LOCUS       NM_172332               2640 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus WRN helicase interacting protein 1 (Wrnip1),
            mRNA.
ACCESSION   NM_172332
VERSION     NM_172332.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Grolimund,L., Aeby,E., Hamelin,R., Armand,F., Chiappe,D.,
            Moniatte,M. and Lingner,J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   2  (bases 1 to 2640)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
REFERENCE   3  (bases 1 to 2640)
  AUTHORS   Mano,Y., Takahashi,K., Ishikawa,N., Takano,A., Yasui,W., Inai,K.,
            Nishimura,H., Tsuchiya,E., Nakamura,Y. and Daigo,Y.
  TITLE     Fibroblast growth factor receptor 1 oncogene partner as a novel
            prognostic biomarker and therapeutic target for lung cancer
  JOURNAL   Cancer Sci 98 (12), 1902-1913 (2007)
   PUBMED   17888034
REFERENCE   4  (bases 1 to 2640)
  AUTHORS   Tsurimoto,T., Shinozaki,A., Yano,M., Seki,M. and Enomoto,T.
  TITLE     Human Werner helicase interacting protein 1 (WRNIP1) functions as a
            novel modulator for DNA polymerase delta
  JOURNAL   Genes Cells 10 (1), 13-22 (2005)
   PUBMED   15670210
REFERENCE   5  (bases 1 to 2640)
  AUTHORS   Kawabe,Yi., Branzei,D., Hayashi,T., Suzuki,H., Masuko,T., Onoda,F.,
            Heo,S.J., Ikeda,H., Shimamoto,A., Furuichi,Y., Seki,M. and
            Enomoto,T.
  TITLE     A novel protein interacts with the Werner's syndrome gene product
            physically and functionally
  JOURNAL   J Biol Chem 276 (23), 20364-20369 (2001)
   PUBMED   11301316
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC098652.1.
            
            On Jul 13, 2005 this sequence version replaced NM_172332.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC098652.1, AY136827.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132292, SAMD00155316
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p12"
     gene            1..2640
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /note="WRN helicase interacting protein 1"
                     /db_xref="GeneID:282835"
                     /db_xref="RGD:628836"
     exon            1..992
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     CDS             186..2168
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /EC_number="3.6.1.3"
                     /note="werner helicase-interacting protein 1; Werner
                     syndrome homolog interacting protein; Werner helicase
                     interacting protein 1"
                     /codon_start=1
                     /product="ATPase WRNIP1"
                     /protein_id="NP_758835.1"
                     /db_xref="GeneID:282835"
                     /db_xref="RGD:628836"
                     /translation="MEVSGPEDDPFLSQLHQVQCPVCQQMMPAAHINSHLDRCLLLHP
                     AGHAEPAAGPHRAGERAKGPSPPGAKRRRLSESSALKQPATPTAAESSEGEGEEGDDG
                     GETESRESYDAPPTPSGARLIPDFPVARSSSPARKGLGKRPAAAAAAGSASPRSWDET
                     EAQEEEEAGVDGDGDADVDGEDDPGHWDADAADASFGVSAGRAHPRALPAEEIRQMLE
                     GKPLADKMRPDTLQDYIGQSRAVGQETLLRSLLETNEIPSLILWGPPGCGKTTLAHII
                     ANNSKKHSIRFVTLSATNAKTNDVRDVIKQAQNEKSFFKRKTILFIDEIHRFNKSQQD
                     TFLPHVECGTITLIGATTENPSFQVNTALLSRCRVIVLEKLPVEAMVTILMRAINSLG
                     IHVLDSSRPTDPLSHSSNCSSEPSVFIEDKAVDTLAYLSDGDARTGLNGLQLAVLARL
                     SSRKMFCKKSGQTYSPSRVLITENDVKEGLQRSHILYDRAGEEHYNCISALHKAMRGS
                     DQNASLYWLARMLEGGEDPLYVARRLVRFASEDIGLADPSALAQAVAAYQGCHFIGMP
                     ECEVLLAQCVVYFARAPKSIEVYSAYNNVKACLRSHQGPLPPVPLHLRNAPTRLMKDL
                     GYGKGYKYNPMYSEPVDQDYLPEELRGVDFFKQRRC"
     exon            993..1184
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     exon            1185..1426
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     exon            1427..1656
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     exon            1657..1812
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     exon            1813..1892
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
     exon            1893..2614
                     /gene="Wrnip1"
                     /gene_synonym="Whip; Wrnip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgcgggccga aggcgagttg acgcgggagc tcgggacgtg aggcatgagc ggcgccctcc
       61 ctcggcccgt gcgtgtcttg ctccctaccc gcgcgagggt cgcgcggcac ggggcctagc
      121 ggcgggcatc cgcgttctca ggggcaggtg cagtcgcacg ggcgtcaggg agggcagctg
      181 ctaccatgga ggtgagcggg ccggaggacg accccttcct gtcgcagctg caccaggtgc
      241 aatgcccagt gtgccagcag atgatgcccg ccgcgcatat caactcgcac ctggaccgct
      301 gcctactgct gcaccctgcg gggcacgcgg agccagcggc cgggcctcat cgcgctgggg
      361 agcgggctaa ggggccctcg ccacccggcg ccaagaggcg tcgactgtcg gagagctcgg
      421 cgctgaaaca gcctgccacc ccgacggcgg ccgaaagcag cgaaggcgag ggcgaggagg
      481 gtgacgacgg cggcgagact gagagccgtg agagctacga cgcaccgccc acgcccagcg
      541 gtgcgcgcct catcccggac ttcccggttg cccgctccag cagcccagct agaaagggtt
      601 tggggaagag gccagcggct gcagccgcgg cgggcagtgc atccccgcgc agctgggatg
      661 agacggaggc gcaggaagag gaggaggcgg gggtggacgg cgatggcgac gcggacgtgg
      721 acggtgagga cgatcctggg cattgggatg cggacgccgc cgatgcttcg ttcggagtca
      781 gcgcgggtcg cgcacatcct cgggcactgc cggctgaaga aatccgacag atgctggagg
      841 gcaagccact ggctgataag atgcgtcccg atacgctgca ggactacatc gggcagagta
      901 gggcggtagg gcaggagacg ctgctccgct cgctattgga aaccaacgag atcccctcgc
      961 tcatcctgtg gggcccacca ggttgcggta agaccacctt ggcacacatc atagccaaca
     1021 acagcaagaa gcacagcata aggtttgtga cattatctgc aacaaatgcc aagacaaatg
     1081 acgtgaggga tgtcataaag caagctcaga atgaaaagag ctttttcaaa aggaaaacca
     1141 tcctttttat tgatgagatt catcgtttca ataaatctca gcaggacact ttccttcctc
     1201 acgtggaatg tgggacaatc acgctgattg gcgcaaccac tgagaatcct tccttccaag
     1261 tcaacaccgc acttctgagc cgctgtcggg taattgttct tgagaaactt ccagtagagg
     1321 caatggtgac gattttaatg agagcaatca actcactggg aatccatgtg ctagactcta
     1381 gccgtcctac tgaccctctg agccacagca gcaactgcag ctctgagccc tcggtcttca
     1441 tagaagataa agcagtggac actctggctt acctcagtga tggtgatgcc cggactggct
     1501 taaatggact gcaactggca gtgctggcca ggttaagctc tagaaagatg ttttgtaaga
     1561 agagcggtca aacctattct cctagtcgag ttctgatcac tgagaatgat gtgaaagaag
     1621 gtctacagcg gtcccacatt ttatatgacc gagcaggaga agagcactac aactgcatct
     1681 ctgccctaca caaggctatg cgtggctctg accagaatgc ttccctgtat tggctggccc
     1741 ggatgcttga gggaggggag gacccactct atgtggccag gaggctggta aggtttgcca
     1801 gcgaggacat tggtctggca gatccgtcag cactagccca agcggttgct gcctaccaag
     1861 gctgtcactt tataggcatg cccgagtgtg aggtgcttct ggcccagtgt gtggtgtatt
     1921 ttgccagagc cccaaagtcc attgaggtgt acagtgccta taacaatgta aaagcctgtc
     1981 tgcggagcca ccaggggccc ctgcctcctg tacccctgca cctgaggaat gcgcccacca
     2041 ggctgatgaa ggatttgggt tatggcaaag gctacaagta taaccccatg tacagcgagc
     2101 ctgtggacca ggactacctg cctgaggaac tgagaggagt tgacttcttc aagcaaaggc
     2161 ggtgttgact cttgggccat gagtaggatg cttgtatctt gaggaaggcc aaaagtcact
     2221 ggatcttgga gttggttgcc tggggaaagt taaaatagac caacattttg tgccagaaac
     2281 taagggttcc atagatggag gtggttactt cagctaaatg tgtaccattg aaattgtgtt
     2341 catttgcact ctgtgcaatg attatgctta tgaaaatacc tggcagcttt gtgcaattaa
     2401 tgttataagg aattatctat tttgtcatag tatttaagtc ataatgtcat ttcaaaattc
     2461 tgttcagtag gctttttttt cttttaaaaa atgtatattc tgggtagtta caattggtaa
     2521 gagaaaatgt aattgtgatt taatactgca tagtgatttg ggtatttttt ttatatgcaa
     2581 aggtcttatg agccaataaa actatttcaa agtaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
