LOCUS       NM_001011935            4371 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus exportin 6 (Xpo6), mRNA.
ACCESSION   NM_001011935 XM_238141
VERSION     NM_001011935.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4371)
  AUTHORS   Xing B, Ma J, Jiang Z, Feng Z, Ling S, Szigety K, Su W, Zhang L,
            Jia R, Sun Y, Zhang L, Kong X, Ma X and Hua X.
  TITLE     GLP-1 signaling suppresses menin's transcriptional block by
            phosphorylation in beta cells
  JOURNAL   J Cell Biol 218 (3), 855-870 (2019)
   PUBMED   30792230
REFERENCE   2  (bases 1 to 4371)
  AUTHORS   Fu B, Wang L, Li S and Dorf ME.
  TITLE     ZMPSTE24 defends against influenza and other pathogenic viruses
  JOURNAL   J Exp Med 214 (4), 919-929 (2017)
   PUBMED   28246125
REFERENCE   3  (bases 1 to 4371)
  AUTHORS   Dopie J, Skarp KP, Rajakyla EK, Tanhuanpaa K and Vartiainen MK.
  TITLE     Active maintenance of nuclear actin by importin 9 supports
            transcription
  JOURNAL   Proc Natl Acad Sci U S A 109 (9), E544-E552 (2012)
   PUBMED   22323606
REFERENCE   4  (bases 1 to 4371)
  AUTHORS   Stuven T, Hartmann E and Gorlich D.
  TITLE     Exportin 6: a novel nuclear export receptor that is specific for
            profilin.actin complexes
  JOURNAL   EMBO J 22 (21), 5928-5940 (2003)
   PUBMED   14592989
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC083625.1, CA512173.1, CA511395.1, EV776104.1, CV102769.1,
            DV719797.1 and CA504675.1.
            
            On Aug 28, 2008 this sequence version replaced NM_001011935.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760383,
                              SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1538              BC083625.1         1-1538
            1539-2023           CA512173.1         190-674
            2024-2493           CA511395.1         206-675
            2494-3273           EV776104.1         4-783
            3274-3782           CV102769.1         223-731
            3783-4340           DV719797.1         17-574
            4341-4371           CA504675.1         1-31                c
FEATURES             Location/Qualifiers
     source          1..4371
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q36"
     gene            1..4371
                     /gene="Xpo6"
                     /note="exportin 6"
                     /db_xref="GeneID:293476"
                     /db_xref="RGD:1311491"
     exon            1..444
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     CDS             442..3819
                     /gene="Xpo6"
                     /codon_start=1
                     /product="exportin-6"
                     /protein_id="NP_001011935.2"
                     /db_xref="GeneID:293476"
                     /db_xref="RGD:1311491"
                     /translation="MASEDASLRALESLMTEFFHDCTTNERKREIEELLNNFAQQVGA
                     WRFCLYFLSSTRNDYVMMYSLTVFENLINKMWLGVPSQDKMEIRSCLPKLLLAHHKTL
                     PYFIRNKLCKVIVDIGRQDWPMFYHDFFTNILQLIQSPVTTPLGLIMLKTTSEELACP
                     REDLSVARKEELRKLLLDQVQTVLGLLTGILETVWDKHSVTAATPPPSPTSGESGDLL
                     SNLLQSPSSAKLLHQPIPILDVESEYVCSLALECLAHLFSWIPLSASITPSLLTTIFH
                     FARFGCDTRARKMASVNGSSQNCVLGQERGRLGVLAMSCINELMSKNCVPMEFEEYLL
                     RMFQQTFYLLQKITKDNNAHTVKSRLEELDESYVEKFTDFLRLFVSVHLRRIESYSQF
                     PVLEFLTLLFKYTFHQPTHEGYFSCLDIWTLFLDYLTSKIKSRLGDKEAVLNRYEDAL
                     VLLLTEVLNRIQFRYNQAQLEELDDETLDDDQQTEWQRYLRQSLEVVAKVMELLPTHA
                     FSTLFPVLQDNLEVYLGLQQFVVTSGSGHRLNITAENDCRRLHCSLRDLSSLLQAVGR
                     LAEYFTGDVFAARFSDALTVVERLVKVTLYGSQIKLYNIETAVPSVLKPDLIDVHAQS
                     LAALQAYSHWLAQYCSEAHRQNTQQFVTLISTTMDAITPLISTKVQDKLLLSACHLLV
                     SLATTVRPVFLISIPAMQKVFNSIIDASAQRLTDKAQVLVCRALSNTLLLPWPNLPES
                     EQQWPLRSINHASLISALSRDYHSLKPSAAAPQRKMPLDDTKVIIHQTLSVFEDIVEN
                     ISGESTKSRQICYQSLQESVQVSLALFPAFIHQSDVTDEMLSFFLTLFRGLRVQMGVP
                     FTEQIIQTFLNMFTREQLAESILHEGSTGCRVVEKFLKILQVVVQEPGQVFKPFLPSI
                     IALCMEQVYPIIAERPSPDVKAELFELLFRTLHHNWRYFFKSTVLASVQRGIAEEQME
                     NEPQFSAIMQAFGQSFLQPDIHLFKQNLFYLETLNTKQKLYHKKIFRTTMLFQFVNVL
                     LQVLVHKSHDLLQEEIGIAIYNMASVDFDGFFAAFLPEFLTSCDGVDANQKNVLGRNF
                     KMDRDLPSFTQNVHRLVNDLRYYRLCNDSLPPGTVKL"
     exon            445..535
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            536..648
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            649..846
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            847..1006
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1007..1084
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1538
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1539..1665
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1666..1775
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1776..1884
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1885..1977
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            1978..2047
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2048..2207
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2208..2300
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2301..2445
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2446..2592
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2593..2782
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2783..2938
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            2939..3053
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            3054..3225
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            3226..3387
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            3388..3486
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            3487..3717
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
     exon            3718..4358
                     /gene="Xpo6"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cgaggacagc gcgggcccgt gggcctctct tctgagccgg ccgcgccgcc caggcccagg
       61 cagcctctgc cccttcagtc ttagctgggg cccgtcgccg cctcgggccg cggaggccag
      121 ggagtccctg cctgggcccg tagcctccct ctcgggggtc gggcccaggc ggggggcccc
      181 gtgtagccgc ctctgaaccc aattttctgc ttttgagttt gtctggggtg ggccgaggtc
      241 tggatgaatc gcttcggggg gtccctgaag gggcccgtgt gctcctttta aaggtgtcgg
      301 ctggacccgg gtggggaacg ggttgtcttt gcatgggcgg gggactcccc gagcctgccg
      361 ggaccatgac ctgaactgtg cgagcgggac gcgacggatc ccaagagcca gctcacctga
      421 gccacccact tcccggccag catggcatct gaagacgcct cgctcagggc attggaaagc
      481 ctgatgacag aatttttcca tgactgcaca accaatgaaa ggaagcgtga gatagaggaa
      541 cttcttaata actttgccca gcaagtagga gcttggagat tctgcttata ttttctgtcc
      601 agcacaagga atgactacgt aatgatgtac agcttaacgg tttttgagaa tctaatcaat
      661 aaaatgtggc ttggggtccc atctcaggat aagatggaaa tccgcagctg cttacccaaa
      721 cttctcttgg ctcaccataa aaccttacct tattttattc ggaacaaact ctgcaaagtt
      781 attgttgata ttggacgcca agattggccc atgttctacc atgacttttt cactaatatt
      841 ttacagttga tccagtcccc tgtgacaacc ccccttgggc tgatcatgtt gaagacaact
      901 tcggaagagc tagcttgtcc ccgtgaggat ctcagtgtgg ctcggaagga ggagttgcgg
      961 aagctgctgc tggaccaggt gcagacagtg cttgggctct tgacaggtat cttggaaact
     1021 gtctgggaca agcacagtgt tactgctgcc accccaccac catccccgac atcaggagaa
     1081 agtggtgatt tactgagtaa cctgttgcag agtcctagtt cagccaaact gctgcaccag
     1141 cccatcccca tcctggatgt ggagagtgag tatgtctgtt ccctggcctt ggagtgtctg
     1201 gcccacctct tcagttggat tcctctgtct gccagcatca ccccatccct cctcaccact
     1261 atcttccact ttgctcgatt tggctgtgat acccgggcca gaaagatggc gtcagtgaat
     1321 ggcagcagcc agaactgtgt tttgggtcag gagcgtggcc gacttggggt cttggccatg
     1381 tcctgcatca atgaactcat gtccaagaac tgtgtgccta tggaatttga ggagtactta
     1441 ttgcgaatgt tccaacaaac cttctacctc ctgcaaaaaa tcaccaagga taacaatgcc
     1501 cacacggtga agagcaggct agaggaactc gatgagagct acgttgagaa gtttactgac
     1561 tttctgcggc tctttgtgag cgttcaccta agaagaatcg agtcctattc ccagttccct
     1621 gtgctggagt tcctgaccct tctgttcaag tatacgtttc accagcccac tcatgaaggt
     1681 tacttctctt gtttggatat ctggacactg tttttggact atctgacaag taaaattaaa
     1741 agtcgtctgg gagacaagga agcagttctc aacaggtacg aagatgccct ggtccttttg
     1801 cttacagagg tgttgaatcg aatccagttc agatacaacc aggcccaact agaggagctg
     1861 gatgatgaga ctctggatga cgatcagcag acagagtggc agcggtactt acgccagagc
     1921 ttggaggtag tggccaaagt gatggagctc cttcccacac atgccttctc aactctgttc
     1981 ccagttcttc aggacaattt agaagtttat ttgggattac agcaattcgt agttacttcg
     2041 gggtcaggac acaggctgaa catcacagcg gagaatgact gccggcgttt gcactgctcc
     2101 ctgcgagact tgagttccct gctgcaggct gtgggccgat tagctgaata cttcactggg
     2161 gatgtgtttg ctgcaaggtt cagtgatgct ctcacagttg tggagaggtt ggtcaaagtt
     2221 actctttatg gatctcagat aaaactgtac aacattgaaa cagccgtgcc atcagtgttg
     2281 aaacctgacc tcattgatgt gcacgctcag tcacttgcag ctctccaggc ctactcccac
     2341 tggttggcac agtattgcag cgaagcccat cgacagaaca cacagcagtt tgtgacactc
     2401 atctctacca caatggatgc catcacacct ctcatcagca ccaaggtcca agacaagttg
     2461 ctgctgtctg cgtgccacct actggtctca ctagccacca cggtgcggcc tgtctttctg
     2521 atcagtatcc ctgcaatgca gaaggtgttc aacagcatca tcgatgcctc tgcccagcgc
     2581 ctaacagaca aggcacaggt gttggtttgc cgtgcacttt ctaacacctt gcttcttcca
     2641 tggccaaatc ttcctgagag tgagcagcag tggcccctgc gctccatcaa ccatgccagc
     2701 ctcatctctg cactctcccg ggactaccac agcctgaagc ccagtgctgc tgccccccag
     2761 agaaagatgc cactggatga caccaaagtg attattcacc agacacttag tgtctttgaa
     2821 gatatcgtgg agaatatttc tggggaatcc accaagtcgc ggcagatctg ctaccagtca
     2881 ctgcaggaat ctgttcaggt ctccctggcc ctctttccag cttttatcca tcagtcagat
     2941 gtgactgatg agatgctgag cttcttcctc accttgttcc gaggccttag agtgcagatg
     3001 ggcgtgcctt tcaccgagca gatcatacag actttcctca acatgtttac cagagagcag
     3061 ttggctgaga gtatcctcca tgaaggcagt actggctgcc gggtggtgga gaagttcttg
     3121 aagatcctac aagtggttgt tcaggagcct ggccaggtgt tcaagccttt cctccccagc
     3181 atcattgcgc tgtgcatgga gcaagtgtac cccatcattg ctgagcgccc gtcccctgat
     3241 gtcaaggctg agctgtttga gctccttttt cgaacgctcc atcacaactg gcggtacttc
     3301 tttaagtcca ctgtcctagc tagcgtgcag aggggtattg ccgaggagca gatggagaat
     3361 gaaccccagt tcagtgccat catgcaggct tttggacagt cctttcttca acctgacatc
     3421 cacctgttca aacaaaatct cttctacttg gagactctga acacgaagca gaaactatac
     3481 cacaaaaaga tcttccggac cactatgctg ttccagtttg tgaacgtgct gctccaggtc
     3541 ctggttcata agtctcatga ccttctgcag gaggagatcg gcattgccat ttacaacatg
     3601 gcttctgtcg actttgatgg cttctttgca gcctttcttc cagagttcct gactagctgt
     3661 gatggtgtgg atgccaatca gaaaaatgtt ctggggcgga atttcaagat ggatcgggac
     3721 ctaccctcgt ttacccagaa tgtgcacaga ctggtaaatg atctacgtta ctaccgactc
     3781 tgcaatgaca gcctgccccc tggcaccgtg aagctctagg agtgcctgct gccaccgcca
     3841 cctacaccac ctgcacctgt gccacggaag tctgtgacaa gccttggcca ctctctggat
     3901 gggcatgcct tgagcaagtt gcctgcctct gccctctcct gctgccacca gcacagcagg
     3961 tgttggagtc catttggcac tggtagagtt tccatgcatt tggagcaggc agagggccct
     4021 gtggctggat gccagggaag taccagagac cccacagagt ggttcatgca gatcatgtgt
     4081 gtcagtcctg agtcagaatc gccaaggacc acttacgaca gtgccacctt ctcaccattc
     4141 cacctctcca cctctcctgg cccagccagc ccaggagaaa ttccacattg gaactgtttc
     4201 tgtcgagcct cctgcccctc caattgcctt gaagtctctg ctctttgtca gagattctcg
     4261 aagactctcg ggtttttgtt ccttgttttc tcatcattcc attgtgatac taagaagctt
     4321 aatgaataaa taaaatgctt aagttgttgt tatataaaaa aaaaaaaaaa a
//
