LOCUS       NM_213627               1984 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zinc finger DHHC-type palmitoyltransferase 23
            (Zdhhc23), mRNA.
ACCESSION   NM_213627 XM_344020
VERSION     NM_213627.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1984)
  AUTHORS   Tian,L., McClafferty,H., Knaus,H.G., Ruth,P. and Shipston,M.J.
  TITLE     Distinct acyl protein transferases and thioesterases control
            surface expression of calcium-activated potassium channels
  JOURNAL   J Biol Chem 287 (18), 14718-14725 (2012)
   PUBMED   22399288
REFERENCE   2  (bases 1 to 1984)
  AUTHORS   Chen,M.L., Cheng,C., Lv,Q.S., Guo,Z.Q., Gao,Y., Gao,S.F., Li,X.,
            Niu,S.Q., Shi,S.X. and Shen,A.G.
  TITLE     Altered gene expression of NIDD in dorsal root ganglia and spinal
            cord of rats with neuropathic or inflammatory pain
  JOURNAL   J Mol Histol 39 (2), 125-133 (2008)
   PUBMED   17899403
  REMARK    GeneRIF: NIDD mRNA was predominantly expressed in nociceptive
            neurons and in neurons of the spinal dorsal horn and the number of
            NIDD-positive neurons in the corresponding dorsal root ganglia or
            spinal cord increased following induction of chronic hyperalgesia.
REFERENCE   3  (bases 1 to 1984)
  AUTHORS   Cheng,C., Chen,M., Shi,S., Gao,S., Niu,S., Li,X., Liu,H., Qin,Y.
            and Shen,A.
  TITLE     Effect of peripheral axotomy on gene expression of NIDD in rat
            neural tissues
  JOURNAL   J Mol Neurosci 32 (3), 199-206 (2007)
   PUBMED   17873365
  REMARK    GeneRIF: NIDD gene expression may be involved in the different
            pathological conditions including nerve regeneration, neuron loss
            or survival, and even pain processes.
REFERENCE   4  (bases 1 to 1984)
  AUTHORS   Saitoh,F., Tian,Q.B., Okano,A., Sakagami,H., Kondo,H. and Suzuki,T.
  TITLE     NIDD, a novel DHHC-containing protein, targets neuronal
            nitric-oxide synthase (nNOS) to the synaptic membrane through a
            PDZ-dependent interaction and regulates nNOS activity
  JOURNAL   J Biol Chem 279 (28), 29461-29468 (2004)
   PUBMED   15105416
  REMARK    GeneRIF: These results suggest that NIDD plays an important role in
            the regulation of the nitric oxide signaling pathway at
            postsynaptic sites through targeting of nueronal nitric oxide
            synthase to the postsynaptic membrane.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY886538.1.
            
            On Jun 10, 2007 this sequence version replaced NM_213627.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY886538.1, AB098078.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132262, SAMD00132263
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1984
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..1984
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /note="zinc finger DHHC-type palmitoyltransferase 23"
                     /db_xref="GeneID:363783"
                     /db_xref="RGD:1303254"
     exon            1..258
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..1405
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /EC_number="2.3.1.225"
                     /note="probable palmitoyltransferase ZDHHC23;
                     membrane-associated DHHC23 zinc finger protein;
                     nNOS-intereacting DHHC-containing Dem protein-L; DHHC-23;
                     zinc finger DHHC domain-containing protein 23;
                     NNOS-interacting DHHC domain-containing protein with
                     dendritic mRNA; zinc finger, DHHC domain containing 23;
                     zinc finger, DHHC-type containing 23"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC23"
                     /protein_id="NP_998792.2"
                     /db_xref="GeneID:363783"
                     /db_xref="RGD:1303254"
                     /translation="MKPVKKKKTEEPELEPLCCCEYIDRNGEKNHVAACLCDCQDLDE
                     GCDRWLTCKSLRPETCERITDTISDRLRIPWLRGAKKVNISILPPLVLLPVLLRVASW
                     HFLLGVVVLTSLPMLALWYYYLTHRRKEQTLFFLSLGLFSLGYMYYVFLQEVVPQGHV
                     GPAQLALLTCGLFLILVALYRAKKNPGYLSNPACNDKSPSNSQIECPIKKGQEKTKGF
                     PGTDTSGSLNNRTLKDDAKGSSRVGLDSPAKSKEDWCAKCQLVRPARAWHCRICGICV
                     RRMDHHCVWINSCVGESNHQAFILALSIFLLTSVYGISLTLNTICRDRSLFTALFYCP
                     GVYANYSSALSFTCVWYSVIITAGMAYIFLIQLINISYNVTEREVQQALRQKTGRRLL
                     CGLIVDTGQYNRGFLRNWLQFSTLGTRTVHTPAEDIV"
     exon            259..969
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1137
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /inference="alignment:Splign:2.1.0"
     exon            1138..1984
                     /gene="Zdhhc23"
                     /gene_synonym="DHHC23; nidd"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagaagtgaa gatgtgttta caggatgtga gttgagttct ctccaccttt accttccgag
       61 agctgcttct tatgcctcat ggtgacaggt acaaatcttt acgctaaaag gcaatatgaa
      121 gccagtaaaa aaaaagaaaa ccgaagagcc tgaattggag cccctgtgtt gctgtgagta
      181 catagatcga aatggggaaa agaaccacgt ggctgcctgt ttgtgtgatt gtcaggacct
      241 cgatgaaggc tgtgacagat ggcttacctg taaatcgctt cggccggaga cgtgtgagag
      301 aatcacggat acgatttctg atcgcctccg aattccttgg ctccgaggag ccaaaaaagt
      361 caatatcagc atcctccccc cactcgtgct cttgccggtt ctgctccgcg tggcttcctg
      421 gcacttcctg ctgggggtgg tggttctgac ctccctgccc atgctggcac tgtggtacta
      481 ctacctcact cacagaagga aagagcagac gctgtttttc ttgagcctcg gtctgttctc
      541 cctgggctac atgtactatg tgttcttgca ggaagtggtc ccccaagggc acgtagggcc
      601 cgctcagctg gcccttctca cctgcgggtt atttctgata ctcgtagcct tgtaccgagc
      661 caagaagaat ccaggctacc tcagcaaccc agcatgcaat gacaaatccc ccagcaacag
      721 ccaaatcgaa tgcccgatca aaaaagggca ggagaagacc aaagggttcc ccggcacaga
      781 tacctcgggg agccttaaca accgcacact gaaggacgat gctaagggct cctccagggt
      841 ggggcttgac agccccgcca aatcgaagga agactggtgt gccaagtgcc agctagtgcg
      901 gcccgcccgg gcgtggcatt gccggatatg cggtatctgt gtgaggagaa tggatcacca
      961 ttgtgtctgg ataaacagct gcgtcggaga atcaaaccat caagcgttta tacttgctct
     1021 ttccatcttc ttgctcactt cggtttacgg aatatcgctg accttgaaca ccatctgtag
     1081 ggacagaagc ctcttcacag ccctcttcta ctgtcctgga gtttacgcta attacagctc
     1141 agctctatcc ttcacctgcg tgtggtactc ggtgatcatc acagccggca tggcctacat
     1201 cttcctcatc cagctgataa acatcagcta caatgtgacg gagagggaag tgcagcaggc
     1261 ccttcggcag aagacggggc gccggctcct ctgtgggctc attgtggaca cgggccagta
     1321 caacaggggc ttcctgcgca actggctcca gttctccacc ctaggcacac gcacagtcca
     1381 cacccctgcc gaggacattg tctaagtgcc ttccatgcgg ccctgcggga cattcctcgc
     1441 tgtccttcct gttcacgtca gtatccatgc aggactcatc tccaccgccc acttctcgga
     1501 agtactgccg agctacgctc aggtttggag aggaccgaag aaagggtaac ttcttctgcc
     1561 tttataactc atgggagttt tactgaagca gcaagagtag ccattccttt cctgtcccct
     1621 tgctgactca ggcaccagaa gctgcaaaga ggctgtggtc acacaaactg tccatatgag
     1681 gaaggaagtt agttagaatg aggagtgttc ctagtcctcc gttccatttc taatagccat
     1741 gtgacccctc ggtcgagtca ctttcccaag tctcaggttc atctgtgtgg gggcttctgc
     1801 tgcctggcta cctcatggag cagccatgat ggccacctga ggagggctgt ggagttcaac
     1861 tccagcactc gggggagtca ggcattatta gaaaatgcct aggactgaag cagactgctc
     1921 ataggtcaga atattgaagc caatactgtt aagacaatca gtttgtacag ttaaggaaat
     1981 tctc
//
