LOCUS       NM_001106359            3365 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus Wnt family member 8B (Wnt8b), mRNA.
ACCESSION   NM_001106359 XM_001057370 XM_006231442 XM_219959
VERSION     NM_001106359.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Voloshanenko,O., Gmach,P., Winter,J., Kranz,D. and Boutros,M.
  TITLE     Mapping of Wnt-Frizzled interactions by multiplex CRISPR targeting
            of receptor gene families
  JOURNAL   FASEB J 31 (11), 4832-4844 (2017)
   PUBMED   28733458
REFERENCE   2  (bases 1 to 3365)
  AUTHORS   Gao,H., Zhang,Z.B., Jiang,Z.J., Wang,D.J., Huang,Y. and Wang,W.L.
  TITLE     [Mutation and expression of WNT8b gene and SHH gene in Hirschsprung
            disease]
  JOURNAL   Zhonghua Wei Chang Wai Ke Za Zhi 13 (10), 758-761 (2010)
   PUBMED   20972907
REFERENCE   3  (bases 1 to 3365)
  AUTHORS   Fotaki,V., Larralde,O., Zeng,S., McLaughlin,D., Nichols,J.,
            Price,D.J., Theil,T. and Mason,J.O.
  TITLE     Loss of Wnt8b has no overt effect on hippocampus development but
            leads to altered Wnt gene expression levels in dorsomedial
            telencephalon
  JOURNAL   Dev Dyn 239 (1), 284-296 (2010)
   PUBMED   19890917
REFERENCE   4  (bases 1 to 3365)
  AUTHORS   van Amerongen,R., Mikels,A. and Nusse,R.
  TITLE     Alternative wnt signaling is initiated by distinct receptors
  JOURNAL   Sci Signal 1 (35), re9 (2008)
   PUBMED   18765832
  REMARK    Review article
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On or before Dec 30, 2022 this sequence version replaced
            XM_006231442.4, NM_001106359.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.8960.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-196               JAXUCZ010000001.1  253303369-253303564
            197-230             JAXUCZ010000001.1  253319714-253319747
            231-369             JAXUCZ010000001.1  253320444-253320582
            370-495             JAXUCZ010000001.1  253321400-253321525
            496-638             JAXUCZ010000001.1  253322191-253322333
            639-3365            JAXUCZ010000001.1  253322498-253325224
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q54"
     gene            1..3365
                     /gene="Wnt8b"
                     /note="Wnt family member 8B"
                     /db_xref="GeneID:293990"
                     /db_xref="RGD:1307644"
     exon            1..196
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
     CDS             132..1184
                     /gene="Wnt8b"
                     /note="protein Wnt-8b; wingless related MMTV integration
                     site 8b; wingless-type MMTV integration site family,
                     member 8B"
                     /codon_start=1
                     /product="protein Wnt-8b precursor"
                     /protein_id="NP_001099829.2"
                     /db_xref="GeneID:293990"
                     /db_xref="RGD:1307644"
                     /translation="MFLMKPVCVLLVTCVLHRSHAWSVNNFLMTGPKAYLVYSSSVAA
                     GAQSGIEECKYQFAWDRWNCPERALQLSSHGGLRSANRETAFVHAISSAGVMYTLTRN
                     CSLGDFDNCGCDDSRNGQLGGQGWLWGGCSDNVGFGEAISKQFVDALETGQDARAAMN
                     LHNNEAGRKAVKGTMKRTCKCHGVSGSCTTQTCWLQLPEFREVGAHLKEKYHAALKVD
                     LLQGAGNSAAGRGAIADTFRSISTRELVHLEDSPDYCLENKTLGLLGTEGRECLRRGR
                     ALGRWERRSCRRLCGDCGLAVEERRAETVSSCNCKFHWCCAVRCEQCRRRVTKYFCSR
                     AERPPRGAAHKPGKNP"
     exon            197..230
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
     exon            231..369
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
     exon            370..495
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
     exon            496..638
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
     exon            639..3365
                     /gene="Wnt8b"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctccatttc accacccctt aactctgttt gggatcgctt acacaccaag gtagccatcc
       61 ctctgcctct gaggagaatg cttcccatct ctcagtttct cagatgtccg ccctgcgttt
      121 ctcagaagac catgtttctc atgaagcctg tgtgcgttct tctagtcacc tgtgtccttc
      181 accgcagtca cgcctggtca gtgaacaatt tcctgatgac tggaccaaag gcttacctgg
      241 tctactccag cagtgtggca gctggcgccc agagcgggat tgaagaatgt aaataccagt
      301 ttgcttggga ccgctggaat tgccctgaga gagccttaca gctgtccagc catggtggac
      361 ttcggagtgc taaccgggag acggcgtttg tgcatgctat cagttctgct ggagttatgt
      421 acaccctgac tagaaactgc agccttggag actttgacaa ctgtggctgt gatgactccc
      481 gaaatggaca gctgggaggc caaggctggc tctggggagg ctgcagtgac aacgtgggct
      541 tcggagaggc aatttccaag cagtttgtgg acgccctaga gacaggacag gatgcccggg
      601 cagccatgaa tctgcacaac aacgaggctg gccgcaaggc ggtcaagggc accatgaaac
      661 gcacgtgtaa gtgccacggc gtgtcgggca gttgcaccac acagacctgc tggttgcagt
      721 tgccagagtt ccgggaggta ggcgcgcatc tgaaggagaa gtatcacgca gcgctcaagg
      781 tggacctgct gcagggtgcg ggcaacagcg cggctggccg cggcgccatc gccgacacct
      841 tccgttccat ctctacacgc gagctggtgc atctggagga ctccccggac tactgcctgg
      901 agaacaagac cctggggctg ctgggcaccg agggccgaga gtgtctgcgg cgcgggcgcg
      961 ccctgggccg ctgggagcgc cgcagctgcc gccggctgtg cggggactgc gggttggcgg
     1021 tggaggagcg ccgcgccgag acagtgtcca gctgcaactg caagtttcac tggtgctgcg
     1081 cagtccgctg cgagcagtgt cgccggcggg tcaccaagta cttctgcagc cgtgcggagc
     1141 ggccgccgag aggcgctgcg cacaaacctg ggaagaaccc ctaagggtat ctatccctcc
     1201 tgcctccatc cctgttcatc ccgagcttgg tttagagacc ccggaaatag agaacccaga
     1261 atgggggact caaactcccc agcccagaga tactgacagg gggaggccac agtctcccta
     1321 ccgagtgaca ctttccggat tcattcgcat ggtctttgta acccattcgt aggtctcaaa
     1381 actgttataa aattctgcaa gtttttcctg agaaaaggac gaaaacagac gagtctcctc
     1441 accccaccct accctacttt agactccagt agtcataatg ctggacctag cttatcaggg
     1501 ctagaagaag agcccccatc tcagatatgc agggtccagg gaaaagatat gggccttctc
     1561 ttgtctgtca cggatgctcc tccctcgggg tgagctagaa cttctaggcc tagactccct
     1621 gctgttgact attcaagaat ctaacacttt gtcttcatat ttcccacttg ccctggggaa
     1681 aaaacaccaa acaaaaccaa aacatcaact aaacaagaac agaaaggtaa aaaaaaggaa
     1741 gaagtaagcc tttgaatatg gggtaagagg gaacctcaga gccaaacttg cacaccaaat
     1801 attactcctc tgtgacatcg tgtcactgac agacttcagc tgagcagtga ccttcctaaa
     1861 caccaaagat actccagaca cacccaaggg gtctaggagt ggtagtggtc cgcagtggac
     1921 aggttggcaa tcattttttg cttatagtgg tgtcgaactt tgtctccttc tccacaggag
     1981 ctttgatccc ctgagctgag acaggcaaat caagtcgatt cttgcatctg tacctctaaa
     2041 gacagggcat aggaaggaga aaccaggctc taacacctgg ttctcaaata ggcaggattc
     2101 agaacattgg atgctttcct gaatacgtaa acctccccta ccccaagccc acactctgaa
     2161 actgttacta ataggatgtt cagaacctta acctttttaa tttattgcag cctgatatct
     2221 gtcccttctc ccaggtcctg aactcactga tgctgagatg ctgacagaaa agcacagcgg
     2281 aaacttaacc tctaagcttt ctcctccctc ccactctggc agaataccat ctccctgtag
     2341 ccttccttga tggcctaagt agctagcttg atttgactga ggttaatctg ccagggatta
     2401 gtaaatcacc cccataaacc ttccactaat gcactcactt gggagcccac agctcgctgc
     2461 ttccaagagt ctgaggtctc tttcttggag aggggcagtc cagcagggac ttgtttatga
     2521 catggggatc cagagaacag aagagcccag atcttcccca tagctgctct ttgctctagg
     2581 ctagtcctgg gtgtgggtat ccacagcatt tctggagcaa ggccagtcaa attctatact
     2641 ttattcctct tctgctgaaa gtacagagct gagctcacaa tgccaaagcc ccagccaggg
     2701 gccaccccgg aagaatgcaa tgcctctgcc gcagcctggt cagacctctg tgcatcttct
     2761 ggtcctattg aaactttgaa ggagggagtg tttctcttct tcagcccggg acaaacttcc
     2821 cttcccttta gggtctcttg cctgtgcctt ctgagtctcc ccagctcccc ctttcctaat
     2881 cttgcagccg tggctgtcaa tcccgggtct cacccgacat ttgcacactt atagtgtaca
     2941 gaagaaaacc cagcaatgca atgaaaacca taaaggttcc gcattgggac ggtaagctgc
     3001 atttcccagg gccctcagca taaaggtgga ggcattgtgt ttccatgctc agaactttaa
     3061 agttggactc caaatgcctc aggctgtcat ttcatcccca gattactttg tttgccaaat
     3121 gggtacgagt gacatccagt tcatcccact tctatagcga acatgctccc ctacccatgt
     3181 actacgcctt catgcctttg ttcgagcaat aaacgccgga gtggagacag ctgacaacat
     3241 gcaagcatcc ctcagttcat ggcttcctgt cctgcactaa atcactgagg ccacgcggac
     3301 aactccagag ctgctgactg ggagggaaga ctagacgtcc ctagggtcag ctagtcaaac
     3361 tttaa
//
