LOCUS       NM_001129776            1659 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus WAP, follistatin/kazal, immunoglobulin, kunitz
            and netrin domain containing 1 (Wfikkn1), mRNA.
ACCESSION   NM_001129776 XM_001060771 XM_343870
VERSION     NM_001129776.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1659)
  AUTHORS   Lee,Y.S. and Lee,S.J.
  TITLE     Regulation of GDF-11 and myostatin activity by GASP-1 and GASP-2
  JOURNAL   Proc Natl Acad Sci U S A 110 (39), E3713-E3722 (2013)
   PUBMED   24019467
REFERENCE   2  (bases 1 to 1659)
  AUTHORS   Szlama,G., Kondas,K., Trexler,M. and Patthy,L.
  TITLE     WFIKKN1 and WFIKKN2 bind growth factors TGFbeta1, BMP2 and BMP4 but
            do not inhibit their signalling activity
  JOURNAL   FEBS J 277 (24), 5040-5050 (2010)
   PUBMED   21054789
REFERENCE   3  (bases 1 to 1659)
  AUTHORS   Nishida,A.T., Kobuke,K., Kojima,K., Ito,J., Honjo,T. and Tashiro,K.
  TITLE     OC29 is preferentially expressed in the presumptive sensory organ
            region of the otocyst
  JOURNAL   Dev Dyn 231 (4), 766-774 (2004)
   PUBMED   15497143
  REMARK    GeneRIF: OC29 may have a role in the early development of the inner
            ear sensory organ, particularly in the formation of the cristae of
            the semicircular canals [OC29]
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473948.1.
            
            On or before Oct 22, 2008 this sequence version replaced
            XM_343870.3, XM_001060771.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132262,
                              SAMD00132266 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1659
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q12"
     gene            1..1659
                     /gene="Wfikkn1"
                     /gene_synonym="Oc29; RGD1565835"
                     /note="WAP, follistatin/kazal, immunoglobulin, kunitz and
                     netrin domain containing 1"
                     /db_xref="GeneID:363555"
                     /db_xref="RGD:1565835"
     CDS             1..1659
                     /gene="Wfikkn1"
                     /gene_synonym="Oc29; RGD1565835"
                     /note="WAP, kazal, immunoglobulin, kunitz and NTR
                     domain-containing protein 1; WAP, FS, Ig, KU, and
                     NTR-containing protein 1"
                     /codon_start=1
                     /product="WAP, Kazal, immunoglobulin, Kunitz and NTR
                     domain-containing protein 1 precursor"
                     /protein_id="NP_001123248.1"
                     /db_xref="GeneID:363555"
                     /db_xref="RGD:1565835"
                     /translation="MPAPQPLLPLLFAFVLIHLTSETNLLPEPGSHPGMCPNQLSPHL
                     WVDAQSTCERECTRDQDCAASEKCCTNVCGLQSCVAARFPSGGPATPETAASCEDFQC
                     PQQGSNCDIWDGQPVCRCRDRCEKEPSFTCASDGLTYYNRCYMDAEACLRGLHLHVVP
                     CKHILSWPPSSPGPPETTARPTPGAAPMPPALYNSPSPQAVHVGGTASLHCDVSGRPP
                     PAVTWEKQSHQRENLIMRPDQMYGNVVVTSIGQLVLYNAQLEDAGLYTCTARNAAGLL
                     RADFPLSVLQRATTQDRDPGVLALAECQPDTQACVGPPTPHHVLWRFDPQRGSCMTFP
                     ALKCDGAARGFETYEACQQACVRGPGDVCALPPVQGPCQGWEPRWAYSPLLQQCHPFI
                     YSGCEGNSNNFESRESCEDACPVPRTPPCRACRLKSKLALSLCRSDFAIVGRLTEVLE
                     EPEAAGGIARVALDDVLKDDKMGLKFLGTKYLEVTLSGMDWACPCPNVTVGDGPLVIM
                     GEVREGVAVLDANSYVRAASEKRVKKIVELLEKKACELLNRFQD"
     exon            1..180
                     /gene="Wfikkn1"
                     /gene_synonym="Oc29; RGD1565835"
                     /inference="alignment:Splign:2.1.0"
     exon            181..1659
                     /gene="Wfikkn1"
                     /gene_synonym="Oc29; RGD1565835"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgcctgccc cacagccact cctgcctctg ctctttgcct tcgtgctcat ccatctgacc
       61 tcggagacca acctgctgcc agagcctgga agccatcctg gcatgtgccc caaccagctc
      121 agcccccacc tgtgggtcga cgcccagagc acctgtgagc gtgagtgtac cagggaccag
      181 gactgtgcgg catctgagaa gtgctgcacc aatgtgtgtg ggctgcagag ctgtgtggct
      241 gcccgcttcc ccagtggcgg cccagctaca cctgagacag cagcctcctg cgaagacttc
      301 caatgcccac aacagggttc caactgtgac atctgggatg ggcagccggt ttgtcgctgc
      361 cgtgaccgct gtgaaaaaga gcccagcttc acttgcgctt ctgatggcct cacctattac
      421 aaccgctgct atatggacgc agaagcctgc ctgcgaggtc tccacctgca tgtcgtaccc
      481 tgtaaacaca ttctcagttg gccacccagc agccccggac cacctgagac cactgctcgc
      541 ccaacccctg gggctgctcc catgccacct gccctataca acagcccctc accacaagcc
      601 gtgcatgtgg ggggaacagc cagcctccac tgtgacgtta gtggccgtcc accacctgcc
      661 gtgacatggg agaagcagag ccatcagcgg gagaacctga tcatgcgccc cgaccaaatg
      721 tacggcaacg tggttgtcac cagcattgga cagctagtgc tctacaatgc tcagctggag
      781 gatgcaggcc tgtacacctg caccgcacgg aatgctgctg gcctgctgcg ggctgacttt
      841 cccctttcgg ttttgcagcg ggcaactact caggacaggg acccaggtgt cctggccctg
      901 gctgagtgcc agcccgacac acaagcctgt gttggcccac ctacccccca tcatgtcctt
      961 tggcgctttg acccgcaacg aggcagctgc atgacattcc cagccctcaa atgcgatggg
     1021 gctgcccggg gctttgagac ctatgaggca tgccaacagg cctgtgtccg tggccctggg
     1081 gatgtctgtg cgctgcctcc agtccagggc ccctgccagg gctgggagcc acgctgggcc
     1141 tacagcccac tgctgcagca gtgccacccc tttatataca gtggctgtga gggaaacagc
     1201 aataactttg agagcaggga gagctgtgag gatgcttgcc ctgtaccacg cacaccaccc
     1261 tgccgtgcct gccgtctcaa gagcaagctg gccctgagct tgtgccgcag tgactttgcc
     1321 attgtgggca gactcacaga agtactggag gaacccgagg ctgcaggcgg cattgctcgt
     1381 gtggccttag atgacgtgct aaaggatgac aagatgggcc tcaagttctt aggcaccaaa
     1441 tacctggagg tgacactaag tggcatggac tgggcctgcc catgccccaa tgtgacagtt
     1501 ggcgatgggc cactggtcat catgggtgag gttcgtgaag gtgtggctgt gttggacgcc
     1561 aacagctacg tccgtgctgc cagtgagaag cgagtcaaga agattgtaga actgcttgag
     1621 aagaaggctt gtgaactgct caaccgcttc caagactag
//
