LOCUS       NM_181385               1280 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Rattus norvegicus zygote arrest 1 (Zar1), mRNA.
ACCESSION   NM_181385
VERSION     NM_181385.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1280)
  AUTHORS   Hu,J., Wang,F., Zhu,X., Yuan,Y., Ding,M. and Gao,S.
  TITLE     Mouse ZAR1-like (XM_359149) colocalizes with mRNA processing
            components and its dominant-negative mutant caused two-cell-stage
            embryonic arrest
  JOURNAL   Dev Dyn 239 (2), 407-424 (2010)
   PUBMED   20014101
REFERENCE   2  (bases 1 to 1280)
  AUTHORS   Wu,X., Wang,P., Brown,C.A., Zilinski,C.A. and Matzuk,M.M.
  TITLE     Zygote arrest 1 (Zar1) is an evolutionarily conserved gene
            expressed in vertebrate ovaries
  JOURNAL   Biol Reprod 69 (3), 861-867 (2003)
   PUBMED   12773403
  REMARK    GeneRIF: The carboxyl-termini of these ZAR1 proteins contain an
            important functional domain that is conserved through vertebrate
            evolution and that may be necessary for normal female reproduction
            in the transition from oocyte to embryonic life.
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY283175.1.
            
            On Jun 3, 2003 this sequence version replaced NM_181385.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY283175.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMEA5760396
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1280
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p11"
     gene            1..1280
                     /gene="Zar1"
                     /note="zygote arrest 1"
                     /db_xref="GeneID:353228"
                     /db_xref="RGD:727972"
     exon            1..801
                     /gene="Zar1"
                     /inference="alignment:Splign:2.1.0"
     CDS             28..1113
                     /gene="Zar1"
                     /note="oocyte-specific maternal effect factor"
                     /codon_start=1
                     /product="zygote arrest protein 1"
                     /protein_id="NP_852050.1"
                     /db_xref="GeneID:353228"
                     /db_xref="RGD:727972"
                     /translation="MFPASTPHPCPHPYPPTAAKAGDGWRFGARGCRPEPPSFLPGYR
                     QLMAAEYFDSYQRAQLMALLSRMGPRPVSSRDAAVQVNPRRDASVQCSLGRRTLQPGR
                     RRASPDARPGSCQPRSPARAGRPPRSWRTVALYSPVTFGGLSSSLEVAGDRQTPTKGE
                     GRPAPTGTREPEPGEVAVMKAVPQPQSEEGDVQAEGQDGQEQPPREDPDSVAAMQSEP
                     GSEEPPPAVEMAQDPSDVAASRDRASPQSTEQDKERLRFQFLEQKYGYYHCKDCNIRW
                     ESAYVWCVQGTSKVYFKQFCRVCEKSYNPYRVEDITCQSCKRTRCACPVRLRHVDPKR
                     PHRQDLCGRCKDKRLSCDSTFSFKYII"
     exon            802..894
                     /gene="Zar1"
                     /inference="alignment:Splign:2.1.0"
     exon            895..969
                     /gene="Zar1"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1280
                     /gene="Zar1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgggccggcg aggcgcggga cgcacccatg ttcccggcga gcacgcccca cccatgcccg
       61 catccttacc cgcccacggc agccaaagcc ggggatggct ggaggtttgg agccaggggc
      121 tgcaggcccg agcccccctc cttcctcccc ggctacagac agctcatggc cgcggagtac
      181 tttgacagct atcagcgagc gcagctcatg gccttgctgt cgcgaatggg tccccggccg
      241 gtcagcagcc gcgacgctgc ggtgcaggtg aacccgcgcc gcgatgcctc ggtgcagtgt
      301 tcgctcgggc gccgcacact gcagcctgga cggcgccgag ccagccccga cgcccggcct
      361 ggttcctgcc aaccccgcag ccccgccagg gccgggagac ccccgcgatc ctggcgcacc
      421 gtcgccctgt actcgcccgt gaccttcggt ggcctctcct cctcgctgga ggttgcgggg
      481 gacaggcaga cgcccacgaa gggagagggg agaccggcac ccacggggac ccgggaaccc
      541 gagccgggag aggtggcagt gatgaaagca gtcccccagc cgcagagcga ggagggcgac
      601 gtccaggctg aagggcagga tgggcaggag cagccaccgc gggaggaccc ggacagtgtg
      661 gcggcgatgc agtctgagcc cgggagtgag gagccacctc ctgctgtcga gatggctcag
      721 gaccccagtg acgtggctgc ctctagagac cgggcctccc cacagagcac tgagcaggac
      781 aaggagcgcc tgcgtttcca gttcttagag cagaagtacg gctactatca ctgcaaagac
      841 tgcaacatcc ggtgggagag cgcctatgtg tggtgtgtgc agggcaccag caaggtgtac
      901 ttcaaacagt tctgccgcgt gtgtgagaag tcctacaacc cataccgagt ggaggatatc
      961 acctgccaaa gttgtaaaag gactagatgt gcctgcccgg tcagacttcg ccacgtggac
     1021 cctaaacgcc cccatcgtca agacttgtgt gggagatgca aggacaaacg cctgtcctgt
     1081 gacagcacct tcagcttcaa atatatcatt tagagagagt taaaaatggt tctgctaaat
     1141 ggatcggaca agtgagcctt ctcccacgcc cctctcccct ctccacctct cccttctcaa
     1201 aatacttcat gaaaggcagt gtactttaat ataaagcctg cgaataaaag gggttgcaaa
     1261 cagtttgggg ctttatccaa
//
