LOCUS       NM_001401269            1870 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus zinc finger DHHC-type palmitoyltransferase 16
            (Zdhhc16), transcript variant 2, mRNA.
ACCESSION   NM_001401269 XM_006231403
VERSION     NM_001401269.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1870)
  AUTHORS   Abrami,L., Dallavilla,T., Sandoz,P.A., Demir,M., Kunz,B.,
            Savoglidis,G., Hatzimanikatis,V. and van der Goot,F.G.
  TITLE     Identification and dynamics of the human ZDHHC16-ZDHHC6
            palmitoylation cascade
  JOURNAL   Elife 6, e27826 (2017)
   PUBMED   28826475
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1870)
  AUTHORS   Cao,N., Li,J.K., Rao,Y.Q., Liu,H., Wu,J., Li,B., Zhao,P., Zeng,L.
            and Li,J.
  TITLE     A potential role for protein palmitoylation and zDHHC16 in DNA
            damage response
  JOURNAL   BMC Mol Biol 17 (1), 12 (2016)
   PUBMED   27159997
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1870)
  AUTHORS   Zhou,T., Li,J., Zhao,P., Liu,H., Jia,D., Jia,H., He,L., Cang,Y.,
            Boast,S., Chen,Y.H., Thibault,H., Scherrer-Crosbie,M., Goff,S.P.
            and Li,B.
  TITLE     Palmitoyl acyltransferase Aph2 in cardiac function and the
            development of cardiomyopathy
  JOURNAL   Proc Natl Acad Sci U S A 112 (51), 15666-15671 (2015)
   PUBMED   26644582
REFERENCE   4  (bases 1 to 1870)
  AUTHORS   Ohno,Y., Kashio,A., Ogata,R., Ishitomi,A., Yamazaki,Y. and
            Kihara,A.
  TITLE     Analysis of substrate specificity of human DHHC protein
            acyltransferases using a yeast expression system
  JOURNAL   Mol Biol Cell 23 (23), 4543-4551 (2012)
   PUBMED   23034182
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 7, 2022 this sequence version replaced XM_006231403.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22399489.719383.1,
                                           SRR22399492.2328179.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-181               JAXUCZ010000001.1  250694942-250695122
            182-326             JAXUCZ010000001.1  250696211-250696355
            327-574             JAXUCZ010000001.1  250699917-250700164
            575-769             JAXUCZ010000001.1  250700313-250700507
            770-858             JAXUCZ010000001.1  250700654-250700742
            859-887             JAXUCZ010000001.1  250701260-250701288
            888-1021            JAXUCZ010000001.1  250701819-250701952
            1022-1069           JAXUCZ010000001.1  250702075-250702122
            1070-1155           JAXUCZ010000001.1  250702857-250702942
            1156-1279           JAXUCZ010000001.1  250703700-250703823
            1280-1350           JAXUCZ010000001.1  250704104-250704174
            1351-1870           JAXUCZ010000001.1  250705800-250706319
FEATURES             Location/Qualifiers
     source          1..1870
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..1870
                     /gene="Zdhhc16"
                     /note="zinc finger DHHC-type palmitoyltransferase 16"
                     /db_xref="GeneID:654495"
                     /db_xref="RGD:1591893"
     exon            1..181
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            182..326
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            327..574
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     CDS             332..1465
                     /gene="Zdhhc16"
                     /EC_number="2.3.1.225"
                     /note="isoform 2 is encoded by transcript variant 2;
                     membrane-associated DHHC16 zinc finger protein; zinc
                     finger, DHHC domain containing 16; probable
                     palmitoyltransferase ZDHHC16; zinc finger, DHHC-type
                     containing 16"
                     /codon_start=1
                     /product="palmitoyltransferase ZDHHC16 isoform 2"
                     /protein_id="NP_001388198.1"
                     /db_xref="GeneID:654495"
                     /db_xref="RGD:1591893"
                     /translation="MRGQRSLLLGPARLCLRLLLLLGYRRRCPPLLRGLVQRWRYGKV
                     CLRSLLYNSFGGSDTAVDAAFEPVYWLVDNVIRWFGVVFVVLVIVLTGSIVAIAYLCV
                     LPLILRTYSVPRLCWHFFYSHWNLILIVFHYYQAITTPPGYPPQGRNDIATVSICKKC
                     IYPKPARTHHCSICNRCVLKMDHHCPWLNNCVGHYNHRYFFSFCFFMTLGCVYCSYGS
                     WDLFREAYAAIEKMKQLDKNKLQAIANQTYHQTPPPTFSFRERITHKSLVYLWFLCSS
                     VALALGALTMWHAVLISRGETSIERHINKKERRRLQAKGRVFRNPYNYGCLDNWKVFL
                     GVDTGRHWLTRVLLPSSHLPHGNGMSWDPPPWVTAHSASVMAV"
     exon            575..769
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            770..858
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            859..887
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            888..1021
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1069
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1070..1155
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1279
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1350
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1870
                     /gene="Zdhhc16"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctgggtgg tgatgggctg tccgcgggtc tcggtccgct ggctggcgct gcgggctcag
       61 ggccatggtg ggttagcctt agctcggccc ggcctgggtc ccgagctgga aggggaggca
      121 gtgagtggct gacagggaga cttggcctaa tctagctgat tgagaagctg gcaggaggca
      181 gaaagaatga gtgcagcaaa tcctttggtg tgatcacttt ggtaggagtg tctctgctgg
      241 cttctgtaga gctgtcggcc tttcctgttc tgcctctctc caggtcattc cttcaacaag
      301 tatttattga aacttctatg cgccaggagc catgcggggc cagcgaagtc tgctgttggg
      361 cccagcacgc ctctgcctgc gtctccttct gctcctgggc taccggcgtc gatgcccacc
      421 tctgctccgg ggcctggtac agcgctggcg ttatggcaag gtttgcctgc gctccctgct
      481 ctacaattcc tttgggggca gtgacactgc tgtcgatgct gcctttgagc ctgtctactg
      541 gctggtggac aatgtgatcc gctggttcgg agtggtgttt gtggtgctgg tgatcgtgct
      601 gaccgggtcc attgtggcca ttgcttatct gtgtgtccta cccctcatcc tgcgaaccta
      661 ttcggtacca cggctctgct ggcatttctt ctacagtcac tggaatctga tcctcatcgt
      721 cttccattac taccaggcca tcaccactcc tcctggatac ccaccccagg gcaggaatga
      781 cattgctact gtctccatct gtaagaagtg catttaccct aagccagcac gaacacacca
      841 ctgcagcatc tgtaataggt gtgtgctgaa gatggatcac cactgcccct ggctaaacaa
      901 ttgcgtgggc cactataacc atcgctactt cttctctttc tgcttcttca tgactctggg
      961 ctgtgtctac tgtagctacg gaagttggga ccttttccgg gaggcttatg ctgccatcga
     1021 gaaaatgaaa cagcttgaca agaacaaact acaggcgatt gccaaccaga cataccacca
     1081 gactccacca cctaccttct cctttcgaga aaggattact cacaagagtc ttgtctacct
     1141 ctggttcctg tgcagttctg tggccctggc cctgggtgcc ctaaccatgt ggcatgctgt
     1201 cctcatcagc cggggtgaga ctagcatcga aaggcatatc aacaagaagg agagacgccg
     1261 gctacaggcc aagggcagag tgtttaggaa tccttacaac tacggctgct tggacaactg
     1321 gaaggtgttc ctaggtgtgg acacaggaag gcattggctg acccgggtgc tgttaccttc
     1381 tagtcacctg cctcatggga atgggatgag ctgggatcct cctccctggg tgactgctca
     1441 ctcagcctct gtgatggccg tgtaagccac aacttgaaca ttgttcgatg tttattgtct
     1501 ttcaagagct tccaagggca gcttttcctg gaatccatga ccataagaac cattaggctg
     1561 ccttagagta ctacacaggg acaatcaaga gcaatcttct gccacctcag agcaagatgc
     1621 agtgtggagg aactcaatga ttgaagtccc tttactcagg caaataagtt ttagccccag
     1681 accaggagtc aggtaatgag ctctaggtca cagcactggg gctagacacc atttctttga
     1741 ctttgggaaa agatccatca ggtgtgttct ggcttcgcaa tgggataaag aacctaagcc
     1801 tattgccaag gtcactgcca tttctcacgt gctacggaag gagcgaaaat aaaggcattt
     1861 gatttgtaaa
//
