LOCUS       NM_001013216            2224 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus zinc finger and BTB domain containing 48
            (Zbtb48), mRNA.
ACCESSION   NM_001013216 XM_342985
VERSION     NM_001013216.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2224)
  AUTHORS   Jahn A, Rane G, Paszkowski-Rogacz M, Sayols S, Bluhm A, Han CT,
            Draskovic I, Londono-Vallejo JA, Kumar AP, Buchholz F, Butter F and
            Kappei D.
  TITLE     ZBTB48 is both a vertebrate telomere-binding protein and a
            transcriptional activator
  JOURNAL   EMBO Rep 18 (6), 929-946 (2017)
   PUBMED   28500257
REFERENCE   2  (bases 1 to 2224)
  AUTHORS   Li JS, Miralles Fuste J, Simavorian T, Bartocci C, Tsai J,
            Karlseder J and Lazzerini Denchi E.
  TITLE     TZAP: A telomere-associated protein involved in telomere length
            control
  JOURNAL   Science 355 (6325), 638-641 (2017)
   PUBMED   28082411
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CO567542.1, BC098691.1 and BQ200912.1.
            
            On Jun 3, 2008 this sequence version replaced NM_001013216.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-597               CO567542.1         1-597
            598-1606            BC098691.1         528-1536
            1607-1611           BQ200912.1         606-610             c
            1612-2224           BC098691.1         1538-2150
FEATURES             Location/Qualifiers
     source          1..2224
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2224
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /note="zinc finger and BTB domain containing 48"
                     /db_xref="GeneID:362668"
                     /db_xref="RGD:1311581"
     exon            1..102
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            103..774
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             106..2157
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /note="GLI-Kruppel family member HKR3; zinc finger and BTB
                     domain-containing protein 48"
                     /codon_start=1
                     /product="telomere zinc finger-associated protein"
                     /protein_id="NP_001013234.2"
                     /db_xref="GeneID:362668"
                     /db_xref="RGD:1311581"
                     /translation="MDGSFVQHSVRVLQELNKQREKGQYCDATLDVGGLVFKAHWSVL
                     ACCSRFFQRIYGDGSGGSVVLPAGFAEIFGLLLDFFYTGHLALTSGNRDQVLLAAKEL
                     RVPEAVELCQSFQPQTSAGQAQSGPGQVSSQDVKSHLKEPTDLDEEEVFRTLSLASVD
                     QEPRDGEQPQLSTPAQSSPAFLCGKLKQVLKPSPPADKESEDSKEPPRPFEAEGAPLQ
                     GESNEWEVVVQVEDDRDGDGDYASEPETVLTRRKSKVIRKPCAAEPALGAGSLTAEPT
                     EGRKGAAVPVECPTCHKKFLSKYYLKVHNRKHTGEKPFECPKCGKCYFRKENLLEHEA
                     RNCMNRSEQVFTCSVCQETFRRRMELRVHMVSHTGEMPYKCSSCSQQFMQKKDLQSHM
                     IKLHGAPKPHACPTCAKCFLSRTELQLHEAFKHRGEKLFVCEECGHRASSRNGLQMHI
                     KAKHRNERPYVCEFCSHAFTQKANLNMHLRTHTGEKPFQCHLCGKTFRTQASLDKHNR
                     THTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLRVHVRR
                     HKGVRKFECTECGYKFTRQAHLRRHMEIHDRVENYNPRQRKLRNLIIDDEKMVVVALQ
                     PPADLEVGSAEVIVESLTQGGLASQLPSQRLCSEESFASSGVLEPSLIITAAVPEDCD
                     T"
     exon            775..1022
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1023..1134
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1135..1227
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1228..1314
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1315..1469
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1470..1606
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1607..1771
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1772..1860
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
     exon            1861..2199
                     /gene="Zbtb48"
                     /gene_synonym="Hkr3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgtctccg cgctgtgggc cgggcagtag ttagtcttgt gggcggtgga agtggtctag
       61 cccggagcag tgaggccggt gcgagccggg aggaccggca ggattatgga tggttccttc
      121 gtacagcaca gcgtgagggt tctgcaggaa ctcaacaagc agcgtgagaa gggccagtat
      181 tgcgacgcca cgctggacgt ggggggcctg gtgttcaagg cgcactggag tgtcctggcg
      241 tgttgcagcc gtttcttcca gagaatctac ggggatggct cagggggcag tgttgtcctc
      301 cctgcaggtt ttgctgagat ttttggcctc ctgctggact ttttctacac tggccacctc
      361 gccctcacct cagggaacag ggatcaggtg ctcttggcag ccaaagagtt gagggtgcct
      421 gaggctgtgg agctatgtca gagcttccag ccccaaacct cagcgggaca ggcacagagt
      481 ggaccgggcc aagtttcctc ccaggatgtg aaaagccacc tcaaggagcc aacagacttg
      541 gatgaggagg aagttttcag gactctgagc ctggcctctg tggatcagga gcccagagac
      601 ggtgagcagc cccagctcag cacacctgcc cagagcagcc cggccttcct ctgtgggaaa
      661 ctcaagcagg tgttgaagcc ttctccccca gcggacaaag agtctgagga cagcaaagag
      721 cccccaaggc cttttgaagc tgaaggtgcc ccactgcagg gcgagagcaa tgagtgggaa
      781 gtggtggttc aagttgagga cgacagggat ggtgatggcg attatgcatc tgagcctgag
      841 actgtgctga ccaggaggaa gtcaaaagtg attagaaagc cgtgtgcggc agagccagcc
      901 ctgggtgcag gctccctcac agccgagccc accgagggca gaaaaggtgc agcagttccg
      961 gtcgaatgtc ccacatgtca taagaagttc ctcagcaaat actacctaaa agtccacaac
     1021 aggaaacaca ctggggagaa acccttcgag tgtcccaaat gtgggaagtg ttactttcgc
     1081 aaggagaacc tcttggagca tgaagcccgg aattgcatga accgctcaga acaggtcttc
     1141 acatgctccg tatgccagga gaccttccgc cggaggatgg agctgcgggt gcacatggtg
     1201 tctcacacag gggagatgcc ctacaagtgc tcctcctgct cccagcagtt catgcagaag
     1261 aaggacttgc agagccacat gatcaagctg catggagccc ctaaacccca cgcatgcccc
     1321 acttgtgcca agtgcttcct gtctaggacg gagctacagc tgcacgaggc ttttaagcat
     1381 cgtggagaaa agctctttgt gtgtgaagaa tgtgggcacc gggcctcaag ccgcaatggg
     1441 ctgcagatgc acatcaaggc caagcacagg aatgaaaggc cgtatgtctg tgagttctgc
     1501 agccatgcat tcacccagaa ggccaacctc aacatgcacc tgcgcacaca cacaggagag
     1561 aagcccttcc agtgccacct ctgtgggaag accttccgca cccaagccag tctggacaag
     1621 cacaaccgca cccacacggg tgagaggcct tttagctgtg aattctgtga gcagcgcttc
     1681 actgagaagg gcccccttct gaggcatgtg gccagccgtc atcaggaggg cagacctcat
     1741 ttctgccaga tctgtggcaa gaccttcaaa gcagtggaac agttacgggt gcacgtcaga
     1801 cgacacaaag gcgtgagaaa gttcgagtgc accgagtgtg gctacaagtt cactcggcag
     1861 gctcacctgc ggaggcacat ggagatccac gatagagtgg agaactacaa ccctcggcag
     1921 cgcaagctcc ggaacctcat catcgacgat gagaagatgg tggtggtggc tctccagcca
     1981 cctgcagacc tggaggtggg ctccgcagag gtcattgtgg agtccctgac ccagggtggc
     2041 cttgcctccc aactccctag ccagagactg tgttcagagg agagctttgc tagctccggg
     2101 gtcctggagc cgtctctcat catcacggct gctgtccctg aggactgtga cacgtagcct
     2161 gtccagtgtc cccttgacca ataaacatgt gacttaggaa aaaaaaaaaa aaaaaaaaaa
     2221 aaaa
//
