LOCUS       NM_001191556            6450 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus WNK lysine deficient protein kinase 2 (Wnk2),
            mRNA.
ACCESSION   NM_001191556 XM_002728461
VERSION     NM_001191556.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6450)
  AUTHORS   Zheng,Y., Wang,H.Q., Guo,H.X., Xie,H.L., Zhang,W.D., Han,D.X.,
            Jiang,H., Yuan,B. and Zhang,J.B.
  TITLE     CircRNA-WNK2 Acts as a ceRNA for miR-328a-3p to Promote AANAT
            Expression in the Male Rat Pineal Gland
  JOURNAL   Endocrinology 163 (2) (2022)
   PUBMED   34918065
  REMARK    GeneRIF: CircRNA-WNK2 Acts as a ceRNA for miR-328a-3p to Promote
            AANAT Expression in the Male Rat Pineal Gland.
REFERENCE   2  (bases 1 to 6450)
  AUTHORS   Bhuiyan,M.I.H., Song,S., Yuan,H., Begum,G., Kofler,J., Kahle,K.T.,
            Yang,S.S., Lin,S.H., Alper,S.L., Subramanya,A.R. and Sun,D.
  TITLE     WNK-Cab39-NKCC1 signaling increases the susceptibility to ischemic
            brain damage in hypertensive rats
  JOURNAL   J Cereb Blood Flow Metab 37 (8), 2780-2794 (2017)
   PUBMED   27798271
REFERENCE   3  (bases 1 to 6450)
  AUTHORS   Serysheva,E., Berhane,H., Grumolato,L., Demir,K., Balmer,S.,
            Bodak,M., Boutros,M., Aaronson,S., Mlodzik,M. and Jenny,A.
  TITLE     Wnk kinases are positive regulators of canonical Wnt/beta-catenin
            signalling
  JOURNAL   EMBO Rep 14 (8), 718-725 (2013)
   PUBMED   23797875
  REMARK    Erratum:[EMBO Rep. 2013 Sep;14(9):845]
REFERENCE   4  (bases 1 to 6450)
  AUTHORS   Rinehart,J., Vazquez,N., Kahle,K.T., Hodson,C.A., Ring,A.M.,
            Gulcicek,E.E., Louvi,A., Bobadilla,N.A., Gamba,G. and Lifton,R.P.
  TITLE     WNK2 kinase is a novel regulator of essential neuronal
            cation-chloride cotransporters
  JOURNAL   J Biol Chem 286 (34), 30171-30180 (2011)
   PUBMED   21733846
REFERENCE   5  (bases 1 to 6450)
  AUTHORS   Moniz,S., Verissimo,F., Matos,P., Brazao,R., Silva,E.,
            Kotelevets,L., Chastre,E., Gespach,C. and Jordan,P.
  TITLE     Protein kinase WNK2 inhibits cell proliferation by negatively
            modulating the activation of MEK1/ERK1/2
  JOURNAL   Oncogene 26 (41), 6071-6081 (2007)
   PUBMED   17667937
  REMARK    Erratum:[Oncogene. 2008 Jan 3;27(1):155. Kotevelets, L [corrected
            to Kotelevets, L]]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000017.1.
            
            On Jul 17, 2010 this sequence version replaced XM_002728461.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMEA5760386,
                              SAMEA5760393 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-761               JAXUCZ010000017.1  15710657-15711417
            762-934             JAXUCZ010000017.1  15752841-15753013
            935-1155            JAXUCZ010000017.1  15754023-15754243
            1156-1313           JAXUCZ010000017.1  15759840-15759997
            1314-1402           JAXUCZ010000017.1  15763273-15763361
            1403-1622           JAXUCZ010000017.1  15764537-15764756
            1623-1914           JAXUCZ010000017.1  15772116-15772407
            1915-2114           JAXUCZ010000017.1  15775477-15775676
            2115-2270           JAXUCZ010000017.1  15778672-15778827
            2271-2462           JAXUCZ010000017.1  15779212-15779403
            2463-3002           JAXUCZ010000017.1  15780549-15781088
            3003-3296           JAXUCZ010000017.1  15784429-15784722
            3297-3346           JAXUCZ010000017.1  15785183-15785232
            3347-3515           JAXUCZ010000017.1  15786024-15786192
            3516-3632           JAXUCZ010000017.1  15786261-15786377
            3633-3803           JAXUCZ010000017.1  15789014-15789184
            3804-3849           JAXUCZ010000017.1  15789298-15789343
            3850-3969           JAXUCZ010000017.1  15789897-15790016
            3970-4790           JAXUCZ010000017.1  15795942-15796762
            4791-4866           JAXUCZ010000017.1  15797019-15797094
            4867-4955           JAXUCZ010000017.1  15799065-15799153
            4956-5635           JAXUCZ010000017.1  15799251-15799930
            5636-5850           JAXUCZ010000017.1  15802263-15802477
            5851-5895           JAXUCZ010000017.1  15810768-15810812
            5896-6134           JAXUCZ010000017.1  15812278-15812516
            6135-6246           JAXUCZ010000017.1  15815956-15816067
            6247-6450           JAXUCZ010000017.1  15818666-15818869
FEATURES             Location/Qualifiers
     source          1..6450
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="17"
                     /map="17p14"
     gene            1..6450
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /note="WNK lysine deficient protein kinase 2"
                     /db_xref="GeneID:306811"
                     /db_xref="RGD:1307284"
     exon            1..761
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     CDS             81..6272
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /EC_number="2.7.11.1"
                     /note="kinase deficient protein"
                     /codon_start=1
                     /product="serine/threonine-protein kinase WNK2"
                     /protein_id="NP_001178485.1"
                     /db_xref="GeneID:306811"
                     /db_xref="RGD:1307284"
                     /translation="MDGDGGRRDAPGALMEAGRGTGSAGMAEPRARAARLGPQRFLRR
                     SVVESDQEEPPGLEAAETPSAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAPAAPA
                     APPGSPSAPSDPGPERAGTQEPSPDPTTASAAATPVPDGGPRQEEAPAPTQEDTGATE
                     AKPEPGRARKDEPEEEEDDEDDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETW
                     VEVAWCELQDRKLTKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSAKGKRCIVLVTE
                     LMTSGTLKTYLKRFKVMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGP
                     TGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATS
                     EYPYSECQNAAQIYRKVTCGIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSH
                     AFFAEDTGVRVELAEEDHGRKSTIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPD
                     EVAQEMIDSGFFHESDVKIVAKSIRDRVALIQWRRERIWPALQSQEPKDTGSPDKARG
                     LPAPLQVQVTYHAQSGQPGQPEPEEPEADQHLLPPTLPASVTSLASDSTFDSGQGSTV
                     YSDSQSSQHSMVLSSLVDTAPTPASCVCSPPVSEGPGLTHSLPKLGAFQQPAAVPGLS
                     VGPVPPPARPPLLQQHFPEPSMSFTPVLPPPSTPVPTGPSQPAPPVQQPLPMAQPPTL
                     PQVLAPQPMGTVQPVPSHLPPYLAPTSQVVAPAQLKPLQMPQPPLQPLAQVPPQMPQM
                     PVVPPITPLAGLDGLPQTLADLPAANVAPVPPPQYFSPAVILPSLTTPLPTSPALPLQ
                     AVKLPHPPGAPLAVPCQTIVPNAPAAIPLLAVAPQGVAALSIHPAVAQIPAQIPAQPV
                     YPAAFPGMVPGDVPPSPHHTVQSLRATPPQLASSVPPQSVQPSVVHLPEQAAPSAASG
                     TQVLLGHPPSYTTDVAAPVSAVSLPPAVLSPPLPDTLLPTVPELLPKLPSSLAPTVVA
                     ASQSVPTQTSTLLPPTNPPLPTGPAVAGPCPAVQLTVEAAQEEQVSQDKPPGPPQSCE
                     SLGGSDVTSGRDLSDNCEGTFGTGRLEGRAARKHHRRSTRARSRQERASRPRLTILNV
                     CNTGDKMVECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILPAERETFIEQMKD
                     VMDKAEDMLSEDTDADHGSDTGTSPPHLGTCGLTTGEENGQSQANAPVYQQNVLHTGK
                     RWFIICPVAEHPAADTSESSPPLPLSSLQPEASQDPAPYPDQLSLTDKPSFPAAQQLL
                     SQAGSSNPPGGASAPTAPSSPPVTSVMPAAPATSTVPESAAGTAMQAGGPGTHQGPAS
                     VHETLHPLAETHRAQGAAQPLSTGQGPCTPALEASHCSTGLGEPISTKEVSTQGGTLS
                     ASMPEPSPPTGAVQSVPSQPPPPLPITVGTIGLAAPQLPSPPLGPTAPPPPPSALESD
                     GEGPPPRVGFVDNTIKSLDEKLRTLLYQEHVPTSSASAGTPLEANDRDFTLEPLRGDL
                     PSALSDKTPSLTQQSQPSLEKSETAPAGWALAPREQGASSSMTAESSSSNTLGCDSDT
                     GQVASDSPTAPSVPQDTSVSSVPTHMDPKDQNGSAPRETLVAPMQSCPGTFTEGSPAQ
                     LRGVRDSGSPHKRPGQQDSSSPAKTVGRFSVVSTQDEWTLASPHSLRYSAPPDVYLDE
                     IPSSPEVKLAVRRVQTASSIEVGVEEPASSDSGDECPRRRTQVQKQSSLPGSGGVASD
                     FVKKATAFLHRSSRAGSLGPETPSRAGVKVPTISITSFHSQSSYISSDNDSEFEDADI
                     KKELRSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNVGFFHTAPPMGRRRKTSK
                     SKLKAGKLLNPLVQQLKVVASSTGSALKRLCLGKEHSSRSSTSSLAPGPEPGPQPTLH
                     VQAQVNNSNNKKGTFTDDLHKLVDEWTTKTVGAAQVKPTLNQLKQTQKLHDMEASGEA
                     RATSVPRGGVATSCLAPAPGPLSSTAIPGVTPALPVPTPDPESEKPD"
     exon            762..934
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1155
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            1156..1313
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            1314..1402
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            1403..1622
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1914
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            1915..2114
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            2115..2270
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            2271..2462
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            2463..3002
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3003..3296
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3297..3346
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3347..3515
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3516..3632
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3633..3803
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3804..3849
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3850..3969
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            3970..4790
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            4791..4866
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            4867..4955
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            4956..5635
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            5636..5850
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            5851..5895
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            5896..6134
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            6135..6246
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
     exon            6247..6450
                     /gene="Wnk2"
                     /gene_synonym="RGD1307284"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcgctgtctc atcccgcggc ccaggcaggt gcggcggggc tggcgctcac gcggggcccg
       61 tgtgtccttg gcccgcagag atggacggcg atggcggccg ccgagacgcc cccggcgcgt
      121 tgatggaggc cgggcgcggc acggggtcgg cgggcatggc ggagccgcga gcgagggcgg
      181 cgcggctcgg gccccagcgc ttcctgcggc gcagcgtggt ggagtcggac caggaggagc
      241 cgccgggcct ggaggcggcc gagacgccga gcgcgcagcc cccacagccc ctgcagcgca
      301 gggtgcttct actctgcaag acgcgccgcc tcatcgcgga gcgcgcccgg ggccgccccg
      361 ccgcgcccgc gcctgccgcg cccgctgcgc ctcctggctc cccgagtgcc ccctcggacc
      421 ctggcccgga gcgagcgggc acgcaggagc ccagcccaga tcccaccacc gcgtcagctg
      481 cagccacccc ggtccccgac ggcggcccgc ggcaggagga ggcgcccgcc ccaacccagg
      541 aggacactgg agctaccgag gcaaagccgg agcccgggcg cgcacgcaag gatgaacctg
      601 aggaggagga ggacgatgag gacgacctca aggctgtggc tacctctttg gacggccgct
      661 tcctcaagtt cgacatcgag ctgggccggg gctccttcaa gacggtctac aaggggctgg
      721 acacggagac ctgggtggag gtagcatggt gtgaactgca ggaccggaag ctcaccaaac
      781 tcgaacggca gcggttcaaa gaggaggcag agatgctgaa aggtctacag caccccaaca
      841 ttgtgcgctt ctatgacttc tgggagtcca gtgccaaggg caaacgatgt attgtgctgg
      901 tgacggagct gatgacctca gggacattga agacgtacct gaagcggttc aaggtgatga
      961 agcccaaggt actgagaagc tggtgccggc agatcctgaa gggcctgttg tttctgcaca
     1021 caaggactcc ccccatcatc caccgagacc tcaagtgtga caacatcttc atcaccgggc
     1081 ccaccggctc cgtgaagatt ggcgacttgg gtctggccac cctgaaaaga gcatcttttg
     1141 ccaaaagtgt aataggtacc cccgagttca tggcacccga aatgtacgag gagcattacg
     1201 acgagtcggt tgatgtctac gctttcggga tgtgcatgct ggagatggcc acctcagagt
     1261 atccctattc ggagtgccag aacgccgccc agatctatcg caaggtcacc tgtggcatca
     1321 agccggccag ctttgagaag gtgcatgatc ctgagatcaa ggagatcatc ggagagtgca
     1381 tctgcaagaa caaagaggag aggtacgaga ttaaggacct gctgagccac gccttcttcg
     1441 cggaagacac gggcgtccgg gtggaacttg cagaggagga ccatggcagg aagtctacca
     1501 tagccctgcg gctttgggta gaagacccca agaagctgaa gggcaagccc aaagacaatg
     1561 gagcgataga gtttaccttt gacctggaga aggagacccc cgacgaggtg gcccaagaaa
     1621 tgattgattc cggatttttc catgagagtg atgtgaagat tgtggccaag tccatccggg
     1681 accgggtagc actcattcaa tggcgtcgtg agaggatctg gcctgcactg cagtctcagg
     1741 agccaaagga cacaggcagc cctgacaagg ccaggggtct gccagcaccc ctgcaggtcc
     1801 aggtgaccta ccatgcacag agcgggcagc ctggacagcc agaacctgag gagcctgagg
     1861 cggaccagca tctcctgccc cctaccttgc cagctagcgt tacctcctta gcctcggaca
     1921 gcacctttga cagtggccag ggctctaccg tgtactcgga ctcccagagc agccagcata
     1981 gcatggtgct cagctccctc gtggacacag ctccaacccc agcctcgtgc gtatgcagcc
     2041 cccctgtgag tgaggggccc ggcttgacac acagcctgcc taaactaggg gccttccagc
     2101 agccagccgc tgtgcctggc ctatcagtgg gccctgtgcc accccctgcc cgccctccac
     2161 tcctccagca gcattttcca gagccttcca tgagcttcac ccctgtgctg ccaccaccca
     2221 gcacccctgt gcccacgggc ccaagccagc cagcaccccc agttcagcag cctcttccaa
     2281 tggcccagcc acctaccctg ccgcaggtcc tggccccaca gcccatgggc actgtccagc
     2341 cagtgccctc tcatttgcct ccatacctgg ctccaacctc ccaggtagtg gcccctgctc
     2401 agctgaagcc tctccagatg ccacagccac ctctacaacc tcttgctcaa gtccctccgc
     2461 agatgcctca aatgcctgtg gttcccccca tcactccctt agcaggactc gacggcctcc
     2521 ctcagaccct cgctgacctg ccggctgcaa acgtggcccc tgtgccgcca cctcagtatt
     2581 tctcacctgc tgtgatcttg ccaagcctca caacgcccct gcccacatca ccggccctgc
     2641 ctctgcaggc tgtcaagctg cctcaccccc ctggggcacc cctggctgtg ccctgtcaga
     2701 ccatcgtgcc aaacgcacca gctgctatcc ccctcttggc cgtggccccg cagggtgtgg
     2761 ccgcactgtc catccatcca gcagtggccc agatcccagc ccagatccca gcccagcctg
     2821 tgtacccagc agccttccca ggaatggtac ctggagacgt ccctccctca ccccaccaca
     2881 cagtgcagag cttacgggcc acccctccac agctggcctc gtctgtgcct cctcagtctg
     2941 tccagcccag tgtcgttcat ctacctgagc aggctgctcc atctgctgcc tcagggaccc
     3001 aggtcctgct gggccaccct ccttcgtaca ccacggatgt tgctgctcca gtctctgctg
     3061 tgtccctgcc gcctgctgtc ctttcccctc ctctgccaga tactctgctg cctactgtcc
     3121 ctgagctcct gcccaagctc cccagctctc tggcccctac ggtggtcgca gcttctcaga
     3181 gtgtgcccac acagacctct acactcctcc caccaacaaa cccacctctg cccactgggc
     3241 ctgcagtcgc tggcccctgc cctgctgtcc agctgacggt ggaagcagct caagaggagc
     3301 aggtctcaca agacaaaccc ccgggccccc cacagagctg tgagagcttg ggaggttctg
     3361 atgtcacctc tggaagagat ctgagtgaca actgtgaagg cacctttgga acgggcaggc
     3421 tggagggaag ggctgcccgg aaacaccacc gtaggtccac tcgtgcacgc tcccggcagg
     3481 agagggccag ccggccccgg ctcactatcc tgaatgtgtg taacacgggg gacaagatgg
     3541 tggagtgtca gctggagacg cataaccaca agatggtgac cttcaagttt gacctcgatg
     3601 gggacgctcc agatgagatt gccacataca tggtagagca tgacttcatc ctgcccgctg
     3661 agcgagagac gtttatcgag cagatgaagg acgtcatgga caaggcagaa gatatgctca
     3721 gtgaggacac ggatgctgat catggctctg atacagggac cagccctcca cacctgggta
     3781 cctgtggtct gaccacgggg gaggagaatg gacagtccca agccaatgcc cctgtctatc
     3841 agcagaatgt cttgcacacg gggaagaggt ggtttatcat ctgtccagtg gctgagcacc
     3901 cagcagcaga cacttctgag tcatcacccc cacttcctct aagctctttg cagccagaag
     3961 ccagccaaga cccagcaccc tatccagacc agctgtcctt gacggacaaa cccagtttcc
     4021 cagctgctca gcagctcctg agccaggcag gctccagcaa ccctcctggt ggagcatcag
     4081 cccccacggc cccatcttcc cctcctgtga cttctgtaat gcccgcagca ccagccacca
     4141 gcaccgtgcc agagtcagca gcagggactg ccatgcaggc aggaggtcca gggactcatc
     4201 aaggaccagc cagtgttcat gagaccctcc acccactggc cgagacacat cgtgcccagg
     4261 gtgctgccca gccccttagc actggccaag gaccttgcac tccagctctg gaggcctctc
     4321 actgctccac aggtctggga gagcccatct caaccaagga ggtcagcact caaggaggga
     4381 ccctgtctgc ttcaatgcca gagcccagcc ctcccactgg ggctgtacaa tctgtaccga
     4441 gtcagccacc acccccactg cccatcacag tggggactat aggtctggca gctccccagc
     4501 ttcccagtcc ccctctgggg cctactgctc ccccaccacc accctcagcc ttggaatctg
     4561 atggggaagg gccaccccct agggtgggct tcgtggacaa caccatcaag agtctggatg
     4621 agaaactgcg gactctgctc taccaggagc atgtgcccac ctcctcagcc tcggctggga
     4681 cccccttgga ggcaaacgac agagacttca ccctggagcc ccttcgagga gacctcccct
     4741 cggccttgag tgacaagacc ccaagcctca cccagcagag ccagccctca ttggaaaagt
     4801 cagaaacggc tcctgcaggg tgggccctgg ccccgcggga acagggtgcg tcctcttcaa
     4861 tgacagcaga gtcctcttcc agcaacacac tgggctgtga cagtgacaca gggcaggtgg
     4921 cctcggactc ccccacagca cccagtgtcc cccaggatac ctccgtttct tccgtcccta
     4981 cgcacatgga tcccaaagat cagaatggta gtgctcccag agaaaccttg gtagcaccca
     5041 tgcagagttg cccagggacc ttcacagagg gcagcccagc ccagctgcgt ggcgtccggg
     5101 actccgggtc cccccataag cggccagggc agcaggacag cagttctcca gccaaaactg
     5161 tgggccgctt ctccgtggtc agcacacaag acgagtggac tctggcgtca cctcacagcc
     5221 tgcggtactc cgccccacct gatgtctacc tggatgagat cccctctagc cctgaggtga
     5281 agctggcagt tcgtcgagta cagacagcct cctccatcga ggttggcgtt gaggagcctg
     5341 cctccagtga ctctggggat gaatgcccaa gaaggaggac ccaggtgcag aagcagtcct
     5401 ccctgccggg gagcggtggc gtggcaagtg actttgtgaa gaaggccact gccttcctgc
     5461 acaggtcatc aagggctggc tcgctgggcc ctgagacacc cagcagggca ggtgtgaagg
     5521 tccctaccat cagtatcacc tccttccact cccagtcatc ctacatcagc agtgacaacg
     5581 actcggagtt tgaggacgca gacataaaga aggaactgcg cagcctgcgg gaaaagcacc
     5641 tgaaggaaat ctctgagcta cagagccagc agaaacagga gattgaagcc ctgtacagac
     5701 gcttgggcaa gccgctccct cccaatgtgg ggttcttcca caccgcaccc cctatgggcc
     5761 gcaggagaaa aaccagcaag agcaaattga aggcgggcaa gctgctgaat cccctggtgc
     5821 aacagctcaa ggtcgtggcc tccagcacag ggtcagccct gaagcgtctc tgcctaggca
     5881 aagaacacag cagtaggtct tccaccagca gcctggcccc aggccctgag ccaggtcccc
     5941 agcccaccct gcacgtccag gcgcaggtga acaacagcaa caacaagaag ggcaccttca
     6001 cggatgatct gcacaagctg gtggatgagt ggacaacgaa gacagtgggg gcggcccaag
     6061 tgaagcccac gctcaaccag ctgaagcaga cgcagaagct gcatgacatg gaggcctctg
     6121 gagaggctcg ggctacatct gtgcctcgag gaggagtggc aacatcgtgt ctggccccag
     6181 cacctggccc tctgtccagc acagccattc ctggagtcac cccagccctg cctgtgccca
     6241 caccagatcc tgagagtgaa aagcccgact gagccggccc gtacaccagg cctacactgc
     6301 atcatccagg cgaagaagca gcagagccca gggcggccac ccctctagtc cattcacgct
     6361 gttttgtaac cactttctaa ccattttttt attcacaatt ggaaacacaa atgtaatgca
     6421 agaataaaac atattttggg ggagacagga
//
