LOCUS       XM_039097629            2360 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus WW domain containing E3 ubiquitin
            protein ligase 2 (Wwp2), transcript variant X1, mRNA.
ACCESSION   XM_039097629
VERSION     XM_039097629.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051354.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2360
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="19"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2360
                     /gene="Wwp2"
                     /note="WW domain containing E3 ubiquitin protein ligase 2;
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 34 ESTs, 1 long SRA read, 10 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 14 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:291999"
                     /db_xref="RGD:1310091"
     CDS             16..2145
                     /gene="Wwp2"
                     /codon_start=1
                     /product="NEDD4-like E3 ubiquitin-protein ligase WWP2
                     isoform X1"
                     /protein_id="XP_038953557.1"
                     /db_xref="GeneID:291999"
                     /db_xref="RGD:1310091"
                     /translation="MVPNPYQAGCSLCCRVQSQPSGGYSQQQALWTHRHSGGSARTAT
                     ATGEQSPGARNRHRQPVKNPSSSGLANGTVSEEPTTASDPEELSVVGVTSPPAAASSV
                     SPNPNTTSLPAPSTPAEGEEPSTSGTQQLPAAAQAPDALPAGWEQRQLPNGRVYYVDH
                     NTKTTTWERPLPPGWEKRTDPRGRFYYVDHNTRTTTWQRPTAEYVRNYEQWQSQRNQL
                     QGAMQHFSQRFLYQSSSASTDHDPLGPLPPGWEKRQDNGRVYYVNHNTRTTQWEDPRT
                     QGMIQEPALPPGWEMKYTSEGVRYFVDHNTRTTTFKDPRPGFESGTKQGSPGAYERSF
                     RWKYHQFRFLCHSNALPSHVKISVSRQTLFEDSFQQIMNMKPYDLRRRLYIIMRGEEG
                     LDYGGIAREWFFLLSHEVLNPMYCLFEYAGKNNYCLQINPASSINPDHLTYFRFIGRF
                     IAMALYHGKFIDTGFTLPFYKRMLNKRPTLRDLESIDPEFYNSIIWIKENNLDECGLE
                     LFFIQDMEILGKVTTHELKEGGENIRVTEENKEEYIMLLTDWRFTRGVEEQTKAFLDG
                     FNEVAPLEWLRYFDEKELELMLCGMQEIDMSDWQKNAIYRHYTKSSKQIQWFWQVVKE
                     MDNEKRIRLLQFVTGTCRLPVGGFAELIGSNGPQKFCIDRVGKETWLPRSHTCFNRLD
                     LPPYKSYEQLKEKLLYAIEETEGFGQE"
ORIGIN      
        1 caggtatgcg gtgggatggt tccgaacccc taccaagccg gctgttcttt atgctgcagg
       61 gttcagtccc agccttctgg aggatattct cagcagcagg cgctctggac gcacagacat
      121 tcaggtggct cagccaggac agccacagca actggcgaac aaagtcctgg tgctaggaac
      181 cgccaccgcc aacctgtgaa gaaccccagc agcagtggct tagccaatgg cacagtgagt
      241 gaggaaccta cgacagccag cgatcctgaa gaactgtcgg ttgttggtgt gacatcgccg
      301 cctgctgcag cctccagtgt gtccccaaat cccaacacga catctctccc tgcaccgtcc
      361 acaccagctg agggagaaga gcccagcact tccgggacac agcagctccc tgctgctgcc
      421 caggcccctg atgctcttcc tgctggatgg gaacagagac agctgcccaa tgggcgtgtc
      481 tattatgttg atcacaatac caagaccacc acctgggagc ggcctcttcc tccaggatgg
      541 gaaaagcgca cagacccccg agggaggttt tactacgtgg accacaacac ccggacaacc
      601 acctggcagc gcccgactgc tgagtacgtg cggaactatg agcagtggca gtcacagcgg
      661 aatcagctgc agggggccat gcagcacttc agccaaagat tcctctacca gtcttcgagt
      721 gcttcgactg accatgatcc cttgggcccc ctcccgcctg gctgggagaa gaggcaggac
      781 aatggccggg tgtattacgt gaaccacaac acacgcacta cccaatggga ggacccgcgg
      841 acgcagggaa tgatacagga gccagccctg cccccagggt gggagatgaa gtacaccagc
      901 gagggcgtgc ggtactttgt ggatcacaac acccgcacta ccacctttaa ggatcctcgc
      961 ccagggttcg agtcagggac aaagcagggc tcgcctggtg cctatgagcg aagtttccgg
     1021 tggaagtatc accagttccg cttcctctgc cactcaaatg ccctacccag ccacgtgaag
     1081 atcagcgttt ccaggcagac tctctttgag gattctttcc aacagattat gaacatgaaa
     1141 ccttacgacc tgcgccgccg gctctacatc atcatgcgtg gtgaggaggg cctggactac
     1201 ggcggcatcg ccagagagtg gtttttcctc ctgtcccatg aggtgctcaa ccctatgtac
     1261 tgtttgtttg aatatgctgg gaagaacaat tactgcctgc agatcaaccc ggcctcttcc
     1321 atcaaccctg accacctcac ctacttccgc tttatcggca gattcatcgc catggctctg
     1381 taccatggaa agttcatcga cacaggcttc accctccctt tctacaagcg gatgctcaac
     1441 aagagaccaa ctctcaggga cctggagtct attgaccctg agttttacaa ctccattatc
     1501 tggatcaaag agaacaacct ggatgagtgt ggcctggagc tgttcttcat ccaggacatg
     1561 gagatcctgg gcaaggtgac aacccatgaa ctgaaggaag gcggagagaa catccgagtt
     1621 actgaggaga acaaggagga gtatatcatg ctgctgactg actggcgatt cacccgaggt
     1681 gtggaagagc agaccaaagc cttcctggat ggcttcaatg aggtggcccc tctggagtgg
     1741 ttgagatatt ttgatgaaaa agagctggag ctcatgctgt gtggcatgca ggagattgac
     1801 atgagtgact ggcagaagaa cgccatctat cggcactaca ccaagagcag caagcagatc
     1861 cagtggttct ggcaggttgt gaaggagatg gacaatgaga agaggatccg gctactgcag
     1921 tttgtcacgg gaacctgccg cctgcctgtt gggggctttg ctgagctcat tgggagcaat
     1981 ggaccccaga agttctgcat tgacagagtt ggcaaggaaa cctggctgcc taggagccat
     2041 acatgcttca accgcctgga tctgcctccc tacaagagct acgagcagct gaaagagaag
     2101 ctgctgtatg ccatcgagga gactgagggt tttggacagg agtagctgag gctgcccctc
     2161 tcacaccctc cagcacatgt agtcctgagt cctgcctgcc tgagaggcca ccggctgcac
     2221 agccctcgag aggccccttt ggatagtggc cctgcacgag actgtgcttt gatcatgttg
     2281 gtgactgaag aggccttggg gaccctttct tctctctgat gatggcagtc tggaataaag
     2341 ccctgtcacc tttgactcca
//
