LOCUS       NM_001400815            3142 bp    mRNA    linear   ROD 09-APR-2024
DEFINITION  Rattus norvegicus WD repeat domain 36 (Wdr36), mRNA.
ACCESSION   NM_001400815 XM_039097400
VERSION     NM_001400815.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3142)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   2  (bases 1 to 3142)
  AUTHORS   Mookherjee,S., Chakraborty,S., Vishal,M., Banerjee,D., Sen,A. and
            Ray,K.
  TITLE     WDR36 variants in East Indian primary open-angle glaucoma patients
  JOURNAL   Mol Vis 17, 2618-2627 (2011)
   PUBMED   22025897
REFERENCE   3  (bases 1 to 3142)
  AUTHORS   Chi,Z.L., Yasumoto,F., Sergeev,Y., Minami,M., Obazawa,M.,
            Kimura,I., Takada,Y. and Iwata,T.
  TITLE     Mutant WDR36 directly affects axon growth of retinal ganglion cells
            leading to progressive retinal degeneration in mice
  JOURNAL   Hum Mol Genet 19 (19), 3806-3815 (2010)
   PUBMED   20631153
REFERENCE   4  (bases 1 to 3142)
  AUTHORS   Fan,B.J., Wang,D.Y., Cheng,C.Y., Ko,W.C., Lam,S.C. and Pang,C.P.
  TITLE     Different WDR36 mutation pattern in Chinese patients with primary
            open-angle glaucoma
  JOURNAL   Mol Vis 15, 646-653 (2009)
   PUBMED   19347049
REFERENCE   5  (bases 1 to 3142)
  AUTHORS   Miyazawa,A., Fuse,N., Mengkegale,M., Ryu,M., Seimiya,M., Wada,Y.
            and Nishida,K.
  TITLE     Association between primary open-angle glaucoma and WDR36 DNA
            sequence variants in Japanese
  JOURNAL   Mol Vis 13, 1912-1919 (2007)
   PUBMED   17960130
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 3142)
  AUTHORS   Hewitt,A.W., Dimasi,D.P., Mackey,D.A. and Craig,J.E.
  TITLE     A Glaucoma Case-control Study of the WDR36 Gene D658G sequence
            variant
  JOURNAL   Am J Ophthalmol 142 (2), 324-325 (2006)
   PUBMED   16876519
REFERENCE   7  (bases 1 to 3142)
  AUTHORS   Hauser,M.A., Allingham,R.R., Linkroum,K., Wang,J.,
            LaRocque-Abramson,K., Figueiredo,D., Santiago-Turla,C., del
            Bono,E.A., Haines,J.L., Pericak-Vance,M.A. and Wiggs,J.L.
  TITLE     Distribution of WDR36 DNA sequence variants in patients with
            primary open-angle glaucoma
  JOURNAL   Invest Ophthalmol Vis Sci 47 (6), 2542-2546 (2006)
   PUBMED   16723468
REFERENCE   8  (bases 1 to 3142)
  AUTHORS   Monemi,S., Spaeth,G., DaSilva,A., Popinchalk,S., Ilitchev,E.,
            Liebmann,J., Ritch,R., Heon,E., Crick,R.P., Child,A. and
            Sarfarazi,M.
  TITLE     Identification of a novel adult-onset primary open-angle glaucoma
            (POAG) gene on 5q22.1
  JOURNAL   Hum Mol Genet 14 (6), 725-733 (2005)
   PUBMED   15677485
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000018.1.
            
            On Jan 27, 2022 this sequence version replaced XM_039097400.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.73067.1,
                                           SRR26643285.51722.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-277               JAXUCZ010000018.1  24747832-24748108
            278-305             JAXUCZ010000018.1  24749945-24749972
            306-406             JAXUCZ010000018.1  24751453-24751553
            407-524             JAXUCZ010000018.1  24752305-24752422
            525-657             JAXUCZ010000018.1  24754298-24754430
            658-712             JAXUCZ010000018.1  24755980-24756034
            713-845             JAXUCZ010000018.1  24757197-24757329
            846-1021            JAXUCZ010000018.1  24757484-24757659
            1022-1142           JAXUCZ010000018.1  24757944-24758064
            1143-1208           JAXUCZ010000018.1  24758654-24758719
            1209-1295           JAXUCZ010000018.1  24759352-24759438
            1296-1441           JAXUCZ010000018.1  24760748-24760893
            1442-1556           JAXUCZ010000018.1  24762019-24762133
            1557-1722           JAXUCZ010000018.1  24762518-24762683
            1723-1831           JAXUCZ010000018.1  24762949-24763057
            1832-1911           JAXUCZ010000018.1  24765046-24765125
            1912-2019           JAXUCZ010000018.1  24769363-24769470
            2020-2117           JAXUCZ010000018.1  24771027-24771124
            2118-2263           JAXUCZ010000018.1  24771494-24771639
            2264-2383           JAXUCZ010000018.1  24772857-24772976
            2384-2465           JAXUCZ010000018.1  24773136-24773217
            2466-2653           JAXUCZ010000018.1  24774414-24774601
            2654-3142           JAXUCZ010000018.1  24775460-24775948
FEATURES             Location/Qualifiers
     source          1..3142
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18p12"
     gene            1..3142
                     /gene="Wdr36"
                     /note="WD repeat domain 36"
                     /db_xref="GeneID:688637"
                     /db_xref="RGD:1586463"
     exon            1..277
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     CDS             116..2803
                     /gene="Wdr36"
                     /codon_start=1
                     /product="WD repeat-containing protein 36"
                     /protein_id="NP_001387744.1"
                     /db_xref="GeneID:688637"
                     /db_xref="RGD:1586463"
                     /translation="MESAVEGRTASVLFAGFRALGLFSNDIPHVVRYNALKRRFYVTT
                     CVGKSFHTYDVQKLSLVAVSNSVPQDICCMAADGRLVFAAYGNVFSAFARNKEIVHTF
                     KGHKAEIHLLQPFGDHVISVDTDSVLIIWHIYSEEEYLQLTFDKSVFKISTILHPSTY
                     LNKVLLGSEQGSLQLWNIKSNKLLYTFPGWKVGVTALQQAPAVDVVAIGLVSGQVVIH
                     NIKFDETLMKFHQDWGPITSISFRTDGHPIMAAGSPCGHIGLWDLEDKKLINQMRNAH
                     STAISGLTFLHREPLLVTNGADNALRIWIFDGPTGEGRLLRLRMGHSASLTKIRYYGQ
                     NGQQILSASQDGTLQSFSTVHEKFNKSLGHGLVNKKIVKRKGLQNTMSVRLPPITQFA
                     AEEARQSDWDGVIACHQGKLSCSTWNYQRSTIGAYFLKPKNVKANSATATAVDITSCG
                     NFAIIGLSSGAVDVYNMQSGIHRGSFGDEKAHAGSVRGVAVDGLNQLAITAGSERLLK
                     FWNFKSKVLVHSLSLDSPPNVMLLHRDSGILGLALDDFSITVLDIETRKIVREFSGHQ
                     GQINDMTFSPDGRWLISAAMDCSVRTWDLPSGCLIDCFLLDSAPLNVTMSPTGDFLAT
                     SHVDHLGIYLWSNISLYSVVSLRPLPPDYVPSVLMLPGTCQTQGLEALEEQIEPSDEM
                     IEYESPEQLNEQLVTLSLLPESRWKNLLNLDVIKKKNKPKEPPKVPQSAPFFIPTVPG
                     LVPRFAVPEPTSDPQQSKVVNLGILAQKSNFYLKLEEGLQNNQYEGALNLLKELGPSG
                     IETELRNLSPEDGGSIEAMRSFLSMIGVMLDRKRDFELAQAYLALFLKLHLRMLPSEP
                     VLLEELVKLSSQVEEDWTHLQSLFNQSMCVLNYIKSALL"
     exon            278..305
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            306..406
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            407..524
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            525..657
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            658..712
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            713..845
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            846..1021
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1022..1142
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1208
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1295
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1296..1441
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1556
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1557..1722
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1723..1831
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1832..1911
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            1912..2019
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2020..2117
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2118..2263
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2264..2383
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2384..2465
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2466..2653
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
     exon            2654..3142
                     /gene="Wdr36"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cccggaagca ctcctcaatt tactccggca taggcttctc acgaggcttg ctggagcgcc
       61 tggtgagcac tttccacccg gccgcgagct gagcggagcc cggtctacgg cggagatgga
      121 gagcgctgtg gaaggccgca cggccagcgt gcttttcgcg gggttccggg ccttggggtt
      181 gttcagcaac gacattccac acgtggtgcg gtacaacgcg ctcaagcgcc gcttctacgt
      241 gacgacttgc gtaggcaaga gcttccacac atatgacgtt cagaaactta gtctggttgc
      301 agtaagtaac tctgttccac aggacatctg ttgcatggca gccgatggga ggctagtctt
      361 tgctgcctat gggaacgttt tctctgcatt tgcccgtaat aaagagatag tacatacttt
      421 taagggccat aaagcagaaa tccatctatt gcaacccttt ggggatcatg taatctcagt
      481 ggatactgac agcgttctta ttatttggca catttattca gaagaagagt accttcagtt
      541 gacttttgat aagtcagttt ttaaaatttc tacaattttg catccaagca cctacttgaa
      601 taaagttctc ctgggcagtg agcagggaag cctacagtta tggaatataa agtccaataa
      661 acttctatat acatttccag gatggaaggt gggagtaaca gctcttcagc aggcaccagc
      721 tgtggacgtg gtggccattg gtcttgtgtc tggtcaagtt gtcattcaca acattaagtt
      781 tgatgaaaca ttaatgaagt tccatcagga ttggggaccc attacttcca tttcatttcg
      841 tacagatggt catccaataa tggcagctgg aagcccgtgt ggccatattg gactctggga
      901 tctggaagat aaaaaattaa ttaatcaaat gagaaatgca cactctacag caatatctgg
      961 gctgacattt cttcatagag agccgttgct tgttacaaat ggcgctgata atgctcttag
     1021 gatatggata tttgatggcc cgacaggtga aggacggctg ttgagattaa gaatgggaca
     1081 tagtgcgtct cttaccaaga ttagatatta tggacaaaat ggacagcaga ttttaagtgc
     1141 aagtcaagac gggactctac agtcattttc tacagttcat gaaaaattca acaagagctt
     1201 ggggcatgga ttagtaaaca aaaaaatagt taaacgtaaa ggacttcaga acactatgtc
     1261 agtaagactt ccacctatca cacaatttgc tgctgaggaa gctcgccaaa gtgactggga
     1321 tggtgtcatt gcttgccatc aaggtaagct gtcttgctca acctggaatt accagagatc
     1381 tacaataggt gcttatttcc tcaagccaaa aaacgtaaag gcaaacagcg ccactgccac
     1441 agcagtagat ataacttcct gtggaaactt tgcaataatt ggcctctcct cgggagccgt
     1501 ggatgtgtac aacatgcagt ctggtataca tcgaggaagt tttggagatg agaaagctca
     1561 tgccggctct gtcagaggtg tcgccgtgga tggattgaac cagctggcaa ttacagctgg
     1621 aagtgaacgg ttgctcaaat tctggaactt caaaagcaag gttttggtcc actctctgag
     1681 ccttgattca cctccaaatg tgatgctgct gcacagggac agtggcatcc tgggccttgc
     1741 cttggatgac ttctccatta ctgttctcga catagaaact aggaagattg tcagagagtt
     1801 ttctggacac caaggccaaa taaatgacat gacgttcagt cctgatggcc gttggttgat
     1861 aagtgcggcg atggattgct ctgttaggac ttgggacctt ccctcagggt gcctaatcga
     1921 ctgttttttg ctggactctg ctcctctaaa tgttactatg tccccaactg gagactttct
     1981 agcaacgtcc catgtggatc accttggaat ttatctgtgg tcgaatattt ccctctattc
     2041 agttgtctcc ctgcgaccac ttcctccaga ttatgtccct tccgtactga tgcttcctgg
     2101 tacttgtcaa acccaaggtc tggaagcatt ggaagaacag attgagccaa gcgatgaaat
     2161 gatagagtat gagtcgccag agcagttgaa tgagcaactg gtgactctct cacttctccc
     2221 tgagtcacgc tggaaaaacc ttctgaatct tgatgttatc aagaaaaaga ataaaccaaa
     2281 agaaccaccc aaggttcccc agtcagctcc gttcttcatc ccaacagttc ccgggcttgt
     2341 ccccaggttt gctgtacctg aacccaccag tgacccccag cagtctaagg tggtaaacct
     2401 tgggattttg gctcaaaaat caaatttcta cctgaaactt gaagaaggat tacaaaataa
     2461 tcagtatgaa ggggctctta accttctgaa agagttaggc ccgtctggga ttgaaacgga
     2521 gctgcggaac ttgtctcctg aggacggcgg gtcaatagag gccatgcgga gctttttgag
     2581 tatgatcggg gtgatgctgg acagaaagcg tgatttcgag ctggcccagg cgtaccttgc
     2641 attgtttctg aagttacacc tcagaatgct tccttcggag ccagtgcttt tagaggagct
     2701 ggtgaagttg tcatcacagg tagaagaaga ttggactcac ttacagtcac tcttcaatca
     2761 aagcatgtgt gtcttaaatt atatcaaaag tgctttgttg taaaaaaaaa taataaaaaa
     2821 cgtaagtggt tacagaaatc aaactatatg tgaagtgtgc tgtttaactt catcccagct
     2881 cagcatggag tgagcagcta gtgtagtgta agtgctttaa agcctttgta cacaggaaat
     2941 tgtacctttt tattctgctc tgcacaccaa gagaacttaa aactacctga gttcgtcaca
     3001 agagtcacat atgtgaatta ttgccacttt gtattttttc atgttatgta taaaagactg
     3061 cctatttagt gtgttttact gaattaaatt gacaatgtca gataaagcag atctataata
     3121 tacttactaa aaatgctttt at
//
