LOCUS       NM_001414958            4465 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus zinc finger and AT hook domain containing (Zfat),
            transcript variant 1, mRNA.
ACCESSION   NM_001414958 XM_017594960
VERSION     NM_001414958.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4465)
  AUTHORS   Tsunoda,T., Takashima,Y., Tanaka,Y., Fujimoto,T., Doi,K.,
            Hirose,Y., Koyanagi,M., Yoshida,Y., Okamura,T., Kuroki,M.,
            Sasazuki,T. and Shirasawa,S.
  TITLE     Immune-related zinc finger gene ZFAT is an essential
            transcriptional regulator for hematopoietic differentiation in
            blood islands
  JOURNAL   Proc Natl Acad Sci U S A 107 (32), 14199-14204 (2010)
   PUBMED   20660741
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000007.1.
            
            On Dec 16, 2022 this sequence version replaced XM_017594960.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.27703.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-197               JAXUCZ010000007.1  101943041-101943237 c
            198-374             JAXUCZ010000007.1  101909664-101909840 c
            375-623             JAXUCZ010000007.1  101897769-101898017 c
            624-809             JAXUCZ010000007.1  101873785-101873970 c
            810-960             JAXUCZ010000007.1  101871366-101871516 c
            961-2399            JAXUCZ010000007.1  101866521-101867959 c
            2400-2632           JAXUCZ010000007.1  101865516-101865748 c
            2633-2720           JAXUCZ010000007.1  101861148-101861235 c
            2721-2870           JAXUCZ010000007.1  101859734-101859883 c
            2871-3044           JAXUCZ010000007.1  101856879-101857052 c
            3045-3133           JAXUCZ010000007.1  101838976-101839064 c
            3134-3272           JAXUCZ010000007.1  101809904-101810042 c
            3273-3358           JAXUCZ010000007.1  101801156-101801241 c
            3359-3482           JAXUCZ010000007.1  101795922-101796045 c
            3483-3613           JAXUCZ010000007.1  101793159-101793289 c
            3614-4465           JAXUCZ010000007.1  101775916-101776767 c
FEATURES             Location/Qualifiers
     source          1..4465
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q34"
     gene            1..4465
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /note="zinc finger and AT hook domain containing"
                     /db_xref="GeneID:362925"
                     /db_xref="RGD:1310886"
     exon            1..197
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     CDS             179..3853
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /note="isoform 1 is encoded by transcript variant 1; zinc
                     finger protein 406; ZFAT zinc finger 1; zinc finger
                     protein ZFAT"
                     /codon_start=1
                     /product="zinc finger protein ZFAT isoform 1"
                     /protein_id="NP_001401887.1"
                     /db_xref="GeneID:362925"
                     /db_xref="RGD:1310886"
                     /translation="METRAAENTAIFMCKCCNLFSPNQSELVTHVSEKHGEEGVNVDD
                     VIIPLRPLNTPENPNPSKGGDEFLVMKRKRGRPKGSTKKPSTEEEVVENLVSPIEDGP
                     LAPEEGSRLAPSSLECSKCCRKFSNTRQLRKHICIIVLNLGEEGDAGNESDLDLEKTY
                     KEDDREKTSKRPRAQKTEKVQKISGKEAGQLSGAKKPIISVVLTAHEAIPGATKIIPV
                     EAGPPETGAPPPETTAADLVPRRGYQEYAIQQTPYEQPMKSSRLGPTQLKIFTCEYCN
                     KVFKFKHSLQAHLRIHTNEKPYKCSQCSYASAIKANLNVHLRKHTGEKFACDYCSFTC
                     LSKGHLKVHIERVHKKIKQHCRFCKKKYSDVKNLIKHIRDMHDPQDKKVKEALDELRL
                     MTREGKRQLLYDCHICERKFKNELDRDRHMLVHGDKWPFACELCGHGATKYQALELHV
                     RKHPFVYVCAICLKKFVSSIRLRSHIREVHGAAQETLVFTSSINQSFCLLEPGGDIQQ
                     EALGNQLPLAAEEFVCPEIDVRKGEVCPGEAQPEVGLRELEAPGEACAPAVPLANPQS
                     VSVSLSPCKLETTVVNSDLNSLGVVSDDFLLKTDTSSAEPHAAAELTSDTQHRGSAQT
                     QGEEVTLLLAKAKSTGPDSESPPSGGQNVGALPASESDSNRCLRANPAETSDLLPTVA
                     DGGDLGVCQPDSCTSSSEHHPGSTAFMKVLDSLQKKQMNTSLCERIRKVYGDLECEYC
                     GKLFWYQVHFDMHVRTHTREHLYYCSQCHYSSITKNCLKRHVIQKHSNILLKCPTDGC
                     DYSTPDKYKLQAHLKVHTELDKRSYSCPVCEKSFSEDRLIKSHIKTNHPEVSMNTISE
                     VLGRRVQLKGLIGKRAMKCPYCDFYFMKNGSDLQRHIWAHEGVKPFKCSLCEYATRSK
                     SNLKAHMNRHSTEKTHLCDMCGKKFKSKGTLKSHKLLHTSDGKQFKCTVCDYTAAQKP
                     QLLRHMEQHASFKPFRCAHCHYSCNISGSLKRHYNRKHPNEEYANVGSGELAAEALIQ
                     QGGLKCPVCSFVYGTKWEFNRHLKNKHGLKPATETPEEPSTQYLYITEAEDVQGTQAA
                     VAALQDLRYTSESGDRLDPTAVNILQQIIELGSETHDAAAVASVVAMAPGTVTVVKQV
                     TDEEPNSNHTVMIQETLQQASVELAEQHHLVVSSDDVEGIETVTVYTQGGEASEFIVY
                     VQEAVQPMEEQVGEQPAPEL"
     exon            198..374
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            375..623
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            624..809
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            810..960
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            961..2399
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            2400..2632
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            2633..2720
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            2721..2870
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            2871..3044
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3045..3133
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3134..3272
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3273..3358
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3359..3482
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3483..3613
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
     exon            3614..4465
                     /gene="Zfat"
                     /gene_synonym="Zfat1; Zfp406"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagactcca tccgccatgt tggatgccgc agattcgcca taacctctcc ggctctttcc
       61 ctaaaaaaat aaaaataaag agcgaagttt cctcagggtg tccgaccttc tcgctcggca
      121 cgggagggag ccaggaagag cccgaggctt ttttttcctc cgtcgtgggg gcgttgccat
      181 ggagacgcgg gcggcagaaa acacagccat cttcatgtgt aaatgctgta atcttttctc
      241 gccaaatcag tcagaactcg tgacccacgt ttctgagaag catggggaag aaggggtcaa
      301 tgtggatgat gtcatcattc ccctcaggcc tctgaatact ccagaaaacc ccaacccaag
      361 caagggtgga gatgagtttt tggttatgaa gagaaagaga ggcaggccta agggttccac
      421 aaagaagccc agcactgaag aggaagtagt agaaaacctc gtgagcccca ttgaggatgg
      481 tcccctggct ccagaagaag ggagcagact ggcccctagc agcttggagt gtagcaagtg
      541 ctgccggaag ttttccaaca cgcgccagct gcgaaagcac atctgcatca ttgtgctgaa
      601 cctgggtgaa gagggagatg caggtaacga gtcagacctt gatctagaaa agacatacaa
      661 agaagatgat cgagaaaaaa cttcaaaaag accccgggct cagaaaacag agaaagtcca
      721 gaagatctca ggaaaagagg cagggcagct ttctggagcg aagaaaccta tcatcagcgt
      781 ggtcttaact gctcatgaag caattccagg tgctaccaag attattccag tggaggctgg
      841 gccccctgaa acaggagcac cccctcccga gaccactgca gcagacctgg tgccacggag
      901 agggtaccaa gaatacgcca ttcagcagac cccatatgag cagcccatga agtcaagcag
      961 gttaggtccc acccagttga agatcttcac ttgtgaatac tgcaacaagg tgttcaagtt
     1021 caagcactca ctgcaggccc acttgaggat ccacactaat gagaagccat acaagtgctc
     1081 ccagtgcagc tatgccagcg ccatcaaggc taacctcaat gttcacttgc gcaagcacac
     1141 tggagagaag tttgcctgtg actattgctc cttcacctgc ctcagcaaag gccacctcaa
     1201 ggtacacatt gagcgagtac acaagaaaat caaacagcat tgccgcttct gcaagaagaa
     1261 atactcagat gtcaagaacc tcatcaagca catccgggac atgcatgacc cacaggacaa
     1321 gaaggtcaag gaggccttag atgagctacg cctaatgacg agggaaggca agcggcagct
     1381 gctttatgac tgtcatatct gtgagcgcaa gttcaagaat gagttagacc gagaccgcca
     1441 catgctggtt catggtgaca agtggccctt tgcttgtgag ctctgtggcc atggggccac
     1501 taaataccag gccttggaac tgcatgtcag gaagcatccc tttgtgtatg tctgtgctat
     1561 atgtctcaag aaatttgtca gctcaatcag gctgcgctcc catatccgag aggtgcatgg
     1621 ggcggcccag gagaccttgg tttttactag ctccatcaac cagagtttct gcctcctgga
     1681 gcctggtggg gatatccagc aggaagcctt gggaaaccag ctaccactgg cagctgagga
     1741 atttgtgtgt ccagaaattg atgtacgtaa gggggaggtt tgtcctgggg aagctcagcc
     1801 tgaggtgggg ctgagggagt tggaggcccc tggagaagca tgtgccccag ccgtgccctt
     1861 ggccaacccc cagagtgtca gtgtttccct gtccccctgc aaactggaaa ccactgtggt
     1921 caattccgac ctcaactctc ttggagtggt ttcagatgat tttttactga aaactgatac
     1981 ctcttctgct gagcctcatg ctgctgctga gctaacctcg gacacacagc atcgaggctc
     2041 agcccagact cagggtgaag aagtcacact gctgctggcc aaggccaaaa gtactggacc
     2101 agactcagag agtcctccaa gtggagggca gaatgtgggt gctctgccag ccagtgaatc
     2161 tgactctaac aggtgtctca gggcaaaccc agcagagacc tcagacctcc ttcctacagt
     2221 ggctgatgga ggagacctcg gtgtgtgcca gcctgactct tgcacgtcgt cctctgagca
     2281 ccaccctggc agcacagcat tcatgaaggt cctagacagt ctccagaaga agcagatgaa
     2341 caccagtctt tgcgagcgga tccggaaggt ttatggagac ctggagtgtg aatactgtgg
     2401 caaacttttt tggtaccaag tgcattttga catgcatgtc cgcacccaca cccgggaaca
     2461 tctgtattat tgctcccagt gtcactactc ttccatcacc aaaaactgcc ttaaacgcca
     2521 tgtaattcag aaacacagta acatcttgct gaagtgtccc actgacggct gtgactactc
     2581 gactccagat aaatataagc tacaggccca ccttaaagtt cacacagagc tggacaaaag
     2641 gagttattct tgtcctgtat gtgaaaaatc tttttcagaa gaccgattga taaagtcaca
     2701 tatcaagact aatcatccag aggtctccat gaataccatt tctgaggttc ttgggagaag
     2761 agtccagctc aaagggctaa ttggaaagcg agccatgaag tgtccgtatt gcgatttcta
     2821 tttcatgaag aatggctcag accttcagcg gcacatctgg gctcacgagg gtgtgaagcc
     2881 cttcaaatgt tctttgtgtg agtatgcaac tcgtagcaag agcaacctca aagctcatat
     2941 gaatcgtcac agcactgaga agactcacct ctgtgacatg tgtggcaaga aattcaaatc
     3001 caaagggaca ttaaagagtc ataagctcct tcacacatct gatgggaagc aattcaagtg
     3061 cacggtgtgt gactacacag ctgcccagaa accacagctg ctgcgacaca tggagcagca
     3121 tgcctccttc aagcctttcc gctgcgctca ctgtcattat tcatgtaaca tctctggatc
     3181 tctgaaacgg cactacaaca ggaagcaccc caacgaggag tatgccaacg tgggcagcgg
     3241 ggagcttgca gctgaagccc tcatccaaca aggtggtctg aagtgtcctg tttgcagctt
     3301 tgtgtatgga accaaatggg agttcaacag acacttgaag aacaagcatg gcttgaagcc
     3361 agcgacagag actcccgagg agccctccac ccagtatctc tacatcaccg aggctgaaga
     3421 tgttcagggg acacaagcag ctgtagctgc acttcaggac ctgcgatata cctccgagag
     3481 tggtgatcga cttgacccca cagctgtgaa tatcctgcag cagatcattg aactgggttc
     3541 agagactcac gatgctgctg ccgtggcctc cgtggttgcc atggcgcctg ggacagtgac
     3601 tgttgtaaag caggtcaccg atgaggaacc caattccaac catacagtca tgatccagga
     3661 gactctgcag caggcctctg tggagttggc cgagcagcac catctggtgg tgtcctctga
     3721 tgacgtggag ggcattgaga cagtgacagt gtacacacag ggtggggagg cctcagagtt
     3781 catcgtgtac gtgcaagagg ctgtccagcc catggaggag caggtcgggg agcagccagc
     3841 cccagaactc tagagaatcc ctgcctcctt tggcagccag cctttgtggg cctgaagacc
     3901 tcctaaccca ccaggtccat ccctgctctt cttgcccact ggcccagata aatttctcca
     3961 tactgtcctc tgtgtggtca aagccagaga gtatcaccag cagtacagaa gcccagtcct
     4021 caatacaaat cacatcctga cccaggaccc tctgtttcca gaagacattt ccatcaactc
     4081 tcctgcccta ccccttactt gcttcaagac tcagagactc ctctccccat cagcatcttc
     4141 tttcaacccc agccctttgg gtccctaccc tccacccttg gtacacatcc ttggctgggc
     4201 ccactgtgct gtctgtgaga gggagacaga cattacacag caagtggcct tatgtctttt
     4261 gagttaaccc tgggtagggt gggcagaacc atccaagcat tcactgggcc ctgccctcct
     4321 cagcgcaggg acactggaaa caaatcagtg acccatggtc ctctatcaca agggcccagc
     4381 ttggaattct tttctctttt aaaataaatg cattttttct ttcaccccct cccccccatt
     4441 cagggaggtg ggtgagatta aagca
//
