LOCUS       NM_001271306            3802 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus WD repeat domain 82 (Wdr82), mRNA.
ACCESSION   NM_001271306 XM_001073342
VERSION     NM_001271306.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3802)
  AUTHORS   Grolimund,L., Aeby,E., Hamelin,R., Armand,F., Chiappe,D.,
            Moniatte,M. and Lingner,J.
  TITLE     A quantitative telomeric chromatin isolation protocol identifies
            different telomeric states
  JOURNAL   Nat Commun 4, 2848 (2013)
   PUBMED   24270157
REFERENCE   2  (bases 1 to 3802)
  AUTHORS   Vethantham,V., Yang,Y., Bowman,C., Asp,P., Lee,J.H., Skalnik,D.G.
            and Dynlacht,B.D.
  TITLE     Dynamic loss of H2B ubiquitylation without corresponding changes in
            H3K4 trimethylation during myogenic differentiation
  JOURNAL   Mol Cell Biol 32 (6), 1044-1055 (2012)
   PUBMED   22252316
REFERENCE   3  (bases 1 to 3802)
  AUTHORS   Shilatifard,A.
  TITLE     The COMPASS family of histone H3K4 methylases: mechanisms of
            regulation in development and disease pathogenesis
  JOURNAL   Annu Rev Biochem 81, 65-95 (2012)
   PUBMED   22663077
  REMARK    Review article
REFERENCE   4  (bases 1 to 3802)
  AUTHORS   Bi,Y., Lv,Z., Wang,Y., Hai,T., Huo,R., Zhou,Z., Zhou,Q. and Sha,J.
  TITLE     WDR82, a key epigenetics-related factor, plays a crucial role in
            normal early embryonic development in mice
  JOURNAL   Biol Reprod 84 (4), 756-764 (2011)
   PUBMED   21123813
REFERENCE   5  (bases 1 to 3802)
  AUTHORS   Lee,J.H., You,J., Dobrota,E. and Skalnik,D.G.
  TITLE     Identification and characterization of a novel human PP1
            phosphatase complex
  JOURNAL   J Biol Chem 285 (32), 24466-24476 (2010)
   PUBMED   20516061
REFERENCE   6  (bases 1 to 3802)
  AUTHORS   Wu,M., Wang,P.F., Lee,J.S., Martin-Brown,S., Florens,L.,
            Washburn,M. and Shilatifard,A.
  TITLE     Molecular regulation of H3K4 trimethylation by Wdr82, a component
            of human Set1/COMPASS
  JOURNAL   Mol Cell Biol 28 (24), 7337-7344 (2008)
   PUBMED   18838538
REFERENCE   7  (bases 1 to 3802)
  AUTHORS   Lee,J.H. and Skalnik,D.G.
  TITLE     Wdr82 is a C-terminal domain-binding protein that recruits the
            Setd1A Histone H3-Lys4 methyltransferase complex to transcription
            start sites of transcribed human genes
  JOURNAL   Mol Cell Biol 28 (2), 609-618 (2008)
   PUBMED   17998332
REFERENCE   8  (bases 1 to 3802)
  AUTHORS   Lee,J.H., Tate,C.M., You,J.S. and Skalnik,D.G.
  TITLE     Identification and characterization of the human Set1B histone
            H3-Lys4 methyltransferase complex
  JOURNAL   J Biol Chem 282 (18), 13419-13428 (2007)
   PUBMED   17355966
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Sep 13, 2012 this sequence version replaced XM_001073342.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643289.23960.1,
                                           SRR26643429.31910.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-454               JAXUCZ010000008.1  115693297-115693750
            455-552             JAXUCZ010000008.1  115698977-115699074
            553-619             JAXUCZ010000008.1  115702710-115702776
            620-719             JAXUCZ010000008.1  115705713-115705812
            720-836             JAXUCZ010000008.1  115706278-115706394
            837-992             JAXUCZ010000008.1  115706752-115706907
            993-1062            JAXUCZ010000008.1  115707217-115707286
            1063-1205           JAXUCZ010000008.1  115708272-115708414
            1206-3802           JAXUCZ010000008.1  115710666-115713262
FEATURES             Location/Qualifiers
     source          1..3802
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..3802
                     /gene="Wdr82"
                     /note="WD repeat domain 82"
                     /db_xref="GeneID:686295"
                     /db_xref="RGD:1584269"
     exon            1..454
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     CDS             294..1235
                     /gene="Wdr82"
                     /codon_start=1
                     /product="WD repeat-containing protein 82"
                     /protein_id="NP_001258235.1"
                     /db_xref="GeneID:686295"
                     /db_xref="RGD:1584269"
                     /translation="MKLTDSVLRSFRVAKVFRENSDKINCFDFSPNGETVISSSDDDS
                     IVLYDCQEGKPKRTLYSKKYGVDLIRYTHAANTVVYSSNKIDDTIRYLSLHDNKYIRY
                     FPGHSKRVVALSMSPVDDTFISGSLDKTIRLWDLRSPNCQGLMHLQGKPVCSFDPEGL
                     IFAAGVNSEMVKLYDLRSFDKGPFATFKMQYDRTCEWTGLKFSNDGKLILISTNGSFI
                     RLIDAFKGVVMHTFGGYANSKAVTLEASFTPDSQFIMIGSEDGKIHVWNGESGIKVAV
                     LDGKHTGPITCLQFNPKFMTFASACSNMAFWLPTIDD"
     exon            455..552
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            553..619
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            620..719
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            720..836
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            837..992
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1062
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            1063..1205
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
     exon            1206..3802
                     /gene="Wdr82"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gattttgctt ctccctttaa gatggcggac acaatgagcc ggcggagcgc cggttggccc
       61 tgaagtgact ctggagaacg gtcagcgagg tcccgtcatc ccggcaagag agcgttgctt
      121 gaggaagaaa acgccgcagt cccactgtca gccgccttcc cgttcgtctc tagcgcggcg
      181 cccgcaccgc cggggttggc cctgagcagc ccgcccgctc gctcgcctct cggccccgcc
      241 ccggccctgc gccgccgccg ctgccttcag cagcagccgc tgctgccgcc gccatgaagc
      301 tgaccgacag cgtgctgagg agcttccgcg tcgccaaggt gttccgcgag aactcggaca
      361 agatcaactg ctttgacttc agtcccaatg gggagacggt catctccagt agcgatgatg
      421 actccatcgt gctctatgac tgccaggagg gcaaaccaaa gagaaccctg tacagtaaga
      481 aatatggtgt ggacctcatc agatacaccc atgcagcaaa cacagtcgtt tacagctcta
      541 acaaaataga cgatactatt cgttacttgt ccttgcatga caataaatac atcagatact
      601 ttcctggaca cagcaagagg gtggtggcct tgtccatgtc acctgtggat gacactttca
      661 tttctgggtc tcttgataag accattcgac tctgggatct ccggtctcct aactgccagg
      721 gcctcatgca tctacagggc aaacccgttt gttcctttga tccagaaggg ttaatttttg
      781 ctgcaggtgt caactcagaa atggtcaaac tttatgacct tcgttctttt gataagggtc
      841 catttgctac ctttaagatg cagtatgatc ggacttgtga gtggacagga cttaagttca
      901 gcaacgatgg caaactgata ctcatctcca ccaacggcag cttcatccgc ctcattgacg
      961 catttaaggg tgtggtgatg cacacatttg ggggttatgc taatagcaaa gctgttacac
     1021 tcgaagcttc ttttactcca gattcacagt ttattatgat tggttcagaa gatggcaaaa
     1081 tccatgtgtg gaatggggag agcggtataa aggtagctgt actggatggg aagcacaccg
     1141 gccccatcac ctgtttgcag ttcaacccca agtttatgac ctttgccagc gcctgttcca
     1201 acatggcctt ctggttaccc accattgatg actgatcctg acgctgctgg gctatttgta
     1261 cagtgagggc ggccgacagg aaaaagtctg aggtgactga gatgacggtg tttgattgat
     1321 catttgactg ggcctggaga acatcttccc acgtggcctt cccagggatg tgctgtccat
     1381 ctgctctaaa ggattacttt gctgagcgcc ttcaggagga cccttggtgc tgcagcttca
     1441 gctggcaccc agccttccag ctctcactgc accaaactct tcagagtgtg actagactta
     1501 cgatcaggac acagaggggc gcctgaaccc cttcagttgt gaatgtactt actgctgagg
     1561 agccagtgaa gtcaccactc cccgcacatc cttctcaccc cagaaatgca tgggaagccg
     1621 tggttctggt tttgagatgt tagggcagct cagcacccct tgccctcacc ctgcatgtct
     1681 tgttactggg tctccctgtg taattaattg tggcattact ccacaaccat catgtttctt
     1741 aggtgccaaa catttacaaa aataagtctt catatacctt ggggtcaaag aaaggacaag
     1801 tacagaggac cgtgtctgtc aggaggctag tcagtattcc tgcacaggtg ggtggggcag
     1861 accttgggct tagatgctgg gtgacaaagg cccaagagtc tgacagggag ggaggggtag
     1921 caggtaaatt ctgagagctg aaaggtttag cagcctggtg cacttccccc atcaagacaa
     1981 tcccacagtc tctcttgtgg gggatcctac cgagcttggc ttgtacaaaa gcaaggtagt
     2041 agtttatttt tgtacctgag tcacatcacg ttttcctgtg ggccagtatt gtggaatgag
     2101 tctgagttgt ttacactgat gccttccttc cctgcccacc acaaatcgtg tacatagtca
     2161 gcagatgaaa cccctcttct ccagctccta cccgagagct ggctctaggc ctgtgttata
     2221 tgttctattt agctttttat atatgaccct tgatctgtgt atttgaacac tgtgtgtgtc
     2281 cacttacctt tgtgcagacg tgcacattgc gtatgtgtat atgcctgtct catctagctt
     2341 atcaagagtt cggcaggaga gggaagcctg cggccgagaa tgactctttg tggatagtgt
     2401 atgccacaat cgttagtctt ctccgttaac cttagggata caacgtgaag cagagcttct
     2461 agtgtttgct gtttcatggc agctaagtgg gggccttggg tgactccctt gtgctctcta
     2521 agccacacca cggggccctc tctacagtgt tagaatcttt tgcctgatta tgctctgtct
     2581 gcacctgtat atgtgtggca gtcacttttg catggcttct gtgcctggct tgtggcattt
     2641 agggacaggg tgctggaacc acagtgtttt tagtttgtca gaacttaatt ggccaacaat
     2701 aagtcactgt cacctgctgt gtctacactg ttgccctttt tcttgctttt tcctgagaga
     2761 cttttagcta gacccagact agatgagttg cagttgacct ttccttccca gcatggcagc
     2821 cttagagtag gacaaatggc tgtcaaatac tgatgcagcg atatccctgc acatccagaa
     2881 atcaagaccc agcaggctgt gatttgccca agagtaccca gctgtagcgg gtggcaggca
     2941 ggccgtcact gcttctgtgc agcagcagac agtcttccag tcaccaacgc tactttttaa
     3001 gcaattactt tttgacttgt tattccaact gaaagaagtt ggactgatac tgaagtctgt
     3061 aagcactgct gaacactcct gctataaatg tctgccttcc cggagcagac cactgtagga
     3121 accaggcgac cggagctgtt actgcctacc ttcagggttt aaaagcccat gtccaaaaga
     3181 cccattgagg gcaaatgtct aactgtaggt gaatatggct gcatggcctg aaagtaagag
     3241 tggcttgcct gaccgcagga agtcgtctga gtgtccagag ttgaggcatc atgcttttgg
     3301 aaggcatact tcctgcccac agcctctgct gggccctgtg gccacagagc tgagttctga
     3361 attggtagga aaaggtgcaa ctggaattta catggtcaca gggtaagaaa gagggaaagc
     3421 agagatggca gtttggggta tgttcctggg acgtattcac tgtcctctga aagatcagcc
     3481 agagccgctg ctctgtatgt gacagctgac actgcactgt tcaaccacca gccactgggg
     3541 tattttttaa taaattattc cctgttgtaa ttgacaatta ctgcttatga aggaaaattg
     3601 ggagatcttt aagaaccagt ttgctaccca atggtaccac tgttaatctt gatgttaaat
     3661 gttcctttag atatctctgt gcataaactt tggtgtttac atagttgtta ttctactgta
     3721 catacaattt tgtccttttt gtacttaaca tataaacttt tttttgccat gttaccagtc
     3781 ttaaacagaa ttttataatt ta
//
