LOCUS       NM_001399180            2631 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus WD repeat domain 75 (Wdr75), mRNA.
ACCESSION   NM_001399180 XM_006244892
VERSION     NM_001399180.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2631)
  AUTHORS   Ivatt,R.M., Sanchez-Martinez,A., Godena,V.K., Brown,S., Ziviani,E.
            and Whitworth,A.J.
  TITLE     Genome-wide RNAi screen identifies the Parkinson disease GWAS risk
            locus SREBF1 as a regulator of mitophagy
  JOURNAL   Proc Natl Acad Sci U S A 111 (23), 8494-8499 (2014)
   PUBMED   24912190
REFERENCE   2  (bases 1 to 2631)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   3  (bases 1 to 2631)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   4  (bases 1 to 2631)
  AUTHORS   Prieto,J.L. and McStay,B.
  TITLE     Recruitment of factors linking transcription and processing of
            pre-rRNA to NOR chromatin is UBF-dependent and occurs independent
            of transcription in human cells
  JOURNAL   Genes Dev 21 (16), 2041-2054 (2007)
   PUBMED   17699751
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000009.1.
            
            On Jan 4, 2022 this sequence version replaced XM_006244892.4.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643286.28161.1,
                                           SRR26643429.33618.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               JAXUCZ010000009.1  55395232-55395335
            105-234             JAXUCZ010000009.1  55398915-55399044
            235-300             JAXUCZ010000009.1  55400581-55400646
            301-391             JAXUCZ010000009.1  55401488-55401578
            392-516             JAXUCZ010000009.1  55403468-55403592
            517-587             JAXUCZ010000009.1  55404952-55405022
            588-707             JAXUCZ010000009.1  55406265-55406384
            708-796             JAXUCZ010000009.1  55407334-55407422
            797-955             JAXUCZ010000009.1  55412474-55412632
            956-1015            JAXUCZ010000009.1  55413522-55413581
            1016-1131           JAXUCZ010000009.1  55413672-55413787
            1132-1307           JAXUCZ010000009.1  55414957-55415132
            1308-1465           JAXUCZ010000009.1  55416847-55417004
            1466-1646           JAXUCZ010000009.1  55417454-55417634
            1647-1741           JAXUCZ010000009.1  55420114-55420208
            1742-1837           JAXUCZ010000009.1  55420864-55420959
            1838-2007           JAXUCZ010000009.1  55421525-55421694
            2008-2067           JAXUCZ010000009.1  55422175-55422234
            2068-2214           JAXUCZ010000009.1  55424260-55424406
            2215-2306           JAXUCZ010000009.1  55424698-55424789
            2307-2631           JAXUCZ010000009.1  55425088-55425412
FEATURES             Location/Qualifiers
     source          1..2631
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q22"
     gene            1..2631
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /note="WD repeat domain 75"
                     /db_xref="GeneID:314545"
                     /db_xref="RGD:1564869"
     exon            1..104
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     CDS             22..2511
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /codon_start=1
                     /product="WD repeat-containing protein 75"
                     /protein_id="NP_001386109.1"
                     /db_xref="GeneID:314545"
                     /db_xref="RGD:1564869"
                     /translation="MVEERVRVVRCGGSRLNFRRAVFSVDSKYIFCVSGDFIKVYSTA
                     TEECVHILRGHKHVVSGILINPNNHLQLYSCSFDGTIKLWDYLDGILIKTFTVGPKLH
                     ALFIPAHAEDTVFLTINKEDPDIFQLVSVKLPKSTSRNVEAKELTFVLDYINKSPKSI
                     AFGNEGEYVAAVRDFYLSVYFLKKKKTCNFTLPSTKNKKNARNKFTCVACHPKEDCIA
                     SGHMDGKIRLWRNFHDDKLYTYTCLHWHHDMVMDLAFTVTGTSLLSGGQECVLVEWRD
                     GSEKNKEFLPRLGSAIEHISVSPAGDLFCTSHSDNKITVIHRNLDASAVIQGLVKDRS
                     ISTGLMVDPRTKALVLNGKPGHLQFYSLQSDKQLYNLDIIQQEYINDQGLIQIELTKA
                     AFGCSGSWLATVEQRQENENELELQMKLWNYSKKTQGFVLNTKISMPHDDHITALCFN
                     NAENYEKPILVTASRDGHFKVWVLTDDSDIYKKAIGWTCDFVGSYHKYQATNCCFSED
                     GSLLAVSFEEIVTIWDSETWELKCTFCQRAGKIRHLCFGRLTCSKYLLGTTENNLLCC
                     WNLLSCSMQWSAKLNVRVMEADPYSDHIAAVARSSEGSDLFVFKPSEPRPLYIQKNVS
                     REKVQWGVFVPRDVPESFTSEAHQWLNRSQFYFLTESQCLLTFSTKYAEEKLTPTSKQ
                     LLAEESLPTTPFSFILGKHRQQQDTKSTETSESELVQLPLTENIPAITELLHTPAHVL
                     PSASFLCTLFVNSLLLSKETKSAEEISDDVDMEGNEESDDSDEEYDLTEKAKETSNPD
                     LGEDAIHQLSKSEEKELRKFRKVDYSWLTAL"
     exon            105..234
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            235..300
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            301..391
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            392..516
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            517..587
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            588..707
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            708..796
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            797..955
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            956..1015
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1016..1131
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1132..1307
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1308..1465
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1466..1646
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1647..1741
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1837
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            1838..2007
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            2008..2067
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            2068..2214
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            2215..2306
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
     exon            2307..2631
                     /gene="Wdr75"
                     /gene_synonym="LRRG00118"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggttcctgcg tctgcgggaa gatggtagag gagagagtcc gcgtggttcg ctgcggcggc
       61 agccggctga acttcaggag agctgtgttc tctgtggatt ccaagtatat cttctgtgtc
      121 tcgggagact ttattaaggt ctacagcaca gccacagaag agtgtgtaca cattctgcgt
      181 gggcacaaac atgtggtgtc tggaatcctc atcaacccca acaaccacct tcagctctac
      241 tcttgttcct tcgatggcac aattaagctg tgggactatc ttgatggcat tttgataaag
      301 actttcactg ttggacctaa actccatgcc ctctttattc ctgcccacgc cgaagatact
      361 gtcttcctta caataaataa agaagatcca gacatatttc agctggtgtc agtgaaactg
      421 cccaagtcga caagccggaa cgtggaagct aaggagctta cctttgttct ggattacata
      481 aacaagtccc ccaagagcat tgccttcgga aatgagggag aatatgttgc tgcagtccgg
      541 gacttttact tatctgttta ttttctcaaa aagaaaaaaa catgcaattt tactttacca
      601 tcaacaaaaa acaagaagaa tgcaaggaac aagttcacat gtgtagcctg ccatccaaag
      661 gaagattgca tcgcatctgg ccacatggac ggcaaaatcc gcctctggag gaattttcat
      721 gatgataagc tatacacata cacatgttta cattggcacc atgacatggt tatggatttg
      781 gcttttacag taacaggcac cagtctgctg agtggtgggc aggagtgtgt gcttgtggag
      841 tggagagacg ggtcagagaa gaacaaagag ttccttccgc gattaggatc tgctattgag
      901 cacatctctg tctcacccgc gggagatttg ttctgcacgt ctcactctga caacaagata
      961 acagttattc accgaaatct tgatgcgtct gcagtgattc aaggcctagt gaaagatagg
     1021 agtatatcca ctggtttgat ggttgaccca agaaccaaag ctttagtttt gaatggaaag
     1081 cctggtcacc tgcagtttta ttctctccag agtgataagc agttatataa tctagatatc
     1141 atacagcaag agtacatcaa tgaccagggt ctaatccaaa ttgaactaac gaaggctgcc
     1201 tttggctgct ctggttcttg gttggcaaca gttgaacaac ggcaagaaaa tgaaaatgag
     1261 cttgagctgc aaatgaaact gtggaactac agcaagaaga cccaagggtt tgttcttaac
     1321 acaaagatct ctatgccaca tgatgaccac atcacagctc tctgtttcaa taatgcagaa
     1381 aactatgaaa aacccatact ggtcacagct agcagagatg gccatttcaa agtgtgggta
     1441 ttaacagatg actctgatat atacaaaaaa gccattggct ggacttgtga ctttgtgggt
     1501 agttaccata agtatcaagc aaccaattgt tgtttctctg aagatggctc cttactagca
     1561 gttagtttcg aggaaatagt tacaatatgg gattcagaaa catgggaact aaaatgtaca
     1621 ttctgccaac gagctgggaa aattaggcac ctttgctttg gaagactgac gtgctcaaag
     1681 tatcttctcg gcaccactga gaataacctc ctctgctgtt ggaatctgct cagctgttca
     1741 atgcagtgga gtgcgaaact gaatgtcaga gttatggaag ccgaccctta ctcggaccac
     1801 atcgccgcag tggctcggtc ttcagaaggc tcagatctgt ttgtatttaa acctagcgag
     1861 ccaaggccac tgtatattca aaagaatgtc tccagagaga aagtccagtg gggagtgttt
     1921 gttccacgag atgtcccaga atcattcacc tcagaagctc accagtggct aaatagatcc
     1981 cagttttact tcctaactga atcacagtgc ttattaacat tcagtacaaa gtatgctgaa
     2041 gagaaactca caccaacaag caaacagctg ctggcagaag aaagtttgcc aacgacccca
     2101 ttttctttta tattgggaaa acacaggcaa cagcaggata caaagtcaac tgaaacttca
     2161 gagagtgaac tggtacaact tcccttaaca gagaacatac ctgcaattac tgagcttctt
     2221 cacaccccag ctcacgtact gccatcagct tcttttctgt gcactctgtt tgtaaactca
     2281 ctgctgctgt ctaaagagac taaaagtgct gaagaaattt ctgatgatgt ggatatggag
     2341 gggaacgaag aaagtgatga ttcagatgaa gaatatgatc ttactgaaaa agccaaggaa
     2401 acaagtaacc cagacttggg agaagatgct atacatcagc tgtcaaagtc tgaagagaaa
     2461 gagctgagaa agttcagaaa agtagattat agctggctaa ctgctctgta ggccatggct
     2521 gtggcatgac atggagatgt gttgtactta atttttactg tctgttaata ctccacaaat
     2581 tttgtaaagt tattttattc ttaagataaa atattaaaag tcttttgttt a
//
