaacatag gaaagccgtt tatgatcaat caaagtggga cggatggcac
     9361 caagccagag tgtaccctct gtggagtgaa gtactctgcc cgcttgtcca tccgagatca
     9421 tattttttcc aaacagcata tttccaaagt gagggagacc gtaggcagtc agcttgaccg
     9481 ggaaaaagat taccttgctc ctaccaccgt tcgacagctg atggcccaac aagaactgga
     9541 ccgtataaag aaagcatccg atgtactggg cctaacagta cagcagccag gcatcacaga
     9601 caactgctca ctccatggga tcagcttgcc agcagcctac cctggactcc ctggccttcc
     9661 tccagtcatt ctccctggga tgaatggtcc ttcctccttg ccgggatttc cacaaaattc
     9721 aaacacatta acacctcctg gtgcaggcat gcttgggttt cctagttcag ctacttcgtc
     9781 tcctgccttg tctctcagca gtgcccccac caaatctttg ctgcagactc caccacctcc
     9841 accaccacca ccaccaccac ctcctcctcc tccatcctct ctgtcaggac agcagaccga
     9901 gccacagaac aaagaaccgg agaaaaagca aactaagcca aacaaggtga aaaaaatcaa
     9961 ggaggaggaa tcagaggcca tcaaacccga aaagcatccc aaaaaagagg aaaaaatctc
    10021 atctgctctt tcagtattgg gtaaagtagt aggggaaaca cacatggacc ctactcaatt
    10081 gcaggccttg cagaatgcca ttgctggtga ccccacatcc tttataggag gacagttctt
    10141 gccatatttt atccctgggt ttgcatccta ttttacacct cagctccctg gaacagtgca
    10201 gggaggctac ctgccaccag tctgtggcat ggagagtctc tttccctatg gtcccgcagt
    10261 acctcagact ctggcggggc tgtccccagg ggcgctgcta caacagtacc aacagtatca
    10321 gcagagcctg caagattccc tacagaaaca gcaaaagcaa cagcaagaac agcagcagaa
    10381 accagttcct gccaagacag ccaaaggcga gggcgaccag ccgcagagct ccaacgaggc
    10441 ttcggaaacc aaggaagaga aaagtactgc tcccgaaagc acaaaagaag aagcccagtt
    10501 agattccaag actacagagt tttcagatac ttgtgtggtt ccattcgtca agtatgagtt
    10561 tatatgcaga aagtgccaga tgatgtttac tgacgaagac gccacagtaa accatcaaaa
    10621 gtccttctgt tatttcggtc agccgttgat agaccctcaa gagacagtgc ttcgcgtccc
    10681 ggtcagcaaa tatcagtgtc ttgcctgtga cctggctctc agtgggaatg aagcacttag
    10741 ccaacacctc cagtcaagct tgcacaaaga gaaaacaatc aaacaagcaa tgagaaatgc
    10801 caaagagcat gttagattat tacctcactc agtctgctcc cctcctccta acacctcatc
    10861 tacctcgccg tctgcagctt cttctaataa cacctacccc catctctctt gcttctccat
    10921 gaagtcctgg cctaatatcc ttttccaagc atctgccagg aaagctgctt cgtccccctc
    10981 ttctcctccc tccctctcct tgccttcaac ggttacctca agtttgtgca gcacctcagg
    11041 ggttcaaacc tcactaccca cagaaagttg ttcagatgag tctgacagtg agctgagcca
    11101 gaagctacaa gacttagata attctttgga agtgaaggct aagcctgctt ctggcctaga
    11161 tggtaatttc agtagtgtcc gaatggatat gttcagtgtg taggagtgaa gacaggatcc
    11221 cgtgcttaaa aaaaaaataa aaaataaata aaaattaaaa aaaaataaga ctttaactgc
    11281 agttccaaag cttctctaat ccaaaaatta cagtaccaaa tgattgactc aggattgttt
    11341 ttcccatatt gatatgctgg caatatagaa tggtatgtgg tgaagaggac tgatgcaggt
    11401 ggttgaatgc gcttgtaata tatgctaaaa tatggaaaag gaaaaaaata tctcacaagt
    11461 tctttcagaa cttgtttcaa gccaaaaact ctcaagacag aaaattgcac ctcagctggg
    11521 ttgatttccg aatgccagca tggacagtat gggaggacga tccggatgtt tcaaagagaa
    11581 cttctcttag tttagttagg tgtaattcag tagctttaaa ttctcaggtc agaacataac
    11641 atttctcatt tgttaaaagc agcaagaagc ctggtaaaac tgtgactttt ccccaaatgt
    11701 caatctttat tagaaagcat tttctaggtg tgtttagtgt gcaaagagac tttctaaccc
    11761 ttactggaca ccacacagct ccctgaactc acgctgcagg atagtacagt tttaccacag
    11821 agggactcta gagcaatgga gtcacgtgtc tgccctgtgt attgcagctt gtattgacac
    11881 aagctgtctt tacaccagtg tcatcccttt cttgtagaat atactaataa tctgtgccaa
    11941 ctctaccttc ccacttttac ctctgacatc attctttttt tccgaaagag gtaataattc
    12001 tagttttgat agactctgag gatcatgtga acaggacatt tttcatttgt gaatttaatg
    12061 ctatattgtc aaggtacttg cttgtgtctg aactctagtg cacttatgat tttgtagacc
    12121 atgtggaatt taataggacg ctttttgccc ctcctttctc tgtgtctagt gcagcaacag
    12181 tttggtctgc atctgttaga agtgtaactc ctaacaaccc aaagacctat ttagtaattg
    12241 gtgcataaat gaaggtagta ctgtatactt gaaactgttt aagtacaagt tgaacaaaaa
    12301 ttatgaaaag atatatttgc ttctcgggaa agcaaagaag ctgctttaaa aaaaattaaa
    12361 aggggactaa aaatttgttt tgtataaaga ggttagccct gcccacgtag gactgaattc
    12421 agtgatatcc ctatacactg ccaattagtg gataggttat tgtacttcca ttcatactct
    12481 gggcacttgt gttaaattgt tctgttacac acttttgtct aacctgtttt gttttttatc
    12541 atatatgcat taaaagtatt atctttatca acatttgctg ctattgtgtt aacatttttg
    12601 ttttgcttgc catgaggtcc catttccacc tcccagtgaa ttgacttata aatcgctatg
    12661 cttttcctgt tttgttttgt ttttttcttt ctgttgctgt ggaacttaaa gaatgtgaaa
    12721 gctgtcaaaa gatattttcg gaatcacttt tgtgtttggt acagtaaaac aatgtgattc
    12781 attccaaagt aacagaaggt tatttgtaag aaagttaaag gcttgtgaac aaagaaagct
    12841 aagctgttgt acatattgta gttggctgtg catggtacaa atttattaat atgaagaaat
    12901 gcaaaatgta ttgcttttga tatttctatt ctgagatgaa caagtagcat gtaatgcaac
    12961 tgtttgacag tttaactcga atcatgcttc aaactgtttt aatgatcaaa ccaagtcact
    13021 gttcatttca tcttcttgta cagtttttgt ttgggtaatg atcacagcaa tctttataca
    13081 ttttatgtga actctttaat gtctttaatt tggatttttg ttttttcgta ctttaacatt
    13141 tattttaatc ctgaagacac ttttttgatt gtgtttcgta agagacaaca tggcctccta
    13201 aggtgcaatc ctgccgctat agtgagctaa tgtcctgaat ccaaaggctt cagaaaattg
    13261 cttttgcctt tttcatgaat gttaagcagc agcattgtga gatcgatctg tcctggcagt
    13321 taacacgatg tgcaacagag tgttagcatg gaacagaacg tctctcacaa aacaaaggac
    13381 cgttttacaa aggatgattc cgacaatgtg tcgacataaa ctttgacaac tgcacagcag
    13441 ccaaaaaaag aaaaaaatac ctttaactgg atggacgttg ttagggtgag aaataaaagg
    13501 acagcctcca aaggttgaga gcaagaatcg tttttttctt ggatatcaaa gggattatca
    13561 cagcgcaatc attgtctaca acaacatgta cactcaatgc ctgggttaca taggaaacgc
    13621 accctgaggt tttaataaag cccctatggc tataacttta aataaactaa accaaaaatg
    13681 ttattgatgt tttatataga gagagtagga tcattagttt ttgttactgt aatgtttgat
    13741 gtctcaaatg caccgtatta cggtaataac atggttttga aaactttctg tttttatttt
    13801 gtcacagagc tgttgtcata gttgaaatga tgtttattgt agatggtatt tgaacttatt
    13861 cttctggaaa tagttcatca agtatgtttg ttgctcattg tgatacatta aaaactgtat
    13921 ctgcata
//
