LOCUS       NM_001107908            4150 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus WD and tetratricopeptide repeats 1 (Wdtc1), mRNA.
ACCESSION   NM_001107908 XM_001064989 XM_008764134 XM_232730
VERSION     NM_001107908.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4150)
  AUTHORS   Suh,J.M., Zeve,D., McKay,R., Seo,J., Salo,Z., Li,R., Wang,M. and
            Graff,J.M.
  TITLE     Adipose is a conserved dosage-sensitive antiobesity gene
  JOURNAL   Cell Metab 6 (3), 195-207 (2007)
   PUBMED   17767906
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On or before Jun 3, 2021 this sequence version replaced
            XM_008764134.3, NM_001107908.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.22979.1,
                                           SRR26643297.20416.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-282               JAXUCZ010000005.1  150824026-150824307 c
            283-429             JAXUCZ010000005.1  150807548-150807694 c
            430-513             JAXUCZ010000005.1  150805930-150806013 c
            514-560             JAXUCZ010000005.1  150797624-150797670 c
            561-672             JAXUCZ010000005.1  150797201-150797312 c
            673-860             JAXUCZ010000005.1  150791843-150792030 c
            861-1043            JAXUCZ010000005.1  150789528-150789710 c
            1044-1138           JAXUCZ010000005.1  150788023-150788117 c
            1139-1254           JAXUCZ010000005.1  150787460-150787575 c
            1255-1327           JAXUCZ010000005.1  150785374-150785446 c
            1328-1436           JAXUCZ010000005.1  150784727-150784835 c
            1437-1610           JAXUCZ010000005.1  150783570-150783743 c
            1611-1846           JAXUCZ010000005.1  150780285-150780520 c
            1847-2021           JAXUCZ010000005.1  150779350-150779524 c
            2022-2214           JAXUCZ010000005.1  150778204-150778396 c
            2215-4150           JAXUCZ010000005.1  150775358-150777293 c
FEATURES             Location/Qualifiers
     source          1..4150
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..4150
                     /gene="Wdtc1"
                     /note="WD and tetratricopeptide repeats 1"
                     /db_xref="GeneID:313020"
                     /db_xref="RGD:1310362"
     exon            1..282
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            283..429
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             382..2412
                     /gene="Wdtc1"
                     /codon_start=1
                     /product="WD and tetratricopeptide repeats protein 1"
                     /protein_id="NP_001101378.1"
                     /db_xref="GeneID:313020"
                     /db_xref="RGD:1310362"
                     /translation="MAKVNITRDLIRRQIKERGALSFERRYHVTDPFIRRLGLEAELQ
                     GHSGCVNCLEWNEKGDLLASGSDDQHTIVWDPLHHKKLLSMHTGHTANIFSVKFLPHA
                     GDRILITGAADSKVHVHDLTVKETIHMFGDHTNRVKRIATAPMWPNTFWSAAEDGLIR
                     QYDLRENSKHSEVLIDLTEYCGPMVEAKCLTVNPQDNNCLAVGASGPFVRLYDIRMIH
                     NHRKSMKQSPSAGVHTFCDRQKPLPDGAAQYYVAGHLPVKLPDYNSRLRVLVATYVTF
                     SPNGTELLVNMGGEQVYLFDLTYKQRPYTFLLPRKCHSVEVQNGKMSTNGVSNGVSNG
                     LHLHSNGFRLPESKGCISPQVELPPYLERVKQQANEAFACQQWTQAIQLYSKAVQKAP
                     HNAMLYGNRAAAYMKRKWDGDHYDALRDCLKAISLNPCHLKAHFRLARCLFELKYVAE
                     ALECLDDFKGKFPEQAHSSACDALGRDITAALFSKSDGEEKKAAGGGGPVRLRSTSRK
                     DSISEDEMVLRERSYDYQFRYCGHCNTTTDIKEANFFGSNAQYIVSGSDDGSFFIWEK
                     ETTNLVRVLQGDESIVNCLQPHPSYCFLATSGIDPVVRLWNPRPESEDLTGRVVEDME
                     GASQANQRRMNANPLEAMLLDMGYRITGLSSGGAGASDDEDSAEGQVQCRPS"
     exon            430..513
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            514..560
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            561..672
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            673..860
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            861..1043
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1044..1138
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1139..1254
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1255..1327
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1328..1436
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1437..1610
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1611..1846
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            1847..2021
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2022..2214
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..4150
                     /gene="Wdtc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ataaacagag gaggagggag gggagtgcgt gtgtgagagc gcgcgaggga gtgtgagtgt
       61 gtgtgagcgc gggtgtgagg cggtgcgcag gggcgggcgg aggcgctgtc cggccccggc
      121 caggcgccgg gcggggagca tgggaagagg ctagagctgc tcgggtcccc agcccccttc
      181 ccgggatccg caaccctgct cccgggagag gggccgggcc ccctggaccg acatgggctc
      241 ctgaagttgc tccgctgctg gtcctgggaa gagacctgac aggtaattaa atgcttgtct
      301 tgtggacctg ggcttggctg gaatgtgcaa gggtcttgaa gatccttcta tagcttcctt
      361 ctgttgaacc attaagagaa gatggcaaaa gtcaatataa ctagagacct cattcgtagg
      421 caaattaagg agcggggtgc cctgagcttt gagcggcgat atcatgtcac tgaccctttt
      481 atccggcggc tgggcctgga agcagagctt cagggtcact cgggatgtgt caactgtctg
      541 gagtggaacg agaaaggaga cttgctggct tctggctccg atgaccagca caccatcgtg
      601 tgggacccac tgcaccacaa gaagctgctc tccatgcaca caggacacac agcaaatatc
      661 ttctctgtca agttcctgcc gcatgccgga gaccgcatcc tgatcacagg ggcagctgac
      721 tccaaggtgc acgtccacga cctgacggtg aaggaaacga tccacatgtt tggagaccat
      781 acaaaccggg tgaagcgcat tgccacggca cccatgtggc ctaacacgtt ctggagcgct
      841 gctgaggacg ggctcatccg ccagtatgac cttcgggaga acagcaaaca ttcagaggtg
      901 ctgattgacc taacagaata ctgtggcccg atggtggagg ccaagtgcct cactgtcaat
      961 ccccaggata acaactgcct ggccgtaggg gccagtgggc cctttgtgag gctctatgac
     1021 attcgaatga tccataacca cagaaagagc atgaagcaga gcccttcggc gggtgtgcac
     1081 accttctgtg accggcagaa gccccttccg gacggtgcag cacagtatta tgtcgcaggt
     1141 cacctgccgg tgaagctgcc tgactataac agccgtctga gagtgctggt cgccacttac
     1201 gtgaccttca gccccaatgg tacagagctg ctggtcaaca tgggaggaga gcaggtgtac
     1261 ttgtttgact tgacttacaa gcaacggccg tataccttcc tcttgcctag aaaatgtcac
     1321 tcagtggaag tccagaatgg caagatgtct actaatggcg tgtctaacgg cgtgtcgaat
     1381 ggtctgcacc ttcacagcaa cggcttccgg ctgccagaaa gcaaggggtg tatcagtccc
     1441 caggtggagc tccccccata cctggagcgc gtgaagcagc aagccaacga agcctttgcc
     1501 tgccagcagt ggacgcaggc catccagctt tacagcaagg ctgtgcagaa ggcccctcac
     1561 aacgccatgc tctacggaaa cagggctgct gcctacatga aacgcaagtg ggatggtgac
     1621 cactacgatg ccctccggga ctgcctcaag gccatctccc taaacccttg ccacctgaag
     1681 gcacacttcc gtctggcccg gtgcctcttt gaactgaagt atgtggccga ggctctggag
     1741 tgcctggatg acttcaaagg gaagttccca gagcaggccc acagcagtgc ttgtgacgca
     1801 ctgggccggg acatcacagc tgcccttttc tccaaaagtg atggcgagga gaagaaggca
     1861 gctggcggtg gtggtccagt tcgcctccga agcacaagcc gcaaggactc catctccgag
     1921 gacgagatgg tgctacggga gcgcagctac gactaccagt tccgctactg tggccactgc
     1981 aacaccacaa cggacatcaa ggaggcaaat ttctttggca gcaatgctca gtacatcgtc
     2041 agcggctctg atgatggctc cttcttcatc tgggaaaagg agaccaccaa cctagtccga
     2101 gtgctccagg gagatgaatc cattgtcaac tgcttgcagc cacaccccag ctactgcttc
     2161 ctggctacca gtggcatcga ccctgtggtg cgattgtgga acccacgacc agagagtgaa
     2221 gacctcacgg gccgagtcgt ggaggacatg gagggtgcct ctcaggccaa ccagcggcgc
     2281 atgaatgcca atcccctgga ggcgatgctg ctggacatgg gctaccggat cacaggcctg
     2341 agcagtgggg gcgctggggc ctccgatgac gaggacagcg cagagggcca ggtgcagtgc
     2401 cggcccagct agatgctcct agccccagtc cccggccctg tgcaggagat cagagggctg
     2461 ggctctgttt tggtttgtct ttcccacccc catttttcat ttcccctgtt ttgtttgtta
     2521 gttcgacatt gtgggtgggg attgctgcaa cttgctggct ttcagactct cgggctgatt
     2581 gtcccttgac tgtccacagc cctgagcaga aaagcaggag gggaagtccc tccatatgcc
     2641 cttacctcct gcttccgtgt ctctggaagg ctctggccct tctcaaaacc ccttccgcct
     2701 ccagtgggga ggcaagagct gaagctgtct tcacggactg ccctgcctct tggttggcaa
     2761 cagaaaggga gtggaactcc ctgctgtcaa aggcttgcct tggcctgttg ttgccacttg
     2821 ctctcctgcc tatggggcta gctcccctga ggtctttctg gaaggtccct tcccagccac
     2881 cagtgctctg gtggaaccgt aggaaaggtg ggagcccgca gtggcaaggt caggcctcct
     2941 gccctggtgg cagtggagct ttctcatccc ctcctgggcc tgttctaggc tggctctgag
     3001 ggctttgcct ttcctctggt gtggcagagg gtggggtgcc tcgtccccac ccacctgccc
     3061 atgcaagtac taatgcgcca tggccgctct cctggggcgc tcctcggcct cactgtgacc
     3121 tttctgccag agctcccagc caggcctcct ctgctgaggt ggcgcttcct aaggaccctt
     3181 ctcgccctct ctgccctcct tcccacccat gtgctgagcc gccacaaaga ccaaagaagt
     3241 gatggctttt ctctgtcccc tgctgctctg gggggagggg gtgggaaagt ccttagctca
     3301 gccatccctt ctcagcagcc ccaagcttta cactggacac agcgcccact ccaccaccaa
     3361 gcctccctct ccctctagcc cctctagccc ctccctctag ccggtgcctg ctctggagct
     3421 gggagttggt tcatgccagc ctcccccagc cctgtgtgct tcctctgggc tgcagccctc
     3481 cagctgcagc ctctggggag aagcagcctc ccttctctcc ctccctccat acctccctcc
     3541 ttcccttcct ctctccctcc ctcgcccctg tctccgccag gtgcctcctc tcagtcaagc
     3601 ttctgagcag ccctggagac aggagggcca tgttaaaagc tttttcacag ttttaagaag
     3661 actagggggg tgaggctagt agtggggggt ctggcaccat ctcattgctt taatctcagc
     3721 gacacaggtg gcagcttctc ccccttcctg cccaccccag gtcctcttcc cacccctctc
     3781 ttctagcttg gtaatgaagt gtatttattg gtgaaggaaa cagctgctgc tgcggctcct
     3841 gctgctggga cttgctcccc tgctcttcct catgaccttt ctcaagccag ggaggggagc
     3901 gggagtgttg ggctagaccc tggggctcga gaactggcca gggtcccttt gctttcctat
     3961 gttgaagcca cctgccattc ccccgtccct gcctcctgtc tcccacccgc ctgcctagcc
     4021 tggaccctgc agtgtggaga gacacataag ccttactgtc ctctgggggc aggagccgag
     4081 cctttttgtt gctctgctcc caggagagtg agggtgacgc aattgattaa aaccattttg
     4141 ttctacttgt
//
