LOCUS       NM_001100702            4102 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus WD repeat domain 47 (Wdr47), mRNA.
ACCESSION   NM_001100702 XM_001071369 XM_001081957
VERSION     NM_001100702.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4102)
  AUTHORS   Buijs RR, Hummel JJA, Burute M, Pan X, Cao Y, Stucchi R, Altelaar
            M, Akhmanova A, Kapitein LC and Hoogenraad CC.
  TITLE     WDR47 protects neuronal microtubule minus ends from
            katanin-mediated severing
  JOURNAL   Cell Rep 36 (2), 109371 (2021)
   PUBMED   34260930
  REMARK    GeneRIF: WDR47 protects neuronal microtubule minus ends from
            katanin-mediated severing.
REFERENCE   2  (bases 1 to 4102)
  AUTHORS   Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M,
            McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel
            JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y,
            Collins SC, Friant S, Godin JD and Yalcin B.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     WD40-repeat 47, a microtubule-associated protein, is essential for
            brain development and autophagy
  JOURNAL   Proc Natl Acad Sci U S A 114 (44), E9308-E9317 (2017)
   PUBMED   29078390
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473952.1.
            
            On or before Nov 30, 2008 this sequence version replaced
            XM_001071369.1, XM_001081957.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMD00132261,
                              SAMD00132262 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..4102
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..4102
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /note="WD repeat domain 47"
                     /db_xref="GeneID:310785"
                     /db_xref="RGD:1309181"
     exon            1..201
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            202..368
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     CDS             211..2976
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /codon_start=1
                     /product="WD repeat-containing protein 47"
                     /protein_id="NP_001094172.1"
                     /db_xref="GeneID:310785"
                     /db_xref="RGD:1309181"
                     /translation="MTAEETVNVKEVEIIKLILDFLNSKKLHISMLALEKESGVINGL
                     FSDDMLFLRQLILDGQWDEVLQFIQPLECMEKFDKKRFRYIILKQKFLEALCVNNAMS
                     AEDEPQHLEFTMQEAVQCLHALEEYCPSKDDYSKLCLLLTLPRLTNHAEFKDWNPSTA
                     RVHCFEEVCVMVAEFIPADRKLSEAGFKASNNRLFQLVMKGLLYECCVEFCQSKATGE
                     EITESEVLLGIDLLCGNGCDDLDLSLLSWLQNLPSSVFSCAFEQKMLNIHVDKLLKPT
                     KAAYADLLTPLISKLSPYPSSPMRRPQSADAYMTRSLNPALDGLTCGLTSHDKRISDL
                     GNKTSPMSHSFANFHYPGVQNLSRSLLLENTECHSIYEESPERSDTPVETQQPVSIEP
                     MCQGSGLEKEPANGAQNPVPAKQQEKNELRDSTEQFQEYYRQRLRYQQHLEQKEQQRQ
                     IYQQMLLEGGVNQEDGPDQQQNLTEQFLNRSIQKLGELNIGMDSLGNEVPVLNQQCLG
                     SKNSGSNNSSVTSFSSPPQDSSQRLTHDTSNIHTSTPRNPGSTNHIPFLEESPCGSQN
                     SSEHSVVKPSPGDSSGSLSRSKGEEDDKSKKQFVCINTLEDTQAVRAVAFHPSGSLYA
                     VGSNSKTLRVCAYPEKLDTSAHDGPKQPVVRFKRNKHHKGSIYCVAWSPCGQLLATGS
                     NDKYVKVLPFNAETCNATGPDLEFSMHDGTIRDLAFMEGPESGGAILISAGAGDCNIY
                     TTDCQRGQGLHALSGHTGHILALYTWSGWMIASGSQDKTVRFWDLRVPSCVRVVGTTF
                     HGTGSAVASVAVDPSGRLLATGQEDSSCMLYDIRGGRMVQSYHPHSSDVRSVRFSPGA
                     HYLLTGSYDMKIKVTDLQGDLTKQLPLMVVGEHKDKVIQCRWHTQDLSFLSSSADRTV
                     TLWTYSG"
     exon            369..452
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            453..537
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            538..1340
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            1341..1470
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            1471..1649
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            1650..1907
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            1908..1983
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            1984..2141
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            2142..2311
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            2312..2482
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            2483..2614
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            2615..2833
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
     exon            2834..4102
                     /gene="Wdr47"
                     /gene_synonym="RGD1309181"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagcggtcgg aggcgggata ggggcggacg cgagaaggac cggctgacga gctgatggat
       61 tgacgtgcgg gctgctgagc ccagaccgcc gccctcgcgc tcgcgcctta gcctggaatt
      121 ggctgccttg gggccctggc cgccggcctc tccgccgcgt tttcctccgc cgcttctgcc
      181 ggctccgccc ggagccctca ggctagcaat atgactgctg aagaaaccgt gaatgtaaaa
      241 gaagttgaga tcattaagct gattttggac ttcttgaatt caaagaagct tcacattagt
      301 atgctggcgc ttgagaagga aagcggagtc ataaatggtc tattttcaga tgatatgctt
      361 ttcctgaggc agcttattct ggatggtcaa tgggatgaag ttcttcagtt cattcagcct
      421 ctagaatgta tggaaaaatt tgacaaaaaa aggtttcgtt atataatcct gaagcagaag
      481 tttctagaag ctttgtgtgt taacaatgca atgtctgcag aagatgagcc ccagcatttg
      541 gaatttacca tgcaggaagc tgtccagtgt ctacacgctc tcgaggagta ctgcccttct
      601 aaagacgatt acagcaagct ctgcctgctc ctcaccctgc ctcgtctgac caaccatgct
      661 gaatttaagg actggaatcc cagcactgcc cgggtccact gctttgaaga ggtctgtgtc
      721 atggtcgcag agttcatccc tgctgacagg aagctaagcg aggctggttt taaagcaagt
      781 aacaaccgct tattccagct cgtaatgaag ggcctacttt atgaatgctg cgtagaattt
      841 tgtcagagta aagcaactgg tgaagaaatt acagaaagtg aagtccttct cggcatcgac
      901 ctcttatgtg gcaacggttg tgatgattta gatctaagtt tattgtcttg gcttcagaat
      961 ctcccttcct ctgtcttttc ttgtgcattt gaacagaaaa tgcttaatat tcatgttgac
     1021 aagctcctga agcctactaa ggctgcatat gctgatctgc tgactcctct tatcagcaaa
     1081 ctgtctccct acccttcatc tccaatgaga agacctcagt cagctgatgc ctatatgact
     1141 cgctctctca atcctgcttt ggatggcctc acatgtggat taaccagtca tgataagagg
     1201 atctcagatc ttgggaacaa aacttctcca atgtcacact cctttgctaa cttccattac
     1261 ccaggggtac agaacctcag cagaagtctt ctgcttgaga atacagagtg tcatagtatc
     1321 tatgaagaat ctcctgagcg aagtgatacc cctgttgaga cccagcagcc tgtgagcatt
     1381 gaacccatgt gccagggttc ggggttagag aaagagcctg caaatggagc acagaaccca
     1441 gttccagcta aacaacaaga aaaaaacgag cttcgagatt ctactgaaca atttcaagaa
     1501 tattataggc aaagattgcg ctatcagcag catctcgaac agaaggagca acagcggcag
     1561 atataccagc agatgttact tgaaggaggt gtgaaccaag aggacggtcc tgatcagcag
     1621 cagaatctta ctgagcaatt ccttaatagg tctattcaaa agcttggcga actaaatatt
     1681 ggaatggaca gtcttggcaa tgaggtgcca gtactcaacc aacaatgcct cgggagcaaa
     1741 aacagtgggt caaataattc ctctgtcact agtttcagtt caccacccca agattccagt
     1801 cagaggttaa cacatgatac ttctaatatt cacacaagta ctcctcgtaa tcctggatca
     1861 acaaatcaca tccctttcct tgaagaatca ccttgtggaa gccagaactc atcagaacat
     1921 tctgttgtta agccatcacc tggagattca tcagggagtc tatcaaggtc aaaaggggaa
     1981 gaggatgaca agtcaaagaa gcagtttgtt tgtattaata ctctagaaga cacacaggct
     2041 gttagagcag tggcgtttca cccaagtggt agtttatatg ccgttggttc aaattcaaaa
     2101 actctgagag tgtgtgccta tccagaaaaa ttggacacaa gtgcacatga cggtcctaag
     2161 cagccagtgg tacgatttaa aagaaacaaa catcataaag ggtctattta ttgtgtggct
     2221 tggagcccgt gtggacagtt actagcaaca ggatcaaacg acaaatatgt gaaagtgctg
     2281 cccttcaatg cagagacttg taatgcaaca ggaccagacc tggaatttag catgcatgat
     2341 gggacaattc gagatctggc ctttatggaa ggcccagaaa gtggtggagc tattttaata
     2401 agtgctggag caggagattg caacatttat acaacagact gtcagagagg acagggtctt
     2461 catgctttga gtggacacac tgggcatatt ttagcacttt atacctggag tggatggatg
     2521 attgcatctg gttcccagga taagactgtt agattctggg atcttcgtgt accaagctgt
     2581 gttcgtgtgg ttggcacaac atttcacgga actggcagtg cagtggcatc tgtggctgtg
     2641 gatcccagtg gccgtctctt agctacaggt caggaggact ccagttgcat gctgtatgac
     2701 ataagaggag gcagaatggt ccagagttac caccctcact ccagtgacgt tcgctctgtt
     2761 cggttctctc ctggagctca ctatttgctg acgggctctt atgacatgaa gataaaggtg
     2821 acagacctgc aaggagacct caccaagcag cttcctctca tggtggtggg ggagcacaag
     2881 gacaaggtga ttcagtgcag atggcacacc caggatcttt ccttcctttc gtcctctgca
     2941 gacagaactg tgaccctctg gacttacagt ggctagaggc catcctgcat tgtctatgca
     3001 gtgaaagcac agagactcga gactactgaa ctgttaggat tacaggcttg aagaacgtat
     3061 actgccccgg agagagttta acccgaggaa gccccttatt accatgtcct atgaacagaa
     3121 ggtgttgggt ggtggttttc agtcttccat gtgtgctcat gctgctgtgt tgtttccttg
     3181 ccaaagtctg cagaagagct cttacgttgt tggtgtgcac gccaagtcat ggttcaggat
     3241 gggtttgtgg tttattatta agtgcactcc ttgggtgtta acccagataa cagttttata
     3301 ctcacactga aatggaatta taatttaagt aattgttaca cataagagaa ccagattttc
     3361 ccccagatga gacataggta ttcaggaatg actttgctct tgtcacaatc catactgtat
     3421 cacgtgtctt ctagtcgtca gggtttggta agtctccaat tttacatgat catctttgca
     3481 tagggctcac cacagagtct ccaggtgaaa ggagaactgc tttctcttaa cccaggggtg
     3541 cacttgctaa tttgtcacat cattttgttt caggctaaaa ggtaataact attttgcttt
     3601 gagaacttgt tgacttcaat tttttgaatg cacaagatac ctcccttcca aactgtagaa
     3661 gcagagcggc agcagttaca tggaaccata ttccatggta gggttaactt accgggtaac
     3721 attttcctct taaaaattaa agactttgcc atgaccctag catggcttga aaagctatgt
     3781 ttgcatgata atttaaaatg gaaaactgaa actttgcact ccataagctt atttgggttt
     3841 ttcttgcaca gttttgtgta atgaggaata atgattttat ttgtacagta ctatatatcc
     3901 taacatttta tgtatcttta ttttcatatt gttcagtatt ttactttaag ttattaaata
     3961 ggctacttta tttatttcag ctgcagtggt attgactgtc tgtgcactat atgtagcaag
     4021 cattttaaat ctatagtaca caagtgggag ggtagaagtg taactgtgct ttttatttca
     4081 ataaagacat cttgacaccc aa
//
