LOCUS       NM_001039009            3485 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus zinc finger DHHC-type palmitoyltransferase 21
            (Zdhhc21), mRNA.
ACCESSION   NM_001039009 XM_233110
VERSION     NM_001039009.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3485)
  AUTHORS   Ohno,Y., Kashio,A., Ogata,R., Ishitomi,A., Yamazaki,Y. and
            Kihara,A.
  TITLE     Analysis of substrate specificity of human DHHC protein
            acyltransferases using a yeast expression system
  JOURNAL   Mol Biol Cell 23 (23), 4543-4551 (2012)
   PUBMED   23034182
REFERENCE   2  (bases 1 to 3485)
  AUTHORS   Pedram,A., Razandi,M., Deschenes,R.J. and Levin,E.R.
  TITLE     DHHC-7 and -21 are palmitoylacyltransferases for sex steroid
            receptors
  JOURNAL   Mol Biol Cell 23 (1), 188-199 (2012)
   PUBMED   22031296
REFERENCE   3  (bases 1 to 3485)
  AUTHORS   Choi,J.W., Sutor,S.L., Lindquist,L., Evans,G.L., Madden,B.J.,
            Bergen,H.R. 3rd, Hefferan,T.E., Yaszemski,M.J. and Bram,R.J.
  TITLE     Severe osteogenesis imperfecta in cyclophilin B-deficient mice
  JOURNAL   PLoS Genet 5 (12), e1000750 (2009)
   PUBMED   19997487
REFERENCE   4  (bases 1 to 3485)
  AUTHORS   Mill,P., Lee,A.W., Fukata,Y., Tsutsumi,R., Fukata,M., Keighren,M.,
            Porter,R.M., McKie,L., Smyth,I. and Jackson,I.J.
  TITLE     Palmitoylation regulates epidermal homeostasis and hair follicle
            differentiation
  JOURNAL   PLoS Genet 5 (11), e1000748 (2009)
   PUBMED   19956733
REFERENCE   5  (bases 1 to 3485)
  AUTHORS   Ohno,Y., Kihara,A., Sano,T. and Igarashi,Y.
  TITLE     Intracellular localization and tissue-specific distribution of
            human and yeast DHHC cysteine-rich domain-containing proteins
  JOURNAL   Biochim Biophys Acta 1761 (4), 474-483 (2006)
   PUBMED   16647879
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY886536.1.
            
            [WARNING] On Mar 19, 2025 this sequence was replaced by
            NM_001039009.2.
            
            On Jan 12, 2006 this sequence version replaced XM_233110.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY886536.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3485
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q31"
     gene            1..3485
                     /gene="Zdhhc21"
                     /note="zinc finger DHHC-type palmitoyltransferase 21"
                     /db_xref="GeneID:298184"
                     /db_xref="RGD:1305750"
     exon            1..148
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            149..346
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     CDS             193..990
                     /gene="Zdhhc21"
                     /EC_number="2.3.1.225"
                     /note="probable palmitoyltransferase ZDHHC21; zinc finger,
                     DHHC domain containing 21; zinc finger, DHHC-type
                     containing 21"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC21"
                     /protein_id="NP_001034098.1"
                     /db_xref="GeneID:298184"
                     /db_xref="RGD:1305750"
                     /translation="MGLRIHFVVDPHGWCCMGLIVFVWLYNIVIIPKIVLFPHYEEGH
                     IPGILIIIFYGISIFCLVALVRASLTDPGRLPENPKIPHAERELWELCNKCNLMRPKR
                     SHHCSRCGHCVRRMDHHCPWINNCVGEDNHWLFLQLCFYTELLTCYALMFSFCHYYYF
                     LPLKTRNLDLFVVRHELAIMRLAAFMGITMLVGITGLFYTQLIGIITDTTSIEKMSNC
                     CEEISRPRKPWQQTFSEVFGTRWKILWFIPFRQRQPLRVPYHFANHV"
     exon            347..445
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            446..557
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            558..696
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            697..813
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            814..857
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
     exon            858..3468
                     /gene="Zdhhc21"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtactcata aagaactgtt attgaagaga ggcccatatg atggcacacg aaatggaaag
       61 aaagaaagaa aagaatgact gaagaagata gcacttctaa atgcaagtgc cagaaaaatc
      121 acagctcatc tcagtgaatt tgcaagtgga ttgtcttccc tgtgggttgg caggcagttt
      181 taggactgca gaatgggtct tcggattcac tttgttgttg accctcatgg ttggtgctgc
      241 atgggtttga ttgtctttgt ctggttatac aatattgtta taattcccaa aattgtcctc
      301 tttcctcact atgaagaagg acatattcct ggcattttaa taataatatt ctatggcatt
      361 tccatatttt gtctggttgc cttagtgagg gcctccctaa ctgatcctgg aagactccct
      421 gaaaatccca agatcccaca tgcagagcgg gagctgtggg agctgtgcaa caagtgtaac
      481 ttgatgaggc cgaagcgctc ccatcactgc agccgctgtg gccactgcgt gaggaggatg
      541 gaccaccact gtccctggat aaacaactgt gtgggtgagg acaaccactg gctttttctg
      601 cagttgtgct tctacactga gctgcttacc tgctacgctc tgatgttctc tttctgccat
      661 tattattatt tcctgccact gaaaacacgt aatttggacc tctttgttgt tcggcatgag
      721 ctggctatca tgaggctggc ggcctttatg ggcattacta tgttagtggg aatcactgga
      781 ctcttttata cacaactgat tggaatcatc acagatacaa catctattga aaaaatgtca
      841 aactgttgtg aagaaatatc gcggccccga aagccatggc agcagacctt ctcagaagtt
      901 tttggcactc gttggaagat cctgtggttc attcctttca ggcagaggca accactgaga
      961 gttccctacc actttgccaa tcacgtctaa acagatggat ggtgggcaca gatgggtcct
     1021 ccatgctgga aatgcatgtt acaggtttta tgagaataga actatgacag tcttcaagtc
     1081 aattaaaatc cacccaccaa tcttaggcat cataatgtgc cccaggcttc attttaatag
     1141 tgatcttgat cctgttgtgg ggctaataca tgatctatat ttaagtttta aaagcatgtt
     1201 tacttttaaa ttagccttgc accaggattc tttaaatgct tctgttacta gactcaaagg
     1261 cagtgattgg gataaaacaa tggtacatat gttttcttca gtactcggaa tattttaaaa
     1321 tctagtttat agaaatttga gatgttttat gtttaccttt aagcagtact aaccaaattt
     1381 gaatttaatt cttcaagttt acaaaagtgg atactttgtt atgtgtaaat tttccttttt
     1441 tgaatatcag ttaaaatgat gttactactt gcttttgatg tgctgcaggg tttttacagt
     1501 gcagtgagca gcaaggcgca gtggctgcct gggagcagct ctcggatgct cctctttcct
     1561 cctcagcagc cacagacgac accacgggtg tagcgcacca actactacct tactgtaaag
     1621 gaaagatgct tttctcttct gcagcagtca ttgattgcta atagaatatc tgctcccagg
     1681 agacatttgt gaccagtcag gcatatattc ctgttttacc ctaagattct aatgactgaa
     1741 gagggtagga agtttgcaat aattccagtt acttcttcaa gtgcagttat agtaaaaagc
     1801 agatgtttta aatgctcaac tggatggtgt gtaatgtaca gtgtaaagag gaaaactgct
     1861 tttaaagtat gtatactttt atttatctgc cactcgatct cactgtgcac attgaaggtt
     1921 tatatattgt agaatagatg ctgctcaact tatatcaaag tttaaagtag gtcacaaaat
     1981 tcatatacca gtaatcaccc cagttaaaat tgaatttgca ttggccagtt ctaatttgta
     2041 tcactctaga gaccttttat taatgtcagg atattattgt aatctacggt agtgatggtc
     2101 ccttaacaac atgggtctat tgtatgcaaa gacatttcat atgagttaat ttcttttcat
     2161 ttagaatact gaaaatgtat atgttttgtg tgcttggtga ccttttccct gaaaagaagt
     2221 tgaacaaatc taccattctt gaaccatata catacttttc ttataagagt tgtaaagtaa
     2281 ggaatcatag ctgggaaata ctgtggctag ttctttcaga tactgtaaat gtcttataag
     2341 atattctgag tagaataatc tctttgcaga aatattaata ccatattttc atgttctgat
     2401 aattatgttt gttatttaaa aacttagaag tggcagatgg aagcatttat tggtgctaag
     2461 acatatagca agtttaatat aagaaacatt tataaaggtt aggaaaccta caattagtat
     2521 gttttagtct aggcagaggg ttggatttat gtaagctgat tgactaagtt ggctggtgac
     2581 agttactaaa ggggagtggt gtatatctaa tgtggggagg taggcgtcga atgcctgcct
     2641 tcagctgtgt atgttcagtt cactcaagac ctggagcatc cacagcagag ccaagtgcag
     2701 gcccagtgtg gagctccgta actgcatgta cttctggagc agagtggctc tgacacagag
     2761 gcaatgggga gggatgatca cttccccatc tgggggtctg tggatttggt ttgcttatat
     2821 ttaccacttc tgggcacatc atcttccctt tctctttgtt ctccctggtc ctgacccgtc
     2881 tctgcagaat ttcctaagta gtcattggac ttaatacaca gtttgaccta cagaaatgct
     2941 attattgatg tatctataag aatctatatt gcagtgtacc tatatatact cacacagtat
     3001 tgtccaatgt atgtgtctga ccccacgagg ggtttgcaat ctatttagat tcctagggaa
     3061 aagcctgttg gccatttcct agggattaag ctcctatgtt ctttctgcgc cctcttttgg
     3121 ctaattgatg taattattct ggctctagag gcttttacta tcctgttagt gggttgtatc
     3181 gccaatctag gaacgtgcca gaggtgtaca cttataggaa catatgtata aaagtgtaaa
     3241 gttttataaa cattgaaaat ggatgtgtta ctgttggcga tgttccttct aggtgaagtg
     3301 ctcagctgta tgtatgtata ttcttgtata ctttttactg tcgctcacaa gttcagatta
     3361 gggtaagcta gttcttgatt ttactttaaa ccttattgtg gcaacttatt ttgttagcat
     3421 tataaaaact tacttaaaat actattttat taaaagacga aacatttaaa aaaaaaaaaa
     3481 aaaaa
//
