LOCUS       NP_001101344             933 aa            linear   ROD 26-FEB-2024
DEFINITION  DNA repair protein complementing XP-C cells [Rattus norvegicus].
ACCESSION   NP_001101344 XP_001073450 XP_232194
VERSION     NP_001101344.1
DBSOURCE    REFSEQ: accession NM_001107874.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 933)
  AUTHORS   Semer M, Bidon B, Larnicol A, Caliskan G, Catez P, Egly JM, Coin F
            and Le May N.
  TITLE     DNA repair complex licenses acetylation of H2A.Z.1 by KAT2A during
            transcription
  JOURNAL   Nat Chem Biol 15 (10), 992-1000 (2019)
   PUBMED   31527837
REFERENCE   2  (residues 1 to 933)
  AUTHORS   Bidon B, Iltis I, Semer M, Nagy Z, Larnicol A, Cribier A, Benkirane
            M, Coin F, Egly JM and Le May N.
  TITLE     XPC is an RNA polymerase II cofactor recruiting ATAC to promoters
            by interacting with E2F1
  JOURNAL   Nat Commun 9 (1), 2610 (2018)
   PUBMED   29973595
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 933)
  AUTHORS   Cattoglio C, Zhang ET, Grubisic I, Chiba K, Fong YW and Tjian R.
  TITLE     Functional and mechanistic studies of XPC DNA-repair complex as
            transcriptional coactivator in embryonic stem cells
  JOURNAL   Proc Natl Acad Sci U S A 112 (18), E2317-E2326 (2015)
   PUBMED   25901318
REFERENCE   4  (residues 1 to 933)
  AUTHORS   Guthrie OW and Xu H.
  TITLE     Noise exposure potentiates the subcellular distribution of
            nucleotide excision repair proteins within spiral ganglion neurons
  JOURNAL   Hear Res 294 (1-2), 21-30 (2012)
   PUBMED   23022597
REFERENCE   5  (residues 1 to 933)
  AUTHORS   Kamileri I, Karakasilioti I and Garinis GA.
  TITLE     Nucleotide excision repair: new tricks with old bricks
  JOURNAL   Trends Genet 28 (11), 566-573 (2012)
   PUBMED   22824526
  REMARK    Review article
REFERENCE   6  (residues 1 to 933)
  AUTHORS   Sugasawa K, Ng JM, Masutani C, Iwai S, van der Spek PJ, Eker AP,
            Hanaoka F, Bootsma D and Hoeijmakers JH.
  TITLE     Xeroderma pigmentosum group C protein complex is the initiator of
            global genome nucleotide excision repair
  JOURNAL   Mol Cell 2 (2), 223-232 (1998)
   PUBMED   9734359
REFERENCE   7  (residues 1 to 933)
  AUTHORS   Cheo DL, Ruven HJ, Meira LB, Hammer RE, Burns DK, Tappe NJ, van
            Zeeland AA, Mullenders LH and Friedberg EC.
  TITLE     Characterization of defective nucleotide excision repair in XPC
            mutant mice
  JOURNAL   Mutat Res 374 (1), 1-9 (1997)
   PUBMED   9067411
REFERENCE   8  (residues 1 to 933)
  AUTHORS   Shivji MK, Eker AP and Wood RD.
  TITLE     DNA repair defect in xeroderma pigmentosum group C and
            complementing factor from HeLa cells
  JOURNAL   J Biol Chem 269 (36), 22749-22757 (1994)
   PUBMED   8077226
REFERENCE   9  (residues 1 to 933)
  AUTHORS   Masutani C, Sugasawa K, Yanagisawa J, Sonoyama T, Ui M, Enomoto T,
            Takio K, Tanaka K, van der Spek PJ, Bootsma D et al.
  TITLE     Purification and cloning of a nucleotide excision repair complex
            involving the xeroderma pigmentosum group C protein and a human
            homologue of yeast RAD23
  JOURNAL   EMBO J 13 (8), 1831-1843 (1994)
   PUBMED   8168482
REFERENCE   10 (residues 1 to 933)
  AUTHORS   Li L, Bales ES, Peterson CA and Legerski RJ.
  TITLE     Characterization of molecular defects in xeroderma pigmentosum
            group C
  JOURNAL   Nat Genet 5 (4), 413-417 (1993)
   PUBMED   8298653
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473957.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XP_001073450.1, XP_232194.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..933
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q34"
     Protein         1..933
                     /product="DNA repair protein complementing XP-C cells"
                     /note="xeroderma pigmentosum, complementation group C"
                     /calculated_mol_wt=104730
     Region          144..860
                     /region_name="rad4"
                     /note="DNA repair protein rad4; TIGR00605"
                     /db_xref="CDD:273170"
     CDS             1..933
                     /gene="Xpc"
                     /coded_by="NM_001107874.1:60..2861"
                     /db_xref="GeneID:312560"
                     /db_xref="RGD:1305760"
ORIGIN      
        1 markrtaggk rrkrgqeaed nkatrpeesd addfedekqk pprkcflpkv sqgkrkrdcs
       61 dpgdptngaa kkkvakattk sknlkavkee alsddgddfr dslsncrkak khpkrevvdq
      121 gtdeddsedd weeveeltep vldmgensat srsdlpvkav eieietpeqa karersekik
      181 mefetylrrm mkrfnkevqe nmhkvhllcl lasgfyrnsi cqqpdllaig lsiipirftk
      241 vplqdrdvyy lsnlvkwfig tftvnadlsa seqdslqttl erriaiysar dneelvhifl
      301 lilralqllt rlvlslqpip lksavakgkk ssketslegp gdssepssni peshnkpkts
      361 krikqeetls egsgkanarg krgtatagsr qqrkpscseg eeakqeiqsh pqaqkrrvaa
      421 kvsykeeses dgagsgsdfe lssgegqhss dedckpgprk qkrasapqrs kagsksaskt
      481 qsgsqwepps fsvasssssa ckrgkkiscg geetddrkaa gvdqwlevfc epqakwvcvd
      541 cvhgvvgqpv acykyatkpm tyvvgidsdg wvrdvtqryd pawmtatrkc rvdaewwaet
      601 lrpyrsplte rekkedqefq akhldqplpt sistyknhpl yalkrhllkf qaiypesaav
      661 lgycrgeavy srdcvhtlhs rdtwlkqarv vrlgevpykm vkgfsnrark arlsepqlhd
      721 hndlglfghw qteeyqppva vdgkvprnef gnvylflpsm mpigcvqmnl pnlhrvarkl
      781 gidcvqaitg fdfhggychp vtdgyvvcee frdvllaawe neqaliekke kekkekralg
      841 nwkllvrgll irerlklryg akseaaapha naggglssde eegtssqaea arvlaaswpq
      901 nretkeeqkp dytkmtrrrr aaeashlfpf ekl
//
