LOCUS       NM_001399044            1905 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus WD repeat domain 4 (Wdr4), mRNA.
ACCESSION   NM_001399044 XM_008772828
VERSION     NM_001399044.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Hu,Y.H., Warnatz,H.J., Vanhecke,D., Wagner,F., Fiebitz,A.,
            Thamm,S., Kahlem,P., Lehrach,H., Yaspo,M.L. and Janitz,M.
  TITLE     Cell array-based intracellular localization screening reveals novel
            functional features of human chromosome 21 proteins
  JOURNAL   BMC Genomics 7, 155 (2006)
   PUBMED   16780588
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1905)
  AUTHORS   Cartlidge,R.A., Knebel,A., Peggie,M., Alexandrov,A., Phizicky,E.M.
            and Cohen,P.
  TITLE     The tRNA methylase METTL1 is phosphorylated and inactivated by PKB
            and RSK in vitro and in cells
  JOURNAL   EMBO J 24 (9), 1696-1705 (2005)
   PUBMED   15861136
REFERENCE   3  (bases 1 to 1905)
  AUTHORS   Alexandrov,A., Martzen,M.R. and Phizicky,E.M.
  TITLE     Two proteins that form a complex are required for 7-methylguanosine
            modification of yeast tRNA
  JOURNAL   RNA 8 (10), 1253-1266 (2002)
   PUBMED   12403464
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000020.1.
            
            On Dec 30, 2021 this sequence version replaced XM_008772828.3.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.57308.1,
                                           SRR26643286.46617.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000020.1  9604591-9604718     c
            129-197             JAXUCZ010000020.1  9602834-9602902     c
            198-341             JAXUCZ010000020.1  9602075-9602218     c
            342-498             JAXUCZ010000020.1  9595955-9596111     c
            499-611             JAXUCZ010000020.1  9595250-9595362     c
            612-672             JAXUCZ010000020.1  9593363-9593423     c
            673-771             JAXUCZ010000020.1  9592764-9592862     c
            772-836             JAXUCZ010000020.1  9591990-9592054     c
            837-1020            JAXUCZ010000020.1  9591244-9591427     c
            1021-1090           JAXUCZ010000020.1  9590712-9590781     c
            1091-1905           JAXUCZ010000020.1  9588532-9589346     c
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..1905
                     /gene="Wdr4"
                     /note="WD repeat domain 4"
                     /db_xref="GeneID:690032"
                     /db_xref="RGD:1585179"
     exon            1..128
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     CDS             40..1278
                     /gene="Wdr4"
                     /codon_start=1
                     /product="tRNA (guanine-N(7)-)-methyltransferase
                     non-catalytic subunit WDR4"
                     /protein_id="NP_001385973.1"
                     /db_xref="GeneID:690032"
                     /db_xref="RGD:1585179"
                     /translation="MASSAGLALCAQTLVVRGGSRFLAFSTASSDDDCLFSYDCSTAE
                     KKSVQEDKGEDGQPADRGSDTILASTFSKSGRYFALTDDSKRLILFRTKPWQCLSVRT
                     VVRRCTALTFTASEDRVLVADKSGDVYSFPVLDSGGCGRLELGHLSMLLDVAVSPDDQ
                     FVLTADRDEKIRVSWAAAPHSIEAFCLGHTEFVSRIFVVPSHPELLLSSSGDGTLRLW
                     KYRSGCQLQCCDLASLQEPGEHSVHKGLAASRIAFWGRESYVVLLCECVPVGFVFQLD
                     ASRQQLVFRQRLTFPHRVWDVVFEETRGLWVLQDCRDAPLALWRPMGSEWQAAPDDAV
                     SQRLCSHLRESWAMLEGSAGADDGFRSLYKATFDNMTSYLKKKEERLKQQLKKKRQRS
                     PHPGSPEQTKKACPARAVSP"
     exon            129..197
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            198..341
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            342..498
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            499..611
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            612..672
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            673..771
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            772..836
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            837..1020
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1021..1090
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1091..1905
                     /gene="Wdr4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctgagcgtc gcacgtgtgc ggaggcggcg gacgggccca tggcgagctc tgcgggcctg
       61 gcactgtgcg cccagacgct ggtggtgcga ggaggcagcc ggttcctagc cttctccacc
      121 gcgagcagcg acgatgactg cctcttctcg tatgactgca gcactgccga gaagaagtcc
      181 gtgcaggaag ataaagggga ggacggacag cccgcagaca gggggagtga cacgattctg
      241 gcgtccacct tctccaagtc tggccgctat tttgctttaa ctgatgacag taagcgtctg
      301 attcttttcc gtacaaaacc atggcaatgt ctgagtgtca ggacggtggt gcggaggtgc
      361 accgccctga ccttcacagc ctccgaggat cgagtcttgg tggctgacaa gtctggagac
      421 gtctactcct tcccggtgct ggattcgggt ggatgtggca ggctggaact tgggcacctc
      481 tccatgctgc tagatgtggc tgtgagtcct gatgaccagt ttgtgctcac cgcagaccgg
      541 gatgagaaga tccgggtcag ctgggctgcc gccccacaca gcatcgaggc tttctgcctg
      601 ggccacacgg agtttgtgag ccgcatcttt gtggtgccca gtcatcctga gctgctgctt
      661 tcttcctccg gggacggcac cctgagactc tggaagtaca gaagtggttg ccagctgcag
      721 tgctgtgacc tggccagcct acaggagcct ggcgagcatt cagtccacaa ggggttggct
      781 gcatccagga ttgcattctg gggacgggag agctatgtgg tgcttctgtg tgagtgtgtc
      841 cctgtgggct tcgtcttcca acttgatgcc agcagacagc agctggtgtt cagacagcgg
      901 ctgactttcc ctcaccgggt gtgggatgtt gtatttgagg agactcgggg cctgtgggtt
      961 ctgcaggact gccgtgatgc ccctctggcg ctctggaggc ccatgggcag cgagtggcag
     1021 gctgctcctg acgatgctgt gtcccagaga ctctgcagcc atctccgtga gagctgggcc
     1081 atgctggaag gctctgctgg tgcagatgat ggcttccgca gcctgtacaa ggccaccttt
     1141 gacaacatga cctcttatct gaagaaaaag gaagagaggc tgaagcagca gctgaagaag
     1201 aagcggcaaa ggagccccca cccagggtcc ccagaacaga ccaaaaaggc gtgcccagcc
     1261 agggcagtca gcccttagct gctgacctcg gcttggtcat ctcatccctg gggccgcacg
     1321 gccagctctc ctctcccttc tgtctggctt atccctcagg gagatcgtgg cagctccgtc
     1381 cccaccacga gctcagcagc ctctggtctc tagagactgc ctctgccact gagcacagtc
     1441 tcctgcccag cggcagggag acagaccgtg ttagctaatg agtctctatt agctgtgtgg
     1501 aagcaccttc acattgaagg atacgctgac cacagcacca cgcacgactg tcagtgccta
     1561 gagtggtgcc ctggggatct ctagggaggt ctggagtagg caggacctgc catcacaggg
     1621 tgccttcgct cccttggggt tggagccctg aatcactcac gtagctgctt gctgttgtga
     1681 ggcagatggt actgtttctc tgtagcctca gtctggggct gagcagacca agcaggcttc
     1741 agggctgtga gggtgtggcc ttgccgggcc agccttgttt acagggaatg actggtgacc
     1801 tcatgggtct gctgctttga cctctgcatg cgctgcagaa cagaagtgag tgaagagaat
     1861 acacagcatc aataaagaca gctttgcata gctttctgga atgtt
//
