LOCUS       NM_001012099            2671 bp    mRNA    linear   ROD 20-MAR-2023
DEFINITION  Rattus norvegicus XK related 8 (Xkr8), mRNA.
ACCESSION   NM_001012099 XM_232742
VERSION     NM_001012099.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2671)
  AUTHORS   Kawano M and Nagata S.
  TITLE     Lupus-like autoimmune disease caused by a lack of Xkr8, a
            caspase-dependent phospholipid scramblase
  JOURNAL   Proc Natl Acad Sci U S A 115 (9), 2132-2137 (2018)
   PUBMED   29440417
REFERENCE   2  (bases 1 to 2671)
  AUTHORS   Suzuki J, Denning DP, Imanishi E, Horvitz HR and Nagata S.
  TITLE     Xk-related protein 8 and CED-8 promote phosphatidylserine exposure
            in apoptotic cells
  JOURNAL   Science 341 (6144), 403-406 (2013)
   PUBMED   23845944
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY534262.1.
            
            On Feb 11, 2005 this sequence version replaced XM_232742.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY534262.1, EV773377.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132267, SAMD00132268
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2671
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2671
                     /gene="Xkr8"
                     /gene_synonym="RGD1305649; XRG8"
                     /note="XK related 8"
                     /db_xref="GeneID:313033"
                     /db_xref="RGD:1305649"
     exon            1..1178
                     /gene="Xkr8"
                     /gene_synonym="RGD1305649; XRG8"
                     /inference="alignment:Splign:2.1.0"
     CDS             886..2085
                     /gene="Xkr8"
                     /gene_synonym="RGD1305649; XRG8"
                     /note="X Kell blood group precursor related family member
                     8 homolog; X-linked Kx blood group related 8; XK, Kell
                     blood group complex subunit-related family, member 8"
                     /codon_start=1
                     /product="XK-related protein 8"
                     /protein_id="NP_001012099.1"
                     /db_xref="GeneID:313033"
                     /db_xref="RGD:1305649"
                     /translation="MPLSVHPQVALDVVIGLVSTLSFLLDLVADLWAVVQYVLVGRYL
                     WAALVVVLLGQASVLLQLFSWLWLTADPTELHQLQPSRRFLALLHLLQLGYLYRCLHG
                     MRQGLSMCCQEVPSECDLAYADFLSLDISMLRLFESFLEATPQLTLVLAIVLQSGNAE
                     YYQWFGISSSFLGISWALLDYHRSLRTCLPSKPRLGWCSSAVYFLWNLLLLGPRICAI
                     ATFSVVFPYCLALHFLSLWLVLLYWVWLQDTKFMPNSNGEWLYRVTVALILYFSWFNV
                     SGGRTRGRATIHLGFILSDSVLLVTTSWVTDSTWLPGGVLLWAALGGACFSLGLVLRM
                     IYYLRLHPSCSWEPDFVDGTLRLLPPERPPKLIYNRRATRLAQNFFAKLKTQAALPQA
                     VQLNGVL"
     exon            1179..1375
                     /gene="Xkr8"
                     /gene_synonym="RGD1305649; XRG8"
                     /inference="alignment:Splign:2.1.0"
     exon            1376..2654
                     /gene="Xkr8"
                     /gene_synonym="RGD1305649; XRG8"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtgaggacg tctgccgaag ggagcatgtg tgcgccatac agcacgtgga gttcgacact
       61 tacgccacct gcttgcatgg tcttggtgcc aacctggtac ctggtttcct gctcatactg
      121 actctgctga cgagcctaca cgtattggag gtgctatgac tgtaggcact gccagcctac
      181 cctcttactt ggttcgtctt tctccctggt aaaactgggc aacattaccc aatggagaga
      241 gagggagatg aattttgcca tcagtctgtg gagagtaagg tgggatggga catttggatt
      301 caccagagag ggcgctaaga agcacatttc ttctgagttt tatgttttat ccacagagct
      361 tgtttgcggt acatgtcttg gtgcattatt ccctttaata caaacatcaa actatcatgc
      421 acttgatcgc cacagtaaag tgaacccgca ggaagatggg ccctggagag tctgtgcttt
      481 tgagtccctg ctcaaggtct aaaactggga acccacgtgg tctgcaaaat cccttggtac
      541 ttttaaataa aagacttttc tgatttggtt tcgcaacagt gcaaccgtga gggatcacag
      601 ctgcgaccca gacactagtc ttgtggccac tcttgttaac tagagcctca aaaggcagaa
      661 tccaaaccag tagaggcagg gctcaagaca gggagggctg ggggcggggt ctgggcggtg
      721 ggaccgccta gggggcggag tcgtggactc gctcctcccc ggacggggcg agatggggaa
      781 gttccgccca gcagcccggc ctctgggagg actgccccac ccccttcctg ccggactagc
      841 cgggctggag ggcagatccg cggttgtgag gttgcctgga gggccatgcc tctgtccgtg
      901 cacccccaag tggccttaga cgtggtcata ggtctggtga gtaccttgtc tttcctgttg
      961 gacctggtcg ccgacctgtg ggccgtcgtc cagtacgtgc tcgttggccg ttacctgtgg
     1021 gccgcgctgg tagtggtgct gctgggccaa gcctcggtgc tgctgcagct cttcagctgg
     1081 ctctggctga cagctgaccc caccgagctg caccagttgc agccctcgcg tcgtttcctg
     1141 gctctgctgc acctgctgca gctcggctac ctgtataggt gcctgcacgg aatgcggcag
     1201 ggactgtcca tgtgctgcca ggaggtaccg tctgaatgtg acctggccta tgctgacttc
     1261 ctctccctgg acatcagcat gctgcggctt tttgagagct tcttggaggc gaccccacag
     1321 ctcacgctgg tgctggccat cgtgttgcag agtggaaatg ccgaatacta ccagtggttt
     1381 ggcatcagct catcctttct gggcatctcg tgggcattgc tggactacca tcggtccttg
     1441 cgcacctgcc tcccctccaa gccgcgcctg ggctggtgct cctctgcggt ctacttcctg
     1501 tggaacctgc tgctgttggg gccccggatc tgtgccatcg ccacgttctc ggtcgtcttt
     1561 ccctactgct tggccctgca tttcctcagc ctgtggctgg tgctgttgta ctgggtctgg
     1621 cttcaagaca cgaagtttat gccaaactct aatggcgagt ggctataccg ggtgacggtg
     1681 gcgctcatcc tttatttctc ctggttcaat gtgtctgggg gtcgcactcg aggccgggcc
     1741 actatccacc tgggcttcat cctcagtgac agtgttctgc ttgtcaccac ctcctgggtg
     1801 acagatagta cctggttgcc cggtggggtc ttattgtggg cggctttagg cggcgcctgc
     1861 ttctccctgg gactggtttt gcgtatgatc tactacctcc ggctgcaccc tagctgcagc
     1921 tgggaacccg actttgtgga tgggacccta agactcctcc ctcccgagcg tcctccaaag
     1981 ctgatttata acaggcgtgc cactcggtta gcacagaact tctttgccaa gctcaaaacc
     2041 caggccgccc tgccacaggc ggtacagctg aacggagtcc tctgaggcag ggtctgattc
     2101 agccagtgag gaagatgagg agagtggggc cttgcaaggg acaagggggc caatcatgtg
     2161 caagccagtt tttttcctct ccaaccgata gagcttccat tgccaaatct tcagttgtta
     2221 ccactttcac ctctcacgtg attggtggcg tcctggttcc tggttcccta gcctgctcta
     2281 gatgacagac tctgggggat gttctcgaga actcttccct aacctatccc atccattcac
     2341 ttcccccaac aaatgcactg atgttctggg agcatcatcc tgacttctga actggctgcc
     2401 accctagctt ctttccctgc ccacctggac aaatcctccg tagactcttg aagagcggag
     2461 ggaggccaga gatgcccctc cagtgtcctg acgttcaggc tcttaggcca ccttacacca
     2521 agtgccttat ggacctgtgg cctaggccat gtgatgccca ccaagtattt ttcattctcc
     2581 tacctcagtc tgtgtgaaag aagaacatgt gtgcatgtgt ttaacagtat taaaacctca
     2641 cgagagtctc caaaaaaaaa aaaaaaaaaa a
//
