LOCUS       NM_001039339            2936 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus zinc finger DHHC-type palmitoyltransferase 18
            (Zdhhc18), mRNA.
ACCESSION   NM_001039339 XM_342931
VERSION     NM_001039339.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2936)
  AUTHORS   Ohno,Y., Kashio,A., Ogata,R., Ishitomi,A., Yamazaki,Y. and
            Kihara,A.
  TITLE     Analysis of substrate specificity of human DHHC protein
            acyltransferases using a yeast expression system
  JOURNAL   Mol Biol Cell 23 (23), 4543-4551 (2012)
   PUBMED   23034182
REFERENCE   2  (bases 1 to 2936)
  AUTHORS   Ohno,Y., Kihara,A., Sano,T. and Igarashi,Y.
  TITLE     Intracellular localization and tissue-specific distribution of
            human and yeast DHHC cysteine-rich domain-containing proteins
  JOURNAL   Biochim Biophys Acta 1761 (4), 474-483 (2006)
   PUBMED   16647879
REFERENCE   3  (bases 1 to 2936)
  AUTHORS   Fukata,M., Fukata,Y., Adesnik,H., Nicoll,R.A. and Bredt,D.S.
  TITLE     Identification of PSD-95 palmitoylating enzymes
  JOURNAL   Neuron 44 (6), 987-996 (2004)
   PUBMED   15603741
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000162.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001039339.3.
            
            On Mar 3, 2021 this sequence version replaced NM_001039339.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY886534.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132295,
                                           SAMD00132300 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-369               JACYVU010000162.1  60408845-60409213   c
            370-530             JACYVU010000162.1  60403017-60403177   c
            531-680             JACYVU010000162.1  60390572-60390721   c
            681-818             JACYVU010000162.1  60389025-60389162   c
            819-867             JACYVU010000162.1  60388601-60388649   c
            868-970             JACYVU010000162.1  60387868-60387970   c
            971-1083            JACYVU010000162.1  60385322-60385434   c
            1084-2936           JACYVU010000162.1  60382392-60384244   c
FEATURES             Location/Qualifiers
     source          1..2936
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2936
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /note="zinc finger DHHC-type palmitoyltransferase 18"
                     /db_xref="GeneID:362613"
                     /db_xref="RGD:1309334"
     exon            1..369
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..1201
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /EC_number="2.3.1.225"
                     /note="membrane-associated DHHC18 zinc finger protein;
                     zinc finger DHHC domain-containing protein 18; zinc
                     finger, DHHC domain containing 18; zinc finger, DHHC-type
                     containing 18"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC18"
                     /protein_id="NP_001034428.2"
                     /db_xref="GeneID:362613"
                     /db_xref="RGD:1309334"
                     /translation="MKDCEYQQISPGAAPPPASPGVHRPGPAAPPAPSPGPAPGAPRW
                     SVSGSGSGSGSGSGSLGRRPRRKWEVFPGRNRFYCGGRLMLAGHGGVFALTLLLILST
                     TILFFIFDCPYLARTLTLAIPIIAAILFFFVMSCLLQTSFTDPGILPRATICEAAALE
                     KQIDNTGSSTYRPPPRTREVMINGQMVKLKYCFTCKMFRPPRTSHCSVCDNCVERFDH
                     HCPWVGNCVGRRNYRFFYAFILSLSFLTAFIFACVVTHLTLLSQGSNFLSALKKTPAS
                     VLELVICFFSIWSILGLSGFHTYLVASNLTTNEDIKGSWSSKRGGEASVNPYSHKSII
                     TNCCAVLCGPLPPSLIDRRGFVQSDTVLPSPIRSDEPACGAKPDASMVGGHP"
     exon            370..530
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            531..680
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            681..818
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            819..867
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            868..970
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            971..1083
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
     exon            1084..2936
                     /gene="Zdhhc18"
                     /gene_synonym="DHHC-18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagcggccg ggcgcggagc cgaggcccgc ggccggccgc atgaaggact gcgagtatca
       61 gcagataagc cccggggccg ccccgccacc cgcttccccc ggggtgcatc gccccggccc
      121 cgccgcgccc cccgctccaa gccccgggcc cgcgcctggc gcgccgcgct ggagtgtcag
      181 cggcagcggc agtggcagcg gcagcggcag cgggagcctg ggccgccggc cgcggcgtaa
      241 gtgggaggtg ttcccgggcc gcaaccgctt ctactgcggc ggccgcctca tgctggccgg
      301 ccacggcggc gtcttcgcgc tcacgctgct gctcatcctc agcaccacca tcctcttctt
      361 catcttcgac tgtccctacc tggcccgcac actgaccctg gccatcccca tcatcgccgc
      421 catcctcttc ttcttcgtca tgagctgtct cctgcagacc agtttcactg accccggcat
      481 cctaccccgg gccaccatct gtgaggcagc tgccctggag aagcagatcg ataacacagg
      541 cagttccaca taccgcccgc cccctcggac tcgggaggtg atgatcaacg gacaaatggt
      601 gaagctcaag tattgcttca cctgtaagat gttccgtccg ccccggacct cacactgcag
      661 tgtctgtgac aactgtgtgg aacggtttga ccatcactgc ccttgggtgg gcaactgtgt
      721 ggggagacgg aattaccgct tcttttatgc ctttattctc tccctctcct tcctgacggc
      781 cttcatcttc gcctgcgtgg tcacccacct gaccctgctt tctcaaggaa gcaacttcct
      841 ctctgctcta aaaaagacac cagcaagtgt gctggagttg gtcatttgct tcttctcaat
      901 ctggtccatc ctgggcctct cagggttcca cacttacctc gtggcctcca acctgacaac
      961 taatgaagac atcaaagggt cttggtccag caagaggggt ggtgaggcct ctgtcaaccc
     1021 ctacagccat aaaagtatta tcaccaactg ctgtgctgtg ctctgtggcc cactgcctcc
     1081 cagcctgatc gaccggaggg gatttgtgca gtctgatact gtgctgccct cgcccatcag
     1141 aagtgatgag ccagcctgtg gagccaagcc agacgccagc atggtaggag gccaccccta
     1201 aatgtgactg agtgcttgcc acccaccgcc ctccacgcct gccgggaccc tccccgcctg
     1261 ccgggaccct ccccatgcca tctgagggaa gcagagctgc caaagactcc agtcttttcc
     1321 tatttatttc ccaccctgtg tggttttggt cttttttttt tttttttttt ttttttttga
     1381 actgtcctat ggctgtgccc tctgctccca aacctagggg cccacagttt aggccctagg
     1441 tccccagcag gtcagtgaca agaaagtcac agcctctgga ggccactaag gagaccatgc
     1501 caagtcactg cctgtgccca gggaggccca gcatgagtga gggtatggac tgaatgggca
     1561 gcctcccagc tggaggcctg ctcggactcc agtgagccag gggcttctgg aagaggccac
     1621 aggcaacgga tggggaccct ttccggaact gctttgtttt ggggactcct acattctgtt
     1681 tgatgaccac tggggttttt ttgggggggg gaggtgtgtg gagttagcca ataggataga
     1741 gccggggtac cggtagagag catgggcaga gggtgggaag cagcctgtgt cagaggaagc
     1801 caaacgagcc atccaggcct tcagaacctc agctcctgta gagtcgtggg caccacagta
     1861 ggaatgggga cctgactttc cccctgccca cggagactct ctaaaggatc cttttctgta
     1921 ccccccaatc cctcttccag gtcagggtta gaggcgggtg ggttagctca tgctggcaat
     1981 acttgaaacg ggtttattaa tgctgggtat tttgcacaat tttatagact tcttttttac
     2041 atagcccttt aaaaatagga gttaatgtgt tactgtccgt gtagtgccaa ggcaagggtt
     2101 ttcagaaggc taggtagttg aatacactta ttatagcaga tctagctgtg agggactgtg
     2161 tgtatgctca cacatgtgtc catgtatgcc tgtgacagat acagctgact cacgtgtccc
     2221 ctgggctgtt ccctttcccc attgccctga gtccagaagc agcccactgt atgggggact
     2281 gggtgggagg atgggcttta gtcccaagat ggagaccact ggctcctgcc ctcctgcctt
     2341 ccaccaaggc ctttaagact ctgccaccca gccctcaggc caggctccca gctgtgacct
     2401 gccccaacag gctgaggcta ggtgtggtgg gtggggtgat ggctctgggg agcggctgcc
     2461 ctgcaagcca caccccctcc taggtgttct gctttgagtg taggcctcag tgctagggat
     2521 tgaaccccag agcatttctg ctaatcagga atgagagagg aagggacaga gtggaccaga
     2581 ggcatgtgtg cttgtccaga agcctggagg atggccttct gctggcagct gtagtttcta
     2641 atcgaaatag tcctgttctc cttggccctt cgggtgggct gaagcccttg tgagtcataa
     2701 cataggaagt cactacagag tcccttcctt gctcccaagg ccagtgggtc cctggaagag
     2761 ctgggaagtg gtgggtgcca gggggcccct gggagatggc ttcagagccc tgggccatcc
     2821 tgagtggccc tgggaggtag ataggaaggg gctgggaggc tccctagctc accttttatt
     2881 tgagccagta ttccttgctc ctgcttgtaa taaagcctct tgtttttaag agctga
//
