LOCUS       NM_001007616            2292 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus WD repeat and SOCS box-containing 2 (Wsb2),
            transcript variant 1, mRNA.
ACCESSION   NM_001007616 XM_213791
VERSION     NM_001007616.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2292)
  AUTHORS   Girard,A., Sachidanandam,R., Hannon,G.J. and Carmell,M.A.
  TITLE     A germline-specific class of small RNAs binds mammalian Piwi
            proteins
  JOURNAL   Nature 442 (7099), 199-202 (2006)
   PUBMED   16751776
REFERENCE   2  (bases 1 to 2292)
  AUTHORS   Kile,B.T., Schulman,B.A., Alexander,W.S., Nicola,N.A., Martin,H.M.
            and Hilton,D.J.
  TITLE     The SOCS box: a tale of destruction and degradation
  JOURNAL   Trends Biochem Sci 27 (5), 235-241 (2002)
   PUBMED   12076535
  REMARK    Review article
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On Dec 29, 2022 this sequence version replaced NM_001007616.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC081901.1, SRR26360194.865938.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760400,
                                           SAMEA5760475 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                JAXUCZ010000012.1  44899426-44899474   c
            50-218              JAXUCZ010000012.1  44893083-44893251   c
            219-463             JAXUCZ010000012.1  44886282-44886526   c
            464-595             JAXUCZ010000012.1  44886012-44886143   c
            596-696             JAXUCZ010000012.1  44882510-44882610   c
            697-869             JAXUCZ010000012.1  44881070-44881242   c
            870-980             JAXUCZ010000012.1  44880470-44880580   c
            981-1088            JAXUCZ010000012.1  44880256-44880363   c
            1089-2292           JAXUCZ010000012.1  44878483-44879686   c
FEATURES             Location/Qualifiers
     source          1..2292
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..2292
                     /gene="Wsb2"
                     /note="WD repeat and SOCS box-containing 2"
                     /db_xref="GeneID:288692"
                     /db_xref="RGD:1359599"
     exon            1..49
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..1251
                     /gene="Wsb2"
                     /note="isoform 1 is encoded by transcript variant 1; WD
                     repeat and SOCS box-containing protein 2; WD SOCS-box
                     protein 2"
                     /codon_start=1
                     /product="WD repeat and SOCS box-containing protein 2
                     isoform 1"
                     /protein_id="NP_001007617.1"
                     /db_xref="GeneID:288692"
                     /db_xref="RGD:1359599"
                     /translation="MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWS
                     QGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDSKGRGSLKEKTLDCGQIVWGLAFSPW
                     PSPPSRKLWLRHHPQVPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLS
                     FTPNGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGE
                     KSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGERLRS
                     LHHTQLEAPVDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMT
                     NGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRRFLTTYQVLALPIP
                     KKMKDFLTYRTL"
     exon            50..218
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            219..463
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            464..595
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            596..696
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            697..869
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            870..980
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            981..1088
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
     exon            1089..2292
                     /gene="Wsb2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaggcgcccg ccgcctgggg cgggccgcgc gtcctcatgg aggccggaga ggaaccccta
       61 ctgctggctg aactcaagcc cgggcgcccc caccagtttg attggaagtc aagctgtgaa
      121 acctggagtg tggccttttc tccagatggt tcctggttcg cctggtctca aggacactgc
      181 gtggtcaagc tggtaccctg gcccttagag gagcagttta tccctaaagg attcgaagcc
      241 aaaagccgaa gcagcaagaa tgattcaaaa ggacggggca gtctgaagga gaagacgctg
      301 gactgtggcc agattgtatg ggggttggcc ttcagcccat ggccctctcc acccagcagg
      361 aaactctggc tccgtcacca tccccaggtg cctgatgtct cctgcctgat cctggccaca
      421 ggtctcaacg acggacagat caagatttgg gaggtgcaga cagggctcct gctgctgaat
      481 ctttctggcc accaggatgt tgtgagagat ctgagcttca cgcccaatgg cagcttgatt
      541 ttggtctctg catcccggga taagactctt cgcatttggg acctgaataa gcacggtaag
      601 cagatccagg tgctgtccgg ccatctgcag tgggtttact gctgctccat ctcccctgac
      661 tgcagcatgc tgtgctctgc cgctggtgag aagtcggtct ttctgtggag catgcgatct
      721 tacacactaa tccggaaact agaaggccac caaagcagtg ttgtctcctg tgacttctct
      781 cccgattccg ccttgctcgt tacagcttcg tatgacacca gtgtgatcat gtgggacccc
      841 tacaccggcg agaggctgag gtcacttcat cacactcagc tcgaagctcc cgtggatgac
      901 agtgatgtcc acatgagctc cctgcggtct gtgtgcttct cccctgaagg cctatatctt
      961 gctacagtgg cagacgacag gctcctcagg atctgggctc tggaactgaa ggctcccgtt
     1021 gcctttgctc ctatgaccaa tggtctctgc tgcacattct tcccacacgg tggagttatt
     1081 gccacaggga cgagagatgg ccatgtccag ttctggacgg ctccgcgagt cctgtcctca
     1141 ctgaagcact tatgcaggaa agccctccga cgtttcctga ctacgtatca agtcctagca
     1201 ctgccaatcc ccaagaagat gaaagacttc ctcacgtaca ggactttgta gcagtgccag
     1261 cccccatctc ctgcagcaga accagtacaa gggactggcg aggatggagc caggcagacc
     1321 acgctggacc agtgtggacc ttcctcccca tggcatgtgc aagtaggtct gagtgatccc
     1381 acttccgtgg tgccagcctt acctcgcctt cgtccgttgt gagcagcctt tgtcagtcta
     1441 gttgtgttga agccaagtgc agttgtggaa gtcgtgtggg taataaaagc aagcaggctc
     1501 cagagcctct ctggtggtgg ccaagtccac actcccttaa ctgggaagtg cctgccacgt
     1561 agggtccctg cagcctattt ccaggcagca gctgcatggt ttgaagttcc ctctgttctg
     1621 gtgagaggga ctttgatatt tgcttccgta ctcagctgca cacaaactgg gctgtgctcc
     1681 tcagcaaaca ctagccggct tttattttcc tttcaacagt ggtgtgcatg tatagaaaag
     1741 gacaagcgag tatatcagat catacaaggt gttcctcaac tgcatgacgg ccagacggcc
     1801 actatcagca tcatatttat gtgttttctc agcagatact aaggtacaac tgtgttttct
     1861 caattgtctc taagaaccag ggttcctaag tggcccagtt gtgagccaag tcttagccgt
     1921 gtggagtcag tgttgacatc actggcttgt gctgtcacgt gcgttgtctc tgctgcttga
     1981 cctcacggga tttaccctcc aactccaact gcccagaaca gacagcccct tccaagcacc
     2041 gttctttggc agcggtagca gctacctatt caacacgcct cacacaaaat ctgccttagg
     2101 aaagttaata tattttaaat tattttaaaa gaaacagcat cctactcttg ggcctttctt
     2161 aattgatgct ttatggaggc agtgctaaca ttgcagtgtg cacaggatcc cctctgttat
     2221 ttgaagaagt acattgcaaa tgaggctttc attgaaggga gaaaagagaa aaagaaaaag
     2281 gaaaaaaaaa aa
//
