LOCUS       NM_001400841            1933 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus WT1 interacting protein (Wtip), mRNA.
ACCESSION   NM_001400841 XM_008759260
VERSION     NM_001400841.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1933)
  AUTHORS   Foxler,D.E., Bridge,K.S., James,V., Webb,T.M., Mee,M., Wong,S.C.,
            Feng,Y., Constantin-Teodosiu,D., Petursdottir,T.E., Bjornsson,J.,
            Ingvarsson,S., Ratcliffe,P.J., Longmore,G.D. and Sharp,T.V.
  TITLE     The LIMD1 protein bridges an association between the prolyl
            hydroxylases and VHL to repress HIF-1 activity
  JOURNAL   Nat Cell Biol 14 (2), 201-208 (2012)
   PUBMED   22286099
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1933)
  AUTHORS   Bai,S.W., Herrera-Abreu,M.T., Rohn,J.L., Racine,V., Tajadura,V.,
            Suryavanshi,N., Bechtel,S., Wiemann,S., Baum,B. and Ridley,A.J.
  TITLE     Identification and characterization of a set of conserved and new
            regulators of cytoskeletal organization, cell morphology and
            migration
  JOURNAL   BMC Biol 9, 54 (2011)
   PUBMED   21834987
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1933)
  AUTHORS   James,V., Zhang,Y., Foxler,D.E., de Moor,C.H., Kong,Y.W.,
            Webb,T.M., Self,T.J., Feng,Y., Lagos,D., Chu,C.Y., Rana,T.M.,
            Morley,S.J., Longmore,G.D., Bushell,M. and Sharp,T.V.
  TITLE     LIM-domain proteins, LIMD1, Ajuba, and WTIP are required for
            microRNA-mediated gene silencing
  JOURNAL   Proc Natl Acad Sci U S A 107 (28), 12499-12504 (2010)
   PUBMED   20616046
REFERENCE   4  (bases 1 to 1933)
  AUTHORS   Das Thakur,M., Feng,Y., Jagannathan,R., Seppa,M.J., Skeath,J.B. and
            Longmore,G.D.
  TITLE     Ajuba LIM proteins are negative regulators of the Hippo signaling
            pathway
  JOURNAL   Curr Biol 20 (7), 657-662 (2010)
   PUBMED   20303269
REFERENCE   5  (bases 1 to 1933)
  AUTHORS   Ayyanathan,K., Peng,H., Hou,Z., Fredericks,W.J., Goyal,R.K.,
            Langer,E.M., Longmore,G.D. and Rauscher,F.J. 3rd.
  TITLE     The Ajuba LIM domain protein is a corepressor for SNAG domain
            mediated repression and participates in nucleocytoplasmic Shuttling
  JOURNAL   Cancer Res 67 (19), 9097-9106 (2007)
   PUBMED   17909014
REFERENCE   6  (bases 1 to 1933)
  AUTHORS   Florea,L., Di Francesco,V., Miller,J., Turner,R., Yao,A.,
            Harris,M., Walenz,B., Mobarry,C., Merkulov,G.V., Charlab,R.,
            Dew,I., Deng,Z., Istrail,S., Li,P. and Sutton,G.
  TITLE     Gene and alternative splicing annotation with AIR
  JOURNAL   Genome Res 15 (1), 54-66 (2005)
   PUBMED   15632090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 27, 2022 this sequence version replaced XM_008759260.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC167052.1, SRR21887622.686165.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-772               JAXUCZ010000001.1  95901313-95902084   c
            773-874             JAXUCZ010000001.1  95893519-95893620   c
            875-942             JAXUCZ010000001.1  95876913-95876980   c
            943-1005            JAXUCZ010000001.1  95876711-95876773   c
            1006-1136           JAXUCZ010000001.1  95876391-95876521   c
            1137-1188           JAXUCZ010000001.1  95875345-95875396   c
            1189-1257           JAXUCZ010000001.1  95874626-95874694   c
            1258-1933           JAXUCZ010000001.1  95868399-95869074   c
FEATURES             Location/Qualifiers
     source          1..1933
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q21"
     gene            1..1933
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /note="WT1 interacting protein"
                     /db_xref="GeneID:361552"
                     /db_xref="RGD:1306411"
     exon            1..772
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     CDS             205..1398
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /note="Wilms tumor 1 interacting protein"
                     /codon_start=1
                     /product="Wilms tumor protein 1-interacting protein"
                     /protein_id="NP_001387770.1"
                     /db_xref="GeneID:361552"
                     /db_xref="RGD:1306411"
                     /translation="MQRSRTAADDAALLLAGLGLRESEPTAGSPGRVRRGPRAADETA
                     PVSGRRGKGGGGPEAAPDVPSRPERGPRASLAGSDGGSARSSGISLGYDQRHGPGPGP
                     PSGGSARSSVSSLGSRGSAGACADLLPPGVGPTPARSPEPAQFPFPLPSLPLPPGREG
                     GPSAAERRLEALTRELERALEARTARDYFGICIKCGLGIYGARQACQAMGSLYHTDCF
                     ICDSCGRRLRGKAFYNVGEKVYCQEDFLYSGFQQTADKCSVCGHLIMEMILQALGKSY
                     HPGCFRCSVCNECLDGVPFTVDVENNIYCVRDYHTVFAPKCASCARPILPAQGCETTI
                     RVVSMDRDYHVECYHCEDCGMQLSGEEGRRCYPLEGHLLCRRCHLRRLGQGPLPSPAV
                     HVTEL"
     exon            773..874
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            875..942
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            943..1005
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1136
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1188
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            1189..1257
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1933
                     /gene="Wtip"
                     /gene_synonym="AABR07002945.1; RGD1306411"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgcgcgcat tccttcgccg cgcgtctccg tccctccccg ccacggcccc gcgcgagcgc
       61 gcggcccacg ccgagcgacc gctaccccgc cccgcgctca ggggtcccgg ggcgggctgc
      121 gggcaggcgg acgatgcggc ggcgctgccg gagcggcggc ggcggcggga ggcggaggtg
      181 acgcgccgcg gcgggccgac ggccatgcag cgctcgcgga cagccgcgga cgacgcggct
      241 ctgctcctgg ccgggctggg cctgcgcgag tcggagccga ccgccggctc cccagggcgc
      301 gtgcggcgcg ggccgcgggc agcggacgag acggcgccag tgtctggccg cagaggcaag
      361 ggcggcggcg gcccggaggc cgcgcccgac gtcccgagcc gccccgagcg aggcccgcgc
      421 gccagcctgg cgggctcgga cggcggcagc gcgcgctcca gcggcatcag cctgggctac
      481 gaccagcgcc acggccccgg ccccgggccg ccgtcggggg gcagcgcgcg ctccagcgtg
      541 tccagcctgg gctcccgcgg ctcagccggc gcctgtgcag acctgctgcc gcccggcgtc
      601 ggccccacgc ccgctcgctc cccggagcct gcccagttcc ccttcccatt gccgtcgctg
      661 ccgctgcccc cgggccggga gggcggcccg agtgcggccg agcggcggct ggaggcgctc
      721 acgcgggaac tggagcgcgc gctcgaggcg cgcacggcgc gagactactt tggcatttgt
      781 atcaagtgtg ggcttggcat ctacggagcg aggcaggcgt gccaggcgat ggggagcctg
      841 tatcacaccg actgcttcat ctgcgactcc tgcgggagac ggctccgcgg gaaggccttc
      901 tataacgtgg gtgagaaagt gtactgccag gaggacttcc tgtactccgg gttccagcaa
      961 acagctgaca agtgtagcgt gtgtggacac ctcatcatgg agatgatcct gcaggctctt
     1021 ggcaagtcct accacccggg ctgcttccgc tgttcagtgt gcaacgagtg cctagatggg
     1081 gttcccttca ctgtggatgt ggagaacaac atttactgcg ttcgagacta tcatacggtg
     1141 tttgcaccaa aatgtgcctc ctgcgcccgc cccatcctcc ctgcacaggg ctgtgagaca
     1201 accattcgtg tggtgtccat ggacagagac taccatgtgg agtgttacca ctgtgaggac
     1261 tgtgggatgc agctgagtgg ggaggaggga cgccgctgct accccctgga aggtcacctg
     1321 ctctgccgtc gttgccacct gaggcgcctt ggacagggtc cacttccctc gcctgctgtg
     1381 catgtgactg agctctgaaa agcagccttc agagagagga gtgacccaca ctccccctcc
     1441 cccgctgctg tcccttccgc gggggccgga cccccgcaac caagaagcag tttctattta
     1501 ttcaccttct gtgcctcaag tcactccccc tgctggattc caggacaccc gcaccgtgga
     1561 ctaccttctc cgcctggtct cagctcccac ggcagagatc ggagggcctt agagatagat
     1621 ggtgggggac cacagagcca gggagcactg acaacctggg aaagaccacg attggccttg
     1681 atggctattt tcagctgaat tctcctactc tctggatcct ggcttggggt gcttttctag
     1741 tgtccccagc ctcagaagac cccggagcag agagggggtg aggggggctc tctgtgacct
     1801 tgccagggag catcggtgca cactgtatca ggctcactac caaagcatat gatttgactt
     1861 aaattaagtt tttcccttct ggaggatgtt tgcattttct ttaaaagaat atagttttct
     1921 tctagaactt gga
//
